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Host-Pathogen Seminar Series 2012-2013



September 10, 2012

Samuel I. Miller, MD, Professor of Medicine, Microbiology, and Genome Sciences; Director, Research Center of Excellence in Biodefense and Emerging Infectious Diseases; Director, Cystic Fibrosis Research and Development Program, University of Washington

"Are pathogenic bacteria just looking for food? The evolutionary interplay between humans and bacteria"

Dr. Samuel Miller’s research focuses on the evolution of Pseudomonas aeruginosa in the airways of Cystic Fibrosis and how the organism through loss of function mutations adapts to the increased nutrient environment of the CF airway. Dr. Miller’s laboratory uses a technology that allows cellular GWAS (Genome wide association studies) to be performed. This technology defines human genome diversity that results in more robust inflammatory responses to bacteria. These human polymorphisms have relevance for human infectious and inflammatory diseases and have led to an evolutionary model for their selection as the human population has increased.


Co-Sponsored with the Department of Microbial Infection and Immunity and Public Health Preparedness for Infectious Diseases (PHPID)

November 5, 2012    

Hank Seifert, PhD, Professor and Associate Chair, Department of Microbiology-Immunology, Northwestern University's Feinberg School of Medicine

"Mechanisms used by Neisseria gonorrhoeae to co-exist with human innate and adaptive immune systems"

The pathogenic and commensal Neisseria are host-adapted organisms that have evolved within the human population for thousands of years. The pathogenic species, Neisseria gonorrhoeae and Neisseria meningitidis can cause serious disease, due to the induction of inflammation and transits to inopportune anatomical sites. As effective pathogens, these bacteria have evolved ways to successfully interact with the human innate and adaptive immune systems to promote infection and disease, and our research group studies the mechanisms underlying different aspects of these host-pathogen interactions.


Co-Sponsored with The Research Institute at Nationwide Children's Hospital, Center for Microbial Pathogenesis, and by the Departments of Microbiology and Microbial Infection & Immunity



April 8, 2013

Nicole Baumgarth, DVM, PhD, Professor & Chancellor's Fellow, Center for Comparative Medicine; Chair, Graduate Group in Immunology, University of California

"A case of memory loss: Local humoral responses to influenza virus infection"


Co-Sponsored with the Department of Microbial Infection and Immunity

May 13, 2013

Joseph Sodroski, MD, Professor, Microbiology and Immunobiology, Dana-Farber Cancer Institute, Harvard Medical School

"Structure and Neutralization of the HIV-1 Envelope Glycoprotein Trimer"


Co-Sponsored with the Department of Microbial Infection and Immunity, Dept. of Veterinary Biosciences, Center for Retrovirus Research and Ohio Agricultural Research and Development Center
September 24, 2013
Pradeep Singh
Associate Professor of Microbiology
University of Washington