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Yasuko Rikihisa, PhD


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1925 Coffey Rd
Columbus, OH 43210

Phone: (614) 292-9677

Email: rikihisa.1@osu.edu

 

Current OSU Appointment

Professor, Veterinary Biosciences

 

Chapters in Books

Ito, S. and Y. Rikihisa. "Techniques for electron microscopy of rickettsiae." In Rickettsiae and Rickettsial Diseases. -. Amsterdam: Academic Press (Elsevier), January 1981.

Rikihisa, Y. and S. Ito. "Outer membrane vesicles of Rickettsia tsutsugamushi in baby hamster kidney cells." In Rickettsiae and Rickettsial Diseases. -. Amsterdam: Academic Press (Elsevier), January 1981.

Rikihisa. "Classification and Morphology of bacteria and fungi." In Essentials of Veterinary Bacteriology and Mycology. -. Phildadelphia: Lea and Febiger, January 1986.

Rikihisa, Y. "Ultrastructural studies of ehrlichial organisms in the organs of ponies with equine monocytic ehrlichiosis (synonym, Potomac horse fever)." In Microbiology 1986. -. Washington, DC: American Society for Microbiology, January 1986.

Rikihisa, Y. "Ultrastructure of rickettsiae with special emphasis on ehrlichia." In Current Topics in Veterinary Medicine and Animal Sciences. -. Norwell: Kluwer, January 1990.

Rikihisa, Y. "Classification and Morphology of Bacteria and Fungi." In Essentials of Veterinary Bacteriology, Mycology, and. -. Philadelphia: Lee and Febiger, January 1995.

Rikihisa, Y. and G. Zimmerman. "Salmon poisoning disease." In Current Veterinary Therapy XII Small Animal Practice. -. W.B. Saunders: Phildadelphia, January 1995.

Rikihisa, Y. "Ehrlichiae." In Rickettsiae and Rickettsial Diseases. -. Bratislava: International Society of Rickettsiae and Rickettsial Diseases, January 1996.

Rikihisa, Y. "Rickettsial diseases in horses." In Equine Internal Medicine. -. Amsterdam: WB Saunders/Elsevier, January 1997.

Rikihisa, Y. "Ehrlichiae of Veterinary Importance." In Rickettsiae and Rickettsial Diseases at the Turn of the Third Millenium. -. Paris: Elsevier, January 1999.

Rikihisa, Y. "Analysis of pathogenesis of human ehrlichiosis." In Latent Pathogen. -. Tokyo: Saikon, January 2000.

Rikihisa, Y. "Ehrlichial strategy for survival and proliferation in the leukocytes." In Subcellular Biochemistry: Bacterial invasion into eukaryotic cells. -. New York: Plenum Publishing, January 2000.

Hechemy, K.E. and Y. Rikihisa. "Immunoserology of Rickettsiales, Bartonella, and Coxiella." In Manual of Clinical Laboratory Immunology. -. Washington, DC: ASM Press, January 2002.

Waites, K. B., Y. Rikihisa, and D. Taylor-Robinson. "Mycoplasma and Ureaplasma." In Manual of Clinical Microbiology. -. Washington, DC: American Society for Microbiology, January 2003.

Rikihisa, Y. "Rickettsial diseases." In Equine Internal Medicine.. -. Amsterdam: WB Saunders (Elsevier), January 2004.

Dumler, J.S., Y. Rikihisa, and G.A. Dasch. "Anaplasma." In Bergey's Manual of Systematic Bacteriology. -. New York: Springer, January 2005.

Rikihisa, Y. J.S. Dumler and G.A. Dasch. "Neorickettsia." In Bergey's Manual of Systematic Bacteriology. -. New york: Springer, January 2005.

Dumler, J.S., Y. Rikihisa, and G.A. Dasch. "Ehrlicihia." In Bergey's Manual of Systematic Bacteriology. -. New York: Springer, January 2005.

Rikihisa, Y. and Kreier, J.P.. "Aegyptainella." In Bergey's Manual of Systematic Bacteriology. -. New Yorl: Springer, January 2005.

Dumler, J.S., Y. Rikihisa, and G.A. Dasch. "Anaplasmataceae." In Bergey's Manual of Systematic Bacteriology. -. New York: Springer, January 2005.

Hechemy, K.E. Y. Rikihisa, K. Macaluso, A. W. O. Burgess, B. E. Anderson, and H. A. Thompson. "The Rickettsiaceae, Anaplasmataceae, Bartonellaceae, and Coxiellaceae." In Manual of Clinical Laboratory Immunology. -. Washington, D.C.: American Society for Microbiology Press, January 2006.

Rikihisa, Y. "Rickettsiology: Present and Future." In Contemporary State of The Rickettsioses in the World and in Bulgaria. -. Weinheim: 3. Wiley-VCH, January 2007.

Rikihisa, Y. "Ehrlichia, Anaplasma." In Intracellular Niches of Pathogens—A microbe’s Guide through the host cell. Edited by Ulrich E. Schaible and Albert Haas. -. Weinheim, DE|DEU: Wiley-VCH Publishers, January 2009.

Rikihisa, Y. "The family Anaplasmataceae." In Pathogenic bacteria, virus. -. Hokkaido, JP|JPN: Hokkaido University press, January 2011.

 

Honors

1984 Teaching Excellence Award.
1989 World Bank Higher Education XVII Award. Midwestern Universities Consortium for International Activities.
1992 Smith Kline-Beecgan Award for Research Excellence.
1997 Japan Society of Promotion of Science Award.
1997 Animal Health Award for Research Excellence.
1999 Distinguished Scholar Award.
1999 Distinguished Scholar Award. Office of Research.
2000 Emerging and Reemerging Infectious Diseases Award.
2001 Teaching Excellence for Graduate Education.
2001 Charles C Capen Teaching Excellence Award.
2004 - 2007 David White Research Award.
2005 AAAS Fellow.
2009 AAM Fellow.
2010 Japan Society of Promotion of Science.
 

Journal Articles

Rikihisa, Y; Ohkuma, S; Mizuno, D. "Antigenic differences between the outer and inner surfaces of plasma membranes of polymorphonuclear leukocytes shown with immunoferritin.." Experimental cell research. Vol. 100, no. 1. (January 1976.): 23-30.

Rikihisa, Y; Mizuno, D. "Demonstration of myosin on the cytoplasmic side of plasma membranes of guinea pig polymorphonuclear leukocytes with immunoferritin.." Experimental cell research. Vol. 110, no. 1. (January 1977.): 87-92.

Rikihisa, Y; Mizuno, D. "Binding of markers of either side of plasma membranes to the cytoplasmic side of paraffin oil-loaded phagolysosomes.." Experimental cell research. Vol. 110, no. 1. (January 1977.): 93-101.

Rikihisa, Y; Mizuno, D. "Binding of markers of either side of plasma membranes to the cytoplasmic side of lysosomes.." Experimental cell research. Vol. 110, no. 1. (January 1977.): 103-10.

Rikihisa, Y; Mizuno, D. "Different arrangements of phagolysosome membranes which depend upon the particles phagocytized. Observation with markers of the two sides of plasma membranes.." Experimental cell research. Vol. 111, no. 2. (January 1978.): 437-49.

Rikihisa, Y; Ito, S. "Intracellular localization of Rickettsia tsutsugamushi in polymorphonuclear leukocytes.." The Journal of experimental medicine. Vol. 150, no. 3. (January 1979.): 703-8.

Onitsuka, M, O; Rikihisa, Y; Maruyama, H B. "Biochemical and topographical studies on Escherichia coli cell surface. IV. Giant spheroplast formation from a filamentous cell.." Journal of bacteriology. Vol. 138, no. 2. (January 1979.): 567-74.

Rikihisa, Y; Rota, T; Lee, T, H; MacDonald, A, B; Ito, S. "Changes in immunoferritin labeling of Rickettsia tsutsugamushi after serial cultivation in 60Co-irradiated BHK cells.." Infection and immunity. Vol. 26, no. 2. (January 1979.): 638-50.

Rikihisa, Y; Ito, S. "Localization of electron-dense tracers during entry of Rickettsia tsutsugamushi into polymorphonuclear leukocytes.." Infection and immunity. Vol. 30, no. 1. (January 1980.): 231-43.

Rikihisa, Y; Ito, S. "Entry of Rickettsia tsutsugamushi into polymorphonuclear leukocytes.." Infection and immunity. Vol. 38, no. 1. (January 1982.): 343-50.

Rikihisa, Y; Ito, S. "Effect of antibody on entry of Rickettsia tsutsugamushi into polymorphonuclear leukocyte cytoplasm.." Infection and immunity. Vol. 39, no. 2. (January 1983.): 928-38.

Rikihisa, Y; Perry, B; Cordes, D. "Rickettsial link with acute equine diarrhoea.." The Veterinary record. Vol. 115, no. 15. (January 1984.): 390-.

Rikihisa, Y; Lin, Y C. "Taenia taeniaeformis: increased cell growth and neutral mucus production in the gastric mucosa of the rat with a larval infection.." Experimental parasitology. Vol. 58, no. 2. (January 1984.): 147-55.

Rikihisa, Y; Letonja, T; Pratt, N; Chin Lin, Y. "Taenia taeniaeformis: characterization of larval metabolic products and growth of host gastric cells in vitro.." Experimental parasitology. Vol. 58, no. 3. (January 1984.): 230-8.

Rikihisa, Y. "Glycogen autophagosomes in polymorphonuclear leukocytes induced by rickettsiae.." The Anatomical record. Vol. 208, no. 3. (January 1984.): 319-27.

Hammerberg, B; Rikihisa, Y; King, M W. "Immunoglobulin interactions with surfaces of sheathed and unsheathed microfilariae.." Parasite immunology. Vol. 6, no. 5. (January 1984.): 421-34.

Letonja, T; Rikihisa, Y; Hammerberg, C. "Differential cellular response of resistant and susceptible rodents to the early stages of infection of Taenia taeniaeformis.." International journal for parasitology. Vol. 14, no. 6. (January 1984.): 551-8.

Rikihisa, Y; Perry, B, D; Cordes, D O. "Ultrastructural study of ehrlichial organisms in the large colons of ponies infected with Potomac horse fever.." Infection and immunity. Vol. 49, no. 3. (January 1985.): 505-12.

Rikihisa, Y; Perry, B D. "Causative ehrlichial organisms in Potomac horse fever.." Infection and immunity. Vol. 49, no. 3. (January 1985.): 513-7.

Rikihisa, Y; Lin, Y, C; Walton, A. "Histopathologic changes of uterus following gossypol treatment during early pregnancy in rats.." The Anatomical record. Vol. 213, no. 1. (January 1985.): 72-6.

Rikihisa, Y; Lin, Y, C; Fukaya, T. "Taenia taeniaeformis: inhibition of rat testosterone production by excretory-secretory product of the cultured metacestode.." Experimental parasitology. Vol. 59, no. 3. (January 1985.): 390-7.

Rikihisa, Y. "Ultrastructural localization of carbonic anhydrase in lysosomes.." The Anatomical record. Vol. 211, no. 1. (January 1985.): 1-8.

Lin, Y, C; Fukaya, T; Rikihisa, Y; Walton, A. "Gossypol in female fertility control: ovum implantation and early pregnancy inhibited in rats.." Life sciences. Vol. 37, no. 1. (January 1985.): 39-47.

Lin, Y, C; Fukaya, T; Rikihisa, Y. "Effects of age and luteinizing hormone antiserum on human chorionic gonadotropin-stimulated testosterone secretion in young male rats.." Life sciences. Vol. 37, no. 5. (January 1985.): 481-8.

Blohowiak, C, C; De Santo, T, L; Rikihisa, Y; Lin, Y C. "Diurnal, premating, and postmating testosterone levels in roosters genetically selected for mating frequency.." Poultry science. Vol. 64, no. 5. (January 1985.): 1028-30.

Perry, B, D; Rikihisa, Y; Saunders, G K. "Intradermal transmission of Potomac horse fever.." The Veterinary record. Vol. 116, no. 9. (January 1985.): 246-7.

Hammerberg, C; Hollingshead, M; Rikihisa, Y; Debuysscher, E V. "Porcine lymphoblastoid cell lines of B-cell origin.." Veterinary immunology and immunopathology. Vol. 10, no. 4. (January 1985.): 367-80.

King, C, S; Lin, Y, C; Fukaya, T; Rikihisa, Y. "In vivo and in vitro inhibition of human chorionic gonadotropin-induced testosterone production in rat testis by bursa of fabricius extract.." Poultry science. Vol. 64, no. 6. (January 1985.): 1223-6.

Steele, K, E; Rikihisa, Y; Walton, A M. "Ehrlichia of Potomac horse fever identified with a silver stain.." Veterinary pathology. Vol. 23, no. 4. (January 1986.): 531-3.

Burger, C, J; Rikihisa, Y; Lin, Y C. "Taenia taeniaeformis: inhibition of mitogen induced proliferation and interleukin-2 production in rat splenocytes by larval in vitro product.." Experimental parasitology. Vol. 62, no. 2. (January 1986.): 216-22.

Cordes, D, O; Perry, B, D; Rikihisa, Y; Chickering, W R. "Enterocolitis caused by Ehrlichia sp. in the horse (Potomac horse fever).." Veterinary pathology. Vol. 23, no. 4. (January 1986.): 471-7.

Rikihisa, Y; Lin, Y, C; Walton, A. "Taenia taeniaeformis: immunoperoxidase localization of metacestode culture product(s) in hyperplastic gastric mucosa.." Experimental parasitology. Vol. 61, no. 2. (January 1986.): 134-7.

Rikihisa, Y; Lin, Y C. "Taenia taeniaeformis: inhibition of metacestode development in the rat by gossypol.." Experimental parasitology. Vol. 61, no. 2. (January 1986.): 127-33.

Pretzman, C, I; Rikihisa, Y; Ralph, D; Gordon, J, C; Bech-Nielsen, S. "Enzyme-linked immunosorbent assay for Potomac horse fever disease.." Journal of clinical microbiology. Vol. 25, no. 1. (January 1987.): 31-6.

Lin, Y, C; Chitcharoenthum, M; Rikihisa, Y. "Effect of gossypol on spermatozoal lactate dehydrogenase-X (LDH-X) in male rats.." Contraception. Vol. 36, no. 5. (January 1987.): 581-92.

Rikihisa, Y; Johnson, G, C; Burger, C J. "Reduced immune responsiveness and lymphoid depletion in mice infected with Ehrlichia risticii.." Infection and immunity. Vol. 55, no. 9. (January 1987.): 2215-22.

Wells, M, Y; Rikihisa, Y. "Lack of lysosomal fusion with phagosomes containing Ehrlichia risticii in P388D1 cells: abrogation of inhibition with oxytetracycline.." Infection and immunity. Vol. 56, no. 12. (January 1988.): 3209-15.

Rikihisa, Y; Pretzman, C, I; Johnson, G, C; Reed, S, M; Yamamoto, S; Andrews, F. "Clinical, histopathological, and immunological responses of ponies to Ehrlichia sennetsu and subsequent Ehrlichia risticii challenge.." Infection and immunity. Vol. 56, no. 11. (January 1988.): 2960-6.

Rikihisa, Y; Lin, Y C. "Ultrastructure of the testis and epididymis of Japanese quail (Coturnix coturnix japonica) administered gossypol.." Poultry science. Vol. 67, no. 6. (January 1988.): 961-72.

Rikihisa, Y; Jiang, B M. "In vitro susceptibilities of Ehrlichia risticii to eight antibiotics.." Antimicrobial agents and chemotherapy. Vol. 32, no. 7. (January 1988.): 986-91.

Lin, Y, C; Dietrick, T; Rikihisa, Y; Beane, W L. "Antifertility effect of gossypol in male Japanese quail.." Life sciences. Vol. 42, no. 22. (January 1988.): 2283-92.

Rikihisa, Y; Lin, Y C. "Effect of gossypol on the thyroid in young rats.." Journal of comparative pathology. Vol. 100, no. 4. (January 1989.): 411-7.

Rikihisa, Y; Jiang, B M. "Effect of antibiotics on clinical, pathologic and immunologic responses in murine Potomac horse fever: protective effects of doxycycline.." Veterinary microbiology. Vol. 19, no. 3. (January 1989.): 253-62.

Rikihisa, Y; Reed, S, M; Sams, R, A; Gordon, J, C; Pretzman, C I. "Serosurvey of horses with evidence of equine monocytic ehrlichiosis.." Journal of the American Veterinary Medical Association. Vol. 197, no. 10. (January 1990.): 1327-32.

Rikihisa, Y; Lin, Y, C; Garber, P, L; Gu, Y. "Taenia taeniaeformis: inactivation of metacestodes by gossypol in vitro.." Experimental parasitology. Vol. 71, no. 2. (January 1990.): 135-45.

Rikihisa, Y. "Growth of Ehrlichia risticii in human colonic epithelial cells.." Annals of the New York Academy of Sciences. Vol. 590, (January 1990.): 104-10.

Lin, Y, C; Rikihisa, Y; Kono, H; Gu, Y. "Effects of larval tapeworm (Taenia taeniaeformis) infection on reproductive functions in male and female host rats.." Experimental parasitology. Vol. 70, no. 3. (January 1990.): 344-52.

Lin, Y, C; Chitcharoenthum, M; Rikihisa, Y. "Effect of gossypol on thyroid hormones in young female rats.." Contraception. Vol. 41, no. 4. (January 1990.): 431-40.

Gu, Y; Lin, Y, C; Rikihisa, Y. "Inhibitory effect of gossypol on steroidogenic pathways in cultured bovine luteal cells.." Biochemical and biophysical research communications. Vol. 169, no. 2. (January 1990.): 455-61.

Gu, Y; Chang, C, J; Rikihisa, Y; Lin, Y C. "Inhibitory effect of gossypol on human chorionic gonadotropin (hCG)-induced progesterone secretion in cultured bovine luteal cells.." Life sciences. Vol. 47, no. 5. (January 1990.): 407-14.

Gu, Y; Li, P, K; Lin, Y, C; Rikihisa, Y; Brueggemeier, R W. "Gossypolone suppresses progesterone synthesis in bovine luteal cells.." The Journal of steroid biochemistry and molecular biology. Vol. 38, no. 6. (January 1991.): 709-15.

Park, J; Rikihisa, Y. "Inhibition of Ehrlichia risticii infection in murine peritoneal macrophages by gamma interferon, a calcium ionophore, and concanavalin A.." Infection and immunity. Vol. 59, no. 10. (January 1991.): 3418-23.

Rikihisa, Y; Stills, H; Zimmerman, G. "Isolation and continuous culture of Neorickettsia helminthoeca in a macrophage cell line.." Journal of clinical microbiology. Vol. 29, no. 9. (January 1991.): 1928-33.

Rikihisa, Y. "The tribe Ehrlichieae and ehrlichial diseases.." Clinical microbiology reviews. Vol. 4, no. 3. (January 1991.): 286-308.

Rikihisa, Y. "Protection against murine potomac horse fever by an inactivated Ehrlichia risticii vaccine.." Veterinary microbiology. Vol. 27, no. 3-4. (January 1991.): 339-50.

Rikihisa, Y. "Cross-reacting antigens between Neorickettsia helminthoeca and Ehrlichia species, shown by immunofluorescence and Western immunoblotting.." Journal of clinical microbiology. Vol. 29, no. 9. (January 1991.): 2024-9.

Dawson, J, E; Rikihisa, Y; Ewing, S, A; Fishbein, D B. "Serologic diagnosis of human ehrlichiosis using two Ehrlichia canis isolates.." The Journal of infectious diseases. Vol. 163, no. 3. (January 1991.): 564-7.

Chang, C, J; Lin, Y, C; Brueggemeier, R, W; Rikihisa, Y. "Morphometric analysis of renal cortex changes induced by diethylstilbestrol (DES) in Syrian hamsters.." Research communications in chemical pathology and pharmacology. Vol. 78, no. 3. (January 1992.): 341-58.

Lin, Y, C; Gu, Y; Brueggemeier, R, W; Rikihisa, Y. "Binding of 3H-gossypol in organelles of cultured bovine luteal cells.." Life sciences. Vol. 50, no. 6. (January 1992.): 443-7.

Park, J; Rikihisa, Y. "L-arginine-dependent killing of intracellular Ehrlichia risticii by macrophages treated with gamma interferon.." Infection and immunity. Vol. 60, no. 9. (January 1992.): 3504-8.

Budiarso, I, T; Rikihisa, Y. "Vascular lesions in lungs of Bali cattle with Jembrana disease.." Veterinary pathology. Vol. 29, no. 3. (January 1992.): 210-5.

Riond, J, L; Riviere, J, E; Duckett, W, M; Atkins, C, E; Jernigan, A, D; Rikihisa, Y; Spurlock, S L. "Cardiovascular effects and fatalities associated with intravenous administration of doxycycline to horses and ponies.." Equine veterinary journal. Vol. 24, no. 1. (January 1992.): 41-5.

Rikihisa, Y; Johnson, G, C; Wang, Y, Z; Reed, S, M; Fertel, R; Cooke, H J. "Loss of absorptive capacity for sodium and chloride in the colon causes diarrhoea in Potomac horse fever.." Research in veterinary science. Vol. 52, no. 3. (January 1992.): 353-62.

Rikihisa, Y; Ewing, S, A; Fox, J, C; Siregar, A, G; Pasaribu, F, H; Malole, M B. "Analyses of Ehrlichia canis and a canine granulocytic Ehrlichia infection.." Journal of clinical microbiology. Vol. 30, no. 1. (January 1992.): 143-8.

Messick, J, B; Rikihisa, Y. "Suppression of Ia antigen expression on gamma interferon treated macrophages infected with Ehrlichia risticii.." Veterinary immunology and immunopathology. Vol. 32, no. 3-4. (January 1992.): 225-41.

Messick, J, B; Rikihisa, Y. "Presence of parasite antigen on the surface of P388D1 cells infected with Ehrlichia risticii.." Infection and immunity. Vol. 60, no. 8. (January 1992.): 3079-86.

Kulp, S, K; Rikihisa, Y; Lin, Y, C; Moh, P, P; Li, P, K; Gu, Y. "In vitro uptake and autoradiographic localization of tritiated gossypol in Taenia taeniaeformis metacestodes.." Parasitology research. Vol. 79, no. 4. (January 1993.): 279-85.

van Heeckeren, A, M; Rikihisa, Y; Park, J; Fertel, R. "Tumor necrosis factor alpha, interleukin-1 alpha, interleukin-6, and prostaglandin E2 production in murine peritoneal macrophages infected with Ehrlichia risticii.." Infection and immunity. Vol. 61, no. 10. (January 1993.): 4333-7.

Rikihisa, Y; Wada, R; Reed, S, M; Yamamoto, S. "Development of neutralizing antibody in horses infected with Ehrlichia risticii.." Veterinary microbiology. Vol. 36, no. 1-2. (January 1993.): 139-47.

Messick, J, B; Rikihisa, Y. "Characterization of Ehrlichia risticii binding, internalization, and proliferation in host cells by flow cytometry.." Infection and immunity. Vol. 61, no. 9. (January 1993.): 3803-10.

Kawahara, M; Suto, C; Rikihisa, Y; Yamamoto, S; Tsuboi, Y. "Characterization of ehrlichial organisms isolated from a wild mouse.." Journal of clinical microbiology. Vol. 31, no. 1. (January 1993.): 89-96.

Yamamoto, S; Shida, T; Honda, M; Ashida, Y; Rikihisa, Y; Odakura, M; Hayashi, S; Nomura, M; Isayama, Y. "Serum C-reactive protein and immune responses in dogs inoculated with Bordetella bronchiseptica (phase I cells).." Veterinary research communications. Vol. 18, no. 5. (January 1994.): 347-57.

Yamamoto, S; Miyaji, S; Ashida, Y; Otabe, K; Momotani, E; Rikihisa, Y. "Preparation of anti-canine serum amyloid A (SAA) serum and purification of SAA from canine high-density lipoprotein.." Veterinary immunology and immunopathology. Vol. 41, no. 1-2. (January 1994.): 41-53.

Lin, Y, C; Sanbuissho, A; Coskun, S; Rikihisa, Y. "Inhibition of in vitro fertilization and early embryonic development in hamsters by gossypol.." Life sciences. Vol. 55, no. 14. (January 1994.): 1139-45.

Chaichanasiriwithaya, W; Rikihisa, Y; Yamamoto, S; Reed, S; Crawford, T, B; Perryman, L, E; Palmer, G H. "Antigenic, morphologic, and molecular characterization of new Ehrlichia risticii isolates.." Journal of clinical microbiology. Vol. 32, no. 12. (January 1994.): 3026-33.

Barnewall, R, E; Rikihisa, Y. "Abrogation of gamma interferon-induced inhibition of Ehrlichia chaffeensis infection in human monocytes with iron-transferrin.." Infection and immunity. Vol. 62, no. 11. (January 1994.): 4804-10.

Rikihisa, Y; Zhang, Y; Park, J. "Inhibition of infection of macrophages with Ehrlichia risticii by cytochalasins, monodansylcadaverine, and taxol.." Infection and immunity. Vol. 62, no. 11. (January 1994.): 5126-32.

Rikihisa, Y; Yamamoto, S; Kwak, I; Iqbal, Z; Kociba, G; Mott, J; Chichanasiriwithaya, W. "C-reactive protein and alpha 1-acid glycoprotein levels in dogs infected with Ehrlichia canis.." Journal of clinical microbiology. Vol. 32, no. 4. (January 1994.): 912-7.

Rikihisa, Y; Ewing, S, A; Fox, J C. "Western immunoblot analysis of Ehrlichia chaffeensis, E. canis, or E. ewingii infections in dogs and humans.." Journal of clinical microbiology. Vol. 32, no. 9. (January 1994.): 2107-12.

Messick, J, B; Rikihisa, Y. "Inhibition of binding, entry, or intracellular proliferation of Ehrlichia risticii in P388D1 cells by anti-E. risticii serum, immunoglobulin G, or Fab fragment.." Infection and immunity. Vol. 62, no. 8. (January 1994.): 3156-61.

Iqbal, Z; Rikihisa, Y. "Reisolation of Ehrlichia canis from blood and tissues of dogs after doxycycline treatment.." Journal of clinical microbiology. Vol. 32, no. 7. (January 1994.): 1644-9.

Iqbal, Z; Rikihisa, Y. "Application of the polymerase chain reaction for the detection of Ehrlichia canis in tissues of dogs.." Veterinary microbiology. Vol. 42, no. 4. (January 1994.): 281-7.

Iqbal, Z; Chaichanasiriwithaya, W; Rikihisa, Y. "Comparison of PCR with other tests for early diagnosis of canine ehrlichiosis.." Journal of clinical microbiology. Vol. 32, no. 7. (January 1994.): 1658-62.

Wen, B; Rikihisa, Y; Mott, J; Fuerst, P, A; Kawahara, M; Suto, C. "Ehrlichia muris sp. nov., identified on the basis of 16S rRNA base sequences and serological, morphological, and biological characteristics.." International journal of systematic bacteriology. Vol. 45, no. 2. (January 1995.): 250-4.

Wen, B; Rikihisa, Y; Fuerst, P, A; Chaichanasiriwithaya, W. "Diversity of 16S rRNA genes of new Ehrlichia strains isolated from horses with clinical signs of Potomac horse fever.." International journal of systematic bacteriology. Vol. 45, no. 2. (January 1995.): 315-8.

Rikihisa, Y; Zhang, Y; Park, J. "Role of Ca2+ and calmodulin in ehrlichial infection in macrophages.." Infection and immunity. Vol. 63, no. 6. (January 1995.): 2310-6.

Pretzman, C; Ralph, D; Stothard, D, R; Fuerst, P, A; Rikihisa, Y. "16S rRNA gene sequence of Neorickettsia helminthoeca and its phylogenetic alignment with members of the genus Ehrlichia.." International journal of systematic bacteriology. Vol. 45, no. 2. (January 1995.): 207-11.

Madigan, J, E; Rikihisa, Y; Palmer, J, E; DeRock, E; Mott, J. "Evidence for a high rate of false-positive results with the indirect fluorescent antibody test for Ehrlichia risticii antibody in horses.." Journal of the American Veterinary Medical Association. Vol. 207, no. 11. (January 1995.): 1448-53.

Wen, B; Rikihisa, Y; Yamamoto, S; Kawabata, N; Fuerst, P A. "Characterization of the SF agent, an Ehrlichia sp. isolated from the fluke Stellantchasmus falcatus, by 16S rRNA base sequence, serological, and morphological analyses.." International journal of systematic bacteriology. Vol. 46, no. 1. (January 1996.): 149-54.

Lee, E, H; Rikihisa, Y. "Absence of tumor necrosis factor alpha, interleukin-6 (IL-6), and granulocyte-macrophage colony-stimulating factor expression but presence of IL-1beta, IL-8, and IL-10 expression in human monocytes exposed to viable or killed Ehrlichia." Infection and immunity. Vol. 64, no. 10. (January 1996.): 4211-9.

Perez, M; Rikihisa, Y; Wen, B. "Ehrlichia canis-like agent isolated from a man in Venezuela: antigenic and genetic characterization.." Journal of clinical microbiology. Vol. 34, no. 9. (January 1996.): 2133-9.

Kawahara, M; Suto, C; Shibata, S; Futohashi, M; Rikihisa, Y. "Impaired antigen specific responses and enhanced polyclonal stimulation in mice infected with Ehrlichia muris.." Microbiology and immunology. Vol. 40, no. 8. (January 1996.): 575-81.

Rikihisa, Y; Zhi, N; Wormser, G, P; Wen, B; Horowitz, H, W; Hechemy, K E. "Ultrastructural and antigenic characterization of a granulocytic ehrlichiosis agent directly isolated and stably cultivated from a patient in New York state.." The Journal of infectious diseases. Vol. 175, no. 1. (January 1997.): 210-3.

Rikihisa, Y; Kawahara, M; Wen, B; Kociba, G; Fuerst, P; Kawamori, F; Suto, C; Shibata, S; Futohashi, M. "Western immunoblot analysis of Haemobartonella muris and comparison of 16S rRNA gene sequences of H. muris, H. felis, and Eperythrozoon suis.." Journal of clinical microbiology. Vol. 35, no. 4. (January 1997.): 823-9.

Lee, E, H; Rikihisa, Y. "Anti-Ehrlichia chaffeensis antibody complexed with E. chaffeensis induces potent proinflammatory cytokine mRNA expression in human monocytes through sustained reduction of IkappaB-alpha and activation of NF-kappaB.." Infection and immunity. Vol. 65, no. 7. (January 1997.): 2890-7.

Zhi, N; Rikihisa, Y; Kim, H, Y; Wormser, G, P; Horowitz, H W. "Comparison of major antigenic proteins of six strains of the human granulocytic ehrlichiosis agent by Western immunoblot analysis.." Journal of clinical microbiology. Vol. 35, no. 10. (January 1997.): 2606-11.

Zhang, Y; Rikihisa, Y. "Tyrosine phosphorylation is required for ehrlichial internalization and replication in P388D1 cells.." Infection and immunity. Vol. 65, no. 7. (January 1997.): 2959-64.

Zhang, Y; Ohashi, N; Lee, E, H; Tamura, A; Rikihisa, Y. "Ehrlichia sennetsu groE operon and antigenic properties of the GroEL homolog.." FEMS immunology and medical microbiology. Vol. 18, no. 1. (January 1997.): 39-46.

Mott, J; Rikihisa, Y; Zhang, Y; Reed, S, M; Yu, C Y. "Comparison of PCR and culture to the indirect fluorescent-antibody test for diagnosis of Potomac horse fever.." Journal of clinical microbiology. Vol. 35, no. 9. (January 1997.): 2215-9.

Barnewall, R, E; Rikihisa, Y; Lee, E H. "Ehrlichia chaffeensis inclusions are early endosomes which selectively accumulate transferrin receptor.." Infection and immunity. Vol. 65, no. 4. (January 1997.): 1455-61.

Barlough, J, E; Rikihisa, Y; Madigan, J E. "Nested polymerase chain reaction for detection of Ehrlichia risticii genomic DNA in infected horses.." Veterinary parasitology. Vol. 68, no. 4. (January 1997.): 367-73.

Wen, B; Rikihisa, Y; Mott, J, M; Greene, R; Kim, H, Y; Zhi, N; Couto, G, C; Unver, A; Bartsch, R. "Comparison of nested PCR with immunofluorescent-antibody assay for detection of Ehrlichia canis infection in dogs treated with doxycycline.." Journal of clinical microbiology. Vol. 35, no. 7. (January 1997.): 1852-5.

Zhi, N; Ohashi, N; Rikihisa, Y; Horowitz, H, W; Wormser, G, P; Hechemy, K. "Cloning and expression of the 44-kilodalton major outer membrane protein gene of the human granulocytic ehrlichiosis agent and application of the recombinant protein to serodiagnosis.." Journal of clinical microbiology. Vol. 36, no. 6. (January 1998.): 1666-73.

Kim, H, Y; Rikihisa, Y. "Characterization of monoclonal antibodies to the 44-kilodalton major outer membrane protein of the human granulocytic ehrlichiosis agent.." Journal of clinical microbiology. Vol. 36, no. 11. (January 1998.): 3278-84.

Barlough, J, E; Reubel, G, H; Madigan, J, E; Vredevoe, L, K; Miller, P, E; Rikihisa, Y. "Detection of Ehrlichia risticii, the agent of Potomac horse fever, in freshwater stream snails (Pleuroceridae: Juga spp.) from northern California.." Applied and environmental microbiology. Vol. 64, no. 8. (January 1998.): 2888-93.

Lee, E, H; Rikihisa, Y. "Protein kinase A-mediated inhibition of gamma interferon-induced tyrosine phosphorylation of Janus kinases and latent cytoplasmic transcription factors in human monocytes by Ehrlichia chaffeensis.." Infection and immunity. Vol. 66, no. 6. (January 1998.): 2514-20.

Horowitz, H, W; Aguero-Rosenfeld, M, E; McKenna, D, F; Holmgren, D; Hsieh, T, C; Varde, S, A; Dumler, S, J; Wu, J, M; Schwartz, I; Rikihisa, Y; Wormser, G P. "Clinical and laboratory spectrum of culture-proven human granulocytic ehrlichiosis: comparison with culture-negative cases.." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. Vol. 27, no. 5. (January 1998.): 1314-7.

Zhang, Y; Ohashi, N; Rikihisa, Y. "Cloning of the heat shock protein 70 (HSP70) gene of Ehrlichia sennetsu and differential expression of HSP70 and HSP60 mRNA after temperature upshift.." Infection and immunity. Vol. 66, no. 7. (January 1998.): 3106-12.

Ohashi, N; Zhi, N; Zhang, Y; Rikihisa, Y. "Immunodominant major outer membrane proteins of Ehrlichia chaffeensis are encoded by a polymorphic multigene family.." Infection and immunity. Vol. 66, no. 1. (January 1998.): 132-9.

Ohashi, N; Unver, A; Zhi, N; Rikihisa, Y. "Cloning and characterization of multigenes encoding the immunodominant 30-kilodalton major outer membrane proteins of Ehrlichia canis and application of the recombinant protein for serodiagnosis.." Journal of clinical microbiology. Vol. 36, no. 9. (January 1998.): 2671-80.

Rikihisa, Y. "Clinical and biological aspects of infection caused by Ehrlichia chaffeensis.." Microbes and infection / Institut Pasteur. Vol. 1, no. 5. (January 1999.): 367-76.

Kawahara, M; Ito, T; Suto, C; Shibata, S; Rikihisa, Y; Hata, K; Hirai, K. "Comparison of Ehrlichia muris strains isolated from wild mice and ticks and serologic survey of humans and animals with E. muris as antigen.." Journal of clinical microbiology. Vol. 37, no. 4. (January 1999.): 1123-9.

Barnewall, R, E; Ohashi, N; Rikihisa, Y. "Ehrlichia chaffeensis and E. sennetsu, but not the human granulocytic ehrlichiosis agent, colocalize with transferrin receptor and up-regulate transferrin receptor mRNA by activating iron-responsive protein 1.." Infection and immunity. Vol. 67, no. 5. (January 1999.): 2258-65.

Zhi, N; Ohashi, N; Rikihisa, Y. "Multiple p44 genes encoding major outer membrane proteins are expressed in the human granulocytic ehrlichiosis agent.." The Journal of biological chemistry. Vol. 274, no. 25. (January 1999.): 17828-36.

Unver, A; Rikihisa, Y; Ohashi, N; Cullman, L, C; Buller, R; Storch, G A. "Western and dot blotting analyses of Ehrlichia chaffeensis indirect fluorescent-antibody assay-positive and -negative human sera by using native and recombinant E. chaffeensis and E. canis antigens.." Journal of clinical microbiology. Vol. 37, no. 12. (January 1999.): 3888-95.

Mott, J; Barnewall, R, E; Rikihisa, Y. "Human granulocytic ehrlichiosis agent and Ehrlichia chaffeensis reside in different cytoplasmic compartments in HL-60 cells.." Infection and immunity. Vol. 67, no. 3. (January 1999.): 1368-78.

Kanter, M; Mott, J; Ohashi, N; Fried, B; Reed, S; Lin, Y, C; Rikihisa, Y. "Analysis of 16S rRNA and 51-kilodalton antigen gene and transmission in mice of Ehrlichia risticii in virgulate trematodes from Elimia livescens snails in Ohio.." Journal of clinical microbiology. Vol. 38, no. 9. (January 2000.): 3349-58.

Rikihisa, Y. "Diagnosis of emerging ehrlichial diseases of dogs, horses, and humans.." Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. Vol. 14, no. 3. (January 2000.): 250-1.

Rikihisa, Y. "Ehrlichial strategy for survival and proliferation in leukocytes.." Sub-cellular biochemistry. Vol. 33, (January 2000.): 517-38.

Yoshiie, K; Kim, H, Y; Mott, J; Rikihisa, Y. "Intracellular infection by the human granulocytic ehrlichiosis agent inhibits human neutrophil apoptosis.." Infection and immunity. Vol. 68, no. 3. (January 2000.): 1125-33.

Tajima, T; Zhi, N; Lin, Q; Rikihisa, Y; Horowitz, H, W; Ralfalli, J; Wormser, G, P; Hechemy, K E. "Comparison of two recombinant major outer membrane proteins of the human granulocytic ehrlichiosis agent for use in an enzyme-linked immunosorbent assay.." Clinical and diagnostic laboratory immunology. Vol. 7, no. 4. (January 2000.): 652-7.

Sumner, J, W; Storch, G, A; Buller, R, S; Liddell, A, M; Stockham, S, L; Rikihisa, Y; Messenger, S; Paddock, C D. "PCR amplification and phylogenetic analysis of groESL operon sequences from Ehrlichia ewingii and Ehrlichia muris.." Journal of clinical microbiology. Vol. 38, no. 7. (January 2000.): 2746-9.

Shibata, S; Kawahara, M; Rikihisa, Y; Fujita, H; Watanabe, Y; Suto, C; Ito, T. "New Ehrlichia species closely related to Ehrlichia chaffeensis isolated from Ixodes ovatus ticks in Japan.." Journal of clinical microbiology. Vol. 38, no. 4. (January 2000.): 1331-8.

Mott, J; Rikihisa, Y. "Human granulocytic ehrlichiosis agent inhibits superoxide anion generation by human neutrophils.." Infection and immunity. Vol. 68, no. 12. (January 2000.): 6697-703.

Kim, H, Y; Rikihisa, Y. "Expression of interleukin-1beta, tumor necrosis factor alpha, and interleukin-6 in human peripheral blood leukocytes exposed to human granulocytic ehrlichiosis agent or recombinant major surface protein P44.." Infection and immunity. Vol. 68, no. 6. (January 2000.): 3394-402.

Okada, H; Tajima, T; Kawahara, M; Rikihisa, Y. "Ehrlichial proliferation and acute hepatocellular necrosis in immunocompetent mice experimentally infected with the HF strain of Ehrlichia, closely related to Ehrlichia chaffeensis.." Journal of comparative pathology. Vol. 124, no. 2-3. (January 2001.): 165-71.

Ohashi, N; Rikihisa, Y; Unver, A. "Analysis of transcriptionally active gene clusters of major outer membrane protein multigene family in Ehrlichia canis and E. chaffeensis.." Infection and immunity. Vol. 69, no. 4. (January 2001.): 2083-91.

Dumler, J, S; Barbet, A, F; Bekker, C, P; Dasch, G, A; Palmer, G, H; Ray, S, C; Rikihisa, Y; Rurangirwa, F R. "Reorganization of genera in the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales: unification of some species of Ehrlichia with Anaplasma, Cowdria with Ehrlichia and Ehrlichia with Neorickettsia, descriptions of six new." International journal of systematic and evolutionary microbiology. Vol. 51, no. Pt 6. (January 2001.): 2145-65.

Unver, A; Perez, M; Orellana, N; Huang, H; Rikihisa, Y. "Molecular and antigenic comparison of Ehrlichia canis isolates from dogs, ticks, and a human in Venezuela.." Journal of clinical microbiology. Vol. 39, no. 8. (January 2001.): 2788-93.

Unver, A; Ohashi, N; Tajima, T; Stich, R, W; Grover, D; Rikihisa, Y. "Transcriptional analysis of p30 major outer membrane multigene family of Ehrlichia canis in dogs, ticks, and cell culture at different temperatures.." Infection and immunity. Vol. 69, no. 10. (January 2001.): 6172-8.

Unver, A; Felek, S; Paddock, C, D; Zhi, N; Horowitz, H, W; Wormser, G, P; Cullman, L, C; Rikihisa, Y. "Western blot analysis of sera reactive to human monocytic ehrlichiosis and human granulocytic ehrlichiosis agents.." Journal of clinical microbiology. Vol. 39, no. 11. (January 2001.): 3982-6.

Neimark, H; Johansson, K, E; Rikihisa, Y; Tully, J G. "Proposal to transfer some members of the genera Haemobartonella and Eperythrozoon to the genus Mycoplasma with descriptions of 'Candidatus Mycoplasma haemofelis', 'Candidatus Mycoplasma haemomuris', 'Candidatus Mycoplasma haemosuis' and." International journal of systematic and evolutionary microbiology. Vol. 51, no. Pt 3. (January 2001.): 891-9.

Felek, S; Unver, A; Stich, R, W; Rikihisa, Y. "Sensitive detection of Ehrlichia chaffeensis in cell culture, blood, and tick specimens by reverse transcription-PCR.." Journal of clinical microbiology. Vol. 39, no. 2. (January 2001.): 460-3.

Stich, Roger, W; Rikihisa, Yasuko; Ewing, S, A; Needham, Glen, R; Grover, Debra, L; Jittapalapong, Sathaporn. "Detection of Ehrlichia canis in canine carrier blood and in individual experimentally infected ticks with a p30-based PCR assay.." Journal of clinical microbiology. Vol. 40, no. 2. (January 2002.): 540-6.

Lin, Mingqun; Zhu, Michael, ; XRikihisa, Yasuko. "Rapid activation of protein tyrosine kinase and phospholipase C-gamma2 and increase in cytosolic free calcium are required by Ehrlichia chaffeensis for internalization and growth in THP-1 cells.." Infection and immunity. Vol. 70, no. 2. (January 2002.): 889-98.

Mott, Jason; Rikihisa, Yasuko; Tsunawaki, Shohko. "Effects of Anaplasma phagocytophila on NADPH oxidase components in human neutrophils and HL-60 cells.." Infection and immunity. Vol. 70, no. 3. (January 2002.): 1359-66.

Mott, Jason; Muramatsu, Yasukazu; Seaton, Elizabeth; Martin, Carol; Reed, Stephen; Rikihisa, Yasuko. "Molecular analysis of Neorickettsia risticii in adult aquatic insects in Pennsylvania, in horses infected by ingestion of insects, and isolated in cell culture.." Journal of clinical microbiology. Vol. 40, no. 2. (January 2002.): 690-3.

Lin, Quan; Zhi, Ning; Ohashi, Norio; Horowitz, Harold, W; Aguero-Rosenfeld, Maria, E; Raffalli, John; Wormser, Gary, P; Rikihisa, Yasuko. "Analysis of sequences and loci of p44 homologs expressed by Anaplasma phagocytophila in acutely infected patients.." Journal of clinical microbiology. Vol. 40, no. 8. (January 2002.): 2981-8.

Liddell, Allison, M; Sumner, John, W; Paddock, Christopher, D; Rikihisa, Yasuko; Unver, Ahmet; Buller, Richard, S; Storch, Gregory A. "Reinfection with Ehrlichia chaffeensis in a liver transplant recipient.." Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. Vol. 34, no. 12. (January 2002.): 1644-7.

Harasawa, Ryo; Kawahara, Makoto; Rikihisa, Yasuko. "Characteristics of the 16S-23S rRNA intergenic spacer region of Mycoplasma haemomuris, previously classified as 'Haemobartonella muris'.." The Journal of veterinary medical science / the Japanese Society of Veterinary Science. Vol. 64, no. 12. (January 2002.): 1161-4.

Kim, Hyung-Yong; Rikihisa, Yasuko. "Roles of p38 mitogen-activated protein kinase, NF-kappaB, and protein kinase C in proinflammatory cytokine mRNA expression by human peripheral blood leukocytes, monocytes, and neutrophils in response to Anaplasma phagocytophila.." Infection and immunity. Vol. 70, no. 8. (January 2002.): 4132-41.

Kim, Hyung-Yong; Mott, Jason; Zhi, Ning; Tajima, Tomoko; Rikihisa, Yasuko. "Cytokine gene expression by peripheral blood leukocytes in horses experimentally infected with Anaplasma phagocytophila.." Clinical and diagnostic laboratory immunology. Vol. 9, no. 5. (January 2002.): 1079-84.

Ohashi, Norio; Zhi, Ning; Lin, Quan; Rikihisa, Yasuko. "Characterization and transcriptional analysis of gene clusters for a type IV secretion machinery in human granulocytic and monocytic ehrlichiosis agents.." Infection and immunity. Vol. 70, no. 4. (January 2002.): 2128-38.

Zhi, Ning; Ohashi, Norio; Tajima, Tomoko; Mott, Jason; Stich, Roger, W; Grover, Debra; Telford, Sam R 3rd; Lin, Quan; Rikihisa, Yasuko. "Transcript heterogeneity of the p44 multigene family in a human granulocytic ehrlichiosis agent transmitted by ticks.." Infection and immunity. Vol. 70, no. 3. (January 2002.): 1175-84.

Zhi, Ning; Ohashi, Norio; Rikihisa, Yasuko. "Activation of a p44 pseudogene in Anaplasma phagocytophila by bacterial RNA splicing: a novel mechanism for post-transcriptional regulation of a multigene family encoding immunodominant major outer membrane proteins.." Molecular microbiology. Vol. 46, no. 1. (January 2002.): 135-45.

Zhang, Chunbin; Rikihisa, Yasuko. "Evaluation of sensitivity and specificity of a Mycoplasma haemomuris-specific polymerase chain reaction test.." Comparative medicine. Vol. 52, no. 4. (January 2002.): 313-5.

Unver, Ahmet; Rikihisa, Yasuko; Stich, Roger, W; Ohashi, Norio; Felek, Suleyman. "The omp-1 major outer membrane multigene family of Ehrlichia chaffeensis is differentially expressed in canine and tick hosts.." Infection and immunity. Vol. 70, no. 8. (January 2002.): 4701-4.

Neimark, Harold; Johansson, Karl-Erik; Rikihisa, Yasuko; Tully, Joseph G. "Revision of haemotrophic Mycoplasma species names.." International journal of systematic and evolutionary microbiology. Vol. 52, no. Pt 2. (January 2002.): 683-.

Lin, Mingqun; Rikihisa, Yasuko. "Obligatory intracellular parasitism by Ehrlichia chaffeensis and Anaplasma phagocytophilum involves caveolae and glycosylphosphatidylinositol-anchored proteins.." Cellular microbiology. Vol. 5, no. 11. (January 2003.): 809-20.

Lin, Mingqun; Rikihisa, Yasuko. "Ehrlichia chaffeensis and Anaplasma phagocytophilum lack genes for lipid A biosynthesis and incorporate cholesterol for their survival.." Infection and immunity. Vol. 71, no. 9. (January 2003.): 5324-31.

Okada, H; Usuda, H; Tajima, T; Kawahara, M; Yoshino, T; Rikihisa, Y. "Distribution of ehrlichiae in tissues as determined by in-situ hybridization.." Journal of comparative pathology. Vol. 128, no. 2-3. (January 2003.): 182-7.

Lin, Quan; Rikihisa, Yasuko; Ohashi, Norio; Zhi, Ning. "Mechanisms of variable p44 expression by Anaplasma phagocytophilum.." Infection and immunity. Vol. 71, no. 10. (January 2003.): 5650-61.

Felek, Suleyman; Huang, Haibin; Rikihisa, Yasuko. "Sequence and expression analysis of virB9 of the type IV secretion system of Ehrlichia canis strains in ticks, dogs, and cultured cells.." Infection and immunity. Vol. 71, no. 10. (January 2003.): 6063-7.

Felek, Suleyman; Greene, Russell; Rikihisa, Yasuko. "Transcriptional analysis of p30 major outer membrane protein genes of Ehrlichia canis in naturally infected ticks and sequence analysis of p30-10 of E canis from diverse geographic regions.." Journal of clinical microbiology. Vol. 41, no. 2. (January 2003.): 886-8.

Unver, Ahmet; Rikihisa, Yauko; Kawahara, Makoto; Yamamoto, Shizuo. "Analysis of 16S rRNA gene sequences of Ehrlichia canis, Anaplasma platys, and Wolbachia species from canine blood in Japan.." Annals of the New York Academy of Sciences. Vol. 990, (January 2003.): 692-8.

Rikihisa, Yasuko; Zhang, Chunbin; Christensen, Bruce M. "Molecular characterization of Aegyptianella pullorum (Rickettsiales, Anaplasmataceae).." Journal of clinical microbiology. Vol. 41, no. 11. (January 2003.): 5294-7.

Rikihisa, Yasuko. "Mechanisms to create a safe haven by members of the family Anaplasmataceae.." Annals of the New York Academy of Sciences. Vol. 990, (January 2003.): 548-55.

Wagner, Elizabeth, R; Bremer, William, G; Rikihisa, Yasuko; Ewing, S, A; Needham, Glen, R; Unver, Ahmet; Wang, Xueqi; Stich, Roger W. "Development of a p28-based PCR assay for Ehrlichia chaffeensis.." Molecular and cellular probes. Vol. 18, no. 2. (January 2004.): 111-6.

Lin, Mingqun; Rikihisa, Yasuko. "Ehrlichia chaffeensis downregulates surface Toll-like receptors 2/4, CD14 and transcription factors PU.1 and inhibits lipopolysaccharide activation of NF-kappa B, ERK 1/2 and p38 MAPK in host monocytes.." Cellular microbiology. Vol. 6, no. 2. (January 2004.): 175-86.

Felek, Suleyman; Telford, Sam 3rd; Falco, Richard, C; Rikihisa, Yasuko. "Sequence analysis of p44 homologs expressed by Anaplasma phagocytophilum in infected ticks feeding on naive hosts and in mice infected by tick attachment.." Infection and immunity. Vol. 72, no. 2. (January 2004.): 659-66.

Rikihisa, Yasuko; Zhang, Chunbin; Kanter, Manuel; Cheng, Zhihui; Ohashi, Norio; Fukuda, Takeo. "Analysis of p51, groESL, and the major antigen P51 in various species of Neorickettsia, an obligatory intracellular bacterium that infects trematodes and mammals.." Journal of clinical microbiology. Vol. 42, no. 8. (January 2004.): 3823-6.

Kawahara, Makoto; Rikihisa, Yasuko; Isogai, Emiko; Takahashi, Mamoru; Misumi, Hitoko; Suto, Chiharu; Shibata, Shinichiro; Zhang, Chunbin; Tsuji, Masayoshi. "Ultrastructure and phylogenetic analysis of 'Candidatus Neoehrlichia mikurensis' in the family Anaplasmataceae, isolated from wild rats and found in Ixodes ovatus ticks.." International journal of systematic and evolutionary microbiology. Vol. 54, no. Pt 5. (January 2004.): 1837-43.

Wang, Xueqi; Rikihisa, Yasuko; Lai, Tzung-Hui; Kumagai, Yumi; Zhi, Ning; Reed, Stephen M. "Rapid sequential changeover of expressed p44 genes during the acute phase of Anaplasma phagocytophilum infection in horses.." Infection and immunity. Vol. 72, no. 12. (January 2004.): 6852-9.

Lin, Quan; Rikihisa, Yasuko; Massung, Robert, F; Woldehiwet, Zerai; Falco, Richard C. "Polymorphism and transcription at the p44-1/p44-18 genomic locus in Anaplasma phagocytophilum strains from diverse geographic regions.." Infection and immunity. Vol. 72, no. 10. (January 2004.): 5574-81.

Lin, Quan; Rikihisa, Yasuko; Felek, Suleyman; Wang, Xueqi; Massung, Robert, F; Woldehiwet, Zerai. "Anaplasma phagocytophilum has a functional msp2 gene that is distinct from p44.." Infection and immunity. Vol. 72, no. 7. (January 2004.): 3883-9.

Zhang, Chunbin; Rikihisa, Yasuko. "Proposal to transfer 'Aegyptianella ranarum', an intracellular bacterium of frog red blood cells, to the family Flavobacteriaceae as 'Candidatus Hemobacterium ranarum' comb. nov.." Environmental microbiology. Vol. 6, no. 6. (January 2004.): 568-73.

Bremer, William, G; Schaefer, John, J; Wagner, Elizabeth, R; Ewing, S, A; Rikihisa, Yasuko; Needham, Glen, R; Jittapalapong, Sathaporn; Moore, Debra, L; Stich, Roger W. "Transstadial and intrastadial experimental transmission of Ehrlichia canis by male Rhipicephalus sanguineus.." Veterinary parasitology. Vol. 131, no. 1-2. (January 2005.): 95-105.

Ge, Yan; Yoshiie, Kiyotaka; Kuribayashi, Futoshi; Lin, Mingqun; Rikihisa, Yasuko. "Anaplasma phagocytophilum inhibits human neutrophil apoptosis via upregulation of bfl-1, maintenance of mitochondrial membrane potential and prevention of caspase 3 activation.." Cellular microbiology. Vol. 7, no. 1. (January 2005.): 29-38.

Lin, Quan; Rikihisa, Yasuko. "Establishment of cloned Anaplasma phagocytophilum and analysis of p44 gene conversion within an infected horse and infected SCID mice.." Infection and immunity. Vol. 73, no. 8. (January 2005.): 5106-14.

Tajima, Tomoko; Rikihisa, Yasuko. "Cytokine responses in dogs infected with Ehrlichia canis Oklahoma strain.." Annals of the New York Academy of Sciences. Vol. 1063, (January 2005.): 429-32.

Gibson, Kathryn, E; Rikihisa, Yasuko; Zhang, Chunbin; Martin, Carole. "Neorickettsia risticii is vertically transmitted in the trematode Acanthatrium oregonense and horizontally transmitted to bats.." Environmental microbiology. Vol. 7, no. 2. (January 2005.): 203-12.

Unver, Ahmet; Rikihisa, Yasuko; Borku, Kazim; Ozkanlar, Yunusemre; Hanedan, Basak. "Molecular detection and characterization of Ehrlichia canis from dogs in Turkey.." Berliner und Munchener tierarztliche Wochenschrift. Vol. 118, no. 7-8. (January 2005.): 300-4.

Hotopp, Julie C Dunning; Lin, Mingqun; Madupu, Ramana; Crabtree, Jonathan; Angiuoli, Samuel, V; Eisen, Jonathan; Seshadri, Rekha; Ren, Qinghu; Wu, Martin; Utterback, Teresa, R; Smith, Shannon; Lewis, Matthew; Khouri, Hoda; Zhang, Chunbin; Niu, Hua; Lin, Quan; Ohashi, Norio; Zhi, Ning; Nelson, William; Brinkac, Lauren, M; et al.. "Comparative genomics of emerging human ehrlichiosis agents.." PLoS genetics. Vol. 2, no. 2. (January 2006.): e21-.

Kumagai, Yumi; Cheng, Zhihui; Lin, Mingqun; Rikihisa, Yasuko. "Biochemical activities of three pairs of Ehrlichia chaffeensis two-component regulatory system proteins involved in inhibition of lysosomal fusion.." Infection and immunity. Vol. 74, no. 9. (January 2006.): 5014-22.

Wang, Xueqi; Kikuchi, Takane; Rikihisa, Yasuko. "Two monoclonal antibodies with defined epitopes of P44 major surface proteins neutralize Anaplasma phagocytophilum by distinct mechanisms.." Infection and immunity. Vol. 74, no. 3. (January 2006.): 1873-82.

Niu, Hua; Rikihisa, Yasuko; Yamaguchi, Mamoru; Ohashi, Norio. "Differential expression of VirB9 and VirB6 during the life cycle of Anaplasma phagocytophilum in human leucocytes is associated with differential binding and avoidance of lysosome pathway.." Cellular microbiology. Vol. 8, no. 3. (January 2006.): 523-34.

Ge, Yan; Rikihisa, Yasuko. "Anaplasma phagocytophilum delays spontaneous human neutrophil apoptosis by modulation of multiple apoptotic pathways.." Cellular microbiology. Vol. 8, no. 9. (January 2006.): 1406-16.

Cheng, Zhihui; Kumagai, Yumi; Lin, Mingqun; Zhang, Chunbin; Rikihisa, Yasuko. "Intra-leukocyte expression of two-component systems in Ehrlichia chaffeensis and Anaplasma phagocytophilum and effects of the histidine kinase inhibitor closantel.." Cellular microbiology. Vol. 8, no. 8. (January 2006.): 1241-52.

Unver, Ahmet; Huang, Haibin; Rikihisa, Yasuko. "Cytokine gene expression by peripheral blood leukocytes in dogs experimentally infected with a new virulent strain of Ehrlichia canis.." Annals of the New York Academy of Sciences. Vol. 1078, (January 2006.): 482-6.

Rikihisa, Yasuko. "New findings on members of the family Anaplasmataceae of veterinary importance.." Annals of the New York Academy of Sciences. Vol. 1078, (January 2006.): 438-45.

Rikihisa, Yasuko. "Ehrlichia subversion of host innate responses.." Current opinion in microbiology. Vol. 9, no. 1. (January 2006.): 95-101.

Perez, Miriam; Bodor, Mairim; Zhang, Chunbin; Xiong, Qingmin; Rikihisa, Yasuko. "Human infection with Ehrlichia canis accompanied by clinical signs in Venezuela.." Annals of the New York Academy of Sciences. Vol. 1078, (January 2006.): 110-7.

Lin, Quan; Zhang, Chunbin; Rikihisa, Yasuko. "Analysis of involvement of the RecF pathway in p44 recombination in Anaplasma phagocytophilum and in Escherichia coli by using a plasmid carrying the p44 expression and p44 donor loci.." Infection and immunity. Vol. 74, no. 4. (January 2006.): 2052-62.

Kawahara, Makoto; Rikihisa, Yasuko; Lin, Quan; Isogai, Emiko; Tahara, Kenji; Itagaki, Asao; Hiramitsu, Yoshimichi; Tajima, Tomoko. "Novel genetic variants of Anaplasma phagocytophilum, Anaplasma bovis, Anaplasma centrale, and a novel Ehrlichia sp. in wild deer and ticks on two major islands in Japan.." Applied and environmental microbiology. Vol. 72, no. 2. (January 2006.): 1102-9.

Lin, Mingqun; den Dulk-Ras, Amke; Hooykaas, Paul J, J; Rikihisa, Yasuko. "Anaplasma phagocytophilum AnkA secreted by type IV secretion system is tyrosine phosphorylated by Abl-1 to facilitate infection.." Cellular microbiology. Vol. 9, no. 11. (January 2007.): -.

Wang, Xueqi; Kikuchi, Takane; Rikihisa, Yasuko. "Proteomic identification of a novel Anaplasma phagocytophilum DNA binding protein that regulates a putative transcription factor.." Journal of bacteriology. Vol. 189, no. 13. (January 2007.): 4880-6.

Wang, Xueqi; Cheng, Zhihui; Zhang, Chunbin; Kikuchi, Takane; Rikihisa, Yasuko. "Anaplasma phagocytophilum p44 mRNA expression is differentially regulated in mammalian and tick host cells: involvement of the DNA binding protein ApxR.." Journal of bacteriology. Vol. 189, no. 23. (January 2007.): -.

Schaefer, JJ; Kahn, J; Needham, GR; Rikihisa, Y; Ewing, SA; Stich, RW. "Antibiotic clearance of Ehrlichia canis from dogs infected by intravenous inoculation of carrier blood." Antimicrob. Agents Chemother. (January 2007.): -.

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Ge, Yan; Rikihisa, Yasuko. "Identification of novel surface proteins of Anaplasma phagocytophilum by affinity purification and proteomics.." Journal of bacteriology. Vol. 189, no. 21. (January 2007.): -.

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Delos Santos, JR; Boughan, K; Bremer, WG; Rizzo, B; Schaefer, JJ; Rikihisa, Y; Needham, GR; Capitini, LA; Anderson, DE; Oglesbee, M; Ewing, SA; Stich, RW. "Experimental infection of dairy calves with Ehrlichia chaffeensis." J Med Microbiol. (January 2007.): -.

Xiong, Qingming; Wang, Xueqi; Rikihisa, Yasuko. "High-cholesterol diet facilitates Anaplasma phagocytophilum infection and up-regulates macrophage inflammatory protein-2 and CXCR2 expression in apolipoprotein E-deficient mice.." The Journal of infectious diseases. Vol. 195, no. 10. (January 2007.): 1497-503.

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