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Stefan Niewiesk, DVM, PhD


Staff photo

1900 Coffey Rd
Columbus, OH 43210

Phone: (614) 688-3605

Email: niewiesk.1@osu.edu

 

Current OSU Appointment

Professor, Veterinary Biosciences

 

Advising Narrative

2010 Mayers Summer Research Scholarship, OSU

(Amy Levinsky, Undergraduate Student)



2011 Poster presentation at the Denman Research Forum at OSU

Noteworthy Graduate Narrative

Mary Carsillo: 3 publications (first author), 1 publication (co-author)

Cecilia Parrula: 2 publications, 1 manuscript submitted (first author)

Dhohyung Kim: 2 publications, 1 manuscript submitted, 1 manuscript in preparation (first author), 1 publication (co-author)



2007

ACVP travel award to the Annual Meeting of the American College of Veterinary Pathology

November 2007, Savannah

(Mary Carsillo, PhD student)



NIH Loan Repayment award

(Mary Carsillo, PhD student)



2008

Poster award (1st place)

College of Veterinary Medicine Research Day

(Mary Carsillo, PhD student)



International Scholar Award from OSU

(Cecilia Parrula, PhD student)



Identification of measles virus receptors in the cotton rat model

T32 NRSA Institutional Training Grant, “Interdisciplinary Study of the Microbe-Host Interface”

(Thomas Carsillo, Postdoctoral Fellow)



2009

Special Emphasis Research Career Award (K01) from the National Institute of Health (declined in favor of industry position)

(Mary Carsillo, PhD student)



Poster award (1st place)

Measles virotherapy in combination with HSP72 expression in a mouse model of ATL.

The 11th Annual Comprehensive Cancer Center Scientific Meeting, Columbus

(Cecilia Parrula, PhD student)



2010

Poster award (1st place) in the category “Immunology and Infectious Diseases”.

Advances in Veterinary Medicine Research Day

(Dhohyung Kim, PhD student)



2011

Poster award (1st place) in the category “Immunology and Infectious Diseases”.

Advances in Veterinary Medicine Research Day

(Dhohyung Kim, PhD student)



Poster award (1st place), Travel Grant

Retreat of the Center of Microbial Interface Biology, OSU

(Dhohyung Kim, PhD student)



Distinguished Graduate Publication Award (2nd place)

VBS Graduate Student Seminar and Publication Award, Department of Veterinary Biosciences, OSU

(Dhohyung Kim, PhD student)



Stipend from the C. Glenn Barber Fund, College of Veterinary Medicine

(Dhohyung Kim, PhD student)

Certifications

1995 - present Board certified in Veterinary Microbiology: LTK Bayern Germany
1999 - present Board certified in Laboratory Animal Medicine: LTK Bayern Germany
2002 - present Board certified in Laboratory Animal Medicine: European College of Laboratory Animal Medicine
 

Chapters in Books

Stefan Niewiesk. "Current animal models: Cotton rat." In Measles Virus. Vol. 330. Edited by Griffin, Oldstone. 89-110. Berlin Heidelberg: Springer Verlag, January 2009.

Stefan Niewiesk and Michael Oglesbee. "Paramyxoviridae, Filoviridae and Bornaviruses." In Veterinary Microbiology. Edited by D. S. McVeigh et al.. -.

 

Degrees

1988 D.V.M., Tieraerztliche Hochschule Hannover

1991 Ph.D., Tieraerztliche Hochschule Hannover

2000 None Indicated, University of Wuerzburg

 

Editorial Activities

2003 - present Journal of General Virology, Journal of Virology, Acta Neuropathologica, Vaccine, Nature Medicine, Laboratory Animals, Journal of Clinical Microbiology, International Journal of Medical Microbiology, Clinical and Diagnostic Laboratory Immunology, Journal of Cytokine and Interferon Research, The Journal of Veterinary Medical Science, Virus Genes, European Journal of Immunology, Plos One, Journal of Virology, Human Immunology, Aids Research and Retroviruses, Virology, Journal of Vet. Medicine
 

Honors

1983 - 1988 Undergraduate Award. Dr. Bert Boehmer.
1989 - 1991 Graduate Award. Prof. Dr. V. ter Meulen.
1992 - 1994 Postdoctoral Fellowship Award for Infectious Diseases. Prof. Dr. V. ter Meulen.
2012 - present Pfizer Animal Health Award for Research Excellence. Pfizer Animal Health.
2014 - 2015 CIC Academic Leadership Program Fellow. Provost.
 

Journal Articles

Bankamp,B; Brinckmann,U,G; Reich,A; Niewiesk,S; ter Meulen,V; Liebert,U,G. "Measles virus nucleocapsid protein protects rats from encephalitis." JOURNAL OF VIROLOGY. Vol. 65, no. 4. (April 1991.): 1695-1700.

Reich,A; Erlwein,O; Niewiesk,S; ter Meulen,V; Liebert,U,G. "CD4+ T-cells control measles virus infection of the central nervous system." IMMUNOLOGY. Vol. 76, no. 2. (June 1992.): 185-191.

Niewiesk,S; Brinckmann,U; Bankamp,B; Sirak,S; Liebert,U,G; ter Meulen,V. "Susceptibility to measles virus-induced encephalitits in mice correlates with impaired antigen presentation to cytotoxic T lymphocytes." JOURNAL OF VIROLOGY. Vol. 67, no. 1. (January 1993.): 75-81.

Daenke,S; Parker,C,E; Niewiesk,S; Newsomdavis,J; Nightingale,S; Bangham,C,RM. "Spastic paraparesis in a patient carrying defective human T-cell leukemia virus type I (HTLV-I) provirus sequences but lacking a humoral or cytotoxic T-cell responses to HTLV-I." JOURNAL OF INFECTIOUS DISEASES. Vol. 169, no. 4. (April 1994.): 941-943.

Niewiesk,S; Daenke,S; Parker,C,E; Taylor,G; Weber,J; Nightingale,S; Bangham,C,RM. "The transactivator gene of human T-cell leukemia virus type I is more variable within and between healthy carriers than patients with tropical spastic paraparesis." JOURNAL OF VIROLOGY. Vol. 68, no. 10. (October 1994.): 6778-6781.

Niewiesk,S; Daenke,S; Parker,C,E; Taylor,G; Weber,J; Nightingale,S; Bangham,C,RM. "Naturally occurring variants of human T-cell leukemia virus type I Tax protein impair its recognition by cytotoxic T-lymphocytes and the transactivation function of Tax." JOURNAL OF VIROLOGY. Vol. 69, no. 4. (April 1995.): 2649-2653.

Niewiesk,S; Bangham,C,RM. "Evolution in a chronic RNA virus infection: Selection on HTLV-I tax protein differs between healthy carriers and patients with tropical spastic paraparesis." JOURNAL OF MOLECULAR EVOLUTION. Vol. 42, no. 4. (April 1996.): 452-458.

Niewiesk,S; Eisenhuth,I; Fooks,A; CLEGG,J,CS; Schnorr,J,J; Schneider-Schaulies,S; ter Meulen,V. "Measles virus-induced immune suppression in the cotton rat (Sigmodon hispidus) model depends on viral glycoproteins." JOURNAL OF VIROLOGY. Vol. 71, no. 10. (October 1997.): 7214-7219.

Niewiesk,S; Voelp,F; ter Meulen,V. "A maintenance and handling device for cotton rats (Sigmodon hispidus)." LAB ANIMAL. Vol. 26, no. 7. (July 1997.): 32-33.

Schmidt,M; Niewiesk,S; Heeney,J; Aguzzi,A; Rethwilm,A. "Mouse model to study the replication of primate foamy viruses." JOURNAL OF GENERAL VIROLOGY. Vol. 78, (August 1997.): 1929-1933.

Smith,R,ET; Niewiesk,S; Booth,S; Bangham,C,RM; Daenke,S. "Functional conservation of HTLV-1 rex balances the immune pressure for sequence variation in the Rex gene." VIROLOGY. Vol. 237, no. 2. (October 1997.): 397-403.

Niewiesk,S; Schneider-Schaulies,J; Ohnimus,H; Jassoy,C; Schneider-Schaulies,S; Diamond,L; Logan,J,S; ter Meulen,V. "CD46 expression does not overcome the intracellular block of measles virus replication in transgenic rats." JOURNAL OF VIROLOGY. Vol. 71, no. 10. (October 1997.): 7969-7973.

Fischer,N; Enssle,J; Muller,J; Rethwilm,A; Niewiesk,S. "Characterization of human foamy virus proteins expressed by recombinant vaccinia viruses." AIDS RESEARCH AND HUMAN RETROVIRUSES. Vol. 13, no. 6. (April 1997.): 517-521.

Neumeister,C; Niewiesk,S. "Recognition of measles virus-infected cells by CD8(+) T cells depends on the H-2 molecule." JOURNAL OF GENERAL VIROLOGY. Vol. 79, (November 1998.): 2583-2591.

Tober,C; Seufert,M; Schneider,H; Billeter,M,A; Johnston,I,CD; Niewiesk,S; ter Meulen,V; Schneider-Schaulies,S. "Expression of measles virus V protein is associated with pathogenicity and control of viral RNA synthesis." JOURNAL OF VIROLOGY. Vol. 72, no. 10. (October 1998.): 8124-8132.

Fooks,A,R; Jeevarajah,D; Lee,J; Warnes,A; Niewiesk,S; ter Meulen,V; Stephenson,J,R; Clegg,J,CS. "Oral or parenteral administration of replication-deficient adenoviruses expressing the measles virus haemagglutinin and fusion proteins: protective immune responses in rodents." JOURNAL OF GENERAL VIROLOGY. Vol. 79, (May 1998.): 1027-1031.

Niewiesk,S; Ohnimus,H; Schnorr,J,J; Gotzelmann,M; Schneider-Schaulies,S; Jassoy,C; ter Meulen,V. "Measles virus-induced immunosuppression in cotton rats is associated with cell cycle retardation in uninfected lymphocytes." JOURNAL OF GENERAL VIROLOGY. Vol. 80, (August 1999.): 2023-2029.

Schneider-Schaulies,J; Niewiesk,S; Schneider-Schaulies,S; ter Meulen,V. "Measles virus in the CNS: the role of viral and host factors for the establishment and maintenance of a persistent infection." JOURNAL OF NEUROVIROLOGY. Vol. 5, no. 6. (December 1999.): 613-622.

Niewiesk,S; Germann,P,G. "Development of neutralizing antibodies correlates with resolution of interstitial pneumonia after measles virus infection in cotton rats." JOURNAL OF EXPERIMENTAL ANIMAL SCIENCE. Vol. 40, no. 4. (January 2000.): 201-210.

Niewiesk,S; Gotzelmann,M; ter Meulen,V. "Selective in vivo suppression of T lymphocyte responses in experimental measles virus infection." PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Vol. 97, no. 8. (April 2000.): 4251-4255.

Spreng,S; Gentschev,I; Goebel,W; Weidinger,G; ter Meulen,V; Niewiesk,S. "Salmonella vaccines secreting measles virus epitopes induce protective immune responses against measles virus encephalitis." MICROBES AND INFECTION. Vol. 2, no. 14. (November 2000.): 1687-1692.

Schlereth,B; Rose,J,K; Buonocore,L; ter Meulen,V; Niewiesk,S. "Successful vaccine-induced seroconversion by single-dose immunization in the presence of measles virus-specific maternal antibodies." JOURNAL OF VIROLOGY. Vol. 74, no. 10. (May 2000.): 4652-4657.

Schlereth,B; Germann,P,G; ter Meulen,V; Niewiesk,S. "DNA vaccination with both the haemagglutinin and fusion proteins but not the nucleocapsid protein protects against experimental measles virus infection." JOURNAL OF GENERAL VIROLOGY. Vol. 81, no. Pt 5. (May 2000.): 1321-1325.

Nanan,R; Rauch,A; Kampgen,E; Niewiesk,S; Kreth,H,W. "A novel sensitive approach for frequency analysis of measles virus-specific memory T-lymphocytes in healthy adults with a childhood history of natural measles." JOURNAL OF GENERAL VIROLOGY. Vol. 81, no. Pt 5. (May 2000.): 1313-1319.

Weidinger,G; Czub,S; Neumeister,C; Harriott,P; ter Meulen,V; Niewiesk,S. "Role of CD4(+) and CD8(+) T cells in the prevention of measles virus-induced encephalitis in mice." JOURNAL OF GENERAL VIROLOGY. Vol. 81, no. Pt 11. (November 2000.): 2707-2713.

Moeller,K; Duffy,I; Duprex,P; Rima,B; Beschorner,R; Fauser,S; Meyermann,R; Niewiesk,S; ter Meulen,V; Schneider-Schaulies,J. "Recombinant measles viruses expressing altered hemagglutinin (H) genes: Functional separation of mutations determining H antibody escape from neurovirulence." JOURNAL OF VIROLOGY. Vol. 75, no. 16. (August 2001.): 7612-7620.

Ohgimoto,S; Ohgimoto,K; Niewiesk,S; Klagge,I,M; Pfeuffer,J; Johnston,I,CD; Schneider-Schaulies,J; Weidmann,A; ter Meulen,V; Schneider-Schaulies,S. "The haemagglutinin protein is an important determinant of measles virus tropism for dendritic cells in vitro." JOURNAL OF GENERAL VIROLOGY. Vol. 82, no. Pt 8. (August 2001.): 1835-1844.

Weidinger,G; Ohlmann,M; Schlereth,B; Sutter,G; Niewiesk,S. "Vaccination with recombinant modified vaccinia virus Ankara protects against measles virus infection in the mouse and cotton rat model." VACCINE. Vol. 19, no. 20-22. (April 2001.): 2764-2768.

Weidinger,G; Henning,G; ter Meulen,V; Niewiesk,S. "Inhibition of major histocompatibility complex class II-dependent antigen presentation by neutralization of gamma interferon leads to breakdown of resistance against measles virus-induced encephalitis." JOURNAL OF VIROLOGY. Vol. 75, no. 7. (April 2001.): 3059-3065.

Moriabadi,N,F; Niewiesk,S; Kruse,N; Jung,S; Weissbrich,B; ter Meulen,V; Toyka,K,V; Rieckmann,P. "Influenza vaccination in MS - Absence of T-cell response against white matter proteins." NEUROLOGY. Vol. 56, no. 7. (April 2001.): 938-943.

Schneider-Schaulies,S; Niewiesk,S; Schneider-Schaulies,J; ter Meulen,V. "Measles virus induced immunosuppression: targets and effector mechanisms.." CURRENT MOLECULAR MEDICINE. Vol. 1, no. 2. (May 2001.): 163-181.

Neumeister,C; Nanan,R; Cornu,T,I; Luder,C,GK; ter Meulen,V; Naim,H; Niewiesk,S. "Measles virus and canine distemper virus target proteins into a TAP-independent MHC class I-restricted antigen-processing pathway." JOURNAL OF GENERAL VIROLOGY. Vol. 82, no. Pt 2. (February 2001.): 441-447.

Avota,E; Avots,A; Niewiesk,S; Kane,L,P; Bommhardt,U; ter Meulen,V; Schneider-Schaulies,S. "Disruption of Akt kinase activation is important for immunosuppression induced by measles virus." NATURE MEDICINE. Vol. 7, no. 6. (June 2001.): 725-731.

Niewiesk,S; Prince,G. "Diversifying animal models: the use of hispid cotton rats (Sigmodon hispidus) in infectious diseases." LABORATORY ANIMALS. Vol. 36, no. 4. (October 2002.): 357-372.

Schlereth,B; Buonocore,L; Tietz,A; ter Meulen,V; Rose,J,K; Niewiesk,S. "Successful mucosal immunization of cotton rats in the presence of measles virus-specific antibodies depends on degree of attenuation of vaccine vector and virus dose." JOURNAL OF GENERAL VIROLOGY. Vol. 84, no. Pt 8. (August 2003.): 2145-2151.

Pfeuffer,J; Puschel,K; ter Meulen,V; Schneider-Schaulies,J; Niewiesk,S. "Extent of measles virus spread and immune suppression differentiates between wild-type and vaccine strains in the cotton rat model (Sigmodon hispidus)." JOURNAL OF VIROLOGY. Vol. 77, no. 1. (January 2003.): 150-158.

Gundel,I; Weidinger,G; ter Meulen,V; Heesemann,A; Russmann,H; Niewiesk,S. "Oral immunization with recombinant Yersinia enterocolitica expressing a measles virus CD4 T cell epitope protects against measles virus-induced encephalitis." JOURNAL OF GENERAL VIROLOGY. Vol. 84, no. Pt 4. (April 2003.): 775-779.

Moll,M; Pfeuffer,J; Klenk,H,D; Niewiesk,S; Maisner,A. "Polarized glycoprotein targeting affects the spread of measles virus in vitro and in vivo." JOURNAL OF GENERAL VIROLOGY. Vol. 85, no. Pt 4. (April 2004.): 1019-1027.

Thomas,C,A; Carsillo,M; Niewiesk,S; Vasconcelos,D; Oglesbee,M. "Hyperthermic pre-conditioning promotes measles virus clearance from brain in a mouse model of persistent infection." BRAIN RESEARCH. Vol. 1004, no. 1-2. (April 2004.): 73-82.

Streif,S; Pueschel,K; Tietz,A; Blanco,J; ter Meulen,V; Niewiesk,S. "Effector CD8(+) T cells are suppressed by measles virus infection during delayed type hypersensitivity reaction." VIRAL IMMUNOLOGY. Vol. 17, no. 4. (January 2004.): 604-608.

Richter,B,WM; Onuska,J,M; Niewiesk,S; Prince,G,A; Eichelberger,M,C. "Antigen-dependent proliferation and cytokine induction in respiratory syncytial virus-infected cotton rats reflect the presence of effector-memory T cells." VIROLOGY. Vol. 337, no. 1. (June 2005.): 102-110.

Mahler,M; Heidtmann,W; Niewiesk,S; Gruber,A; Fossmark,R; Beil,W; Hedrich,H; Wagner,S. "Experimental Helicobacter pylori infection induces antral-predominant, chronic active gastritis in hispid cotton rats (Sigmodon hispidus)." HELICOBACTER. Vol. 10, no. 4. (August 2005.): 332-344.

Luhrmann,A; Tschernig,T; Pabst,R; Niewiesk,S. "Improved intranasal immunization with live-attenuated measles virus after co-inoculation of the lipopeptide MALP-2." VACCINE. Vol. 23, no. 39. (September 2005.): 4721-4726.

Santibanez,S; Niewiesk,S; Heider,A; Schneider-Schaulies,J; Berbers,G,AM; Zimmermann,A; Halenius,A; Wolbert,A; Deitemeier,I; Tischer,A; Hengel,H. "Probing neutralizing-anti body responses against emerging measles viruses (MVs): immune selection of MV by H protein-specific antibodies?." JOURNAL OF GENERAL VIROLOGY. Vol. 86, no. Pt 2. (February 2005.): 365-374.

Schubert,S; Moeller-Ehrlich,K; Singethan,K; Wiese,S; Duprex,W,P; Rima,B,K; Niewiesk,S; Schneider-Schaulies,J. "A mouse model of persistent brain infection with recombinant Measles virus." JOURNAL OF GENERAL VIROLOGY. Vol. 87, no. Pt 7. (July 2006.): 2011-2019.

Carsillo,Thomas; Traylor,Zachary; Choi,Changsun; Niewiesk,Stefan; Oglesbee,Michael. "hsp72, a host determinant of measles virus neurovirulence." JOURNAL OF VIROLOGY. Vol. 80, no. 22. (November 2006.): 11031-11039.

Carsillo,T; Zhang,X,S; Vasconcelos,D; Niewiesk,S; Oglesbee,M. "A single codon in the nucleocapsid protein C terminus contributes to in vitro and in vivo fitness of Edmonston measles virus." JOURNAL OF VIROLOGY. Vol. 80, no. 6. (March 2006.): 2904-2912.

Moeller-Ehrlich,K; Ludlow,M; Beschorner,R; Meyermann,R; Rima,B,K; Duprex,W,P; Niewiesk,S; Schneider-Schaulies,J. "Two functionally linked amino acids in the stem 2 region of measles virus haemagglutinin determine infectivity and virulence in the rodent central nervous system." JOURNAL OF GENERAL VIROLOGY. Vol. 88, (November 2007.): 3112-3120.

Hassantoufighi,A; Oglesbee,M; Richter,B,WM; Prince,G,A; Hemming,V; Niewiesk,S; Eichelberger,M,C. "Respiratory syncytial virus replication is prolonged by a concomitant allergic response." CLINICAL AND EXPERIMENTAL IMMUNOLOGY. Vol. 148, no. 2. (May 2007.): 218-229.

Pueschel,Karen; Tietz,Annette; Carsillo,Mary; Steward,Michael; Niewiesk,Stefan. "Measles virus-specific CD4 T-Cell activity does not correlate with protection against lung infection or viral clearance." JOURNAL OF VIROLOGY. Vol. 81, no. 16. (August 2007.): 8571-8578.

Carsillo,Thomas; Carsillo,Mary; Traylor,Zachary; Rajala-Schultz,Paeivi; Popovich,Phillip; Niewiesk,Stefan; Oglesbee,Michael. "Major Histocompatibility Complex Haplotype Determines hsp70-Dependent Protection against Measles Virus Neurovirulence." JOURNAL OF VIROLOGY. Vol. 83, no. 11. (June 2009.): 5544-5555.

Niewiesk,S. "Current Animal Models: Cotton Rat Animal Model." MEASLES: PATHOGENESIS AND CONTROL. Vol. 330, (January 2009.): 89-110.

Carsillo,Mary; Klapproth,Kay; Niewiesk,Stefan. "Cytokine Imbalance after Measles Virus Infection Has No Correlation with Immune Suppression." JOURNAL OF VIROLOGY. Vol. 83, (July 2009.): 7244-7251.

Parrula,C; Zimmerman,B; Nadella,P; Shu,S; Rosol,T; Fernandez,S; Lairmore,M; Niewiesk,S. "Expression of Tumor Invasion Factors Determines Systemic Engraftment and Induction of Humoral Hypercalcemia in a Mouse Model of Adult T-cell Leukemia." VETERINARY PATHOLOGY. Vol. 46, (September 2009.): 1003-1014.

Carsillo,Mary; Kutala,Vijay,Kumar; Puschel,Karen; Blanco,Jorge; Kuppusamy,Periannan; Niewiesk,Stefan. "Nitric oxide production and nitric oxide synthase type 2 expression by cotton rat (Sigmodon hispidus) macrophages reflect the same pattern as human macrophages." DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. Vol. 33, (January 2009.): 718-724.

Rauch,Dan; Gross,Shimon; Harding,John; Bokhari,Sirosh; Niewiesk,Stefan; Lairmore,Michael; Piwnica-Worms,David; Ratner,Lee. "T-cell activation promotes tumorigenesis in inflammation-associated cancer." RETROVIROLOGY. Vol. 6, (December 2009.): 116-.

Palermo,Laura,M; Porotto,Matteo; Yokoyama,Christine,C; Palmer,Samantha,G; Mungall,Bruce,A; Greengard,Olga; Niewiesk,Stefan; Moscona,Anne. "Human Parainfluenza Virus Infection of the Airway Epithelium: Viral Hemagglutinin-Neuraminidase Regulates Fusion Protein Activation and Modulates Infectivity." JOURNAL OF VIROLOGY. Vol. 83, (July 2009.): 6900-6908.

Rauch,Dan; Gross,Shimon; Harding,John; Niewiesk,Stefan; Lairmore,Michael; Piwnica-Worms,David; Ratner,Lee. "Imaging spontaneous tumorigenesis: inflammation precedes development of peripheral NK tumors." BLOOD. Vol. 113, (February 2009.): 1493-1500.

Runkler,Nicole; Dietzel,Erik; Carsillo,Mary; Niewiesk,Stefan; Maisner,Andrea. "Sorting signals in the measles virus wild-type glycoproteins differently influence virus spread in polarized epithelia and lymphocytes." JOURNAL OF GENERAL VIROLOGY. Vol. 90, (October 2009.): 2474-2482.

Moscona,Anne; Porotto,Matteo; Palmer,Samantha; Tai,Caroline; Aschenbrenner,Lori; Triana-Baltzer,Gallen; Li,Qi-Xiang; Wurtman,David; Niewiesk,Stefan; Fang,Fang. "A Recombinant Sialidase Fusion Protein Effectively Inhibits Human Parainfluenza Viral Infection In Vitro and In Vivo." JOURNAL OF INFECTIOUS DISEASES. Vol. 202, (January 2010.): 234-241.

Bevin Zimmerman, Stefan Niewiesk, and Michael Lairmore. "Mouse Models of Human T Lymphotropic Virus Type-1 Associated Adult T-cell Leukemia/Lymphoma." VETERINARY PATHOLOGY. Vol. 47, (July 2010.): 677-689.

Perrone,Danielle; Bender,Scott; Niewiesk,Stefan. "A comparison of the immune responses of dogs exposed to canine distemper virus (CDV) - Differences between vaccinated and wild-type virus exposed dogs." CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE. Vol. 74, no. 3. (July 2010.): 214-217.

Rauch,Daniel,A; Hurchla,Michelle,A; Harding,John,C; Deng,Hongju; Shea,Lauren,K; Eagleton,Mark,C; Niewiesk,Stefan; Lairmore,Michael,D; Piwnica-Worms,David; Rosol,Thomas,J; Weber,Jason,D; Ratner,Lee; Weilbaecher,Katherine,N. "The ARF Tumor Suppressor Regulates Bone Remodeling and Osteosarcoma Development in Mice." PLOS ONE. Vol. 5, no. 12. (December 2010.): e15755-.

Carsillo,Mary; Kim,Dhohyung; Niewiesk,Stefan. "Role of AKT Kinase in Measles Virus Replication." JOURNAL OF VIROLOGY. Vol. 84, (February 2010.): 2180-2183.

Oglesbee,Michael; Niewiesk,Stefan. "Measles virus neurovirulence and host immunity." FUTURE VIROLOGY. Vol. 6, (January 2011.): 85-99.

Kim,Dhohyung; Martinez-Sobrido,Luis; Choi,Changsun; Petroff,Natasha; Garcia-Sastre,Adolfo; Niewiesk,Stefan; Carsillo,Thomas. "Induction of Type I Interferon Secretion through Recombinant Newcastle Disease Virus Expressing Measles Virus Hemagglutinin Stimulates Antibody Secretion in the Presence of Maternal Antibodies." JOURNAL OF VIROLOGY. Vol. 85, (January 2011.): 200-207.

Parrula,Cecilia; Fernandez,Soledad,A; Zimmerman,Bevin; Lairmore,Michael; Niewiesk,Stefan. "Measles virotherapy in a mouse model of adult T-cell leukaemia/lymphoma." JOURNAL OF GENERAL VIROLOGY. Vol. 92, (January 2011.): 1458-1466.

Kim,Dhohyung; Huey,Devra; Oglesbee,Michael; Niewiesk,Stefan. "Insights into the regulatory mechanism controlling the inhibition of vaccine-induced seroconversion by maternal antibodies." BLOOD. Vol. 117, (June 2011.): 6143-6151.

Green,M,Gia; Huey,Devra; Niewiesk,Stefan. "The cotton rat (Sigmodon hispidus) as an animal model for respiratory tract infections with human pathogens." LAB ANIMAL. Vol. 42, no. 5. (May 2013.): 170-176.

Kim,Mi,Young; Shu,Yaoling; Carsillo,Thomas; Zhang,Jianying; Yu,Lianbo; Peterson,Cornelia; Longhi,Sonia; Girod,Sarah; Niewiesk,Stefan; Oglesbee,Michael. "hsp70 and a Novel Axis of Type I Interferon-Dependent Antiviral Immunity in the Measles Virus-Infected Brain." JOURNAL OF VIROLOGY. Vol. 87, no. 2. (January 2013.): 998-1009.

Kim,Dhohyung; Niewiesk,Stefan. "Synergistic Induction of Interferon alpha through TLR-3 and TLR-9 Agonists Identifies CD21 as Interferon alpha Receptor for the B Cell Response." PLOS PATHOGENS. Vol. 9, no. 3. (March 2013.): e1003233-.

Xu,Rui; Palmer,Samantha,G; Porotto,Matteo; Palermo,Laura,M; Niewiesk,Stefan; Wilson,Ian,A; Moscona,Anne. "Interaction between the Hemagglutinin-Neuraminidase and Fusion Glycoproteins of Human Parainfluenza Virus Type III Regulates Viral Growth In Vivo." MBIO. Vol. 4, no. 5. (September 2013.): e00803-13.

Ma,Yuanmei; Duan,Yue; Wei,Yongwei; Liang,Xueya; Niewiesk,Stefan; Oglesbee,Michael; Li,Jianrong. "Heat Shock Protein 70 Enhances Mucosal Immunity against Human Norovirus When Coexpressed from a Vesicular Stomatitis Virus Vector." JOURNAL OF VIROLOGY. Vol. 88, no. 9. (May 2014.): 5122-5137.

Wei,Yongwei; Zhang,Yu; Cai,Hui; Mirza,Anne,M; Iorio,Ronald,M; Peeples,Mark,E; Niewiesk,Stefan; Lia,Jianrong. "Roles of the Putative Integrin-Binding Motif of the Human Metapneumovirus Fusion (F) Protein in Cell-Cell Fusion, Viral Infectivity, and Pathogenesis." JOURNAL OF VIROLOGY. Vol. 88, no. 8. (April 2014.): 4338-4352.

Kim,Dhohyung; Niewiesk,Stefan. "Synergistic induction of interferon a through TLR-3 and TLR-9 agonists stimulates immune responses against measles virus in neonatal cotton rats." VACCINE. Vol. 32, no. 2. (January 2014.): 265-270.

 

Presentations

"Measles virus induced immune suppression in the cotton rat model (Sigmodon hispidus)." Presented at University of Toledo Microbiology Seminar Series, University of Toledo. (February 2007)

"Cytokine imbalance after measles virus infection but no correlation with immune suppression." Presented at Annual Meeting of the American Society of Virology, Ithaca, New York. (July 2008)

"Mechanism of inhibition of vaccination by maternal antibodies." Presented at Annual Meeting of the American Society of Virology, Bozeman, Montana. (July 2010)

"Mechanism of inhibition of vaccination by maternal antibodies." Presented at Negative Strand RNA Viruses, Belfast, GB|GBR. (March 2010)

"Mechanism of inhibition of vaccination by maternal antibodies." Presented at Dangerous Liasons-Pathogens and the Immune System; Ulster Immunology Group/Irisch Society of Immunology, Belfast, GB|GBR. (September 2010)

"Mechanism of inhibition by maternal antibodies." Presented at Keystone Symposium, Immunological Mechanisms of Vaccination, Seattle, US|USA. (October 2010)

"The use of animal models for development of vaccines against biosecurity agents." Presented at Biosecurity meeting for the American Association for the Advancement of Science, Washington, DC, US|USA. (October 2011)

"Insights into the regulatory mechanism controlling the inhibition of vaccine-induced seroconversion by maternal antibodies." Presented at Measles Virus meeting at Mayo Clinic, Rochester, Minnesota. (July 2011)

"Of mice and men: evolutionary, what are the best rodent models of the human immune system for infectious diseases research?." Presented at Experimental Biology, San Diego, CA, US|USA. (May 2012)

"Immunization in the presence of maternal antibodies." Presented at Annual Meeting of the American Society of Virology, Madison, Wisconsin. (July 2012)

"Evolutionary aspects of animal model use for infectious diseases research." Presented at 12th Annual Meeting of the Safety Pharmacology Society, Phoenix, US|USA. (October 2012)

"Next generation adjuvants for single dose vaccines." Presented at TechConnectWorld, Santa Clara, US|USA. (June 2012)

"Immunisierung in der Gegenwart maternaler Antikörper." Presented at Laboratory Animal Medicine Seminar, Hannover, DE|DEU. (February 2012)

"Inhibition of vaccine responses by neutralizing antibodies." Presented at 2nd International Neonatal Maternal Immunization Symposium, Antalya, TR|TUR. (March 2013)

 

Professional Activities

2010 - present Grant Review. Italian Ministry of Health.
2011 - present Grant Review. American Heart Association, Immunology Committee.
2007 Ad hoc review. NIH, SEP "Immune Mechanisms of Viral Control"..
2008 Ad hoc reviewer. NIH, U19 "Cooperative Centers for Translational Research on Human Immunology and Biodefense".
2008 Ad hoc reviewer Virology A study section. NIH, Virology A.
2009 Grant Review. The Netherlands Organisation for Health Research and Development (ZonMw).
2009 Ad hoc reviewer. NIH, SEP ZRG1 IDM-Q (02) M – Member Conflicts in Virology.
2009 Ad hoc review. NIH, ZRG1 IDM-C (58) R - RFA09-003 Challenge Grants Panel 9.
2011 Ad hoc review. OSU Comprehensive Cancer Center Pelotonia.
2011 Ad hoc review. OSU CTTS.
2011 Ad hoc review. NIH, IDM-B (50) Study Section.
2010 - 2012 Grant Review. United States-Israel Binational Science Foundation.
2012 Ad hoc reviewer. NIH Study Section IDM-B (50).
2012 Ad hoc review. OSU PHPID.