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William Lafuse, PhD


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460 W 12th Ave
Columbus, OH 43210

Phone: (614) 366-1751

Email: lafuse.1@osu.edu

 

Current OSU Appointment

Professor, SBS-Microbial Infectn/Immunity

 

Chapters in Books

David, C.S., Beisel, K.W., Krco, C.J., and Lafuse, W.P.. "Genetic organization, tissue expression and functional role of murine Ia antigens." In Current Trends in Histocompatibility. Edited by R.A. Reisfeld and S. Ferrone. -. New York, NY: Plenum Press, January 1981.

David, C.S., Lafuse, W.P. and Yokota, S.. "Hybrid antigens. Identification characterization and role in immune response." In Immunology of Major Histocompatibility System. Edited by M. Zaleski and J.F. Mohn, S. Karger. 28-36. Basel, January 1981.

Lafuse, W.P. and David, C.S.. "Murine Ia antigens: Studies using hybrid and mutant mice." In H-2-Ia and HLA-Dr Antigens. Vol. 1 Mice. Edited by S. Ferrone and C.S. David. 105-142. CRC Press, January 1982.

David, C.S. and Lafuse, W.P.. "Ia genes, gene products and determinants." In Ir Genes, Past, Present and Future. Edited by D.W. Pierce, S.E. Cullen, J.A. Kapp, B.D. Schwartz and D.C. Shreffler. 3-12. Clifton, NJ: Humana Press, January 1983.

Singh, S., Lafuse, W.P., McKean, D.J. and David, C.S.. "Structural characterization of I-A subsets using monoclonal antibodies." In Ir Genes, Past, Present and Future. Edited by C.W. Pierce, S.E. Cullen, J.A. Kapp, B.D. Schwartz, D.C. Shreffler. -. Clifton, NJ: Humana Press, January 1983.

Lafuse, W.P., Pierres, M. and David, C.S.. "Isolation and analysis of subpopulations of I-Ab molecules with monoclonal antibodies." In Ir Genes, Past, Present and Future. Edited by C.W. Pierce, S.E. Cullen, J.A. Kapp, B.D. Schwartz, D.C. Shreffler. 4549-. Clifton, NJ: Humana Press, January 1983.

Lafuse, W.P. and David, C.S.. "Recombination sites within the I region of the mouse H-2 complex.." In H-2 antigens, genes, molecules, function. Edited by C.S. David. 41-. New York, NY: Plenum Press, January 1988.

 

Degrees

1973 B.S., Purdue University

1978 Ph.D., Johns Hopkins University

 

Editorial Activities

1987 - present Journal of Immunology and Leukocyte Biology
1990 - present Journal of Leukocyte Biology
1990 - present Brain, Behavior, and Immunity
1995 - present Journal of Experimental Medicine
2010 - present Blood
 

Honors

1979 - 1980 American Cancer Postdoctoral Fellowship.
1999 Simson Faculty Research Award.
 

Journal Articles

Lafuse, W., Mereulo, D. and Edidin, M.. "The genetic control of liver cAMP levels in mice." Immunogenetics. Vol. 9, no. 49. (January 1979.): -.

Lafuse, W; Edidin, M. "Influence of the mouse major histocompatibility complex, H-2, on liver adenylate cyclase activity and on glucagon binding to liver cell membranes.." Biochemistry. Vol. 19, no. 1. (January 1980.): 49-54.

Lafuse, W.P., Neely, B.C. and David, C.S.. "Biochemical studies of mouse Ia molecules with xenoantisera. I. Identification of a second Ia molecule (I-E) in H-2s haplotype." Immunogenetics. Vol. 10, no. 311. (January 1980.): -.

Lafuse, W, P; Yokota, S; David, C S. "Hybrid Ia antigens: genetic, serologic, and biochemical analyses.." Journal of supramolecular structure. Vol. 14, no. 1. (January 1980.): 97-106.

Lafuse, W, P; McCormick, J, F; David, C S. "Serological and biochemical identification of hybrid Ia antigens.." The Journal of experimental medicine. Vol. 151, no. 3. (January 1980.): 709-15.

Lafuse, W, P; McCormick, J, F; David, C S. "Lack of gene complementation prevents expression of I-Ek in recombinant A.TFR5.." J Immunol. Vol. 124, no. 5. (January 1980.): 2511-3.

Lafuse, W, P; McCormick, J, F; Corser, P, S; David, C S. "Gene complementations to generate Ia antigens (Ia.23) on hybrid molecules.." Transplantation. Vol. 30, no. 5. (January 1980.): 341-6.

Beisel, K, W; Lafuse, W, P; Stimpfling, J, H; David, C S. "Description of the H-2K-, H-2I-, and H-2D-gene products of the H-2 haplotype.." Immunogenetics. Vol. 11, no. 4. (January 1980.): 407-11.

Long, P, M; Lafuse, W, P; David, C S. "Serologic and biochemical identification of minor histocompatibility (H-4) antigens.." J Immunol. Vol. 127, no. 3. (January 1981.): 825-8.

Krco, C, J; Challacombe, S, J; Lafuse, W, P; David, C, S; Tomasi, T B Jr. "Expression of Ia antigens by mouse Peyer's patch cells.." Cellular immunology. Vol. 57, no. 2. (January 1981.): 420-6.

Beisel, K, W; Lafuse, W, P; Stimpfling, J, H; David, C S. "Identification of private H-2 and Ia specificities of H-2r haplotype.." Immunogenetics. Vol. 12, no. 1-2. (January 1981.): 191-7.

Yokota, S; Lafuse, W, P; McCormick, J, F; David, C S. "Detection of hybrid (combinatorial) Ia antigens using parent anti-F1 sera.." J Immunol. Vol. 126, no. 1. (January 1981.): 371-4.

Lafuse, W.P. and David, C.S. Hybrid. "Ia antigens mediate histocompatibility auto and alloreactivity, and immune recognition." Transplantation Proc. Vol. 13, no. 1346. (January 1981.): -.

Lafuse, W, P; Yokota, S; David, C S. "Gene complementations generate hybrid Ia specificities involved in immune response.." Transplantation proceedings. Vol. 13, no. 1 Pt 2. (January 1981.): 1017-9.

Lafuse, W, P; McCormick, J, F; Melvold, R, W; David, C S. "Serological and biochemical analysis of Ia molecules in the I-A mutant B6.C-H-2.." Transplantation. Vol. 31, no. 6. (January 1981.): 434-8.

Lafuse, W, P; McCormick, J, F; Corser, P, S; David, C S. "Hybrid (combinatorial) Ia specificities: gene complementations to generate Ia.22.." Immunogenetics. Vol. 13, no. 1-2. (January 1981.): 115-25.

Lafuse, W, P; Hendrickson, H, I; Corser, P, S; David, C S. "Serologic and biochemical analyses of a variant Ae (E beta) ia polypeptide chain in D2.gD (H-2g2).." J Immunol. Vol. 127, no. 2. (January 1981.): 811-3.

Lafuse, W, P; David, C S. "Hybrid (combinatorial) Ia antigens mediate histoincompatibility, auto and alloreactivity, and immune recognition.." Transplantation proceedings. Vol. 13, no. 4. (January 1981.): 1846-9.

Pierres, M; Lafuse, W, P; Dosseto, M; Devaux, C; Birnbaum, D, Z; David, C S. "Molecular specificity of a monoclonal anti-Ik alloantibody identifying a highly conserved determinant on mouse I-A, I-E and human DR antigens.." Tissue antigens. Vol. 20, no. 3. (January 1982.): 208-20.

David, C, S; Lafuse, W, P; Pierres, M. "Biochemical evidence for multiple Ia molecules.." Advances in experimental medicine and biology. Vol. 155, (January 1982.): 569-77.

Lafuse, W, P; Corser, P, S; David, C S. "Biochemical evidence for multiple I-E Ia molecules.." Immunogenetics. Vol. 15, no. 4. (January 1982.): 365-75.

Lafuse, W, P; Pierres, M; David, C S. "Cross-reactions of anti-I-Ek monoclonal antibodies with subsets of I-Ab molecules.." Transplantation. Vol. 35, no. 1. (January 1983.): 49-55.

Lafuse, W, P; David, C S. "Ia antigens: genes, molecules and function.." Transplantation. Vol. 38, no. 5. (January 1984.): 443-53.

Savariayan, S., Lafuse, W.P., and David, C.S.. "Recombination between H-2D and H-2L Genes: Identification, Characterization and Gene Order." Transplant Proc. Vol. 18, no. 702. (January 1985.): -.

Wooley, P, H; Luthra, H, S; Lafuse, W, P; Huse, A; Stuart, J, M; David, C S. "Type II collagen-induced arthritis in mice. III. Suppression of arthritis by using monoclonal and polyclonal anti-Ia antisera.." J Immunol. Vol. 134, no. 4. (January 1985.): 2366-74.

Rodriguez, M; Lafuse, W, P; Leibowitz, J; David, C S. "Partial suppression of Theiler's virus-induced demyelination in vivo by administration of monoclonal antibodies to immune-response gene products (Ia antigens).." Neurology. Vol. 36, no. 7. (January 1986.): 964-70.

Lafuse, W, P; Singh, S; Savarirayan, S; David, C S. "DNA restriction fragment analysis of E alpha genes in E-negative H-2 recombinant mouse strains.." Immunogenetics. Vol. 24, no. 1. (January 1986.): 68-70.

Lafuse, W, P; Pierres, M; David, C S. "Molecular heterogeneity of I-Ab molecules: analysis of I-Ab subsets with monoclonal antibodies.." Immunological investigations. Vol. 15, no. 8. (January 1986.): 735-48.

Lafuse, W, P; Berg, N; Savarirayan, S; David, C S. "Mapping of a second recombination hot spot within the I-E region of the mouse H-2 gene complex.." The Journal of experimental medicine. Vol. 163, no. 6. (January 1986.): 1518-28.

Lafuse, W, P; David, C S. "Recombination hot spots within the I region of the mouse H-2 complex map to the E beta and E alpha genes.." Immunogenetics. Vol. 24, no. 6. (January 1986.): 352-60.

David, C, S; McCormick, J, F; Lafuse, W, P; Hirose, S. "Serological confirmation in Ia mutant B6.C-H-2bm12 of gene conversion.." Transplantation. Vol. 42, no. 4. (January 1986.): 429-33.

Lafuse, W, P; Savarirayan, S; McCormick, J, F; David, C S. "Identification of I-E alpha genes in H-2 recombinant mouse strains by F1 complementation.." Transplantation. Vol. 43, no. 2. (January 1987.): 297-301.

Zwilling, B, S; Massie, M; Vespa, L; Kwasniewski, M; Nath, J; LaFuse, W. "Continuous expression of I-A by murine peritoneal macrophages is linked to the Bcg gene.." Current topics in microbiology and immunology. Vol. 137, (January 1988.): 316-24.

Nath, J; Lafuse, W; Zwilling, B S. "Regulation of class II MHC gene expression by macrophages from Bcgr and Bcgs mice.." Cellular immunology. Vol. 117, no. 1. (January 1988.): 127-35.

Lafuse, W, P; Lee, S, T; Castle, L; David, C S. "Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.." Immunogenetics. Vol. 30, no. 5. (January 1989.): 387-9.

Lafuse, W, P; Lee, S, T; David, C S. "Molecular analysis of two recombinant mouse strains with crossovers in the E alpha recombination hot spot.." Journal of immunogenetics. Vol. 17, no. 3. (January 1990.): 169-76.

Lafuse, W, P; Castle, L; David, C S. "Restriction fragment length polymorphism analysis of factor B and C2 genes in H-2 recombinant mouse strains.." Immunogenetics. Vol. 31, no. 4. (January 1990.): 275-7.

Glaser, R; Kennedy, S; Lafuse, W, P; Bonneau, R, H; Speicher, C; Hillhouse, J; Kiecolt-Glaser, J K. "Psychological stress-induced modulation of interleukin 2 receptor gene expression and interleukin 2 production in peripheral blood leukocytes.." Archives of general psychiatry. Vol. 47, no. 8. (January 1990.): 707-12.

Lafuse, W P. "Molecular biology of murine MHC class II genes.." Critical reviews in immunology. Vol. 11, no. 3-4. (January 1991.): 167-94.

Zwilling, B, S; Lafuse, W, P; Brown, D; Pearl, D. "Characterization of ACTH mediated suppression of MHC class II expression by murine peritoneal macrophages.." Journal of neuroimmunology. Vol. 39, no. 1-2. (January 1992.): 133-8.

Sant'Angelo, D, B; Lafuse, W, P; Passmore, H C. "Evidence that nucleotide sequence identity is a requirement for meiotic crossing over within the mouse Eb recombinational hot spot.." Genomics. Vol. 13, no. 4. (January 1992.): 1334-6.

Sabharwal, P; Glaser, R; Lafuse, W; Varma, S; Liu, Q; Arkins, S; Kooijman, R; Kutz, L; Kelley, K, W; Malarkey, W B. "Prolactin synthesized and secreted by human peripheral blood mononuclear cells: an autocrine growth factor for lymphoproliferation.." Proceedings of the National Academy of Sciences of the United States of America. Vol. 89, no. 16. (January 1992.): 7713-6.

Lafuse, W, P; Lanning, D; Spies, T; David, C S. "PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex.." Immunogenetics. Vol. 36, no. 2. (January 1992.): 110-6.

Lafuse, W, P; Brown, D; Zwilling, B S. "Assignment of the microtubule-associated protein 2 gene to mouse chromosome 1.." Mammalian genome : official journal of the International Mammalian Genome Society. Vol. 3, no. 1. (January 1992.): 48-51.

Lafuse, W, P; Zwilling, B S. "Localization of the inhibin beta B gene on mouse chromosome 1.." Mammalian genome : official journal of the International Mammalian Genome Society. Vol. 4, no. 7. (January 1993.): 399-400.

Glaser, R; Lafuse, W, P; Bonneau, R, H; Atkinson, C; Kiecolt-Glaser, J K. "Stress-associated modulation of proto-oncogene expression in human peripheral blood leukocytes.." Behavioral neuroscience. Vol. 107, no. 3. (January 1993.): 525-9.

Brown, D, H; LaFuse, W; Zwilling, B S. "Cytokine-mediated activation of macrophages from Mycobacterium bovis BCG-resistant and -susceptible mice: differential effects of corticosterone on antimycobacterial activity and expression of the Bcg gene (Candidate Nramp).." Infection and immunity. Vol. 63, no. 8. (January 1995.): 2983-8.

Lafuse, W.P., Castle, L., Brown, D. and Zwilling, B.S.. "Cloning and expression of a gene induced by IFN-? in mouse macrophages that encodes a protein with GTP binding motifs." J. Leukocyte Biol. Vol. 57, no. 477. (January 1995.): -.

Lafuse, W, P; Castle, L; Brown, D; Zwilling, B S. "The cytotoxic T lymphocyte gene FIBLP with homology to fibrinogen beta and gamma subunits is also induced in mouse macrophages by IFN-gamma.." Cellular immunology. Vol. 163, no. 2. (January 1995.): 187-90.

Lafuse, W, P; Brown, D; Castle, L; Zwilling, B S. "IFN-gamma increases cathepsin H mRNA levels in mouse macrophages.." Journal of leukocyte biology. Vol. 57, no. 4. (January 1995.): 663-9.

Lafuse, W, P; Brown, D; Castle, L; Zwilling, B S. "Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein.." Journal of leukocyte biology. Vol. 57, no. 3. (January 1995.): 477-83.

Miles, B, A; Lafuse, W, P; Zwilling, B S. "Binding of alpha-adrenergic receptors stimulates the anti-mycobacterial activity of murine peritoneal macrophages.." Journal of neuroimmunology. Vol. 71, no. 1-2. (January 1996.): 19-24.

Lanning, D; Lafuse, W P. "Localization of the casein kinase II beta-subunit gene within the mouse H-2 complex class III region and comparison of expression with Bat genes.." Mammalian genome : official journal of the International Mammalian Genome Society. Vol. 8, no. 7. (January 1997.): 519-21.

Brown, D, H; Lafuse, W, P; Zwilling, B S. "Stabilized expression of mRNA is associated with mycobacterial resistance controlled by Nramp1.." Infection and immunity. Vol. 65, no. 2. (January 1997.): 597-603.

Brown, D, H; Lafuse, W, P; Zwilling, B S. "Host resistance to mycobacteria is compromised by activation of the hypothalamic-pituitary-adrenal axis.." Annals of the New York Academy of Sciences. Vol. 840, (January 1998.): 773-86.

Zwilling, B, S; Kuhn, D, E; Wikoff, L; Brown, D; Lafuse, W. "Role of iron in Nramp1-mediated inhibition of mycobacterial growth.." Infection and immunity. Vol. 67, no. 3. (January 1999.): 1386-92.

Lanning, D; Lafuse, W P. "The mouse p52 subunit of the transcription/DNA repair factor TFIIH is located in the class III region of the H2 complex: cloning and sequence polymorphism.." Immunogenetics. Vol. 49, no. 6. (January 1999.): 498-504.

Hussain, S; Zwilling, B, S; Lafuse, W P. "Mycobacterium avium infection of mouse macrophages inhibits IFN-gamma Janus kinase-STAT signaling and gene induction by down-regulation of the IFN-gamma receptor.." J Immunol. Vol. 163, no. 4. (January 1999.): 2041-8.

Boomershine, C, S; Lafuse, W, P; Zwilling, B S. "Beta2-adrenergic receptor stimulation inhibits nitric oxide generation by Mycobacterium avium infected macrophages.." Journal of neuroimmunology. Vol. 101, no. 1. (January 1999.): 68-75.

Kuhn, D, E; Baker, B, D; Lafuse, W, P; Zwilling, B S. "Differential iron transport into phagosomes isolated from the RAW264.7 macrophage cell lines transfected with Nramp1Gly169 or Nramp1Asp169.." Journal of leukocyte biology. Vol. 66, no. 1. (January 1999.): 113-9.

Chen, L; Boomershine, C; Wang, T; Lafuse, W, P; Zwilling, B S. "Synergistic interaction of catecholamine hormones and Mycobacterium avium results in the induction of interleukin-10 mRNA expression by murine peritoneal macrophages.." Journal of neuroimmunology. Vol. 93, no. 1-2. (January 1999.): 149-55.

Wang, T; Lafuse, W, P; Zwilling, B S. "Regulation of toll-like receptor 2 expression by macrophages following Mycobacterium avium infection.." J Immunol. Vol. 165, no. 11. (January 2000.): 6308-13.

Lafuse, W, P; Alvarez, G, R; Zwilling, B S. "Regulation of Nramp1 mRNA stability by oxidants and protein kinase C in RAW264.7 macrophages expressing Nramp1(Gly169).." The Biochemical journal. Vol. 351 Pt 3, (January 2000.): 687-96.

Zhong, W; Lafuse, W, P; Zwilling, B S. "Infection with Mycobacterium avium differentially regulates the expression of iron transport protein mRNA in murine peritoneal macrophages.." Infection and immunity. Vol. 69, no. 11. (January 2001.): 6618-24.

Wang, T; Lafuse, W, P; Zwilling, B S. "NFkappaB and Sp1 elements are necessary for maximal transcription of toll-like receptor 2 induced by Mycobacterium avium.." J Immunol. Vol. 167, no. 12. (January 2001.): 6924-32.

Kuhn, D, E; Lafuse, W, P; Zwilling, B S. "Iron transport into mycobacterium avium-containing phagosomes from an Nramp1(Gly169)-transfected RAW264.7 macrophage cell line.." Journal of leukocyte biology. Vol. 69, no. 1. (January 2001.): 43-9.

Wang, Tianyi; Lafuse, William, P; Takeda, Kiyoshi; Akira, Shizuo; Zwilling, Bruce S. "Rapid chromatin remodeling of Toll-like receptor 2 promoter during infection of macrophages with Mycobacterium avium.." J Immunol. Vol. 169, no. 2. (January 2002.): 795-801.

Lafuse, William, P; Alvarez, Gail, R; Zwilling, Bruce S. "Role of MAP kinase activation in Nramp1 mRNA stability in RAW264.7 macrophages expressing Nramp1(Gly169).." Cellular immunology. Vol. 215, no. 2. (January 2002.): 195-206.

Alvarez, Gail, R; Zwilling, Bruce, S; Lafuse, William P. "Mycobacterium avium inhibition of IFN-gamma signaling in mouse macrophages: Toll-like receptor 2 stimulation increases expression of dominant-negative STAT1 beta by mRNA stabilization.." J Immunol. Vol. 171, no. 12. (January 2003.): 6766-73.

Weatherby, Kelly, E; Zwilling, Bruce, S; Lafuse, William P. "Resistance of macrophages to Mycobacterium avium is induced by alpha2-adrenergic stimulation.." Infection and immunity. Vol. 71, no. 1. (January 2003.): 22-9.

Curry, Heather; Alvarez, Gail, R; Zwilling, Bruces, S; Lafuse, William P. "Toll-like receptor 2 stimulation decreases IFN-gamma receptor expression in mouse RAW264.7 macrophages.." Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. Vol. 24, no. 12. (January 2004.): 699-710.

Wang, Yue; Curry, Heather, M; Zwilling, Bruce, S; Lafuse, William P. "Mycobacteria inhibition of IFN-gamma induced HLA-DR gene expression by up-regulating histone deacetylation at the promoter region in human THP-1 monocytic cells.." J Immunol. Vol. 174, no. 9. (January 2005.): 5687-94.

Bhardwaj, Neeti; Rosas, Lucia, E; Lafuse, William, P; Satoskar, Abhay R. "Leishmania inhibits STAT1-mediated IFN-gamma signaling in macrophages: increased tyrosine phosphorylation of dominant negative STAT1beta by Leishmania mexicana.." International journal for parasitology. Vol. 35, no. 1. (January 2005.): 75-82.

Studebaker, A, W; Lafuse, W, P; Kloesel, R; Williams, M V. "Modulation of human dUTPase using small interfering RNA.." Biochemical and biophysical research communications. Vol. 327, no. 1. (January 2005.): 306-10.

Lafuse, William, P; Alvarez, Gail, R; Curry, Heather, M; Zwilling, Bruce S. "Mycobacterium tuberculosis and Mycobacterium avium inhibit IFN- gamma -induced gene expression by TLR2-dependent and independent pathways.." Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. Vol. 26, no. 8. (January 2006.): 548-61.

Sow, Fatoumata, B; Florence, William, C; Satoskar, Abhay, R; Schlesinger, Larry, S; Zwilling, Bruce, S; Lafuse, William P. "Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis.." Journal of leukocyte biology. Vol. 82, no. 4. (January 2007.): -.

Barbi J; Cummings HE; Lu B; Oghumu S; Rückle T; Rommel C; Lafuse W; Whitacre CC; Satoskar AR. "PI3Kgamma (PI3Kgamma) is essential for efficient induction of CXCR3 on activated T cells.." Blood. Vol. 112, no. 8. (October 2008.): 3048-.

Van Zandt KE; Sow FB; Florence WC; Zwilling BS; Satoskar AR; Schlesinger LS; Lafuse WP. "The iron export protein ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome.." Journal Of Leukocyte Biology. Vol. 84, no. 3. (September 2008.): 689-.

Sow FB; Alvarez GR; Gross RP; Satoskar AR; Schlessinger LS; Zwilling BS; Lafuse WP. "Role of STAT1, NF-kappaB, and C/EBPbeta in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-gamma." Journal of Leukocyte Biology. Vol. 86, no. 5. (January 2009.): 1247-1258.

Roth KM; Gunn JS; Lafuse W; Satoskar AR. "Francisella inhibits STAT1-mediated signaling in macrophages and prevents activation of antigen-specific T cells.." International Immunology. Vol. 21, no. 1. (January 2009.): 19-.

Allen, R.G., Lafuse, W.P, Galley, J.D., Ali, M.M., Ahmer, B.M, and Bailey, M.T.. "The intestinal microbiota are necessary for stressor-induced enhancement of splenic macrophage microbicidal activityy." Brain, Behavior, and Immunity. (November 2011.): -.

Sow, F.B, Nandakumar,S.,Velu, V., Kellar, K.L., Schlesinger, L.S., Amara, R.R., Lafuse, W.P., Shinnick, T.M, and Sable, S.B. "Mycobacterial tuberculosis components stimulate production of the antimicrobial peptide hepcidin." Tuberculosis. Vol. 91, (January 2011.): 314-321.

 

Reference Works

January 1979 Lafuse, W.P., Neely, B., McKean, D., and David, C.S.."Biochemical studies of Ia gene products with xenoantisera" . : 6303
January 1981 Long, P.M., Lafuse, W.P., Krco, C.J., and David, C.S.."Serological, biochemical, and cellular studies of minor histocompatibility antigens" . : 1159
January 1981 Lafuse, W.P., Freed, J.H., and David, C.S.."Serological and biochemical studies of mutant Ae(E?) Ia polypeptide chain in D.2GD(H-2g2)" . : 1010
January 1982 Singh, S.K., Lafuse, W.P., McKean, D.J., and David, C.S.."Evidence for multiple I-E molecules in H-2d tumor cell lines" . : 612
January 1982 Long, P.M., Lafuse, W.P., Krco, C.J., and David, C.S.."Serological, biochemical, and cellular studies of minor histocompatibility antigens" . : 427
January 1982 Lafuse, W.P., Corser, P., Pierres, M., and David, C.S.."Crossreactions of monoclonal anti-I-E antibodies with subsets of I-Ab molecules" . : 365
January 1984 Levy, N., Singh, S., Lafuse, W.P., and David, C.S.."Analysis of I-E? polypeptide chains in murine I-A recombinant strains" . : 1599
January 1984 Lafuse, W.P., Singh, S., Pierres, M., and David, C.S.."Isolation and structural characterization of subsets of I-Ab molecules" . : 1959
January 1985 Levy, N.E, Lafuse, W.P., Savarirayan, S., Duran, L., Pease, L., and David, C.S.."Gene order of the H-2D region" . : 553
January 1985 Lafuse, W.P., Hirose, S., McCormick, J.F., and David, C.S.."Serological evidence for gene conversion in mouse Ia genes" . : 557
January 1985 Lafuse, W. P., Hirose, S., McCormick, J.F., and C.S. David."Serologic evidence for gene conversion like events in mouse Ia genes" .
January 1985 David, C.S., Savarirayan, S., McCormick, J.F., Lafuse, W.P. Levy, N., Duran, L. and Pease, L.."Genetics of the H-2D Region" .
January 1986 Lafuse, W.P., Berg, N., Savarirayan, S., and David, C.S.."Mapping of a second recombination 'hot spot' within the I region of the mouse H-2 complex" . : 988
January 1987 Lafuse, W.P. and David, C.S.."Recombination sites within the Mouse H-2 Complex" Bar Harbor, Maine.
January 1987 Savarirayan, S. Hanson, J., McCormick, J., Lafuse, W.P., and David, C.S.."Identification and characterization of new intra-H-2 recombinants" . : 944
January 1988 Lafuse, W.P. Castle, L.M., and David, C.S.."Restriction Fragment Length Polymorphism Analysis of C-2 and Factor B genes in mouse H-2 recombinant mouse strains" .
January 1990 Lafuse, W. P., Castle, L., and David, C.S.."RFLP analysis of HSP70 genes in the mouse H-2 Complex" .
January 1991 Lanning, D., Castle, L., Lafuse, W.P., and David, C.S.."RFLP analysis of genes mapping in the S-D Region of the Mouse H-2 complex" .
January 1991 Lafuse, W., Jung, J., Kaiser, M., and Zwilling, B.."Characterization of macrophage IFN-gamma induced genes" .
January 1992 Lafuse, W.P., Brown, D., Castle, L., and Zwilling, B.S.."Characterization of Novel Genes Induced in Macrophages by IFN-gamma" . : 53
January 1992 Lafuse, W.P., Brown,D., Castle, L., and Zwilling, B.S.."Characterization of cDNA's Induced in Macrophages by IFN-gamma" .
January 1994 Lafuse, W.P., Brown, D., Hussain, S., and Zwilling, B.."Characterization of a novel gene that is IFN-? induced in mouse macrophages and encodes a GTP binding proten" .
January 1994 Jung, J., Lafuse, W.P., Marucha, P.T., and Sheridan,J.F.."Patterns of cytokine gene expression in the draining lymph node and lung of Influenza virus infected mice" .
January 1994 Hussain, S. and Lafuse, W.P.."Differential expression of IFn-? inducible genes in various murine macrophage cell lines" .
January 1995 Jung, J., Lafuse, W.P., Marucha, P.T., and Sheridan, J.F.."Differential Expression of Cytokine Genes in different microenvironments during an influenza viral infection: Effect of restraint stress" . : 156
January 1995 Hussain, S. and Lafuse, W.P.."Mg21 is an IFN-? induced gene in mouse macrophages and encodes an intracellular protein with GTP-binding activity" . : 528
January 1995 Zwilling, B,S., Lafuse, W., and Brown, D.."Corticosterone regulation of mycobacterial resistance in BCG resistant and susceptible mice" .
January 1995 Brown, D.H., Lafuse, W.P., and Zwilling, B.S.."Regulation of Nramp expression by GM-CSF activated macrophages: Differential effects of glucocorticoids" .
January 1996 Hussain,S., Lafuse, W.P., Brown,D., Castle, L., and Zwilling, B.S.."Cloning and characterization of a novel gene induced by IFN-? in mouse macrophages" .
January 1998 Hussain, S., Zwilling, B.S., and Lafuse, W.P. `."Mycobacterium avium infected mouse macrophages show unresponsiveness to IFN-? and defective JAK-STAT cell signaling pathway" . : 1733
January 1998 Kuhn, D.E.. Lafuse, W.P., and Zwilling, B.S.."Iron transport by isolated phagolysosomes (PL) obtained from the RAW264.7 macrophage (M?) cell line transfected with resistant" . : 1611
January 2000 Wang, T., Lafuse, W.P., and Zwilling, B.S.."Regulation of Toll-like receptor 2 expression" .
January 2000 Lafuse, W. P., Alvarez, G.R., and Zwilling, B.S.."Regulation of NRAMP1 mRNA stability by oxidants and protein kinase C" .
January 2000 Kuhn, D.E., Lafuse, W.P., and Zwilling, B.S.."Regulation of NRAMP1 mediated iron transport" .
January 2001 Zhong, W., Lafuse, W.P., and Zwilling, B.S.."Infection with Mycobacterium avium differentially regulates the expression of iron transport protein mRNA in murine" .
January 2001 Weatherby, K.M., Lafuse, W.P., and Zwilling, B.S.."Increased resistance to mycobacterial growth by alpha-2 adrenergic stimulation of macrophages requires both nitric oxide and superoxide production" .
January 2001 Wang, T., Lafuse, W.P., and Zwilling, B.S.."NF??-mediated TLR2 gene expression" .
January 2001 Bishop, C.M., Kuhn, D.E., Lafuse, W.P. and Zwilling, B.S.."The consensus transport signature sequence of Nramp1 is required for iron transport" .
January 2001 Lafuse, W.P., Alaverz, G.R., and Zwilling, B.S.."Mycobacterium avium infection of macrophages induces protein binding to the 3’UTR of Nramp1 mRNA" .
January 2005 Van Zandt, K.E., Zwilling, B.S., and Lafuse, W.P.."The induction of Nramp1 (SLC11a1) by Francisella tularensis is dependent of TLR2" .
January 2005 Lafuse, W.P. Alvarez, G.R., Curry, H.M., and Zwilling, B.S.."Inhibition of IFN-? induced gene expression by M. avium involves both TLR2 dependent and independent pathways" .

Presentations

"Recombinant hot spots in the mouse H-2 Complex." Presented at OSU Immunology Seminar, . (October 1986)

"Recombination sites in the mouse H-2 major histocompatibility complex." Presented at OSU Immuniology Seminar, . (May 1988)

"Recombination sites and chromosome walking in the mouse H-2 major histocompatibility complex." Presented at OSU Immunology Seminar, . (April 1989)

"The search for genes linked to the BCG resistance gene in the mouse." Presented at OSU Immuniology Seminar, . (April 1990)

"Molecular biology of macrophage IFN-g induced genes." Presented at OSU Immunology Seminar, . (October 1991)

"Molecular biology of genes induced in macrophages." Presented at OSU Immunology Seminar, . (May 1993)

"Molecular biology of mouse macrophage activation by inerferon-gamma." Presented at OSU Immunology Seminar, . (May 1994)

"IFN-g signaling in mouse macrophages: autoregulation of Stat I expression and activation." Presented at OSU Immunology Seminar, . (October 1995)

"Molecular studies of gene induction and expression in activated mouse macrophages." Presented at OSU Immunology Seminar, . (April 1995)

"mRNA stability and RNA binding activity in IFN-gamma activated mouse macrophages." Presented at OSU Immunology Seminar, . (April 1997)

"mRNA stability and RNA binding activity in IFN-gamma activated mouse macrophages." Presented at Department of Medical Microbiology and Immunology Seminar, . (April 1997)

"Inhibition of interferon-gamma induced gene expression and signaling in mouse macrophages by infection with Mycobacterium avium." Presented at OSU Immunology Seminar, . (March 1998)

"The role of oxidants and protein kinase C in mRNA stability of mouse Nramp 1 (Natural Resistance Associated Macrophage Protein 1)." Presented at OSU Immunology Seminar, . (June 1999)

"Regulation of Nramp 1 Mediated Iron Transport." Presented at National Institutes of Health, . (April 2001)

"The role of oxidant generated signaling pathways in Nramp 1 mRNA stability and RNA binding proteins." Presented at OSU Immunology Seminar, . (March 2001)

"Role of Oxidant signaling pathways in Natural Resistance Associated Macrophage Protein 1 (Nramp 1) mRNA stability." Presented at OSU MCIMG Seminar, . (January 2002)

"Modulation of macrophage functions by catecholamines." Presented at OSU Immunology Seminar, . (February 2004)

"Macrophage resistance to Mycobacterium avium is induced by ?2-Adrenergic stimulation." Presented at PNIRS 2003 Meeting, . (June 2004)

"Inhibition of IFN-gamma induced gene expression in macrophages by mycobacteria infection." Presented at Department of Microbiology, Medical College of Ohio, . (March 2005)

"Expression and function of hepcidin and the iron export Protein ferroportin 1 in Mycobacteria Infected Macrophages." Presented at OSU Immunology Seminar, . (October 2006)

"Hepcidin and Mycobacteria: Expression, Anti-Bacterial Activity and Phagosome Localization of Hepcidin in Infected Macrophages." Presented at MVIMG Dept. Seminar, Columbus, OH. (March 2007)

"Hepcidin and Mycobacteria: Expression, Anti-Bacterial Activity and Phagosome Localization of Hepcidin in Infected Macrophages." Presented at OSU Immunology Seminar, Columbus, OH. (October 2008)

"The Anti-Microbial peptide Hepcidin, Macrophage, and Mycobacterium tuberculosis." Presented at MVIMG Department Seminar, Columbus, OH. (June 2008)

"Hepcidin and Anemai during psychologcial stress and infection." Presented at MVIMG Dept. Seminar, . (November 2009)