460 W 12th Ave
Columbus, OH 43210
Email: drew.47@osu.edu
Current OSU Appointment
Assistant Professor, SBS-Microbial Infectn/Immunity
Advising Narrative
Graduated with Research DistinctionWrote and defended Honors Thesis entitled "Validation of Three Deubiquitinating Proteases in Plasmodium falciparum as Putative Drug Targets"
Chapters in Books
James C. Morris, Zefeng Wang, Shawn A. Motyka, Mark E. Drew, Paul T. Englund. "An RNAi-based genomic library for forward genetics in the African trypanosome." In Gene Silencing by RNA Interference: Technology and Application. Edited by M. Sohail. -. Boca Raton, FL, US|USA: CRC Press, January 2004.
Mark E. Drew, Shawn A. Motyka, James C. Morris, Zefeng Wang, Paul T. Englund. "Inducible RNAi as a forward genetic tool in Trypanosoma brucei." In RNA Interference Technology. Edited by K. Appasani. 247-256. Cambridge: Cambridge University Press, January 2005.
Journal Articles
Langford, C, K; Kavanaugh, M, P; Stenberg, P, E; Drew, M, E; Zhang, W; Landfear, S M. "Functional expression and subcellular localization of a high-Km hexose transporter from Leishmania donovani.." Biochemistry. Vol. 34, no. 37. (January 1995.): 11814-21.
Drew, M, E; Langford, C, K; Klamo, E, M; Russell, D, G; Kavanaugh, M, P; Landfear, S M. "Functional expression of a myo-inositol/H+ symporter from Leishmania donovani.." Molecular and cellular biology. Vol. 15, no. 10. (January 1995.): 5508-15.
Feagin, J, E; Drew, M E. "Plasmodium falciparum: alterations in organelle transcript abundance during the erythrocytic cycle.." Experimental parasitology. Vol. 80, no. 3. (January 1995.): 430-40.
Klamo, E, M; Drew, M, E; Landfear, S, M; Kavanaugh, M P. "Kinetics and stoichiometry of a proton/myo-inositol cotransporter.." The Journal of biological chemistry. Vol. 271, no. 25. (January 1996.): 14937-43.
Vasudevan, G; Carter, N, S; Drew, M, E; Beverley, S, M; Sanchez, M, A; Seyfang, A; Ullman, B; Landfear, S M. "Cloning of Leishmania nucleoside transporter genes by rescue of a transport-deficient mutant.." Proceedings of the National Academy of Sciences of the United States of America. Vol. 95, no. 17. (January 1998.): 9873-8.
Wang, Z; Morris, J, C; Drew, M, E; Englund, P T. "Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters.." The Journal of biological chemistry. Vol. 275, no. 51. (January 2000.): 40174-9.
Carter, N, S; Drew, M, E; Sanchez, M; Vasudevan, G; Landfear, S, M; Ullman, B. "Cloning of a novel inosine-guanosine transporter gene from Leishmania donovani by functional rescue of a transport-deficient mutant.." The Journal of biological chemistry. Vol. 275, no. 27. (January 2000.): 20935-41.
Klingbeil, M, M; Drew, M, E; Liu, Y; Morris, J, C; Motyka, S, A; Saxowsky, T, T; Wang, Z; Englund, P T. "Unlocking the secrets of trypanosome kinetoplast DNA network replication.." Protist. Vol. 152, no. 4. (January 2001.): 255-62.
Morris, J, C; Wang, Z; Drew, M, E; Paul, K, S; Englund, P T. "Inhibition of bloodstream form Trypanosoma brucei gene expression by RNA interference using the pZJM dual T7 vector.." Molecular and biochemical parasitology. Vol. 117, no. 1. (January 2001.): 111-3.
Morris, J, C; Drew, M, E; Klingbeil, M, M; Motyka, S, A; Saxowsky, T, T; Wang, Z; Englund, P T. "Replication of kinetoplast DNA: an update for the new millennium.." International journal for parasitology. Vol. 31, no. 5-6. (January 2001.): 453-8.
Abu-Elneel, K; Robinson, D, R; Drew, M, E; Englund, P, T; Shlomai, J. "Intramitochondrial localization of universal minicircle sequence-binding protein, a trypanosomatid protein that binds kinetoplast minicircle replication origins.." The Journal of cell biology. Vol. 153, no. 4. (January 2001.): 725-34.
Drew, M, E; Englund, P T. "Intramitochondrial location and dynamics of Crithidia fasciculata kinetoplast minicircle replication intermediates.." The Journal of cell biology. Vol. 153, no. 4. (January 2001.): 735-44.
Wang, Zefeng; Drew, Mark, E; Morris, James, C; Englund, Paul T. "Asymmetrical division of the kinetoplast DNA network of the trypanosome.." The EMBO journal. Vol. 21, no. 18. (January 2002.): 4998-5005.
Grams, Jayleen; Morris, James, C; Drew, Mark, E; Wang, Zefeng; Englund, Paul, T; Hajduk, Stephen L. "A trypanosome mitochondrial RNA polymerase is required for transcription and replication.." The Journal of biological chemistry. Vol. 277, no. 19. (January 2002.): 16952-9.
Morris, James, C; Wang, Zefeng; Drew, Mark, E; Englund, Paul T. "Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library.." The EMBO journal. Vol. 21, no. 17. (January 2002.): 4429-38.
Drew, Mark, E; Morris, James, C; Wang, Zefeng; Wells, Lance; Sanchez, Marco; Landfear, Scott, M; Englund, Paul T. "The adenosine analog tubercidin inhibits glycolysis in Trypanosoma brucei as revealed by an RNA interference library.." The Journal of biological chemistry. Vol. 278, no. 47. (January 2003.): 46596-600.
Liu, Jun; Gluzman, Ilya, Y; Drew, Mark, E; Goldberg, Daniel E. "The role of Plasmodium falciparum food vacuole plasmepsins.." The Journal of biological chemistry. Vol. 280, no. 2. (January 2005.): 1432-7.
Motyka, Shawn, A; Drew, Mark, E; Yildirir, Gokben; Englund, Paul T. "Overexpression of a cytochrome b5 reductase-like protein causes kinetoplast DNA loss in Trypanosoma brucei.." The Journal of biological chemistry. Vol. 281, no. 27. (January 2006.): 18499-506.
Drew, Mark, E; Banerjee, Ritu; Uffman, Eric, W; Gilbertson, Scott; Rosenthal, Philip, J; Goldberg, Daniel E. "Plasmodium food vacuole plasmepsins are activated by falcipains.." The Journal of biological chemistry. Vol. 283, no. 19. (January 2008.): 12870-6.
Drew,Mark,E; Banerjee,Ritu; Uffman,Eric,W; Gilbertson,Scott; Rosenthal,Philip,J; Goldberg,Daniel,E. "Plasmodium food vacuole plasmepsins are activated by falcipains." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 283, no. 19. (May 2008.): 12870-12876.
Bahar M, Deng Y, Zhu X, He S, Pandharkar T, Drew ME, Navarro-Vázquez A, Anklin C, Gil RR, Doskotch RW, Werbovetz KA, Kinghorn AD. "Potent antiprotozoal activity of a novel semi-synthetic berberine derivative." Bioorganic and Medicinal Chemistry Letters. Vol. 9, no. 21. (May 2011.): 2606-2610.
He S, Werbovetz KA, Drew ME. "The induction of oxidative stress in T. brucei by the antitrypanosomal dihydroquinolone OSU-40." Antimicrobial Agents and Chemotherapy. (February 2012.): -.
Abandeh FI, Drew ME, Sopirala MM. "Carbapenem-Hydrolyzing Gram-Negative Bacteria: Current Options for Treatment and Review of Drugs in Development." Recent Patents on Anti-Infective Drug Discovery. (January 2012.): -.