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Prosper N. Boyaka, PhD


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1900 Coffey Rd
Columbus, OH 43210

Phone: (614) 247-4671

Email: boyaka.1@osu.edu

 

Current OSU Appointments

Professor, Veterinary Biosciences

Professor, Pulmonary, Crit Care, & Sleep

 

Academic Advising

2009 - present Caroline Desclée, AgroParisTech.
2009 - present Morgane Thierry-Mieg, AgroParisTech.
1996 - 1998 Salieu Abraham, University of Alabama. Graduated 1998. An automated immunofluorescence microscopy system for the characterization of mucosally derived single cell immune responses
2001 - 2005 Romy Fisher, University of Alabama. Graduated 2005. Mouse models of peanut allergyContribution of oral and nasal sensitization to allergic reactions topeanut and cross-reactivity with food and environmental antigens
2002 - 2005 Angela Tafaro, University of Alabama.
2004 - 2005 Cecilia Vuillard, University of Alabama. Graduated 2005.
2005 - 2006 Elodie Muraz, University of Alabama. Graduated 2006.
2005 - 2006 Edith Crenn, University of Alabama. Graduated 2006.
2003 - 2007 Alexandra Duverger, The Ohio State University. Graduated 2007. Regulation of mucosal immune responses by anthrax edema toxin derivatives
2006 - 2007 Chloe Manificat, Institut National Agronomique Paris-Grignon. Graduated 2007.
2006 - 2007 Juliette Trepreau, Institut National Agronomique Paris-Grignon. Graduated 2007.
2007 - 2008 Sanjay Singh, The Ohio State University.
2007 - 2008 Jeanne-Marie Carre, AgroParisTech. Graduated 2008.
2008 - 2009 Igor Stzepourginski, AgroParisTech. Graduated 2009.
2008 - 2009 Xavier Duportet, AgroParisTech. Graduated 2009.
 

Chapters in Books

Fujihashi, K., S. Yamamoto, M. Marinaro, M. Kweon, J.L. VanCott, M. Yamamoto, K. Imaoka, P.N. Boyaka, F.W. van Ginkel, H. Kurazono, R.J. Jackson, H. Kiyono and J.R. McGhee.. "Regulation of mucosal immune responses by helper T cells and cytokines." In Inflammatory Bowel Diseases and Chronic Recurrent Abdominal Pain. Edited by Hadziselimovic F. and B. Herzog,. 62-82. Dordrecht, DE|DEU: Kluwer Academic Publishers, January 1996.

Kiyono, H., K. Fujihashi, M. Yamamoto, T. Hiroi, M. Coste, S. Kawabata, P.N. Boyaka and J.R. McGhee. "Intraepithelial gd T cells and epithelial cell interactions in the mucosal immune system.." In Essential of Mucosal Immunology. Edited by M.F. Kagnoff and H. Kiyono. 195-205. San Diego, CA, US|USA: Academic Press, January 1996.

Boyaka, P.N., J.W. Lillard, Jr., S. Yamamoto and J.R. McGhee.. "Mutant enterotoxins and mucosally administered cytokines for safe targeting of Th1- and Th2-type responses by mucosal adjuvants.." In Induction and Modulation of Gastrointestinal Inflammation. 81-93. Dordrecht, DE|DEU: Kluwer Academic Publishers, January 1999.

Boyaka, P.N., M. Marinaro, K. Fujihashi, and J.R. McGhe. "Host defense at mucosal surfaces.." In Clinical Immunology. 2nd ed. Edited by R.R. Rich, T.A. Fleisher, W.T. Shearer, B.L. Kotzin, H.W. Schroeder Jr.. 20.1-20.18. London: Mosby International Limited, January 2001.

Boyaka, P.N., and J.R. McGhee.. "Immune defense at mucosal surfaces.." In Immunotherapy for Infectious Diseases.. Edited by J.M. Jacobson. 39-60. Amsterdam, NL|NLD: Humana Press, January 2002.

Boyaka, P.N., J.R. McGhee, C. Czerkinsky, and M. Mestecky.. "Mucosal vaccines: an overview." In Mucosal Immunology. 3rd ed. Edited by Mestecky, J., Bienenstock, J., Lamm, M., Mayer, L., Mcghee, J.R., and Strober, W. 855-874. Amsterdam, NL|NLD: Academic Press, January 2005.

Fujihashi, K., P.N. Boyaka, and J.R McGhee.. ". Mucosal immune responses." In Microbiology and Microbial Infections. Edited by S.H.E. Kaufmann. 519-555. London: Edward Arnold Limited, January 2005.

Boyaka PN., A. Duverger, E. Cormet-Boyaka, and J.-N. Tournier.. "Mucosal immunity against anthrax." In Immunity against mucosal pathogens. Edited by M Vajdy. 367-381. Amsterdam: Springer Science, January 2008.

Fujihashi, K., P.N. Boyaka, and J.R. McGhe. "Mucosal immune responses." In Clinical Immunology. 3rd ed. Edited by R.R. Rich, T.A. Fleisher, W.T. Shearer, H.W. Schroeder Jr., A.J. Frew, CM. Weyand.. 287-303.. London: Mosby International Limited, January 2008.

 

Degrees

1989 M.S., University Paris 7, Dennis Diderot

1994 Ph.D., University Paris 7, Dennis Diderot

 

Editorial Activities

2000 - 2002 Infection and Immunity
2001 - 2005 The Journal of Immunology
2002 - present Vaccine
2004 - present Microbes and Infection
2005 - present The Journal of Immunology
2005 - present Proceeding of the national academy of sciences (PNAS)
2005 - present Current Immunology Reviews
2006 - present Immunity
2008 - present Mucosal Immunology
 

Journal Articles

BOYAKA, P; COSTE, M; ROCHET, V; TOME D. "Effect Of Neuraminidase Treatment Of The Proliferative Response Of Rat Intestinal Intraepithelial Lymphocytes." Gastroenterology. Vol. 100, no. 5 PART 2. (January 1991.): A564-.

Coste, M.; Boyaka, P. N.; Dubarry, M.; Tome, D.. "Differential susceptibility of Iels and spleen cells to bacterial neuraminidase in rats." Gastroenterology. Vol. 104, no. 4 SUPPL.. (January 1993.): A686-.

Coste, M.; Boyaka, P. N.; Dubarry, M.; Tome, D.. "Desialation of intraepithelial lymphocytes: Relation with cell proliferation and gamma-interferon production." FASEB Journal. Vol. 7, no. 3-4. (January 1993.): A369-.

Portier, A.; Boyaka, N. P.; Bougoudogo, F.; Dubarry, M.; Huneau, J. F.; Tome, D.; Dodin, A.; Coste, M.. "Fermented milks and increased antibody responses against cholera in mice." International Journal of Immunotherapy. Vol. 9, no. 4. (January 1993.): 217-224.

Boyaka, P. N.; Dubarry, M.; Rautureau, M.; Coste, M.; Tome, D.. "Differential susceptibility of Caco-2 cell enzymatic activities to Clostridium perfringens neuraminidase." FASEB Journal. Vol. 8, no. 4-5. (January 1994.): A17-.

Boyaka, P, N; Coste, M; Tome, D. "Desialylation of rat intraepithelial lymphocytes: effects on proliferation and dipeptidyl peptidase IV activity.." Advances in experimental medicine and biology. Vol. 371A, (January 1995.): 133-6.

Marinaro, M; Staats, H, F; Hiroi, T; Jackson, R, J; Coste, M; Boyaka, P, N; Okahashi, N; Yamamoto, M; Kiyono, H; Bluethmann, H; Fujihashi, K; McGhee, J R. "Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4.." Journal of immunology (Baltimore, Md. : 1950). Vol. 155, no. 10. (January 1995.): 4621-9.

Yamamoto, M.; McGhee, J. R.; Kurazono, H.; Shimpuku, Y.; Boyaka, P. N.; Marinaro, M.; Jackson, R. J.; Kiyono, H.. "Effect of Lt on mucosal immune responses in Il-4 knockout mice." FASEB Journal. Vol. 10, no. 6. (January 1996.): A1190-.

Marinaro, M; Boyaka, P, N; Jackson, R, J; Finkelman, F, D; Kiyono, H; McGhee, J R. "Interleukin-12 alters helper T-cell subsets and antibody profiles induced by the mucosal adjuvant cholera toxin.." Annals of the New York Academy of Sciences. Vol. 795, (January 1996.): 361-5.

Marinaro, M.; Boyaka, P. N.; Jackson, R. J.; Finkelman, F. D.; Gately, M. K.; Kiyono, H.; McGhee, J. R.. "Mucosal administration of rmil-12 to mice modulates Th2-type responses induced by an oral vaccine." FASEB Journal. Vol. 10, no. 6. (January 1996.): A1036-.

Boyaka, P. N.; Fujihashi, K.; McGhee, J. R.; Kawabata, S.; Kiyono, H.. "Tip and crypt intestinal epithelial cells express different levels of Cd80 and Cd86 molecules." FASEB Journal. Vol. 10, no. 6. (January 1996.): A1363-.

Boyaka, P. N.; Fujihashi, K.; McGhee, J. R.; Kawabata, S.; Kiyono, H.. "Tip and crypt intestinal epithelial cells express different levels of Cd80 and Cd86 molecules." FASEB Journal. Vol. 6, (January 1996.): A1363-.

Pascual, David W.; Coste, Michel; Boyaka, Prosper N.; Kiyono, Hiroshi; McGhee, Jerry R.. "Spontaneously hypertensive rat: Cholera toxin converts suppression to immunity through a Th2 cell-il-4 pathway." American Journal of Physiology. Vol. 273, no. 4 PART 2. (January 1997.): R1509-R1518.

Pascual, D, W; Coste, M; Boyaka, P, N; Kiyono, H; McGhee, J R. "Spontaneously hypertensive rat: cholera toxin converts suppression to immunity through a Th2 cell-IL-4 pathway.." The American journal of physiology. Vol. 273, no. 4 Pt 2. (January 1997.): R1509-18.

Kawabata, Shigetada; Boyaka, Prosper N.; Coste, Michel; Fujihashi, Kohtaro; Hamada, Shigeyuki; McGhee, Jerry R.; Kiyono, Hiroshi. "A novel alkaline phosphatase-based isolation method allows characterization of intraepithelial lymphocytes from villi tip and crypt regions of murine small intestine." Biochemical and Biophysical Research Communications. Vol. 241, no. 3. (January 1997.): 797-802.

Kawabata, S; Boyaka, P, N; Coste, M; Fujihashi, K; Hamada, S; McGhee, J, R; Kiyono, H. "A novel alkaline phosphatase-based isolation method allows characterization of intraepithelial lymphocytes from villi tip and crypt regions of murine small intestine.." Biochemical and biophysical research communications. Vol. 241, no. 3. (January 1997.): 797-802.

Marinaro, Mariarosaria; Boyaka, Prosper N.; Finkelman, Fred D.; Kiyono, Hiroshi; Jackson, Raymond J.; Jirillo, Emilio; McGhee, Jerry R.. "Oral but not parenteral interleukin (il)-12 redirects T helper 2 (th2)-type responses to an oral vaccine without altering mucosal Iga responses." Journal of Experimental Medicine. Vol. 185, no. 3. (January 1997.): 415-427.

Marinaro, M; Boyaka, P, N; Finkelman, F, D; Kiyono, H; Jackson, R, J; Jirillo, E; McGhee, J R. "Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)-type responses to an oral vaccine without altering mucosal IgA responses.." The Journal of experimental medicine. Vol. 185, no. 3. (January 1997.): 415-27.

Marinaro, M.; Boyaka, P. N.; Jackson, R. J.; Finkelman, F. D.; Kiyono, H.; McGhee, J. R.. "Intranasal Il-12 delivery enhances Th2-type while oral Il-12 redirects Th2- to Th1-type responses." Journal of Allergy and Clinical Immunology. Vol. 99, no. 1 PART 2. (January 1997.): S34-.

Boyaka, P. N.; Jackson, R. J.; Marinaro, M.; Vanginkel, F. W.; Kiyono, H.; McGhee, J. R.. "Orally delivered saponin-derived Qs-21 adjuvant elicits systemic and mucosal antibody responses to co-administered protein antigen." Journal of Allergy and Clinical Immunology. Vol. 99, no. 1 PART 2. (January 1997.): S35-.

Lillard, J. W., Jr.; Boyaka, P. N.; Kweon, M.; Yamamoto, M.; Yamamoto, S.; Chertov, O.; Oppenheim, J. J.. "Mucosal administration of defensins with antigen induces Th1- and Il-4 independent-th2 type responses." FASEB Journal. Vol. 12, no. 5. (January 1998.): A909-.

Nguyen, Huan H.; Boyaka, Prosper N.; Moldoveanu, Zina; Novak, Miroslav J.; Kiyono, Hiroshi; McGhee, Jerry R.; Mestecky, Jiri. "Influenza virus-infected epithelial cells present viral antigens to antigen-specific Cd8+ cytotoxic T lymphocytes." Journal of Virology. Vol. 72, no. 5. (January 1998.): 4534-4536.

Nguyen, H, H; Boyaka, P, N; Moldoveanu, Z; Novak, M, J; Kiyono, H; McGhee, J, R; Mestecky, J. "Influenza virus-infected epithelial cells present viral antigens to antigen-specific CD8+ cytotoxic T lymphocytes.." Journal of virology. Vol. 72, no. 5. (January 1998.): 4534-6.

Cormet-Boyaka, Estelle; Huneau, Jean-Francois; Mordrelle, Agnes; Boyaka, Prosper N.; Carbon, Claude; Rubinstein, Ethan; Tome, Daniel. "Secretion of sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors." Antimicrobial Agents and Chemotherapy. Vol. 42, no. 10. (January 1998.): 2607-2611.

Kawabata, Shigetada; Boyaka, Prosper N.; Coste, Michel; Fujihashi, Kohtaro; Yamamoto, Masafumi; McGhee, Jerry R.; Kiyono, Hiroshi. "Intraepithelial lymphocytes from villus tip and crypt portions of the murine small intestine show distinct characteristics." Gastroenterology. Vol. 115, no. 4. (January 1998.): 866-873.

Kawabata, S; Boyaka, P, N; Coste, M; Fujihashi, K; Yamamoto, M; McGhee, J, R; Kiyono, H. "Intraepithelial lymphocytes from villus tip and crypt portions of the murine small intestine show distinct characteristics.." Gastroenterology. Vol. 115, no. 4. (January 1998.): 866-73.

Cormet-Boyaka, E; Huneau, J, F; Mordrelle, A; Boyaka, P, N; Carbon, C; Rubinstein, E; Tome, D. "Secretion of sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors.." Antimicrobial agents and chemotherapy. Vol. 42, no. 10. (January 1998.): 2607-11.

Marinaro, M; Boyaka, P, N; Jackson, R, J; Finkelman, F, D; Kiyono, H; Jirillo, E; McGhee, J R. "Use of intranasal IL-12 to target predominantly Th1 responses to nasal and Th2 responses to oral vaccines given with cholera toxin.." Journal of immunology (Baltimore, Md. : 1950). Vol. 162, no. 1. (January 1999.): 114-21.

Marinaro, M.; Boyaka, P. N.; Jackson, R. J.; Kiyono, H.; McGhee, J. R.. "Mucosal administration of Il-12 to target Th1- or Th2-type responses to mucosal vaccines." Immunology Letters. Vol. 69, no. 1. (January 1999.): 92-93.

Boyaka, Prosper N.; Marinaro, Mariarosaria; Vancott, John L.; Takahashi, Ichiro; Fujihashi, Kohtaro; Yamamoto, Masafumi; Van Ginkel, Frederik W.; Jackson, Raymond J.; Kiyono, Hiroshi; McGhee, Jerry R.. "Strategies for mucosal vaccine development." American Journal of Tropical Medicine and Hygiene. Vol. 60, no. 4 SUPPL.. (January 1999.): 35-45.

Boyaka, Prosper N.; Lillard, James W., Jr.; McGhee, Jerry. "Interleukin 12 and innate molecules for enhanced mucosal immunity." Immunologic Research. Vol. 20, no. 3. (January 1999.): 207-217.

Boyaka, P. N.; Lillard, J. W., Jr.; Jackson, R. J.; van Ginkel, F. W.; Marinaro, M.; Kiyono, H.; McGhee, J. R.. "Endogenous Il-12 regulates mucosal immune responses." Immunology Letters. Vol. 69, no. 1. (January 1999.): 75-.

Boyaka, P, N; Marinaro, M; Vancott, J, L; Takahashi, I; Fujihashi, K; Yamamoto, M; van Ginkel, F, W; Jackson, R, J; Kiyono, H; McGhee, J R. "Strategies for mucosal vaccine development.." The American journal of tropical medicine and hygiene. Vol. 60, no. 4 Suppl. (January 1999.): 35-45.

Boyaka, P, N; Marinaro, M; Jackson, R, J; Menon, S; Kiyono, H; Jirillo, E; McGhee, J R. "IL-12 is an effective adjuvant for induction of mucosal immunity.." Journal of immunology (Baltimore, Md. : 1950). Vol. 162, no. 1. (January 1999.): 122-8.

Boyaka, P, N; Lillard, J W Jr; McGhee, J. "Interleukin 12 and innate molecules for enhanced mucosal immunity.." Immunologic research. Vol. 20, no. 3. (January 1999.): 207-17.

Lillard, James W., Jr.; Boyaka, Prosper N.; Chertov, Oleg; Oppenheim, Joost J.; McGhee, Jerry R.. "Mechanisms for induction of acquired host immunity by neutrophil peptide defensins." Proceedings of the National Academy of Sciences of the United States of America. Vol. 96, no. 2. (January 1999.): 651-656.

Lillard, J. W., Jr.; Boyaka, P. N.; McGhee, J. R.. "Links between innate and adaptive immunity." Immunology Letters. Vol. 69, no. 1. (January 1999.): 75-.

Lillard, J W Jr; Boyaka, P, N; Hedrick, J, A; Zlotnik, A; McGhee, J R. "Lymphotactin acts as an innate mucosal adjuvant.." Journal of immunology (Baltimore, Md. : 1950). Vol. 162, no. 4. (January 1999.): 1959-65.

Lillard, J W Jr; Boyaka, P, N; Chertov, O; Oppenheim, J, J; McGhee, J R. "Mechanisms for induction of acquired host immunity by neutrophil peptide defensins.." Proceedings of the National Academy of Sciences of the United States of America. Vol. 96, no. 2. (January 1999.): 651-6.

Naren, A, P; Di, A; Cormet-Boyaka, E; Boyaka, P, N; McGhee, J, R; Zhou, W; Akagawa, K; Fujiwara, T; Thome, U; Engelhardt, J, F; Nelson, D, J; Kirk, K L. "Syntaxin 1A is expressed in airway epithelial cells, where it modulates CFTR Cl(-) currents.." The Journal of clinical investigation. Vol. 105, no. 3. (January 2000.): 377-86.

Lillard, J. W., Jr.; Boyaka, P. N.; Taub, D. D.; McGhee, J. R.. "Rantes potentiates acquired mucosal immunity." FASEB Journal. Vol. 14, no. 6. (January 2000.): A1204-.

Boyaka, Prosper N.; Wright, Peter F.; Marinaro, Mariarosaria; Kiyono, Hiroshi; Johnson, Joyce E.; Gonzales, Ricardo A.; Ikizler, Mine R.; Werkhaven, Jay A.; Jackson, Raymond J.; Fujihashi, Kohtaro; Di Fabio, Simonetta; Staats, Herman F.; McGhee, Jerry R.. "Human nasopharyngeal-associated lymphoreticular tissues: Functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils." American Journal of Pathology. Vol. 157, no. 6. (January 2000.): 2023-2035.

Boyaka, P. N.; Zagury, D.; Jackson, R. J.; Kiyono, H.; McGhee, J. R.. "Hiv Tat protein regulation of mucosal immunity." Journal of Human Virology. Vol. 3, no. 5. (January 2000.): 257-.

Boyaka, P. N.; Lillard, J. W., Jr.; Mestecky, J.; McGhee, J. R.. "Impaired mucosal immunity in Il-12 knockout mice." FASEB Journal. Vol. 14, no. 6. (January 2000.): A1247-.

Boyaka, P, N; Wright, P, F; Marinaro, M; Kiyono, H; Johnson, J, E; Gonzales, R, A; Ikizler, M, R; Werkhaven, J, A; Jackson, R, J; Fujihashi, K; Di Fabio, S; Staats, H, F; McGhee, J R. "Human nasopharyngeal-associated lymphoreticular tissues. Functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils.." The American journal of pathology. Vol. 157, no. 6. (January 2000.): 2023-35.

Naren, Anjaparavanda P.; Di, Anke; Cormet-Boyaka, Estelle; Boyaka, Prosper N.; McGhee, Jerry R.; Zhou, Weihong; Akagawa, Kimio; Fujiwara, Tomonori; Thome, Ulrich; Engelhardt, John F.; Nelson, Deborah J.; Kirk, Kevin L.. "Syntaxin 1a is expressed in airway epithelial cells, where it modulates Cftr Cl- currents." Journal of Clinical Investigation. Vol. 105, no. 3. (January 2000.): 377-386.

Fujihashi, K; Kato, H; van Ginkel, F, W; Koga, T; Boyaka, P, N; Jackson, R, J; Kato, R; Hagiwara, Y; Etani, Y; Goma, I; Fujihashi, K; Kiyono, H; McGhee, J R. "A revisit of mucosal IgA immunity and oral tolerance.." Acta odontologica Scandinavica. Vol. 59, no. 5. (January 2001.): 301-8.

Lillard, James W., Jr.; Boyaka, Prosper N.; Singh, Shailesh; McGhee, Jerry R.. "Salmonella-mediated mucosal cell-mediated immunity." Cellular and Molecular Biology (Noisy-Le-Grand). Vol. 47, no. 7. (January 2001.): 1115-1120.

Lillard, J W Jr; Boyaka, P, N; Taub, D, D; McGhee, J R. "RANTES potentiates antigen-specific mucosal immune responses.." Journal of immunology (Baltimore, Md. : 1950). Vol. 166, no. 1. (January 2001.): 162-9.

Lillard, J W Jr; Boyaka, P, N; Singh, S; McGhee, J R. "Salmonella-mediated mucosal cell-mediated immunity.." Cellular and molecular biology (Noisy-le-Grand, France). Vol. 47, no. 7. (January 2001.): 1115-20.

Etani, Yuri; McGhee, Jerry R.; Koga, Toshiya; Boyaka, Prosper N.; Fujihashi, Kohtaro. "Impaired mucosal Th1-type immune responses in aged mice." FASEB Journal. Vol. 15, no. 4. (January 2001.): A365-.

Boyaka, P, N; McGhee, J R. "Cytokines as adjuvants for the induction of mucosal immunity.." Advanced drug delivery reviews. Vol. 51, no. 1-3. (January 2001.): 71-9.

Boyaka, Prosper N.; McGhee, Jerry R.. "Cytokines as adjuvants for the induction of mucosal immunity." Advanced Drug Delivery Reviews. Vol. 51, no. 1-3. (January 2001.): 71-79.

Boyaka, Prosper N.; Lillard, James W., Jr.; Jackson, Raymond J.; McGhee, Jerry R.. "Th1 cell regulation of mucosal Iga responses." FASEB Journal. Vol. 15, no. 5. (January 2001.): A1043-.

Boyaka, P, N; Marinaro, M; Jackson, R, J; van Ginkel, F, W; Cormet-Boyaka, E; Kirk, K, L; Kensil, C, R; McGhee, J R. "Oral QS-21 requires early IL-4 help for induction of mucosal and systemic immunity.." Journal of immunology (Baltimore, Md. : 1950). Vol. 166, no. 4. (January 2001.): 2283-90.

Jackson, Raymond J.; Boyaka, Prosper N.; van Ginkel, Frederik W.; Kensil, Charlotte R.; Mcghee, Jerry R.. "Intranasal immunization with Type 3 polysaccharide and Qs-21 or Qs-7 affords protection in mice challenged with S. pneumoniae by the respiratory route." FASEB Journal. Vol. 15, no. 5. (January 2001.): A1189-.

Fujihashi, Kohtaro; Kato, Hirotomo; van Ginkel, Frederik W.; Koga, Toshiya; Boyaka, Prosper N.; Jackson, Raymond J.; Kato, Rie; Hagiwara, Yukari; Etani, Yuri; Goma, Iwao; Fujihashi, Keiko; Kiyono, Hiroshi; McGhee, Jerry R.. "A revisit of mucosal Iga immunity and oral tolerance." Acta Odontologica Scandinavica. Vol. 59, no. 5. (January 2001.): 301-308.

Ben Nasser, Imed; Boyaka, Prosper, N; Fennira Ben Aissa, Fatma; Jeddi, Moncef; Tome, Daniel. "The [173-196] fragment of ovalbumin suppresses ovalbumin-specific rat IgE responses.." International immunopharmacology. Vol. 3, no. 12. (January 2003.): 1569-79.

Ben Nasser, Imed; Boyaka, Prosper N.; Ben Aissa, Fatma Fennira; Jeddi, Moncef; Tome, Daniel. "The (173-196) fragment of ovalbumin suppresses ovalbumin-specific rat Ige responses.." International Immunopharmacology. Vol. 3, no. 12. (January 2003.): 1569-1579.

Lillard, James W., Jr.; Singh, Udai P.; Boyaka, Prosper N.; Singh, Shailesh; Taub, Dennis D.; McGhee, Jerry R.. "Mip-1alpha and Mip-1beta differentially mediate mucosal and systemic adaptive immunity.." Blood. Vol. 101, no. 3. (January 2003.): 807-814.

Lillard, James W Jr; Singh, Udai, P; Boyaka, Prosper, N; Singh, Shailesh; Taub, Dennis, D; McGhee, Jerry R. "MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity.." Blood. Vol. 101, no. 3. (January 2003.): 807-14.

Boyaka, Prosper, N; Tafaro, Angela; Fischer, Romy; Leppla, Stephen, H; Fujihashi, Kohtaro; McGhee, Jerry R. "Effective mucosal immunity to anthrax: neutralizing antibodies and Th cell responses following nasal immunization with protective antigen.." Journal of immunology (Baltimore, Md. : 1950). Vol. 170, no. 11. (January 2003.): 5636-43.

Boyaka, Prosper, N; Tafaro, Angela; Fischer, Romy; Fujihashi, Kohtaro; Jirillo, Emilio; McGhee, Jerry R. "Therapeutic manipulation of the immune system: enhancement of innate and adaptive mucosal immunity.." Current pharmaceutical design. Vol. 9, no. 24. (January 2003.): 1965-72.

Boyaka, Prosper, N; Ohmura, Mari; Fujihashi, Kohtaro; Koga, Toshiya; Yamamoto, Masafumi; Kweon, Mi-Na; Takeda, Yoshifumi; Jackson, Raymond, J; Kiyono, Hiroshi; Yuki, Yoshikazu; McGhee, Jerry R. "Chimeras of labile toxin one and cholera toxin retain mucosal adjuvanticity and direct Th cell subsets via their B subunit.." Journal of immunology (Baltimore, Md. : 1950). Vol. 170, no. 1. (January 2003.): 454-62.

Boyaka, Prosper N.; Tafaro, Angela; Fischer, Romy; Leppla, Stephen H.; Jackson, Raymond J.; Fujihashi, Kohtaro; McGhee, Jerry R.. "Neutralizing antibodies and T helper cell responses following nasal immunization with anthrax protective antigen.." FASEB Journal. Vol. 17, no. 7. (January 2003.): C320-.

Boyaka, Prosper N.; Tafaro, Angela; Fischer, Romy; Leppla, Stephen H.; Fujihashi, Kohtaro; McGhee, Jerry R.. "Effective mucosal immunity to anthrax: Neutralizing antibodies and Th cell responses following nasal immunization with protective antigen.." Journal of Immunology. Vol. 170, no. 11. (January 2003.): 5636-5643.

Jackson, Raymond John; van Ginkel, Frederik W.; Boyaka, Prosper N.; McGhee, Jerry R.. "A link between upregulation of nerve growth factor and cholera toxin adjuvanticity.." FASEB Journal. Vol. 17, no. 7. (January 2003.): C232-.

Boyaka, Prosper N.; Tafaro, Angela; Fischer, Romy; Fujihashi, Kohtaro; Jirillo, Emilio; McGhee, Jerry R.. "Therapeutic manipulation of the immune system: Enhancement of innate and adaptive mucosal immunity.." Current Pharmaceutical Design. Vol. 9, no. 24. (January 2003.): 1965-1972.

Boyaka, Prosper N.; Ohmura, Mari; Fujihashi, Kohtaro; Koga, Toshiya; Yamamoto, Masafumi; Kweon, Mi-Na; Takeda, Yoshifumi; Jackson, Raymond J.; Kiyono, Hiroshi; Yuki, Yoshikazu; McGhee, Jerry R.. "Chimeras of labile toxin one and cholera toxin retain mucosal adjuvanticity and direct Th cell subsets via their B subunit.." Journal of Immunology. Vol. 170, no. 1. (January 2003.): 454-462.

Tafaro, Angela; McGhee, Jerry R.; Fischer, Romy; Jackson, Raymond J.; Leppla, Stephen H.; Boyaka, Prosper N.. "Protective immunity to a combined spore and protective antigen nasal anthrax vaccine.." FASEB Journal. Vol. 17, no. 7. (January 2003.): C324-.

Fischer, Romy; McGhee, Jerry R.; Vu, Huong L.; Jackson, Raymond J.; Tome, Daniel; Boyaka, Prosper N.. "Airway inflammation and cytokine responses in mouse models of peanut allergy.." FASEB Journal. Vol. 17, no. 7. (January 2003.): C249-C250.

Sfeir, Rose Mary; Dubarry, Michel; Boyaka, Prosper, N; Rautureau, Michele; Tome, Daniel. "The mode of oral bovine lactoferrin administration influences mucosal and systemic immune responses in mice.." The Journal of nutrition. Vol. 134, no. 2. (January 2004.): 403-9.

Singh, Udai, P; Singh, Shailesh; Boyaka, Prosper, N; McGhee, Jerry, R; Lillard, James W Jr. "Granulocyte chemotactic protein-2 mediates adaptive immunity in part through IL-8Rbeta interactions.." Journal of leukocyte biology. Vol. 76, no. 6. (January 2004.): 1240-7.

Singh, Udai P.; Singh, Shailesh; Boyaka, Prosper N.; McGhee, Jerry R.; Lillard, James W. Jr. "Granulocyte chemotactic protein-2 mediates adaptive immunity in part through Il-8rbeta interactions." Journal of Leukocyte Biology. Vol. 76, no. 6. (January 2004.): 1240-1247.

Lifrani, Awatif; Dubarry, Michel; Rautureau, Michele; Aattouri, Najat; Boyaka, Prosper N.; Tome, Daniel. "Peanut-lupine antibody cross-reactivity is not associated to cross-allergenicity in peanut-sensitized mouse strains." International Immunopharmacology. Vol. 5, no. 9. (January 2005.): 1427-1435.

Fischer, Romy; McGhee, Jerry R.; Vu, Huong Lan; Atkinson, T. Prescott; Jackson, Raymond J.; Tome, Daniel; Boyaka, Prosper N.. "Oral and nasal sensitization promote distinct immune responses and lung reactivity in a mouse model of peanut allergy." American Journal of Pathology. Vol. 167, no. 6. (January 2005.): 1621-1630.

Ben Nasser, Imed; Fennira-Ben Aissa, Fatma; Boyaka, Prosper, N; Jeddi, Moncef; Tome, Daniel. "Prior exposure to the carrier regulates rat immune responses to a conjugate vaccine.." International immunopharmacology. Vol. 5, no. 11. (January 2005.): 1633-40.

Ben Nasser, Imed; Fennira-ben Aissa, Fatma; Boyaka, Prosper N.; Jeddi, Moncef; Tome, Daniel. "Prior exposure to the carrier regulates rat immune responses to a conjugate vaccine." International Immunopharmacology. Vol. 5, no. 11. (January 2005.): 1633-1640.

Fischer, Romy; Debbabi, Hajer; Dubarry, Michel; Boyaka, Prosper; Tome, Daniel. "Regulation of physiological and pathological Th1 and Th2 responses by lactoferrin." Biochemistry and Cell Biology. Vol. 84, no. 3. (January 2006.): 303-311.

Fischer, Romy; Tome, Daniel; Boyaka, Prosper N.. "Th1 and Th2 cells are both required in mice eosinophil- and neutrophil-associated asthma models." FASEB Journal. Vol. 20, no. 4, Part 1. (January 2006.): A212-A213.

Boyaka, Prosper N.; Duverger, Alexandra; Tang, Wei-Jen; Fujihashi, Kohtaro; McGhee, Jerry R.; Leppla, Stephen H.. "A novel method for delivery of regulatory molecules in the Gi tract using Bacillus anthracis protective antigen." Journal of Immunology. Vol. 176, no. Suppl. S. (January 2006.): S243-.

Hagiwara, Yukari; Kawamura, Yuki I.; Kataoka, Kosuke; Rahima, Bibi; Jackson, Raymond J.; Komase, Katsuhiro; Dohi, Taeko; Boyaka, Prosper N.; Takeda, Yoshifumi; Kiyono, Hiroshi; McGhee, Jerry R.; Fujihashi, Kohtaro. "A second generation of double mutant cholera toxin adjuvants: Enhanced immunity without intracellular trafficking." Journal of Immunology. Vol. 177, no. 5. (January 2006.): 3045-3054.

Duverger, Alexandra; Leppla, Stephen H.; Tang, Wei-Jen; Fujihashi, Kohtaro; Kiyono, Hiroshi; Mcghee, Jerry R.; Boyaka, Prosper N.. "Bacillus anthracis edema toxin acts as an adjuvant for enhanced immunity to Pa and to unrelated vaccine antigens co-administered by the nasal or the transcutaneous route." Journal of Immunology. Vol. 176, no. Suppl. S. (January 2006.): S115-.

Duverger, Alexandra; Jackson, Raymond J.; van Ginkel, Frederick W.; Fischer, Romy; Tafaro, Angela; Leppla, Stephen H.; Fujihashi, Kohtaro; Kiyono, Hiroshi; McGhee, Jerry R.; Boyaka, Prosper N.. "Bacillus anthracis edema toxin acts as an adjuvant for mucosal immune responses to nasally administered vaccine antigens." Journal of Immunology. Vol. 176, no. 3. (January 2006.): 1776-1783.

Fischer, Romy; Tome, Daniel; McGhee, Jerry R.; Boyaka, Prosper N.. "Th1 and Th2 cells are required for both eosinophil- and neutrophil-associated airway inflammatory responses in mice." Biochemical and Biophysical Research Communications. Vol. 357, no. 1. (January 2007.): 44-49.

Fischer, Romy; Debbabi, Hajer; Blais, Anne; Dubarry, Michel; Rautureau, Michele; Boyaka, Prosper N.; Tome, Daniel. "Uptake of ingested bovine lactoferrin and its accumulation in adult mouse tissues." International Immunopharmacology. Vol. 10, (January 2007.): 1387-1393.

Youn, Hyun-Jun; Ko, Sung-Youl; Lee, Kyoo-A.; Ko, Hyun-Jeong; Lee, Yoon-Sook; Fujihashi, Kohtaro; Boyaka, Prosper N.; Kim, Sang-Hee; Horimoto, Taisuke; Kweon, Mi-Na; Kang, Chang-Yuil. "A single intranasal immunization with inactivated influenza virus and alpha-galactosylceramide induces long-term protective immunity without redirecting antigen to the central nervous system." Vaccine. Vol. 25, no. 28. (January 2007.): 5189-5198.

Rennolds, J; Boyaka, PN; Bellis, SL; Cormet-Boyaka, E. "Low temperature induces the delivery of mature and immature CFTR to the plasma membrane.." Biochem Biophys Res Commun. (January 2008.): -.

 

Professional Activities

2009 - present National Instutite of Health, Immunity and Host Defense Study Section.
2004 - 2009 National Institute of Health.