Center for Microbial Pathogenesis
700 Children's Drive, W410
Columbus, OH 43026
Phone: (614) 722-2764
Associate Professor, Pediatrics
Assistant Professor, Pediatrics
Associate Professor, SBS-Microbial Infectn/Immunity
Adjunct Associate Professor, Biosciences
|2013 - present||Jeffrey Galley, The Ohio State University.|
|2011 - 2013||Robert Easterling, The Ohio State University. Graduated 2013. Characterization of colonic macrophages in mice exposed to a social stressor during oral challenge with Citrobacter rodentium.|
Michael T. Bailey, David A. Padgett, and John F. Sheridan. "Stress-induced modulation of innate resistance and adaptive immunity to influenza viral infection.." In Psychoneuroimmunology. 4 ed. Vol. 2. Edited by Robert Ader. 1097-1106. Burlington, MA, US|USA: Elsevier Academic Press, January 2007.
Michael T. Bailey and Ronald Glaser. "Immune measures in behavioral medicine research: procedures and implications." In Handbook of Behavioral Medicine: Methods and Applications. Edited by Andrew Steptoe. -. New York, US|USA: Springer Publishers, January 2010.
Michael T. Bailey. "Stress, immunity, and the effects on the indigenous microflora.." In Microbial Endocrinology. Edited by Primrose Freestone and Mark Lyte. -. New York, US|USA: Springer Publishers, January 2010.
Mays JW, Powell ND, Bailey MT, Sheridan JF. "Environmental Challenges and the Neuroendocrine Mechanisms of Stress-Induced Modulation of Host Resistance to Microbial Infection." In Eco-Immunology. Edited by G. Demas and R.J. Nelson. -. New York: Oxford University Press, January 2012.
|1995||A.A.S., Winona State University|
|1997||B.S.C.E., Minnesota State University Mankato|
|2002||B.F.A., University of Wisconsin|
|2008 - present||Physiology and Behavior (15 manuscripts)|
|2009 - present||World Journal of Gastrointestinal Pathophysiology|
|2010 - present||Gastroenterology (2 manuscripts)|
|2010 - present||World Journal of Gastroenterology (2 manuscripts)|
|2010 - present||International Journal of Neuropharmacology (2 manuscripts)|
|2010 - present||World Journal of Gastrointestinal Pathophysiology|
|2011 - present||ISRN Inflammation|
|2011 - present||World Journal of Gastrointestinal Pathophysiology (2 manuscripts)|
|2012 - present||Nature Reviews Neuroscience|
|2012 - present||BMC Physiology|
|2012 - present||Frontiers in Molecular Immunology|
|2012 - present||Future Medicine|
|2012||Robert Ader New Investigator Award. PsychoNeuroImmunology Research Society.|
Kinsey SG; Bailey MT; Sheridan JF; Padgett DA; Avitstur R. "Repeated social defeat causes increased anxiety-like behavior and alters splenocyte function in C57BL/6 and CD-1 mice." Brain, Behavior, and Immunity. Vol. 21, no. 4. (May 2007.): 458-466.
Avitsur R; Kinsey SG; Bidor K; Bailey MT; Padgett DA; Sheridan JF. "Subordinate social status modulates the vulnerability to the immunological effects of social stress." Psychoneuroendocrinology. Vol. 32, no. 8-10. (September 2007.): 1097-1105.
Bailey MT; Engler H; Powell ND; Padgett DA; Sheridan JF. "Repeated social defeat increases the bactericidal activity of splenic macrophages through a Toll-like receptor-dependent pathway." American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Vol. 293, no. 3. (September 2007.): R1180-R1190.
Engler H; Bailey MT; Engler A; Stiner-Jones LM; Quan N; Sheridan JF.. "Interleukin-1 receptor type 1-deficient mice fail to develop social stress-associated glucocorticoid resistance in the spleen." Psychoneuroendocrinology. Vol. 33, no. 1. (January 2008.): 108-117.
Kinsey SG; Bailey MT; Sheridan JF; Padgett DA.. "The inflammatory response to social defeat is increased in older mice." Physiology and Behavior. Vol. 93, no. 3. (February 2008.): 628-636.
Henry CJ; Huang Y; Wynne A; Hanke M; Himler J; Bailey MT; Sheridan JF; Godbout JP. "Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia." Journal of Neuroinflammation. Vol. 5, (May 2008.): 15-.
Martin LB; Navarra KJ; Bailey MT; Hutch CR; Powell ND; Sheridan JF; Nelson RJ. "Food restriction compromises immune memory in deer mice (Peromyscus maniculatus) by reducing spleen-derived antibody-producing B cell numbers." Physiological and Biochemical Zoology. Vol. 81, no. 3. (May 2008.): 366-372.
Powell ND; Bailey MT; Mays JW; Stiner-Jones LM; Hanke ML; Padgett DA; Sheridan JF. "Repeated social defeat activates dendritic cells and enhances Toll-like receptor dependent cytokine secretion." Brain, Behavior, And Immunity. Vol. 23, no. 2. (February 2009.): 225-231.
Bailey MT; Kinsey SG; Padgett DA; Sheridan JF; Leblebicioglu B. "Social stress enhances IL-1beta and TNF-alpha production by Porphyromonas gingivalis lipopolysaccharide-stimulated CD11b+ cells." Physiology & Behavior. Vol. 98, no. 3. (September 2009.): 351-358.
Bailey MT; Kierstein S; Sharma S; Spaits M; Kinsey SG; Tliba O; Sheridan JF; Panettieri RA; Haczku A. "Social stress enhances allergen-induced airway inflammation in mice and inhibits corticosteroid responsiveness of cytokine production." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 182, no. 12. (June 2009.): 7888-7896.
Curry JM, Hanke ML, Piper MG, Bailey MT, Bringardner BD, Sheridan JF, Marsh CB.. "Social disruption induces lung inflammation." Brain, Behavior, and Immunity. Vol. 24, no. 3. (March 2010.): 394-402.
Belevych N; Buchanan K; Chen Q; Bailey M; Quan N. "Location-specific activation of the paraventricular nucleus of the hypothalamus by localized inflammation." Brain, Behavior, and Immunity. Vol. 24, no. 7. (October 2010.): 1137-1147.
Mays JW, Bailey MT, Hunzeker JT, Powell ND, Papenfuss T, Karlsson EA, Padgett DA, Sheridan JF. "Influenza virus-specific immunological memory is enhanced by repeated social defeat." Journal of Immunology. Vol. 184, no. 4. (February 2010.): 2014-2025.
Bailey MT, Walton JC, Dowd SE, Weil ZM, and Nelson RJ. "Photoperiod modulates gut bacteria composition in male Siberian hamsters (Phodopus sangorus)." Brain, Behavior, and Immunity. Vol. 24, no. 4. (May 2010.): 577-584.
Bailey MT. "The effects of psychological stressors on the intestinal microbiota.." Bioscience and Microflora. Vol. 28, no. 4. (January 2010.): 119-124.
Dong-Newsom P, Powell ND, Bailey MT, Padgett DA, Sheridan JF.. "Repeated social stress enhances the innate immune response to a primary HSV-1 infection in the cornea and trigeminal ganglia of Balb/c mice." Brain, Behavior, and Immunity. Vol. 24, no. 2. (February 2010.): 273-280.
Bailey MT, Dowd SE, Parry NMA, Galley JD, Schauer DB, and Lyte M.. "Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by Citrobacter rodentium." Infection and Immunity. Vol. 78, no. 4. (April 2010.): 1509-1519.
Lin,Y; Roman,K; Foust,K,D; Kaspar,B,K; Bailey,M,T; Stephens,R,L. "Glutamate Transporter GLT-1 Upregulation Attenuates Visceral Nociception and Hyperalgesia via Spinal Mechanisms Not Related to Anti-Inflammatory or Probiotic Effects." Pain research and treatment. Vol. 2011, (January 2011.): 507029-?.
Powell ND; Mays JW; Bailey MT; Hanke ML; Sheridan JF.. "Immunogenic dendritic cells primed by social defeat enhance adaptive immunity to influenza A virus." Brain, Behavior, and Immunity. Vol. 25, no. 1. (January 2011.): 46-52.
Powell ND, Allen RG, Hufnagle AR, Sheridan JF, and Bailey MT. "Stressor-Induced Alterations of Adaptive Immunity to Vaccination and Viral Pathogens." Immunology and Allergy Clinics of North America. Vol. 31, no. 1. (February 2011.): 69-79.
Bailey MT; Dowd SE; Galley JD; Hufnagle AR; Allen RG; Lyte M.. "Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation." Brain, Behavior, and Immunity. Vol. 25, no. 3. (March 2011.): 397-407.
Wohleb ES; Hanke ML; Corona AW; Powell ND; Stiner LM; Bailey MT; Nelson RJ; Godbout JP; Sheridan JF.. "beta-adrenergic receptor antagonism prevents anxiety-like behavior and microglial reactivity induced by repeated social defeat." Journal of Neuroscience. Vol. 31, no. 17. (April 2011.): 6277-6288.
Hanke, ML, Powell, ND, Stiner-Jones, LM, Bailey, MT, and Sheridan, JF. "Beta adrenergic blockade decreases the immunomodulatory effects of social disruption stress." Brain, Behavior, and Immunity. Vol. 26, no. 7. (October 2012.): 1150-1159.
Mays,Jacqueline,W; Powell,Nicole,D; Hunzeker,John,T; Hanke,Mark,L; Bailey,Michael,T; Sheridan,John,F. "Stress and the anti-influenza immune response: Repeated social defeat augments clonal expansion of CD8(+)T cells during primary influenza A viral infection." JOURNAL OF NEUROIMMUNOLOGY. Vol. 243, no. 1-2. (February 2012.): 34-42.
Allen,Rebecca,G; Lafuse,William,P; Galley,Jeffrey,D; Ali,Mohamed,M; Ahmer,Brian,MM; Bailey,Michael,T. "The intestinal microbiota are necessary for stressor-induced enhancement of splenic macrophage microbicidal activity." BRAIN BEHAVIOR AND IMMUNITY. Vol. 26, no. 3. (March 2012.): 371-382.
Bailey, MT. "The contributing role of the intestinal microbiota in stressor-induced increases in susceptibility to enteric infection and systemic immunomodulation." Hormones and Behavior. Vol. 62, no. 3. (August 2012.): 286-294.
Bailey, MT.. "Stress, asthma, and infection: putting the pieces together.." Brain, Behavior, and Immunity. Vol. 29, (March 2013.): 9-10.
Mackos AR, Galley JD, Eubank TD, Easterling RS, Parry NM, Fox JG, Lyte M, Bailey MT. "ocial stress-enhanced severity of Citrobacter rodentium-induced colitis is CCL2-dependent and attenuated by probiotic Lactobacillus reuteri." Mucosal Immunology. Vol. 9, (September 2015.): 515-526.
Tarr AJ, Galley JD, Fisher SE, Chichlowski M, Berg BM, Bailey MT. "The prebiotics 3’Sialyllactose and 6’Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: Evidence for effects on the gut-brain axis." Brain, Behavior, and Immunity. Vol. 50, (November 2015.): 166-177.
Gur TL, Bailey MT. "Effects of Stress on Commensal Microbes and Immune System Activity." Microbial Endocrinology: Interkingdom Signaling in Infectious Disease and Health. Vol. 14, (March 2016.): 289-300.
Bailey MT. "Psychological Stress, Immunity, and the Effects on Indigenous Microflora." Microbial Endocrinology: Interkingdom Signaling in Infectious Disease and Health. Vol. 11, (February 2016.): 225-246.
Xu J, Galley JD, Bailey MT, Thomas-Ahner JM, Clinton SK, Olivo-Marston SE. "The Impact of Dietary Energy Intake Early in Life on the Colonic Microbiota of Adult Mice." Scientific Reports. Vol. 6, (January 2016.): 19083-.
Mackos, AR, Eubank, TD, Parry, NM, Bailey, MT. "Probiotic Lactobacillus reuteri attenuates the stressor-enhanced severity of Citrobacter rodentium infection." Infection and Immunity. -.
|January 2010||Allen RG, Stiner-Jones LM, Sheridan JF, and Bailey MT.."Stress-induced increases in bacterial killing are p38dependent" . : 94.9|
|January 2010||Bailey MT; Galley JD; Dowd SE; Lyte M.."Stressor exposure significantly changes the composition of the intestinal microbiota and leads to increased Citrobacter rodentium colonization and colonic inflammatory responses" .|
|January 2010||Bailey MT, Galley JD, Dowd SE, Lyte M."The stress response significantly changes microbial populations in the intestines and increases susceptibility to enteric infection" .|
|January 2011||Kapoor A; Bailey MT; Dowd S; Coe C.."Social factors affect the composition of the intestinal microbiome" .|
|January 2011||Bailey MT; Allen RG; Galley JD; Hufnagle AR; Lyte M.."Novel role for the intestinal microbiota in stressor-induced immunopotentiation" .|
|January 2011||Bailey MT, Galley JD, Hufnagle AR, Allen RG, Dowd SE, Parry NM, Lyte M."Stressor-induced reduction of commensal Lactobacillus reuteri enhances colonic inflammation upon oral challenge with the murine colonic pathogen Citrobacter rodentium" .|
|October 2012||Galley, JD, Mackos, AR, Parry NM, Nelson, M, Yu, Z, Kumar, PS, Bailey, MT."Stressor induced reduction in murine-associated Lactobacillus reuteri results in increased colonic inflammation when challenged with Citrobacter rodentium." San Antonio.|
|February 2013||Mackos, AR, Galley, JD, Parry, NM, Eubank, TD, and Bailey, MT."CCL2 is necessary for stressor-induced exacerbation of infectious colitis and is a key player in host-microbiota interactions" Taos.|
|February 2013||Mackos, AR, Eubank, TD, Parry, NM, and Bailey, MT.."Probiotic intervention can reverse stressor-enhanced colonic barrier disruptions" Columbus.|
|April 2013||Mackos, AR, Galley, JD, Eubank, TD, Parry, NM, and Bailey, MT.."Inflammatory monocytes are necessary for stressor-exacerbated infectious colitis." Columbus.|
|April 2013||Galley, JD, Mackos, AR, Parry, NM, Nelson, Ml, Yu, Z, Kumar, PS, and Bailey, MT.."Stressor exposure significantly disrupts the colonic microbiota, resulting in increased inflammation when challenged by an enteric pathogen." Columbus.|
|April 2013||Galley, JD, Mackos, AR, Parry, NM, Nelson, M, Yu, Z, Kumar, PS, Bailey, MT.."Exposure to a social stressor disrupts the community structure of the colonic microbiota and increases the severity of an enteric infection." Columbus.|
|April 2013||Galley, JD, Mackos, AR, Parry, NM, Nelson, M, Yu, Z, Kumar, PS, and Bailey, MT.."Stressor exposure shifts the colonic microbiota community structure and exacerbates an enteric infection." Columbus.|
|May 2013||Mackos, AR, Eubank, TD, Parry, NM, and Bailey, MT."Probiotic intervention can reverse stressor-enhanced colonic barrier disruptions during Citrobacter rodentium challenge" Columbus.|
"Stress, immunity, and natural defenses: learning from animal studies and from human trials." Presented at Scientific Meeting on Stress, Immunity, and Actimel, London, GB|GBR. (October 2007)
"Impact of psychological stress on microflora of the gut." Presented at Digestive Disease Week, San Diego, US|USA. (May 2008)
"Stress and intestinal microbiota." Presented at Yakult Bio-Science Foundation 17th Symposium on Intestinal Flora (Microbiota): Intestinal Microbiota and Functional Gastrointestinal Disorders, Tokyo, JP|JPN. (October 2008)
"Stress-induced enhancement of the host inflammatory response: implications for susceptibility and resistance to infectious diseases." Presented at M.I.T. Veterinary Biosciences Group Meeting, Cambridge, MA, US|USA. (January 2009)
"Impact of stressor exposure on intestinal microbiota.." Presented at Society for Integrative and Comparative Biology special symposium entitled "Eco-Immunology meets Psycynoreuroimmunology", Boston, MA, US|USA. (January 2009)
"Stress-induced alterations of the immune response: implications for susceptibility and resistance to infectious diseases." Presented at Stress in Livestock, Chicago, IL, US|USA. (January 2009)
"The stress response significantly changes microbial populations in the intestines and increases susceptibility to enteric infection." Presented at Digestive Disease Week, New Orleans, LA, US|USA. (May 2010)
"Novel role for the intestinal microbiota in stressor-induced immunopotentiation." Presented at PsychoNeuroImmunology Research Society Annual Meeting, Chicago, IL, US|USA. (June 2011)
"Microbiota influences on mucosal and systemic inflammatory responses: Implications for stressor-induced immunomodulation." Presented at Society for Leukocyte Biology, Kansas City, MO, US|USA. (September 2011)
"Exposure to a social stressor alters the structure of the intestinal microbiota." Presented at SGV 2011, Basel, CH|CHE. (November 2011)
"The Robert Ader New Investigator Award Lecture: The intestinal microbiota are interactively involved in stressor-induced immunomodulation." Presented at The PsychoNeuroImmunology Research Society's Annual Meeting, San Diego, CA, US|USA. (June 2012)
"Impact of the intestinal microbiota on mucosal and systemic inflammatory responses." Presented at Nationwide Children's Hospital, Columbus, OH, US|USA. (May 2012)
"Impact of the stress response on the intestinal microbiota: implications for stressor-induced immunomodulation." Presented at Kent State University, Kent, OH, US|USA. (April 2012)
"Impact of stressor exposure on the intestinal microbiota: implications for stressor-induced immunomodulation.." Presented at Department of Integrative Physiology Colloquium Series, Boulder, CO, US|USA. (December 2012)
"Stressor exposure influences the microbial composition of the gut.." Presented at The Gut-Brain Axis: Co-Development and Function., San Francisco, CA, US|USA. (October 2012)
"Interactions between diet and the intestinal microbiota: implications for obesity." Presented at 2nd Annual Ohio Academy of Nutrition and Dietetics Conference and Exhibition., Columbus, US|USA. (May 2013)
"The effect of external stressors on gut microbiota composition and function." Presented at American Psychosomatic Society-American Gastroenterological Association Symposium on Brain-Gut Interactions and the Intestinal Microenvironment, New York, NY, US|USA. (September 2015)
"Stress and the Commensal Microbiota: Implications for Host Immunity and the Gut-Brain Axis." Presented at Indiana University Behavior Colloquia, Bloomington, IN, US|USA. (October 2015)
|2007 - present||Danone, UK.|
|2009 - present||Consulting. Pfizer Animal Health. Chicago, IL.|
|2009||Israeli Science Foundation. Israeli Science Foundation.|
|2009 - 2010||National Science Foundation. National Science Foundation.|