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Vijay Pancholi, PhD


Staff photo

420 W 12th Ave
Columbus, OH 43210

Phone: (614) 688-8053

Email: pancholi.2@osu.edu

 

Current OSU Appointments

Research Associate Professor, Pathology

Research Associate Professor, SBS-Microbial Infectn/Immunity

 

Academic Advising

2006 - 2010 Amanda Beltramini, The Ohio State University. Graduated 2010. Eukaryotic-like serine/threonine kinase signaling in Staphylococcus aureus
 

Chapters in Books

Fischetti VA, Pancholi V, Schneewind O. "Common Characteristics of Surface Proteins from Gram-Positive Cocci." In Genetics and Molecular Biology of Streptococci, Lactococci, and Enterococci. Edited by GM Dunny, PP Cleary, LL McKay. 290-294. Washington, D.C.: ASM Publication, January 1991.

Fischetti VA, Pancholi V, Sellers P, Schmidt J, Landau G, Xu X, Schneewind O. "Streptococcal M Protein: A Common Structural Motif Used by Gram-Positive Bacteria for Biologically Active Surface Molecules." In FEMS Molecular Recognition in Host-Parasite Interactions. Edited by TK Korhonen, T Hovi, PH Makela. 31-38. New York, NY: Plenum Publishing Corp., January 1991.

Schneewind O, Pancholi V, Fischetti VA. "Surface Proteins from Gram-Positive Cocci Have a Common Motif for Membrane Anchoring." In Genetics and Molecular Biology of Streptococci, Lactococci, and Enterococci. Edited by GM Dunny, PP Cleary, LL McKay. 152-154. Washington, D.C.: ASM Publication, January 1991.

Fischetti VA, Pancholi V, Schneewind O. "Surface Proteins from Gram-Positive Cocci Share Unique Structural Features." In New Perspectives on Streptococci and Streptococcal Infections. Edited by G Orefici. 165-167. New York, NY: Gustav Fischer, January 1992.

Pancholi V, Fischetti VA. "Glyceraldehyde-3-Phosphate Dehydrogenase on the Surface of Group A Streptococci is Also an ADP-Ribosylating Enzyme." In Streptococci: Present and Future. Edited by A Totolian. 131-133. St. Petersburg: Lancer Publications, January 1993.

Pancholi V, Fischetti VA. "Cell-to-cell Signaling Between Group A Streptococci and Pharyngeal Cells: Role of Streptococcal Surface Dehydrogenase (SDH)." In Streptococci and the Host. Vol. 418. Edited by T Horaud, N Bouvet, R Leclercq, H de Montclos, M Sicard. 499-504. New York, NY: Plenum Press, January 1997.

Pancholi V, Fischetti VA. "A Novel Plasminogen/Plasmin Binding Protein on the Surface of Group A Streptococci." In Streptococci and the Host. Vol. 418. Edited by T Horaud, N Bouvet, R Leclercq, H de Montclos, M Sicard. 597-599. New York, NY: Plenum Press, January 1997.

Fischetti VA, Vashista A, Pancholi V. "Streptococcal M Protein: Structure, Function and Immunology." In Rheumatic Fever. Edited by J Narula, R Virmani, KS Reddy, R Tandon. 113-133. Washington, D.C.: American Registry of Pathology; Armed Forces Institute of Pathology, January 1999.

Pancholi V. "Streptococci-Mediated Host Cell Signaling." In Gram-Positive Pathogens. Edited by VA Fischetti, R Novick, J Ferretti, D Portnoy, J Rood. 87-95. Washington, D.C.: ASM Publications, January 1999.

Pancholi V. "Staphylococcal Extracellular/Surface Enzymatic Activity." In Staphylococcal Infection and Immunity. Edited by A Honeyman, H Friedman, M Bendinelli. 137-154. New York, NY: Kluwer/Plenum, January 2001.

Pancholi V. "Streptococcus-mediated Host Cell Signaling." In Gram-Positive Pathogens. 2nd ed. Edited by VA Fischetti, R Novick, J Ferretti, D Portnoy, J Rood. 100-112. Washington, D.C.: ASM Press, January 2006.

 

Degrees

1974 B.S., Gujarat University

1977 M.S., Gujarat University

1984 Ph.D., Postgraduate Institute of Medical Education & Research

 

Editorial Activities

present Folia Microbiologica
present EMBO Journal
present Cellular Microbiology
present Biochemical Journal
present
present Trends in Microbiology
present Molecular Microbiology
present Journal of Proteomic Res
present Journal of Bacteriology
present Journal Medical Microbiology
present J. Proteome Research
present Infection and Immunity
present Current topic in Microbiology
present PloS pathogens
present PloS One
present Microbiology
present Microbial Pathogenesis
1988 - present Journal of Infectious Disease
2007 - present Brock's Microbiology
2008 - present Journal of Immunology
2010 - present BMC Microbiology
 

Honors

2006 - 2008 OSUMC Strategic Initiatve Grant. Ohio State University Medical Center.
2009 - 2012 Grand Challenege III. Bill and Melinda Gates Foundation.
 

Journal Articles

Ayyagari A, Pancholi V, Pandhi SC, Goswami A, Agarwal KC, Mehra YN. "Anaerobic-bacteria in chronic suppurative otitis-media." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 73, no. JUN. (January 1981.): 860-864.

Ayyagari A, Pancholi V, Goswami A, Malik SK, Agarwal KC. "Anaerobic-bacteria in pleuropulmonary infections." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 74, no. DEC. (January 1981.): 809-814.

Pancholi V, Ayyagari A, Agarwal KC. "Initial screening- test of primary clinical specimens in UV light for bacteroides-melaninogenicus and bacteroides-asaccharolyticus." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 76, no. SEP. (January 1982.): 386-392.

Pancholi V, Ayyagari A, Agarwal KC. "Initial screening test of primary clinical specimens in UV light for Bacteroides melaninogenicus and B. asaccharolyticus.." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 76, (September 1982.): 386-392.

Pancholi V, Ayyagari A, Agarwal KC. "Initial screening test of primary clinical specimens in UV light for Bacteroides melaninogenicus and B. asaccharolyticus." Indian J Med Res. Vol. 76, (September 1982.): 386-392.

Ayyagari A, Ganju S, Pancholi V, Sahni HS, Agarwal KC, Walia BS. "A preliminary-report on campylobacter enteritis." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 76, no. DEC. (January 1982.): 829-831.

Ayyagari A, Ganju S, Pancholi V, Sahni HS, Agarwal KC, Walia BN. "A preliminary report on Campylobacter enteritis." Indian J Med Res. Vol. 76, (December 1982.): 829-831.

Pancholi V, Ayyagari A, Agarwal KC. "Role of hemagglutinating bacteroides-asaccharolyticus in clinical infections." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 77, no. MAR. (January 1983.): 324-328.

Pancholi V, Ayyagari A, Agarwal KC. "Role of haemagglutinating Bacteroides asaccharolyticus in clinical infections." Indian J Med Res. Vol. 77, (March 1983.): 324-328.

Ayyagari A, Pancholi V, Kak VK, Kumar N, Khosla VK, Agarwal KC, Gulati DR. "Bacteriological spectrum of brain-abscess with special reference to anaerobic-bacteria." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 77, no. FEB. (January 1983.): 182-186.

Ayyagari A, Pancholi VK, Kak VK, Kumar N, Khosla VK, Agarwal KC, Gulati DR. "Bacteriological spectrum of brain abscess with special reference to anaerobic bacteria." Indian J Med Res. Vol. 77, (February 1983.): 182-186.

Ayyagari A, Ganju S, Pancholi V, Das U, Agarwal KC. "Minimum inhibitory concentration of various antibiotics against clostridium-tetani." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 80, no. DEC. (January 1984.): 638-641.

Ayyagari A, Kumar L, Agarwal KC, Ganju S, Sharma P, Pancholi V. "Prevalence of serotypes of Streptococcus-pneumoniae in patients in and around chandigarh." INDIAN JOURNAL OF MEDICAL RESEARCH. Vol. 79, no. FEB. (January 1984.): 174-177.

Ayyagari A, Kumar L, Agarwal KC, Ganju S, Sharma P, Pancholi V. "Prevalence of serotypes of Streptococcus pneumoniae in patients in and around Chandigarh." Indian J Med Res. Vol. 79, (February 1984.): 174-177.

Ayyagari A, Ganju S, Sharma P, Pancholi VK, Panigrahi D, Agarwal KC, Walia BN. "Detection of Campylobacter coli in diarrhoeal and non-diarrhoeal children in India.." Journal of Diarrhoeal Diseases Research. Vol. 2, no. 4. (December 1984.): 228-231.

Ayyagari A, Ganju S, Sharma P, Pancholi VK, Panigrahi D, Agarwal KC, Walia BN. "Detection of Campylobacter coli in diarrhoeal and non-diarrhoeal children in India." J Diarrhoeal Dis Res. Vol. 2, no. 4. (December 1984.): 228-231.

Ayyagari A, Ganju S, Pancholi V, Das U, Agarwal KC. "Minimum inhibitory concentration of various antibiotics against Clostridium tetani." Indian J Med Res. Vol. 80, (December 1984.): 638-641.

Pancholi V, Ayyagari A, Agarwal KC. "Cell-mediated immune-response in rats immunized with bacteroides-melaninogenicus." IRCS MEDICAL SCIENCE-BIOCHEMISTRY. Vol. 12, no. 9. (January 1984.): 843-844.

Larroya S, Johl PP, Pancholi V, Khuller GK. "Preparation and isolation of spheroblasts from dermatophytes." IRCS MEDICAL SCIENCE-BIOCHEMISTRY. Vol. 12, no. 11. (January 1984.): 1064-1065.

Gupta R, Pancholi V, Vinayak VK, Khuller GK. "Protective immunity to systemic nocardiosis in mice immunized with cell extract antigens of nocardia-asteroides." MEDICAL MICROBIOLOGY AND IMMUNOLOGY. Vol. 174, no. 3. (January 1985.): 157-166.

Gupta R, Pancholi V, Vinayak VK, Khuller GK. "Immunological responses to protein, carbohydrate and lipid fractions of nocardia-asteroides in mice." JOURNAL OF MEDICAL MICROBIOLOGY. Vol. 20, no. 2. (January 1985.): 263-274.

Pancholi V, Ayyagari AS, Agarwal KC. "Experimentally induced subcutaneous infection by black pigmented bacteroides species in rats." JOURNAL OF INFECTION. Vol. 11, no. 2. (January 1985.): 131-137.

Pancholi V, Ayyagari A, Agarwal KC. "Indirect serum hemaglutinating antibody-response to black pigmented bacteroides during experimental pure infections in rats." MEDICAL MICROBIOLOGY AND IMMUNOLOGY. Vol. 173, no. 6. (January 1985.): 319-328.

Pancholi V, Ayyagari A, Agarwal KC. "Effect of the presence of black pigmented bacteroides of differing pathogenicity on the phagocytosis of escherichia-coli by rat polymorphonuclear leukocytes." MEDICAL MICROBIOLOGY AND IMMUNOLOGY. Vol. 174, no. 3. (January 1985.): 131-137.

Pancholi V, Ayyagari A, Agarwal KC. "Indirect serum haemagglutinating antibody response to black pigmented Bacteroides during experimental pure infections in rats." Med Microbiol Immunol. Vol. 173, no. 6. (January 1985.): 319-328.

Pancholi V, Ayyagari A, Agarwal KC. "Effect of the presence of black pigmented Bacteroides of differing pathogenicity on the phagocytosis of Escherichia coli by rat polymorphonuclear leucocytes." Med Microbiol Immunol. Vol. 174, no. 3. (January 1985.): 131-137.

Gupta R, Pancholi V, Vinayak VK, Khuller GK. "Protective immunity to systemic nocardiosis in mice immunized with cell extract antigens of Nocardia asteroides." Med Microbiol Immunol. Vol. 174, no. 3. (January 1985.): 157-166.

Pancholi V, Ayyagari AS, Agarwal KC. "Experimentally induced subcutaneous infection by black pigmented Bacteroides species in rats." J Infect. Vol. 11, no. 2. (September 1985.): 131-137.

Gupta R, Pancholi V, Vinayak VK, Khuller GK. "Immunological responses to protein, carbohydrate and lipid fractions of Nocardia asteroides in mice." J Med Microbiol. Vol. 20, no. 2. (October 1985.): 263-274.

Gupta R, Pancholi V, Vinayak VK, Khuller GK. "Immune responses to the protein, carbohydrate and lipid antigens of Nocardia asteroides in experimental nocardiosis in mice." J Med Microbiol. Vol. 20, no. 2. (October 1985.): 255-261.

Pancholi V, Ayyagari A, Agarwal KC. "Phagocytosis of 2 species of black pigmented bacteroides of differing pathogenicity by rat polymorphonuclear leukocytes." IRCS MEDICAL SCIENCE-BIOCHEMISTRY. Vol. 13, no. 2. (January 1985.): 143-144.

Gupta R, Pancholi V, Vinayak VK, Khuller GK. "Immune-responses to the protein, carbohydrate and lipid antigens of nocardia-asteroids in experimental nocardiosis in mice." JOURNAL OF MEDICAL MICROBIOLOGY. Vol. 20, no. 2. (January 1985.): 255-261.

Ayyagarí A, Pancholi VK, Kak VK, Kumar N, Khosla VK, Agarwal KC, Gulati DR. "Role of anaerobes and chemotherapy in brain abscess." INDIANN JOURNAL OF PATHOLOGY AND MICROBIOLOGY. Vol. 28, no. 1. (January 1985.): 1-6.

Ayyagari A, Pancholi VK, Kak VK, Kumar N, Khosla VK, Agarwal KC, Gulati DR. "Role of anaerobes and chemotherapy in brain abscess." Indian J Pathol Microbiol. Vol. 28, no. 1. (January 1985.): 1-6.

Cheema S, Asotra S, Pancholi V, Khuller GK. "Effect of ethanol on phospholipid-composition, drug susceptibility and amino-acid uptake in ethambutol-sensitive and ethambutol-resistant mycobacterium-segmatis ATCC-607." IRCS MEDICAL SCIENCE-BIOCHEMISTRY. Vol. 14, no. 3. (March 1986.): 229-230.

Pancholi V, Fischetti VA. "Isolation and characterization of the cell-associated region of Group-A streptococcal M6 protein." JOURNAL OF BACTERIOLOGY. Vol. 170, no. 6. (June 1988.): 2618-2624.

Pancholi V, Fischetti VA. "Isolation and characterization of the cell-associated region of group A streptococcal M6 protein." J Bacteriol. Vol. 170, no. 6. (June 1988.): 2618-2624.

Pancholi V, Fischetti VA. "Identification of an endogenous membrane anchor-cleaving enzyme for group A streptococcal M protein. Its implication for the attachment of surface proteins in gram-positive bacteria.." J Exp Med. Vol. 170, no. 6. (December 1989.): 2119-2133.

Pancholi V, Fischetti VA. "Identification of an endogenous membrane anchor-cleaving enzyme for Group-A streptococcal M-protein - Its implications for the attachment of surface-proteins in gram-positive bacteria." JOURNAL OF EXPERIMENTAL MEDICINE. Vol. 170, no. 6. (December 1989.): 2119-2133.

Fischetti VA, Pancholi V, Schneewind O. "Conservation of a hexapeptide sequence in the anchor region of surface-proteins from gram-positive cocci." MOLECULAR MICROBIOLOGY. Vol. 4, no. 9. (September 1990.): 1603-1605.

Fischetti VA, Pancholi V Schneewind O. "Conservation of a hexapeptide sequence in the anchor region of surface proteins from gram-positive cocci.." Mol Microbiol. Vol. 4, no. 9. (September 1990.): 1603-1605.

Pancholi V, Fischetti VA. "A major surface protein on group A streptococci is a glyceraldehyde-3-phosphate-dehydrogenase with multiple binding activity.." J Exp Med. Vol. 176, no. 2. (August 1992.): 415-426.

Pancholi V, Fischetti VA. "A major surface protein on Group-A Streptococci is a glyceraldehyde-3-phosphate-dehydrogenase with multiple binding-activity." JOURNAL OF EXPERIMENTAL MEDICINE. Vol. 176, no. 2. (August 1992.): 415-426.

Pancholi V. Fischetti VA. "Glyceraldehyde-3-phosphate dehydrogenase on the surface of group A streptococci is also an ADP-ribosylating enzyme.." Proc Natl Acad Sci USA. Vol. 90, no. 17. (September 1993.): 8154-8158.

Pancholi V, Fischetti VA. "Glyceraldehyde-3-phosphate dehydrogenase on the surface of group-A Streptococci is also an ADP-ribosylating enzyme." PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Vol. 90, no. 17. (September 1993.): 8154-8158.

Ren K, Bannan JD, Pancholi V, Cheung AL, Robbins JC, Fischetti VA, Zabriskie JB. "Characterization and biological properties of a new staphylococcal exotoxin." J Exp Med. Vol. 180, no. 5. (November 1994.): 1675-1683.

Ren KY, Bannan JD, Pancholi V, Cheung AL, Robbins JC, Fischetti VA, Zabriskie JB. "Characterization and biological properties of a new staphylococcal exotoxin." JOURNAL OF EXPERIMENTAL MEDICINE. Vol. 180, no. 5. (November 1994.): 1675-1683.

Fischetti VA, Horstmann RD, Pancholi V. "Location of the complement factor-H binding-site on Streptococcal M6 protein." INFECTION AND IMMUNITY. Vol. 63, no. 1. (January 1995.): 149-153.

Fischetti VA, Horstmann RD, Pancholi V. "Location of the complement factor H binding site on streptococcal M6 protein." Infect Immun. Vol. 63, no. 1. (January 1995.): 149-153.

Pancholi V, Fischetti VA. "Cell-to-cell signalling between group A streptococci and pharyngeal cells. Role of streptococcal surface dehydrogenase (SDH)." Adv Exp Med Biol. Vol. 418, (January 1997.): 499-504.

Pancholi V, Fischetti VA. "Cell-to-cell signalling between group a streptococci and pharyngeal cells - Role of Streptococcal Surface Dehydrogenase (SDH)." STREPTOCOCCI AND THE HOST. Vol. 418, (January 1997.): 499-504.

Pancholi V, Fischetti VA. "A novel plasminogen/plasmin binding protein on the surface, of group A streptococci." STREPTOCOCCI AND THE HOST. Vol. 418, (January 1997.): 597-599.

Pancholi,V; Fischetti,V,A. "Regulation of the phosphorylation of human pharyngeal cell proteins by group a streptococcal surface dehydrogenase: Signal transduction between streptococci and pharyngeal cells." JOURNAL OF EXPERIMENTAL MEDICINE. Vol. 186, no. 10. (November 1997.): 1633-1643.

Pancholi V, Fischetti VA. "Regulation of the phosphorylation of human pharyngeal cell proteins by group A streptococcal surface dehydrogenase: signal transduction between streptococci and pharyngeal cells." J Exp Med. Vol. 186, no. 10. (November 1997.): 1633-1643.

Pancholi V, Fischetti VA. "A novel plasminogen/plasmin binding protein on the surface of group A streptococci." Adv Exp Med Biol. Vol. 418, (January 1997.): 597-599.

Pancholi V, Fischetti VA. "alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 273, no. 23. (June 1998.): 14503-14515.

Pancholi V, Fischetti VA. "alpha-enolase, a novel strong plasmin(ogen) binding protein on the surface of pathogenic streptococci." J Biol Chem. Vol. 273, no. 23. (June 1998.): 14503-14515.

Fontan PA, Pancholi V, Nociari MM, Fischetti VA. "Antibodies to streptococcal surface enolase react with human alpha-enolase: implications in poststreptococcal sequelae." J Infect Dis. Vol. 182, no. 6. (December 2000.): 1712-1721.

Fontan PA, Pancholi V, Nociari MM, Fischetti VA. "Antibodies to streptococcal surface enolase react with human alpha-enolase: Implications in poststreptococcal sequelae." JOURNAL OF INFECTIOUS DISEASES. Vol. 182, no. 6. (December 2000.): 1712-1721.

Broudy TB, Pancholi V, Fischetti VA. "Induction of lysogenic bacteriophage and phage-associated toxin from group A streptococci during coculture with human pharyngeal cells." INFECTION AND IMMUNITY. Vol. 69, no. 3. (March 2001.): 1440-1443.

Ryan PA, Pancholi V, Fischetti VA. "Group A streptococci bind to mucin and human pharyngeal cells through sialic acid-containing receptors." INFECTION AND IMMUNITY. Vol. 69, no. 12. (December 2001.): 7402-7412.

Pancholi V. "Multifunctional alpha-enolase: its role in diseases." Cell Mol Life Sci. Vol. 58, no. 7. (June 2001.): 902-920.

Ryan PA, Pancholi V, Fischetti VA. "Group A streptococci bind to mucin and human pharyngeal cells through sialic acid-containing receptors." Infect Immun. Vol. 69, no. 12. (December 2001.): 7402-7412.

Broudy TB, Pancholi V, Fischetti VA. "Induction of lysogenic bacteriophage and phage-associated toxin from group a streptococci during coculture with human pharyngeal cells." Infect Immun. Vol. 69, no. 3. (March 2001.): 1440-1443.

Pancholi V. "Multifunctional alpha-enolase: Its role in diseases." CELLULAR AND MOLECULAR LIFE SCIENCES. Vol. 58, no. 7. (June 2001.): 902-920.

Lee SG, Pancholi V, Fischetti VA. "Characterization of a unique glycosylated anchor endopeptidase that cleaves the LPXTG sequence motif of cell surface proteins of gram-positive bacteria." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 277, no. 49. (December 2002.): 46912-46922.

Lee SG, Pancholi VK, Fischetti VA. "Characterization of a unique glycosylated anchor endopeptidase that cleaves the LPXTG sequence motif of cell surface proteins of Gram-positive bacteria.." J Biol Chem. Vol. 277, no. 49. (December 2002.): 46912-46922.

Broudy TB, Pancholi V, Fischetti VA. "The in vitro interaction of Streptococcus pyogenes with human pharyngeal cells induces a phage-encoded extracellular DNase.." Infect Immun. Vol. 70, no. 6. (June 2002.): 2805-2811.

Broudy TB, Pancholi V, Fischetti VA. "The in vitro interaction of Streptococcus pyogenes with human pharyngeal cells induces a phage-encoded extracellular DNase." INFECTION AND IMMUNITY. Vol. 70, no. 6. (June 2002.): 2805-2811.

Pancholi V, Chhatwal GS. "Housekeeping enzymes as virulence factors for pathogens." INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY. Vol. 293, no. 6. (December 2003.): 391-401.

Sha J, Galindo CL, Pancholi V, Popov VL, Zhao Y, Houston CW, Chopra AK. "Differential expression of the enolase gene under in vivo versus in vitro growth conditions of Aeromonas hydrophila.." Microb Pathog. Vol. 34, no. 4. (April 2003.): 195-204.

Pancholi V, Fontan P, Jin H. "Plasminogen-mediated group A streptococcal adherence to and pericellular invasion of human pharyngeal cells.." Microb Pathog. Vol. 35, no. 6. (December 2003.): 293-303.

Pancholi V, Chhatwal GS. "Housekeeping enzymes as virulence factors for pathogens.." Int J Med Microbiol. Vol. 293, no. 6. (December 2003.): 391-401.

Pancholi V, Fontan P, Jin H. "Plasminogen-mediated group A streptococcal adherence to and pericellular invasion of human pharyngeal cells." MICROBIAL PATHOGENESIS. Vol. 35, no. 6. (December 2003.): 293-303.

Sha J, Galindo CL, Pancholi V, Popov VL, Zhao Y, Houston CW, Chopra AK. "Differential expression of the enolase gene under in vivo versus in vitro growth conditions of Aeromonas hydrophila." MICROBIAL PATHOGENESIS. Vol. 34, no. 4. (April 2003.): 195-204.

Derbise A, Song YP, Parikh S, Fischetti VA, Pancholi V. "Role of the C-terminal lysine residues of streptococcal surface enolase in Glu- and Lys-plasminogen-binding activities of group A streptococci." INFECTION AND IMMUNITY. Vol. 72, no. 1. (January 2004.): 94-105.

Derbise A, Song YP, Parikh S, Fischetti VA, Pancholi V. "Role of the C-terminal lysine residues of streptococcal surface enolase in Glu- and Lys-plasminogen-binding activities of group A streptococci.." Infect Immun. Vol. 72, no. 1. (January 2004.): 94-105.

Jin H, Song YP, Boel G, Kochar J, Pancholi V. "Group A streptococcal surface GAPDH, SDH, recognizes uPAR/CD87 as its receptor on the human pharyngeal cell and mediates bacterial adherence to host cells." JOURNAL OF MOLECULAR BIOLOGY. Vol. 350, no. 1. (July 2005.): 27-41.

Boel G, Jin H, Pancholi V. "Inhibition of cell surface export of group A streptococcal anchorless surface dehydrogenase affects bacterial adherence and antiphagocytic properties." INFECTION AND IMMUNITY. Vol. 73, no. 10. (October 2005.): 6237-6248.

Boel G, Jin H, Pancholi V. "Inhibition of cell surface export of group A streptococcal anchorless surface dehydrogenase affects bacterial adherence and antiphagocytic properties.." Infect Immun. Vol. 73, no. 10. (October 2005.): 6237-6248.

Jin H, Song YP, Boel G, Kochar J, Pancholi V. "Group A streptococcal surface GAPDH, SDH, recognizes uPAR/CD87 as its receptor on the human pharyngeal cell and mediates bacterial adherence to host cells.." J Mol Biol. Vol. 350, no. 1. (July 2005.): 27-41.

Jin H, Pancholi V. "Identification and biochemical characterization of a eukaryotic-type serine/threonine kinase and its cognate phosphatase in Streptococcus pyogenes: Their biological functions and substrate identification." JOURNAL OF MOLECULAR BIOLOGY. Vol. 357, no. 5. (April 2006.): 1351-1372.

Sundblad V, Bussmann L, Chiauzzi VA, Pancholi V, Charreau EH. "alpha-enolase: a novel autoantigen in patients with premature ovarian failure." CLINICAL ENDOCRINOLOGY. Vol. 65, no. 6. (December 2006.): 745-751.

Sundblad V, Bussmann L, Chiauzzi VA, Pancholi V, Charreau EH. "Alpha-enolase: a novel autoantigen in patients with premature ovarian failure.." Clin Endocrinol (Oxf). Vol. 65, no. 6. (December 2006.): 745-751.

Jin H, Pancholi V. "Identification and biochemical characterization of a eukaryotic-type serine/threonine kinase and its cognate phosphatase in Streptococcus pyogenes: their biological functions and substrate identification.." J Mol Biol. Vol. 357, no. 5. (April 2006.): 1351-1372.

Panmanee W, Gomez F, Witte D, Pancholi V, Britigan BE, Hassett DJ. "The peptidoglycan-associated lipoprotein OprL helps protect a Pseudomonas aeruginosa mutant devoid of the transactivator OxyR from hydrogen peroxide-mediated killing during planktonic and biofilm culture.." J Bacteriol. Vol. 190, no. 10. (May 2008.): 3658-3669.

Panmanee W, Gomez F, Witte D, Pancholi V, Britigan BE, Hassett DJ. "The peptidoglycan-associated lipoprotein OprL helps protect a Pseudomonas aeruginosa mutant devoid of the transactivator OxyR from hydrogen peroxide-mediated killing during planktonic and biofilm culture." JOURNAL OF BACTERIOLOGY. Vol. 190, no. 10. (May 2008.): 3658-3669.

Sha J, Erova TE, Alyea RA, Wang S, Olano JP, Pancholi V, Chopra AK. "Surface-expressed enolase contributes to the pathogenesis of clinical isolate SSU of Aeromonas hydrophila." JOURNAL OF BACTERIOLOGY. Vol. 191, no. 9. (May 2009.): 3095-3107.

Boleij A, Schaeps RM, de Kleijn S, Hermans PW, Glaser P, Pancholi V, Swinkels DW, Tjalsma H. "Surface-exposed histone-like protein a modulates adherence of Streptococcus gallolyticus to colon adenocarcinoma cells." Infect Immun. Vol. 77, no. 12. (December 2009.): 5519-5527.

Cork AJ, Jergic S, Hammerschmidt S, Kobe B, Pancholi V, Benesch JL, Robinson CV, Dixon NE, Aquilina JA, Walker MJ. "Defining the structural basis of human plasminogen binding by streptococcal surface enolase." J Biol Chem. Vol. 284, no. 25. (June 2009.): 17129-17137.

Boleij A, Schaeps RJ, de Kleijn S, Hermans PW, Glaser P, Pancholi V, Swinkels DW, Tjalsma H. "Surface-exposed histone-like protein A modulates adherence of Streptococcus gallolyticus to colon adenocarcinoma cells." INFECTION AND IMMUNITY. Vol. 77, no. 12. (December 2009.): 5519-5527.

Beltramini Am, Mukhopadhyay CD, Pancholi V. "Modulation of cell wall structure and antimicrobial susceptibility by a Staphylococcus aureus eukaryote-like serine/threonine kinase and phosphatase." INFECTION AND IMMUNITY. Vol. 77, no. 4. (April 2009.): 1406-1416.

Beltramini AM, Mukhopadyay CD, Pancholi V. "Modulation of cell wall structure and antimicrobial susceptibility by a Staphylococcus aureus eukaryotic-like serine/threonine kinase and phosphatase." Infect Immun. Vol. 77, no. 4. (April 2009.): 1406-1416.

Cork AJ, Jergic S, Hammerschmidt S, Kobe B, Pancholi V, Benesch JP, Robinson CV, Dixon NE, Aquilina JA, Walker MJ. "Defining the structural basis of human plasminogen binding by Streptococcal surface enolase." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 284, no. 25. (June 2009.): 17129-17137.

Karbassi F, Quiros V, Pancholi V, Kornblatt MJ. "Dissociation of the octameric enolase from S. Pyogenes - One interface stabilizes another." PLOS ONE. Vol. 5, no. 1. (January 2010.): e8810-.

Karbassi F, Quiros V, Pancholi V, Kornblatt MJ. "Dissociation of the octameric enolase from S. Pyogenes -- one interface stabilizes another." PLoS One. Vol. 5, no. 1. (January 2010.): e8810-.

Pancholi V, Boel G, Jin H. "Streptococcus pyogenes Ser/Thr kinase-regulated cell wall hydrolase is a cell division plane-recognizing and chain-forming virulence factor." J Biol Chem. Vol. 285, no. 40. (October 2010.): 30861-30874.

Pancholi V, Boel G, Jin H. "Streptococcus pyogenes ser/thr kinase-regulated cell wall hydrolase is a cell division plane-recognizing and chain-forming virulence factor." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 285, no. 40. (October 2010.): 30861-30874.

Agarwal S, Agarwal S, Pancholi P, Pancholi V. "Role of serine/threonine phosphatase (SP-STP) in Streptococcus pyogenes physiology and virulence." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 286, no. 48. (December 2011.): 41368-41380.

Jin H, Agarwal S, Agarwal S, Pancholi V. "Surface export of GAPDH/SDH, a glycolytic enzyme, is essential for Streptococcus pyogenes virulence." MBIO. Vol. 2, no. 3. (May 2011.): e00068-.

Agarwal S, Agarwal S, Pancholi P, Pancholi V. "Role of Serine/threonine phosphatase (Sp-STP) in Streptococcus pyogenes physiology and virulence." J Biol Chem. Vol. 286, no. November. (September 2011.): 41368-41380.

Jin H, Agarwal S, Agarwal S, Pancholi V. "Surface export of GAPDH/SDH, a glycolytic enzyme, is essential for Streptococcus pyogenes virulence." MBio. Vol. 2, no. 3. (May 2011.): e00068-11.

Agarwal S, Agarwal S, Jin H, Pancholi P, Pancholi V. "Serine/threonine phosphatase (SP-STP), secreted from Streptococcus pyogenes, is a pro-apoptotic protein." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 287, no. 12. (March 2012.): 9147-9167.

Agarwal S, Agarwal S, Pancholi P, Pancholi V. "Strain-specific regulatory role of eukaryote-like serine/threonine phosphatase in pneumococcal adherence." INFECTION AND IMMUNITY. Vol. 80, no. 4. (April 2012.): 1361-1372.

Agarwal, S., Agarwal,S., Pancholi, P., Pancholi, V. "Strain-specific regulatory role of eukaryote-like serine/threonine phosphatase(PhpP) in pneumococcal adherence." Infect. Immun.. (February 2012.): -.

Agarwal,S., Agarwal,S.Jin, H.,Pancholi,P., Pancholi, V.. "Serine/threonine phosphatase (SP-STP),secreted from Streptococcus pyogenes, is a proapoptotic protein." J Biol Chem. (January 2012.): -.

 

Inventions and Patents

Pancholi V, Fischetti VA. Need to complete. "Bacterial plasmin binding protein and methods of use thereof.." Issued 1996, (patent granted), and Patent No. 6,190,659

Patricia Ryan; Vijay Pancholi; Vincent Fischetti. Need to complete. "Group A streptococcal bind to mucin and human pharyngeal cells through a sialic acid-containing receptor.." Issued 2002, (patent granted), and Patent No. 10,233,074

Lee,Sung; Pancholi,Vijay; Fischetti,Vincent,A. Need to complete. "Glycosylated LPXTGases and uses thereof." filed 2003, (patent pending), and Application No. 10677097

Fischetti VA, Pancholi V. need to complete. "Methods of screening inhibitors of the enzymes which cleave the anchor of surface proteins from gram positive bacteria.." Issued 1997, (patent granted), and Patent No. 5,698,763

 

Presentations

"Cell-to-cell signaling between group A streptococci and pharyngeal cells: Role of streptococcal dehydrogenase." Presented at The 13th Lancefield International Symposium on Streptococci and Streptococcal Diseases, Paris, FR|FRA. (January 1996)

"Group A streptococcal-mediated signal transduction in human pharyngeal cells." Presented at The 98th ASM General Meeting, Atlanta, GA. (January 1998)

"A novel class of streptococcal surface proteins: Their roles in group A streptococcal diseases." Oklahoma City, OK. (February 1999)

"A novel class of streptococcal surface proteins: Their roles in host cell signaling and apoptosis." Stony Brook, NY. (June 1999)

"Role of a novel class of group A streptococcal surface proteins in host cell signaling and apoptosis." Galveston, TX. (October 1999)

"Role of a novel class of streptococcal surface proteins in host cell signaling and apoptosis." New Orleans, LA. (April 2000)

"Role of a novel class of streptococcal surface proteins in host cell signaling and apoptosis." Hamilton, MT. (June 2000)

"A novel class of microbial surface proteins: Their role in streptococcal diseases." Storrs, CT. (December 2000)

"Role of a novel class of streptococcal surface proteins in host cell signaling and apoptosis." Presented at Academic Session Inauguration Lecture, Washington, DC. (January 2000)

"Role of a novel class of streptococcal surface proteins in host cell signaling and apoptosis." Newark, NJ. (February 2000)

"A novel class of microbial surface proteins: Their roles in group A streptococci-mediated host cell signaling and apoptosis." New York, NY. (October 2000)

"A novel class of microbial surface proteins: Their role in streptococcal diseases." Riverside, CA. (August 2000)

"Old proteins with new faces: Their roles in group A streptococci-mediated host cell signaling and apoptosis." Presented at Distinguished Lecture Series, San Antonio, TX. (February 2001)

"A novel class of microbial surface proteins: Their role in streptococcal-mediated host cell signaling and apoptosis." Baltimore, MD. (February 2001)

"A novel class of microbial surface proteins: Their role in streptococcal-mediated host cell signaling and apoptosis." Lawrence, KS. (January 2001)

"Elucidation of the impact of molecular interactions between streptococcal enolase (SEN) and human pharyngeal cells.." Presented at The XV Lancefield International Symposium on Streptococci and Streptococcal Diseases, Goa, IN|IND. (October 2002)

"Old proteins with new faces: Their roles in group A-streptococci-mediated host cell signaling and apoptosis." Braunschweig, DE|DEU. (February 2002)

"A novel class of microbial surface proteins: Their role in streptococcal-mediated host cell signaling and apoptosis." New Delhi, IN|IND. (February 2002)

"Old protein with new faces: Their roles in group A streptococcal pathogenesis." Albany, NY. (March 2003)

"Pathogen-host interaction and cross-talk between group A streptococci and human pharyngeal cells: Role of a novel class of microbial surface proteins." Washington, DC. (March 2004)

"Pathogen-host interaction and communication between Group A streptococci and human pharyngeal cells: Role of a novel class of microbial surface proteins." Rochester, NY. (April 2004)

"Emerging roles of a novel eukaryotic-type signaling system of group A streptococcus in transcriptional regulation and pathogenesis." Columbus, OH. (May 2005)

"Emerging roles of eukaryotic-type serine threonine kinase and phosphatase in group A streptococcal pathogenesis." Syracuse, NY. (February 2005)

"Eukaryotic-type serine/threonine kinases of gram-positive bacterial pathogens, a novel class of global regulators and potential drug targets for the biofilm-forming MDR gram-positive pathogens." Cleveland, OH. (September 2006)

"Global regulatory role of a eukaryotic-type serine/threonine kinase of Streptococcus pyogenes." Presented at The XVII Lancefield International Symposium on Streptococci and Streptococcal Diseases, Porto Heli, GR|GRC. (June 2008)

"A novel paradigm of regulation of the two-component regulatory systems by a eukaryotic-type streptococcus pyogenes serine/threonine kinase." Pullman, WA. (August 2008)

"A novel paradigm of regulation of the virulence controlling TCRS by eukaryotic-type S. pyogenes Ser/Thr kinase." Presented at The 2nd International Conference on Gram-Positive Pathogens, Omaha, NE. (October 2008)

 

Professional Activities

2006 - present Grant agency of the Academy of Sciences of the Czech Republic.
2006 - present European Research Area (ERA)-net PathoGenomics.
2007 - present Biotechnology and Biological Sciences Research Council (BBSRC).
2012 - present American Heart Association.