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Sheryl Justice, PhD


Staff photo

700 Childrens Dr
Ctr for Microbial Pathogenesis
Columbus, OH 43205

Phone: (614) 722-4196

Email: justice.133@osu.edu

 

Current OSU Appointment

Associate Professor, Pediatrics

 

Chapters in Books

Justice SS, Dodson KW, Chapman MR, Barnhart MM and SJ Hultgren. "Assembly of Adhesive Organelles on Gram Negative Bacteria." In Protein Secretion Pathways in Bacteria. First ed. Edited by Bauke Oudega. 207-232. New York, NY, US|USA: Kluwer Academic Publishers, January 2003.

Olson P, Justice SS and Hunstad DA. "Escherichia coli in urinary tract infections." In Medical Molecular Microbiology. -. Waltham: Elsevier Academic Press, January 2014.

 

Degrees

1986 A.A.S., University of Missouri

1994 B.S.C.E., University of Missouri

2001 B.F.A., University of Connecticut

 

Journal Articles

Stader J and Justice SS.. "Export and trimerization pathways of maltoporin overlap in the inner membrane of Escherichia coli." Journal of Molecular Biology. no. 238. (January 1994.): 555-562.

Stader J and Justice SS. "Export and trimerization pathways of maltoporin overlap in the inner membrane of Escherchia coli." Journal of Molecular Biology. Vol. 238, no. 4. (May 1994.): 555-562.

Rothfield L and Justice SS. "Bacterial cell division: The cycle of the ring." Cell. Vol. 88, no. 5. (March 1997.): 581-584.

Rothfield L and Justice SS. "Bacterial Cell Division: The cycle of the Ring." Cell. no. 88. (January 1997.): 581-858.

Rothfield L, Justice SS and Garcia-Lara J. "Bacterial cell division." Annual Review of Genetics. Vol. 33, (January 1999.): 423-448.

Rothfield L, Justice SS and GarcĂ­a-Lara J. "Bacterial cell division." Annual Review in Genetics. no. 33. (January 1999.): 423-448.

Justice SS, Garcia-Lara J and Rothfield LI. "Cell division inhibitors SulA and MinC/MinD block septum formation at different steps in the assembly of the Escherichia coli division machinery." Molecular Microbiology. Vol. 2, no. 37. (January 2000.): 410-423.

Justice SS, Garcia-Lara J and Rothfield LI. "Cell division inhibitors SulA and MinC/MinD block septum formation at different steps in the assembly of the Escherichia coli division machinery." Molecular Microbiology. Vol. 37, no. 2. (July 2000.): 410-423.

Schilling JD, Martin SM, Hunstad DA, Patel KP, Mulvey MA, Justice SS, Lorenz RG and Hultgren SJ. "CD14-and toll-like receptor-devendent activation of bladder epithelial cells by lipopolysaccharide and type 1 piliated Escherichia coli." Infection and Immunity. Vol. 71, no. 3. (March 2003.): 1470-1480.

Schilling JD, Martin SM, Hunstad DA, Patel KP, Mulvey MA, Justice SS, Lorenz RG and Hultgren SJ. "CD14- and toll-like receptor- dependent activation of bladder epithelial cells by lipopolysaccharide and type 1-piliated E. coli." Infection and Immunity. Vol. 3, no. 71. (January 2003.): 1470-1480.

Justice SS CS, Theriot JA, Fletcher DA, Anderson GG, Footer MJ and Hultgren SJ. "From the cover: Differentiation and developmental pathways of uropathogenic E. coli in urinary tract pathogenesis." Proceedings of the National Academy of Sciences, USA. Vol. 5, no. 101. (January 2004.): 1333-1338.

Justice SS, Hung C, Theriot JA, Fletcher DA, Anderson GG, Footer MJ and Hultgren SJ. "Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis." Proceedings of the National Academy of Sciences of the United States of America. Vol. 101, no. 5. (February 2004.): 1333-1338.

Justice SS, Hunstad DA, Harper JR, Duguay AR, Pinkner JS, Bann J, Frieden C, Silhavy TJ and Hultgren SJ. "Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability, but SurA is required for pilus biogenesis in Escherichia coli." Journal of Bacteriology. Vol. 187, no. 22. (November 2005.): 7680-7686.

Justice SS, Hunstad DA, Reiss Harper J, Duguay A, Pinkner JS, Bann J, Frieden C, Silhavy TJ and Hultgren SJ. "Periplasmic peptidyl prolyl cis-trans isomerases are not essential for viability but are required for pilus biogenesis in Escherichia coli." Journal of Bacteriology. Vol. 22, no. 187. (January 2005.): 7680-7686.

Hunstad DA, Justice SS, Hung CS, Lauer SR and Hultgren SJ. "Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli." Infection and Immunity. Vol. 7, no. 73. (January 2005.): 3999-4006.

Hunstad DA, Justice SS, Hung CS, Lauer SR and Hultgren SJ. "Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli." Infection and Immunity. Vol. 73, no. 7. (July 2005.): 3999-4006.

Justice SS, Hunstad DA, Seed PC and Hultgren SJ. "Filamentation by Escherichia coli subverts innate defenses during urinary tract infection." Proceedings of the National Academy of Sciences of the United States of America. Vol. 103, no. 52. (December 2006.): 19884-19889.

Justice SS, Lauer SR, Hultgren SJ and Hunstad DA. "Maturation of intracellular Escherichia coli communities requires SurA." Infection and Immunity. Vol. 74, no. 8. (August 2006.): 4793-4800.

Justice SS, Lauer SR, Hultgren SJ and Hunstad DA. "Maturation of intracellular Escherichia coli communities requires SurA." Infection and Immunity. Vol. 9, no. 74. (January 2006.): 4793-4800.

Justice SS, Hunstad DA, Seed PC and Hultgren SJ. "Filamentation by E. coli subverts innate defenses during urinary tract infections." Proceedings of the National Academy of Sciences, USA. Vol. 52, no. 103. (January 2007.): 19884-19889.

Justice SS, Hunstad DA, Cegelski L and Hultgren SJ.. "Morphological plasticity as bacterial survival strategy." Nature Reviews in Microbiology. Vol. 6, (February 2008.): 162-168.

Justice SS, Hunstad DA, Cegelski L and Hultgren SJ. "Morphological plasticity as a bacterial survival strategy." Nature Reviews Microbiology. Vol. 6, no. 2. (February 2008.): 162-168.

Anderson, G; Justice, S; Hultgren, S, and Seed PC. "Exopolysaccharide capsule and sialic 10. Acid signaling contribute to key intracellular and extracellular pathways used by uropathogenic Escherichia coli during experimental cystitis." Journal of Womens Health. Vol. 8, no. 17. (October 2008.): 1251-1251.

Anderson G, Justice SS, Hultgren S and Seed P. "Exopolysaccharide capsule and sialic acid signaling contribute to key intracellular and extracellular pathways used by uropathogenic Escherichia coli during experimental cystitis." Journal of Womens Health. Vol. 17, no. 8. (October 2008.): 1251-1251.

Justice SS and Hunstad DA. "Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli." Annual Review of Microbiology. Vol. 64, (January 2010.): 203-221.

Li B, Smith P, Horvath DJ, Romesberg FE and Justice SS. "SOS regulatory elements are essential for UPEC pathogenesis." Microbes and Infection. Vol. 12, no. 8-9. (August 2010.): 662-668.

Justice S and Hunstad D. "Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli." Annual Review Microbiology. Vol. 13, no. 64. (January 2010.): 203-221.

Anderson GG, Goller CC, Justice SS, Hultgren SJ and Seed PC. "Polysaccharide capsule and sialic acid-mediated regulation promote biofilm-like intracellular bacterial communities during cystitis." Infection and Immunity. Vol. 78, no. 3. (March 2010.): 963-975.

Anderson GG, Goller CC, Justice S, Hultgren SJ, and Seed PC. "Polysaccharide capsule and sialic acid-mediated regulation promote intracellular bacterial communities during cystitis." Infection and Immunity. Vol. 3, no. 78. (March 2010.): 963-975.

Li B, Smith P, Horvath Jr. DJ, Romesberg F, Justice SS. "SOS regulatory elements are essential for UPEC pathogenesis." Microbes and Infection. Vol. 12, no. 8-9. (January 2010.): 662-668.

Storm DW, Patel AS, Koff SA and Justice SS. "Novel management of urinary tract infections." Current Opinion in Urology. Vol. 21, no. 4. (July 2011.): 328-333.

Dabdoub SM, Ray WC and Justice SS. "FIND: A new software tool and development platform for enhanced multicolor flow analysis." BMC Bioinformatics. Vol. 12, (May 2011.): 145-.

Storm,Douglas,W; Koff,Stephen,A; Horvath,Dennis,J; Li,Birong; Justice,Sheryl,S. "In Vitro Analysis of the Bactericidal Activity of Escherichia Coli Nissle 1917 Against Pediatric Uropathogens." JOURNAL OF UROLOGY. Vol. 186, no. 4. (October 2011.): 1678-1683.

Storm DW, Patel AS, Koff SA and Justice SS.. "Novel management of urinary tract infections.." Current Opinions in Urology. Vol. 4, no. 21. (July 2011.): 328-333.

Horvath DJ, Li B, Casper T, Partida-Sanchez S, Hunstad DA, Hultgren SJ and Justice SS. "Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli." Microbes and Infection. Vol. 13, no. 5. (May 2011.): 426-437.

Goodman SD, Obergfell KP, Jurcisek JA, Novotny LA, Downey JS, Ayala EA, Tjokro N, Li B, Justice SS and Bakaletz LO. "Biofilms can be dispersed by focusing the immune system on a common family of bacterial nucleoid associated proteins." Mucosal Immunity. Vol. 6, no. 4. (November 2011.): 625-637.

Storm DW, Koff SA, Horvath Jr. DJ, Li B and Justice SS. "An in vitro analysis of the bactericidal activity of Escherichia coli Nissle 1917 against pediatric uropathogens." Journal of Urology. Vol. 186, no. 4. (October 2011.): 1678-1683.

Horvath Jr. DJ, Li B, Partida-Sanchez S, Hunstad DA, Hultgren SJ and Justice SS. "Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli.." Microbes and Infection. Vol. 5, no. 13. (May 2011.): 426-437.

Dabdoub SM, Ray WC and Justice SS.. "FIND: A new software tool and development platform for enhanced multicolor flow analysis.." BMC Bioinformatics. Vol. 12, no. 10. (May 2011.): 145-.

Dabdoub SM, Justice SS and Ray WC. "A dynamically masked gaussian can efficiently approximate a distance calculation for image segmentation." Software Tools and Algorithims for Biological Systems. Vol. 696, (January 2011.): 425-432.

Dabdoub S, Justice SS, Ray WC. "A dynamically masked gaussian can efficiently approximate a distance calculation for image segmentation." Advances in Experimental Medicine and Biology. no. 696. (January 2011.): 425-432.

Spencer JD, Schwaderer A, DiRosario J, McHugh KM, McGillivary G, Justice SS, Carpenter A, Baker P, Harder J, and Hains DS.. "Ribonuclease 7: a potent antimicrobial peptide within the human urinary tract.." Kidney International. Vol. 80, no. 2. (July 2011.): 174-180.

Goodman,S,D; Obergfell,K,P; Jurcisek,J,A; Novotny,L,A; Downey,J,S; AYALA,E,A; Tjokro,N; Li,B; Justice,S,S; Bakaletz,L,O. "Biofilms can be dispersed by focusing the immune system on a common family of bacterial nucleoid-associated proteins." MUCOSAL IMMUNOLOGY. Vol. 4, no. 6. (November 2011.): 625-637.

Spencer JD, Schwaderer AL, Dirosario JD, McHugh KM, McGillivary G, Justice SS, Carpenter AR, Baker PB, Harder J and Hains DS. "Ribonuclease 7 is a potent antimicrobial peptide within the human urinary tract." Kidney International. Vol. 80, no. 2. (July 2011.): 175-181.

Justice SS, Li B, Downey JS, Brockson ME, Ray WC and Goodman SD. "Aberrant community architecture and attenuated persistence of uropathogenic Escherichia coli in the absence of individual IHF subunits." PLoS One. Vol. 7, no. 10. (October 2012.): e48349-.

Storm DW, Patel AS, Horvath Jr. DJ, Li B, Koff SA and Justice SS. "Relationship among bacterial virulence, bladder function and patterns of urinary tract infection in children." Journal of Urology. (January 2012.): -.

Horvath Jr. DJ, Dabdoub SM, Li B, VanderBrink BA and Justice SS. "New paradigms of urinary tract infections: Implications for patient management." Indian Journal of Urology. Vol. 28, no. 2. (April 2012.): 154-158.

Justice SS and Hunstad DA. "UPEC hemolysin: More than just for making holes." Cell Host and Microbe. Vol. 11, no. 1. (January 2012.): 4-5.

Storm DW, Patel AS, Horvath DJ, Li B, Koff SA and Justice SS. "Relationship among bacterial virulence, bladder dysfunction, vesicoureteral reflux and patterns of urinary tract infection in children." Journal of Urology. Vol. 188, no. 1. (July 2012.): 236-241.

Storm,Douglas,W; Patel,Ashay,S; Horvath,Dennis,J; Li,Birong; Koff,Stephen,A; Justice,Sheryl,S. "Relationship Among Bacterial Virulence, Bladder Dysfunction, Vesicoureteral Reflux and Patterns of Urinary Tract Infection in Children." JOURNAL OF UROLOGY. Vol. 188, no. 1. (July 2012.): 236-241.

Storm,Douglas,W; Patel,Ashay,S; Horvath,Dennis,J; Li,Birong; Koff,Stephen,A; Justice,Sheryl,S. "Relationship Among Bacterial Virulence, Bladder Dysfunction, Vesicoureteral Reflux and Patterns of Urinary Tract Infection in Children." JOURNAL OF UROLOGY. Vol. 188, no. 1. (July 2012.): 236-241.

Justice SS and Hunstad DA. "UPEC Hemolysin: More than Just for Making Holes." Cell Host & Microbe. Vol. 11, no. 1. (January 2012.): 4-5.

Storm,Douglas,W; Patel,Ashay,S; Horvath,Dennis,J; Li,Birong; Koff,Stephen,A; Justice,Sheryl,S. "Relationship Among Bacterial Virulence, Bladder Dysfunction, Vesicoureteral Reflux and Patterns of Urinary Tract Infection in Children." JOURNAL OF UROLOGY. Vol. 188, no. 1. (July 2012.): 236-241.

Bolton M, Horvath Jr. DJ, Li B, Cortado N, Newsom D, White P, Partida-Sanchez S and Justice SS. "Intrauterine growth restriction is a direct consequence of localized maternal uropathogenic Escherichia coli cystitis." PLoS One. Vol. 7, no. 3. (January 2012.): e33897-.

Vogel AR, Szelestey BR, Raffel FK, Sharpe SW, Gearinger RL, Justice SS and Mason KM. "SapF-mediated heme-iron utilization enhances persistence and coordinates biofilm architecture of Haemophilus." Frontiers in Cellular and Infection Microbiology. Vol. 2, (January 2012.): 42-.

Szelestey, Blake, R., Heimlich, Derek, R., Raffel, Forrest, K., Justice, Sheryl, S., Mason, K.M.. "Haemophilus responses to nutritional immunity: epigenetic effects on biofilm architecture, persistence and disease severity." PLoS Pathogens. Vol. 7, no. 10. (October 2012.): e48349-.

Partida-Sanchez S, Horvath D, Cortado H, Li B, Flano E and Justice SS. "Monocyte-derived inflammatory dendritic cells expressing CX3CR1 control urinary tract infection in mice." Journal of Immunology. Vol. 188, no. 120. (May 2012.): 25-.

Horvath DJ, Dabdoub SM, Li B, VanderBrink BA and Justice SS. "New paradigms of urinary tract infections: Implications for patient management." Indian Journal of Urology. Vol. 188, no. 1. (April 2012.): 236-241.

Becknell B, Spencer JD, Carpenter AR, Chen X, Ploeger S, Kline J, Ellsworth P, Li B, Proksch E, Schwaderer AL, Hains DS, Justice SS and McHugh KM. "Expression and antimicrobial function of Beta-defensin 1 in the lower urinary tract." Plos One. Vol. 8, no. 10. (October 2013.): e7714-.

Spencer JD, Schwaderer AL, Eichler T, Wang H, Kline J, Justice SS, Cohen DM, Hains DS. "An endogenous Ribonuclease inhibitor regulates the antimicrobial activity of Ribonuclease 7 in the human urinary tract." Kidney International. Vol. 0, no. Epub ahead of print. (October 2013.): 0-.

Spencer JD, Schwaderer AL, Eichler T, Wang H, Kline J, Justice SS, Cohen DM, Hains DS. "An endogenous Ribonuclease inhibitor regulates the antimicrobial activity of Ribonuclease 7 in the human urinary tract." Kidney International. Vol. Epub anead of print, (October 2013.): 0-.

Partida-Sanchez S, Cortado H, Horvath D, Li R, Flano E and Justice S[S. "Nonclassical monocyte-derived macrophages are essential for preventing pyelonephritis upon urinary tract infection in mice." Journal of Immunology. Vol. 190, no. 130. (May 2013.): 14-.

Mohamed A, Li B, Jayanthi V and Justice SS. "Immunomodulatory capacity accurately predicts disease severity caused by different strains of uropathogenic Escherichia coli." Journal of Urology. Vol. 189, no. 4. (April 2013.): E471-E472.

Szelestey BR, Heimlich DR, Raffel FK, Justice SS and Mason KM. "Haemophilus responses to nutritional immunity: epigenetic and morphological contribution to biofilm architecture, invasion, persistence and disease severity." PLoS Pathogens. Vol. 9, no. 10. (January 2013.): e1003709-.

Szelestey, B.R., Heimlich, D.R., Raffel, F.K., Justice, S.S., and Mason, K.M.. "Haemophilus responses to nutritional immunity: Epigenetic and morphological contribution to biofolm archicture, persistence and disease." PLoS Pathogens. Vol. 9, no. 10. (October 2013.): e1003709-.

Spencer JD, Schwaderer AL, Eichler T, Wang H, Kline J, Justice SS, Cohen DM and Hains DS. "An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract." Kidney International. Vol. 85, no. 5. (October 2013.): 1179-1191.

Justice SS, Harrison A, Becknell B, Mason KM. "Bacterial differentiation, development and disease: mechanisms for survival." FEMS Microbiol Lett. Vol. 360, no. 14. (November 2014.): 1-8.

Justice SS, Harrison A, Becknell B and Mason KM. "Bacterial differentiation, development and disease: mechanisms for survival." FEMS Microbiological Letters. Vol. 360, no. 1. (November 2014.): 1-8.

Devarag A, Justice SS, Bakaletz LO, Goodman SD. "DNABII proteins play a central role in UPEC biofilm structure." Mol Microbiol. Vol. 96, no. 6. (June 2015.): 1119-1135.

Scott VC, Haake DA, Churchill BM, Justice SS, Kim JH. "Intracullular bacterial communitites: A potential etiology for chronic lower urinary tract symptoms." Urology. Vol. 86, no. 3. (September 2015.): 425-431.

Harrison A, Dubois LG, St John-Williams L, Moseley MA, Hardison RL, Heimlich DR, Stoddard A, Kerschner JE, Justice SS, Thompson JW, Mason KM. "Comprehensive proteomic and metablolmic signatures of nontypeable Haemophilus influenzae induced acute otitis media reveal bacterial aerobic respiration in an immunosupporessed environment." Mol Cell Proteomics. Vol. pii:mcp.M115.0522498 [Epub ahead of print], (December 2015.): 1-.

Horvath Jr DJ, Patel AS, Mohamed A, Storm DW, Singh C, Li B, Zhang J, Koff SA, Jayanthia VR, Mason KM, JusticeSS. "Association of O-antigen serotype with the magnitude of initial systemic cytokine responses and persistence in the urinary tract." J Bact. Vol. pii:JB.00664-15 [Epub ahead of print], (January 2016.): 1-.

 

Professional Activities

0 Midwest Society for Pediatric Nephrology. Columbus, OH.