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Sheryl Justice, PhD


Staff photo

700 Childrens Dr
Ctr for Microbial Pathogenesis
Columbus, OH 43205

Email: justice.133@osu.edu

 

Current OSU Appointment

Assistant Professor, Pediatrics

 

Research Funding

Past grant submissions: Since joining the faculty in October of 2006, I have pursued multiple lines of support for the laboratory. Three R01 applications were submitted to the NIDDK at the NIH on my primary research focus of determining the mechanisms that bacteria use to subvert the host innate immune response and cause disease (unscored). Comments from the reviewers: "This is a very productive and highly motivated investigator with great potential to succeed. This is a highly innovative proposal from a new investigator that will examine a key event in the pathogenesis of UTIs, bacterial filamentation as a UPEC defense strategy to evade phagocytosis by innate immune effector cells. The PI is well-trained and poised to become a leader in the field of UTI pathogenesis. This resubmitted grant application is from a well trained and highly accomplished young investigator with a promising future as a researcher. The ideas behind this proposal are highly innovative and the proposed approaches are also innovative." A new collaboration with Dr. Santiago Partida-Sanchez has led us into a new realm of investigation into the mechanism by which maternal UTI mediates preterm birth. Two R21 applications were submitted to the NICHD and the NAIAD(unscored). R21 reviewer comments: "This is a novel hypothesis that may provide a link between UTI and adverse pregnancy outcome and addresses an important public health problem. This is an innovative proposal that builds upon strong preliminary data. This proposal will advance our understanding of the associations among UTI and adverse pregnancy outcome, and may suggest novel treatment strategies. The role of UTI specifically in preterm birth requires more study, which makes this proposal highly significant. The strength of the proposal includes a well articulated experimental paradigm, well detailed protocols with specific outcome measures to be analyzed, use of ultrasound technology for fetal monitoring, and, most importantly, the models elected for use in this study are very appropriate for testing the stated hypothesis. In addition, several of the experiments will have well defined controls. The this application has the potential to provide some very novel and exciting data in this area." The March of Dimes has invited me to submit an application on the preterm project for a second year in a row. The response to the first application was highly favorable, and the current application is in review. March of Dimes comments: "This is a well-thought out and developed study by investigators already familiar with a mouse model of UTI to examine a potentially important cause of premature birth. It is very comprehensive, and may help determine the cellular and molecular mechanisms involved in UPEC mediated prematurity. The only major concern I have is that the model is not yet in place, but I think it is worth seeing if this model could be developed, because of its relationship to human prematurity." Current Submissions: March of Dimes, submission July 15, 2009 R01 to NIDDK, submission October 5, 2009 RO1 to NICHD, submission October 5, 2009 I have a project established with a biotechnology firm, Achaogen, to test their potential therapeutics in our mouse model for UTI. That contract is pending upon completion of production of their compounds. Future plans: I will continue to seek funding from the NIDDK, the NICHD and the March of Dimes until I acquire the equivalent of two R01 applications. I anticipate submitting at least one grant year until the equivalent of two R01 applications are secured to maintain my laboratory.

Academic Advising

2011 - 2013 Brian Becknell The Research Institute at Nationwide Children's Hospital. Graduated 2013.
2012 - 2013 Ahmad Mohamed Nationwide Children's Hospital. Graduated 2013.
2013 Chloe Williams Michigan State University College of Medicine.
 

Chapters in Books

Justice SS, Dodson KW, Chapman MR, Barnhart MM and SJ Hultgren. "Assembly of Adhesive Organelles on Gram Negative Bacteria." In Protein Secretion Pathways in Bacteria. First ed. Edited by Bauke Oudega. 207-232. New York, NY, US|USA: Kluwer Academic Publishers, January 2003.

 

Clinical Trials

Effectiveness of LoFric catheters to impove the microbial milieu in patients with neurogenic bladders

 

Conferences

Anderson,Gregory; Justice,Sheryl; Hultgren,Scott; Seed,Patrick. "Exopolysaccharide Capsule and Sialic Acid Signaling Contribute to Key Intracellular and Extracellular Pathways Used by Uropathogenic Escherichia Coli During Experimental Cystitis." In JOURNAL OF WOMENS HEALTH. (October 2008). 1251-1251.

 

Degrees

1986 B.S., University of Missouri

1994 M.S., University of Missouri

2001 Ph.D., University of Connecticut

 

Honors

1988 - 1990 Graduate Assistant Fellowship. University of Missouri.
1993 American Society for Microbiology Graduate Student Award. American Society for Microbiology.
 

Journal Articles

Stader J, Justice SS and Wei S.. "The use of hybrid proteins to isolate kinetic export intermediates." NATO ASI Series, Dynamics of Membrane Assembly Series H: Cell Biology. no. 63. (January 1992.): 256-276.

StaderJ, Justice S. "Export and trimerization pathways of maltoporin overlap in the inner membrane of Escherchia coli." Journal of Molecular Biology. Vol. 238, no. 4. (May 1994.): 555-562.

Rothfield LI, Justice SS. "Bacterial cell division: The cycle of the ring." Cell. Vol. 88, no. 5. (March 1997.): 581-584.

Rothfield L, Justice S, Garcia-Lara J. "Bacterial cell division." Annual Review of Genetics. Vol. 33, (January 1999.): 423-448.

Justice SS, Garcia-Lara J, Rothfield LI. "Cell division inhibitors SulA and MinC/MinD block septum formation at different steps in the assembly of the Escherichia coli division machinery." Molecular Microbiology. Vol. 37, no. 2. (July 2000.): 410-423.

Schilling JD, Martin SM, Hunstad DA, Patel KP, Mulvey MA, Justice SS, Lorenz RG, Hultgren SJ. "CD14-and toll-like receptor-devendent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli." Infection and Immunity. Vol. 71, no. 3. (March 2003.): 1470-1480.

Justice SS, Hung C, Theriot JA, Fletcher DA, Anderson GG, Footer MJ, Hultgren SJ. "Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis." Proceedings of the National Academy of Sciences of the United States of America. Vol. 101, no. 5. (February 2004.): 1333-1338.

Justice SS, Hunstad DA, Harper JR, Duguay AR, Pinkner JS, Bann J, Frieden C, Silhavy TJ, Hultgren SJ. "Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli." Journal of Bacteriology. Vol. 187, no. 22. (November 2005.): 7680-7686.

Hunstad DA, Justice SS, Hung CS, Lauer SR, Hultgren SJ. "Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli." Infection and Immunity. Vol. 73, no. 7. (July 2005.): 3999-4006.

Justice SS, Hunstad DA, Seed PC, Hultgren SJ. "Filamentation by Escherichia coli subverts innate defenses during urinary tract infection." Preoceedings of the National Academy of Sciences of the United States of America. Vol. 103, no. 52. (December 2006.): 19884-19889.

Justice SS, Lauer SR, Hultgren SJ, Hunstad DA. "Maturation of intracellular Escherichia coli communities requires SurA." Infection and Immunity. Vol. 74, no. 8. (August 2006.): 4793-4800.

Justice SS, Hunstad DA, Cegelski L, Hultgren SJ. "Morphological plasticity as a bacterial survival strategy." Nature Reviews Microbiology. Vol. 6, no. 2. (February 2008.): 162-168.

Anderson G, Justice S, Hultgren S, Seed P. "Exopolysaccharide capsule and sialic acid signaling contribute to key intracellular and extracellular pathways used by uropathogenic Escherichia coli furing experimental cystitis." Journal of Womens Health. Vol. 17, no. 8. (October 2008.): 1251-1251.

Li B, Smith P, Horvath Jr. DJ, Romesberg F, and Justice SS. "SOS regulatory elements are essential for UPEC pathogenesis." Microbes and Infection. Vol. 12, no. 8-9. (January 2010.): 662-668.

Hunstad,David,A; Justice,Sheryl,S. "Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli." Annual Review of Microbiology. Vol. 64, (January 2010.): 203-221.

Li B, Smith P, Horvath DJ, Romesberg FE, Justice SS. "SOS regulatory elements are essential for UPEC pathogenesis." Microbes and Infection. Vol. 12, no. 8-9. (August 2010.): 662-668.

Justice S and Hunstad D. "Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli." Annual Review Microbiology. Vol. 13, no. 64. (January 2010.): 203-221.

Anderson GG, Goller CC, Justice S, Hultgren SJ, Seed PC. "Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis." Infection and Immunity. Vol. 78, no. 3. (March 2010.): 963-975.

Spencer JD, Schwaderer AL, Dirosario JD, McHugh KM, McGillivary G, Justice SS, Carpenter AR, Baker PB, Harder J, Hains DS. "Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract." Kidney International. Vol. 80, no. 2. (July 2011.): 175-181.

Storm DW, Patel AS, Koff SA, Justice SS. "Novel management of urinary tract infections." Current Opinion in Urology. Vol. 21, no. 4. (July 2011.): 328-333.

Horvath DJ, Li B, Casper T, Partida-Sanchez S, Hunstad DA, Hultgren SJ, Justice SS. "Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli." Microbes and Infection. Vol. 13, no. 5. (May 2011.): 426-437.

Storm DW, Koff SA, Horvath Jr. DJ, Li B, and Justice SS.. "An in vitro analysis of the bactericidal activity of Escherichia coli Nissle 1917 against pediatric uropathogens.." Journal of Urology. Vol. 186, no. 4. (October 2011.): 1678-1683.

Dabdoub SM, Ray WC, Justice SS. "FIND: A new software tool and development platform for enhanced multicolor flow analysis." BMC Bioinformatics. Vol. 12, (May 2011.): 145-.

Dabdoub SM, Justice SS, Ray WC. "A dynamically masked gaussian can efficiently approximate a distance calculation for image segmentation." Software Tools and Algorithims for Biological Systems. Vol. 696, (January 2011.): 425-432.

Goodman SD, Obergfell KP, Jurcisek JA, Novotny LA, Downey JS, Ayala EA, Tjokro N, Li B, Justice SS, Bakaletz LO.. "Biofilms can be dispersed by focusing the immune system on a common family of bacterial nucleoid associated proteins." Mucosal Immunity. Vol. 6, no. 4. (November 2011.): 625-637.

Justice SS, Hunstad DA. "UPEC Hemolysin: More than Just for Making Holes." Cell Host & Microbe. Vol. 11, no. 1. (January 2012.): 4-5.

Bolton M, Horvath Jr. DJ, Li B, Cortado N, Newsom D, White P, Partida-Sanchez S, and Justice SS. "Intrauterine growth restriction is a direct consequence of localized maternal uropathogenic Escherichia coli cystitis.." PLoS One. Vol. 7, no. 3. (January 2012.): e33897-.

Vogel AR, Szelestey BR, Raffel FK, Sharpe SW, Gearinger RL, Justice SS, Mason KM. "SapF-mediated heme-iron utilization enhances persistence and coordinates biofilm architecture of Haemophilus.." Frontiers in Cellular and Infection Microbiology. Vol. 2, (January 2012.): 42-.

Horvath DJ, Dabdoub SM, Li B, VanderBrink BA, and Justice SS. "New paradigms of urinary tract infections: Implications for patient management." Indian Journal of Urology. Vol. 188, no. 1. (April 2012.): 236-241.

Partida-Sanchez S, Horvath D, Cortado H, Li B, Flano E, Justice S. "Monocyte-derived inflammatory dendritic cells expressing CX3CR1hi control urinary tract infection in mice." Journal of Immunology. Vol. 188, no. 120. (May 2012.): 25-.

Justice SS, Li B, Downey JS, Brockson ME, Ray WC, Goodman SD. "Aberrant Community Architecture and Attenuated Persistence of Uropathogenic Escherichia coli in the Absence of Individual IHF Subunits." PLoS One. Vol. 7, no. 10. (October 2012.): e48349-.

Storm DW, Patel AS, Horvath DJ, Li B, Koff SA, Justice SS. "Relationship Among Bacterial Virulence, Bladder Dysfunction, Vesicoureteral Reflux and Patterns of Urinary Tract Infection in Children." Journal of Urology. Vol. 188, no. 1. (July 2012.): 236-241.

Partida-Sanchez S, Cortado H, Horvath D, Li R, Flano E, Justice S. "Nonclassical monocyte-derived macrophages are essential for preventing pyelonephritis upon urinary tract infection in mice." Journal of Immunology. Vol. 190, no. 130. (May 2013.): 14-.

Mohamed A, Li B, Jayanthi V, Justice S. "Immunomodulatory capacity accurately predicts disease severity caused by different strains of uropathogenic Escherichia Coli." Journal of Urology. Vol. 189, no. 4. (April 2013.): E471-E472.

Szelestey BR, Heimlich DR, Raffel FK, Justice SS, Mason KM. "Haemophilus responses to nutritional immunity: epigenetic and morphological contribution to biofilm architecture, invasion, persistence and disease severity.." PLoS Pathogens. Vol. 9, no. 10. (January 2013.): e1003709-.

Spencer JD, Schwaderer AL, Eichler T, Wang H, Kline J, Justice SS, Cohen DM, Hains DS. "An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract." Kidney International. Vol. 0, no. Epub ahead of print. (October 2013.): 0-.

Becknell B, Spencer JD, Carpenter AR, Chen X, Ploeger S, Kline J, Ellsworth P, Li B, Proksch E, Schwaderer AL, Hains DS, Justice SS, McHugh KM. "Expression and antimicrobial function of Beta-defensin 1 in the lower urinary tract." Plos One. Vol. 8, no. 10. (October 2013.): e7714-.

Horvath Jr. DJ, Dabdoub SM, Li B, VanderBrink BA and Justice SS. "New paradigms of urinary tract infections: Implications for patient management." Indian Journal of Urology. -.

 

Reference Works

January 2006 Justice SS, Hunstad DA, Seed PC and Hultgren SJ."Filamentation by E. coli subverts innate defenses during urinary tract infection" .
January 2007 Horvath Jr DJ, Lee R, Partida-Sanchez S and Justice SS."Analysis of innate immune response to uropathogenic Escherichia coli in a murine cystitis model." .
January 2007 Li B, Justice SS, Hunstad DA, Seed PC, and Hultgren SJ."Filamentation by E. coli subverts innate defenses during urinary tract infection" Columbus.
January 2007 Li B and Justice SS.."Genetic tools for analyzing individual bacterial gene expression." .
January 2007 Li B and Justice SS."Subversion of innate defenses during urinary tract infection" Columbus.
January 2007 Dabdoub S, Justice SS and Ray WC."Exploiting biological coherency in classification and segmentation" .
January 2007 Dabdoub S, Justice SS and Ray WC."Exploiting biological coherence in classification and segmentation" .
January 2008 Li B and Justice SS."SOS regulatory elements are essential for UPEC pathogenesis" Columbus.
January 2008 Dabdoub SM, Justice SS, and Ray WC."Exploiting biological coherency in classification and segmentation" Columbus.
January 2008 Li B, Smith P, Horvath Jr. DJ, Romesberg FE, and Justice SS."SOS regulatory elements are essential for UPEC pathogenesis" Columbus.
January 2008 Horvath Jr. DJ, Li B, Partida-Sanchez S, and Justice SS."Characterization of kinetics of innate immune response to uropathogenic Escherichia coli in a murine cystitis model" Columbus.
January 2008 Horvath Jr. DJ, Li B, Partida-Sanchez S, and Justice SS."Mucosal immune responses in genitourinary tissues following a urinary tract infection" Columbus.
January 2008 Horvath Hr. DJ, Li B, Partida-Sanchez S, and Justice SS."Characterization of kinetics of innate immune response to uropathogenic Escherichia coli in a murine cystitis model" Columbus.
January 2008 Justice SS, Li B, Smith P, Horvath D, and Romesburg F."SOS response is essential for UPEC pathogenesis" .
October 2008 Anderson G; Justice S; Hultrgren S; Seed P."Exopolysaccharide capsule and sialic acid signaling contribute to key intracellular and extracellular pathways used by uropathogenic Escherichia coli during experimental cystitis" New Rochelle. : 1251
January 2009 Horvath Jr. DJ, Li B, Partida-Sanchez S, and Justice SS."Activated murine RAW 267.4 cells induce UPEC filamentation in vitro" Columbus.
January 2009 Horvath Jr. DJ, Li B, Partida-Sanchez S, and Justice SS."Activated murine RAW 267.4 cells induce UPEC filamentation in vitro" Columbus.
January 2009 Horvath Jr DJ, Lee R, Partida-Sanchez S and Justice SS."Activated murine RAW 267.4 cells induce UPEC filamentation in vitro" .
January 2009 Dabdoub SM and Justice SS."Alternate methods for visualization and analysis of flow cytometry data" Columbus.
January 2009 Dabdoub S, Justice SS and Ray WC."Exploiting biological coherence in classification and segmentation" .
October 2009 Li B, Bolton M, Horvath DJ, Partida-Sanchez S, Justice SS."Maternal UTI-mediated preterm birth: a mouse model" West Layfayette.
October 2009 Horvath, Jr. DJ, Li B, Partida-Sanchez S, Hunstad DA, Hultgren SJ, Justice SS."Filamentous morphology of uropathogenic Escherichia coli inhibits phagocytosis" West Layfayette.
October 2009 Dabdoub S, Justice SS, Ray WC."Counting Bacteria: Fluorescent image segmentation in colony member enumeration" West Layfayette.
January 2009 Szelestey BR, Justice SS, Mason KM."Morphological plasticity during heme starvation and biofilm development in nontypable Haemophilus influenzae" .
January 2009 Szelestey BR, Justice SS and Mason KM."Morphological plasticity during heme starvation and biofilm development in nontypeable Haemophilus influenzae" Columbus.
January 2009 Li B, Smith P, Horvath D, Romesburg F, and Justice SS."SOS response is essential for UPEC pathogenesis." .
January 2009 Li B, Horvath Jr. DJ, Romesberg FE, and Justice SS."SOS regulatory elements are essential for UPEC pathogenesis" Columbus.
October 2009 Storm DW, Justice SS, Horvath DJ, Li R, Koff S."Bacterial virulence of pediatric uropathogens and its relationship to urinary tract infections in children" West Layfayette.
January 2010 Storm DW, Horvath Jr. DJ, Patel A, Li B, Koff SA and Justice SS."Lower urinary tract function alter microbiological environment" St Louis.
January 2010 Storm DW, Horvath Jr. DJ, Li B, Koff SA, and Justice SS.."Pediatric uropathogens and their virulence traits: A cytokine analysis." Mason.
January 2010 Storm DW, Horvath Jr. DJ, Li B, Koff SA, and Justice SS.."Pediatric uropathogens and their virulence tTraits: A cytokine analysis." San Francisco.
January 2010 Storm DW, Horvath Jr. DJ, Li B, Koff SA, and Justice SS."Pediatric uropathogens and their virulence traits: A cytokine analysis" Columbus.
January 2010 Storm DW, Horvath Jr. DJ, Li B, Koff SA, and Justice SS."An in vitro analysis of Escherichia coli Nissle 1917: A new therapy to treat recurrent pediatric urinary tract infections" San Francisco.
January 2010 Storm DW, Horvath Jr. DJ, Li B, Koff SA and Justice SS."Pediatric uropathogens and their virulence traits: A cytokine analysis" Columbus.
January 2010 Song KJ, Post DM, Baker BD, Justice SS, Gibson BW, and Munson RS."Overexpressin of second sialytransferase gene (HD0053) is involved in the sialylation of lipooligosaccharide in Haemophilus ducreyi" San Diego.
January 2010 Song JK, Post DM, Baker BD, Justice SS, Gibson Bw, Munson Jr. RS."Overexpression of a second sialytransferase gene (HD0053) of lipopolysacchride in Haemophilus ducreyi" Columbus.
January 2010 Song JK, Post DM, Baker BD, Justice SS, Gibson BW, Monson Jr. RS."Overexpression of a second sialytransferase gene (HD0053) is involved in the sialylation of lipopolysacchride in Haemophilus ducreyi" Columbus.
January 2010 Song JK, Post DB, Baker BD, Justice SS, Gibson BW, Munson Jr. RS."Overexpression of a second sialytransferase gene (HD0053) is involved in the sialytion of lipopolysacchride in Haemophilus ducreyi" Columbus.
January 2010 Sing JK, Post DM, Baker BD, Justice SS, Gibson BW, Munwon Jr. RS."Overexpression of a second sialytransferase gene (HD0053) is involved in the sialylation of lipopolysacchride in Haemophilus ducreyi" Columbus.
January 2010 Horvath Jr. DJ, Li B, Partida-Sanchez S, and Justice SS."Defining the molecular mechanisms of inflammatory cell mediated uropathogenic Escherichia coli" St Louis.
January 2010 Horvath Jr. DJ, Li B, and Justice SS.."Novel Mechanism of sulA, induction during cystitis." Mason.
January 2010 Horvath Jr. DJ, Li B, and Justice SS."Novel mechanism of sulA induction during cystitis" Columbus.
January 2010 Horvath Jr. DJ, Li B, and Justice SS."Novel mechanism of SulA induction during cystitis" Columbus.
January 2010 Horvath Jr. DJ, Li B and Justice SS."Novel mechanism of sulA induction during cystitis" Columbus.
January 2010 Dabdoub SM, Justice SS, Ray WC."Counting bacteria: Image segmentation in colony member enumeration" Columbus.
January 2010 Dabdoub SM, Justice SS, and Ray WC.."Counting bacteria: Image segmentation in colony member enumeration." Mason.
January 2010 Dabdoub SM, Justice SS, and Ray WC."Counting bacteria: Image segmentaton into colony member enumeration" Columbus.
January 2010 Dabdoub SM, Justice SS, and Ray WC."Counting bacteria: Image segmentation in colony member enumeration" Columbus.
January 2010 Dabdoub SM, Justice SS and Ray WC."Aesthetics and understanding in molecular motion" Salt Lake City.
January 2010 Dabdoub SM and Justice SS."Let computers do the math: Automatic population discovery in flow cytometry analysis" St Louis.
January 2010 Bolton M, Horvath Jr. DJ, Li B, Partida-Sanchez S, and Justice SS.."Maternal UTI-mediated preterm birth: a mouse model." Columbus.
January 2010 Bolton M, Horvath Jr. DJ, Li B, Partida-Sanchez S, and Justice SS."Maternal UTI-mediated preterm birth:A mouse model" Columbus.
January 2010 Bolton M, Horvath Jr. DJ, Li B, Partida-Sanchez S, and Justice SS."Maternal UTI-mediated Preterm Birth: A Mouse Model" Vancouver.
January 2010 Bolton M, Horvath Jr. DJ, Li B, Koff SA and Justice SS."Pediatric uropathogens and their virulence traits: A cytokine analysis" Columbus.
January 2011 Spencer JD, Schwaderer A, DiRosario J, McHugh K, Baker P, Justice SS, Hains D."Ribonuclease 7: A potent antimicrobial peptide in the human kidney and urinary tract" Columbus.
January 2011 Spencer J, Schwaderer A, DiRosario J, McHugh K, Baker P, Justice SS, Hains D."Ribonuclease 7: a potent antimicrobial peptide in the human kidney and urinary tract" Denver.
January 2011 Dabdoub SM. Ray WC and Justice SS."FIND: A new software tool and development platform for enhanced multicolor flow analysis" Columbus.
January 2011 Dabdoub SM, Ray WC and Justice SS."FIND: A new software took and development platform for enhanced multicolor flow analysis" Athens.
January 2011 Dabdoub SM, Ray WC and Justice SS."Quantitative analysis and comparison of intracellular biofilms in E. coli induced cystitis" Columbus.
January 2011 Dabdoub SM, Ray WC and Justice SS."FIND:A new software tool and development platform for enhanced multicolor flow analysis" Columbus.
January 2011 Szelestey B, Dabdoub SM, Justice SS, and Mason K."Heme availability influences biofilm development and architecture by nontypeable Haemophilus influenzae" Columbus.
January 2011 Li B, Downey JS, Goodman SD and Justice SS."Double stranded DNA binding protein IHF affects UPEC pathogenesis" Columbus.
January 2011 Li B, Downey JS, Goodman SD and Justice SS."Double stranded DNA binding protein IHF affects UPEC pathogenesis" Athens.
January 2011 Li B, Downey JS, Goodman SD and Justice SS."Double stranded DNA binding protein IHF affects UPEC pathogenesis" Columbus.
January 2011 Li B, Downey J, Dabdoub S, Brockson ME, Probst GD, Goodmans SD and Justice SS."Homodimers of IHF retain function during the pathogenesis of uropathogenic Escherichia coli" Ann Arbor.
January 2011 Kozlovich C, Patel A, Storm DW, Horvath DJ, Li B, Koff SA and Justice SS."Lower urinary tract function alters microbiological invironment" Ann Arbor.
January 2011 Becknell B, Meadows A, Li B, Hains DS, Schwaderer AL, Justice SS, and McHugh KM."Regulation of murine beta-defensin-1 (mBD-1) antimicrobial peptide in response to gram-negative bladder infection." Boston.
January 2011 Patel A, Storm DW, Horvath Jr. DJ, Li B, Koff SA, and Justice SS."Lower urinary tract infections alter microbiological environment" Columbus.
January 2011 Patel A, Storm DW, Horvath Jr. DJ, Li B, Koff SA and Justice SS."Lower urinary tract functions alter microbiological environment" Columbus.
January 2011 Patel A, Storm D, Horvath Jr. DJ, Li B, Koff SA and Justice SS."Lower urinary tract function alters microbiological environment" Athens.
January 2011 Horvath Jr. DJ, Cortado H, Justice SS, and Partida-Sanchez S."Resident macrophages are required for control of urinary tract infection in mice" Columbus.
January 2011 Horvath Jr. DJ, Cortado H, Justice SS and Partida-Sanchez S."Resident macrophages are required for control of urinary tract infections in mice" Athens.
January 2011 Horvath DJ, Cortado H, Justice SS and Partida-Sanchez S."Resident macrophages are required for control of urinary tract infection in mice" Columbus.
January 2011 Dabdoub SM, Ray W and Justice SS."Quantitative analysis and comparison of intracellular biofilms in E. coli induced cystitis" Ann Arbor.
April 2012 Szelestet BR, Raffel FKm, Justice SS, and Mason KM."Transient heme-iron restriction primes altered biofilm architecture and enhanced fitness of nontypeable Haemophilus influenzae in vivo" Mason.
April 2012 Kozlovich CE, Singh C, Baxter C, Li B, Patel A and Justice SS."Characteristics of lower urinary tract infection pathogens in a clinical trial of LoFric catheter in a clean intermittent catheterization patients" Mason.
October 2012 Lucas EJ, Li B, and Justice SS."Targeted replacement of uropathogens with Probiotic Nissle 1917" Columbus.
September 2012 Kozlovich CE, Li B and Justice SS."Reactive species produced by murine macrophages induce filamentation of uropathogenic Escherichia coli" Milwaukee.
September 2012 Heimlich DR, Szelestey BR, Raffel FK, Justice SS and Mason KM."Transient heme-iron restriction perpetuates enhanced biofilm architecture thtat influences persistence of Nontypeable Haemophilus influenzae and disease severity" Milwaukee.
October 2012 Kozlovich CD, Singh C, Bazter C, Li B, and Justice SS."Identifying differences between pneumococcal strains that may contribute to development of hemolytic uremic syndrone" Columbus.
October 2012 Becknell B, Carpenter A, Schwaderer A, Hains DS, Justice SS, and McHugh KM."The best offense is a good defense: Exoression and function of beta defensins in the infected kidney and urinary tract" Columbus.
May 2013 Lucas EJ, Li B, and Justice SS."Targeted replacement of uropathogens with Probiotic Nissle 1917" Columbus.
May 2013 Lucas EJ, Li B, and Justice SS."Targeted replacement of uropathogens with Probiotic Nissle 1917" Washington DC.
Lucas EJ, Li B and Justice SS."Targeted replacement of uropathogens with Probiotic Nissle 1917" .
Lucas EJ, Li B and Justice SS."Targeted replacement of uropathogens with Probiotic Nissle 1917" .

Inventions and Patents

Santiago Partida-Sanchez, Ph.D. and Sheryl Justice, Ph.D.. "Risk predictors for adverse perinatal outcomes." Filed September 2011.

Santiago Partida-Sanchez, Ph.D. and Sheryl Justice, Ph.D.. "Risk predictors for adverse perinatal outcomes." Filed September 2012.

Sheryl Justice, Ph.D. and Shareef Dabdoub. "Automated analysis of multi-color flow cytometry data by principle component analysis and clustering." Filed August 2009.

 

Presentations

"Consequences of Host-Pathogen Interactions on UPEC Persistence and Disease Sequelae." Presented at Department of Surgery, University of Cincinnati, . (September 2013)

"Consequences of Host-Pathogen INteractions on UPEC Persistence and Disease Sequelae." Presented at Department of Pathology, University of Utah, . (October 2013)

"Consequences of Host-Pathogen Interactions on UPEC Persistence and Disease Support." Presented at Department of Microbiology and Immunity, Tulane University, . (November 2013)

"Consequences of Host-Pathogen Interactions on UPEC Persistence and Disease Sequelae." Presented at Department of Microbiology and Immunity, Wake Forrest School of Medicine, . (December 2013)

"Consequences of Host-Pathogen Interactions on UPEC Persistence and Disease Sequelae." Presented at Deparment of Microbioloigy, University of Alabama at Birmingham, . (March 2014)

"Consequences of Host-Pathogen Interactions on UPEC Persistence and Disease Sequelae." Presented at Department of Microbiology/Immunology, University of Buffalo, . (March 2014)