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Larry Schlesinger, MD


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460 W 12th Ave
Columbus, OH 43210

Phone: (614) 293-5666

Email: schlesinger.17@osu.edu

 

Current OSU Appointments

Chair, SBS-Microbial Infectn/Immunity

Professor, SBS-Molec Vir, Imm & Med Gen

Professor, Microbiology Admin

Director-00, R-Ed Administration

Professor, COPH -Environmental Health Sci

 

Biographical

Larry S. Schlesinger, MD, Samuel Saslaw Professor of Medicine is Chair of the Department of Microbial Infection and Immunity, and Director of the Center for Microbial Interface Biology. He also directs the Medical Scientist Training Program (MD/PhD). He has joint appointments in the College of Public Health and Departments of Microbiology, Veterinary Biosciences, and Molecular Virology, Immunology and Medical Genetics. Dr. Schlesinger was recruited to OSU from the University of Iowa in 2002. His laboratory is focused on human mononuclear phagocyte interactions with Mycobacterium tuberculosis and more recently Francisella tularensis. Current work in the lab is focused on the role of mycobacterial cell wall lipoglycans produced in vitro and in vivo (including glycomics and lipidomics) in regulating the host inflammatory response (e.g. macrophage NODs, PPARγ), the role of core enzymes in generating mycobacterial GDP-mannose for the production of cell wall lipoglycans (bacterial knock-out and over-expression systems), pulmonary models of the innate immune response to mycobacteria (role of surfactant proteins), and identifying host susceptibility factors for tuberculosis by using functional genomics.

Books

Carlson TK, Brooks MN, Rajaram MVS, Henning LM, Meyer DA, Schlesinger LS (Marsh, Hunter, Tridandapani - eds). Pulmonary innate immunity: soluble and cellular host defense of the lung; In: Regulation of innate immune function. *: Research Signpost, STM Books, January 2010.

 

Certifications

1983 - present Diplomate: National Board of Medical Examiners
1985 - present Diplomate: American Board of Internal Medicine
1989 - present Diplomate: American Board of Internal Medicine
 

Chapters in Books

Schlesinger, LS. "Entry of M tuberculosis into cells." In Current Topics in Microbiology and Immunology. Vol. 215. 71-96. *: Springer, January 1996.

Schlesinger, LS. "Mononuclear phagocytes in tuberculosis.." In Lung Macrophages and Dendritic Cells in Health and Diseases for the series. Vol. 102. 437-480. *: Health and Diseases, January 1997.

Hornick DB, Schlesinger LS.. "Mycobacterioses (Other than TB).." In Microbiology and Microbial Infections Ninth Edition.. Vol. 3. Edited by Hausler, WJ Jr., and Sussman M,. 419-442. *: Topley & Wilson’s, January 1998.

Hornick DB, Schlesinger LS.. "Mycobacterioses (Other than TB).." In Microbiology and Microbial Infections Ninth Edition.. Edited by Hausler, WJ Jr., and Sussman M. Update 9.1-. *: Topley & Wilson’s, January 1998.

Schlesinger, LS.. "Phagocytosis and Toll-like Receptors in Tuberculosis.." In Tuberculosis 2nd Edition. Edited by William M. Rom, and Garay S.M.,. 203-214. *: Lippincott, Williams, and Wilkins, January 2004.

Matthew Fenton, Lee Riley, and Larry Schlesinger.. "Receptor-mediated recognition of Mycobacterium tuberculosis by host cells.." In Tuberculosis. Edited by Cole, Eisenach, Gicquel, McMurray, and Jacobs,. 405-426. *: American Society for Microbiology Press,, January 2004.

Larry Schlesinger, Abul Azad, Jordi Torrelles, Esteban Roberts, Isabelle Vergne, Vojo Deretic.. "Determinants of phagocytosis, phagosome biogenesis and autophagy for M. tuberculosis.." In Handbook of Tuberculosis. Immunology and Cell Biology.. Edited by Rubin, Britton, van Helden, Kaufmann. 1-22. *: Wiley VCH Publishers,, January 2008.

 

Degrees

1978 B.A., Cornell University

1982 M.D., Rutgers University

 

Edited Books

"Tuberculosis: The Microbe-Host Interface." Edited by Schlesinger, LS, DesJardin L (co-editor). *: Horizon Scientific Press, January 2004.

"Foodborne microbes: shaping the host ecosystems.." Edited by Jaykus L, Wang HH, Schlesinger (Co-editor). *: American Society for Microbiology, January 2009.

 

Editorial Activities

present The Journal of Immunology, Infection and Immunity, Immunity, The Journal of Infectious Diseases, Journal of Clinical Immunology, Spine, American Journal of Physiology: Lung Cellular and Molecular Physiology, Trends in Microbiology
present The Journal of Clinical Investigation, The Journal of Leukocyte Biology, Molecular Microbiology, JAMA, Proceedings of the National Academy of Sciences, Journal of Experimental Medicine, Journal of Biological Chemistry, Nature Genetics
present Microbial Pathogenesis, Microbiology, Nature Medicine, Nature, Science, American Journal of Respiratory and Critical Care Medicine, Journal of Investigative Dermatology, Journal of Cell Science , FEMS Microbiology Reviews
2001 - present Infections and Immunity
2007 - present Tuberculosis
2010 - present Frontiers in Microbial Immunity
 

Honors

1981 - 1982 AOA National Honor Medical Society. Littman Chapman Memorial Fund Scholarship.
1985 Department of Medicine House Officere Research Award.
1991 Florence Lindsay Trust Award for Research in Biochemistry.
1993 ICAAC Young Investigator Award.
1993 Outstanding Volunteer Service to the State of Iowa. Iowa Department of Public Health.
2003 Frank N Nelson Distinguished lecturer in Molecular Biology, Biotechnology and Medicine.
2005 America's Best Doctors.
2006 Donald V. Unverferth Department of Medicine Research Award. Department of Medicine.
2007 America's Best Doctors. U.S. News & World Report.
2007 Excellence in Teaching Award. Dept of Molecular Virology, Immunology and Medical Genetics.
2008 AAAS Fellow.
2010 Honoree, Mortar Board and Sphinx Honor Societies,.
2011 Distinguished Scholar Award. OSU Office of Research.
2011 Fellow - American Academy of Microbiology.
 

Journal Articles

Allen LA; Schlesinger LS; Kang B. "Virulent strains of Helicobacter pylori demonstrate delayed phagocytosis and stimulate homotypic phagosome fusion in macrophages.." The Journal Of Experimental Medicine. Vol. 191, no. 1. (January 2000.): 115-.

Parsa KV; Ganesan LP; Rajaram MV; Gavrilin MA; Balagopal A; Mohapatra NP; Wewers MD; Schlesinger LS; Gunn JS; Tridandapani S. "Macrophage pro-inflammatory response to Francisella novicida infection is regulated by SHIP.." Plos Pathogens. Vol. 2, no. 7. (July 2006.): e71-.

Olakanmi O; Schlesinger LS; Britigan BE. "Hereditary hemochromatosis results in decreased iron acquisition and growth by Mycobacterium tuberculosis within human macrophages.." Journal Of Leukocyte Biology. Vol. 81, no. 1. (January 2007.): 195-.

Sow FB; Florence WC; Satoskar AR; Schlesinger LS; Zwilling BS; Lafuse WP. "Expression and localization of hepcidin in macrophages: a role in host defense against tuberculosis.." Journal Of Leukocyte Biology. Vol. 82, no. 4. (October 2007.): 934-.

Mohapatra NP; Balagopal A; Soni S; Schlesinger LS; Gunn JS. "AcpA is a Francisella acid phosphatase that affects intramacrophage survival and virulence.." Infection And Immunity. Vol. 75, no. 1. (January 2007.): 390-.

Butchar JP; Rajaram MV; Ganesan LP; Parsa KV; Clay CD; Schlesinger LS; Tridandapani S. "Francisella tularensis induces IL-23 production in human monocytes.." Journal Of Immunology (Baltimore, Md.: 1950). Vol. 178, no. 7. (April 2007.): 4445-.

Wang SH; Mangino JE; Stevenson K; Yakrus MA; Cooksey R; Butler WR; Healy M; Wise MG; Schlesinger LS; Pancholi P. "Characterization of "Mycobacterium paraffinicum" associated with a pseudo-outbreak.." Journal Of Clinical Microbiology. Vol. 46, no. 5. (May 2008.): 1850-.

Parsa KV; Butchar JP; Rajaram MV; Cremer TJ; Gunn JS; Schlesinger LS; Tridandapani S. "Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNgamma response.." Molecular Immunology. Vol. 45, no. 12. (July 2008.): 3428-.

Torrelles JB; Azad AK; Henning LN; Carlson TK; Schlesinger LS. "Role of C-type lectins in mycobacterial infections.." Current Drug Targets. Vol. 9, no. 2. (February 2008.): 102-.

Torrelles JB; Azad AK; Henning LN; Carlson TK; Schlesinger LS. "Role of C-type lectins in mycobacterial infections.." Current Drug Targets. Vol. 9, no. 2. (February 2008.): 102-.

Van Zandt KE, Sow FB, Florence WC, Zwilling BS, Satoskar AR, Schlesinger LS, Lafuse WP.. "The iron export protein Ferroportin 1 is differentially expressed in mouse macrophage populations and is present in the mycobacterial-containing phagosome.." J. Leuko. Bio.. Vol. 84, (January 2008.): 689-700.

Torrelles JB, Knaup R, Kolareth A, Slepushkina T, Kaufman TM, Kang P, Hill PJ, Brennan PJ, Chatterjee D, Belisle JT, Musser JM, Schlesinger LS.. "Identification of Mycobacterium tuberculosis clinical isolates with altered phagocytosis by human macrophages due to a truncated lipoarabinomannan.." J Biol Chem.. Vol. 283, (January 2008.): 31417-31428.

Clay CD, Soni S, Gunn JS, Schlesinger LS. "Evasion of complement-mediated lysis and complement C3 deposition are dictated by Francisella tularensis LPS O-antigen." J. Immunol.. Vol. 181, (January 2008.): 5568-5578.

Henning LN, Azad AK, Parsa KVL, Crowther JE, Tridandapani S, Schlesinger LS.. "Pulmonary Surfactant Protein-A: A key regulator of Toll-Like Receptor expression and activity in human macrophages.." J. Immunol.. Vol. 180, (January 2008.): 7847-7858.

Butchar JP; Cremer TJ; Clay CD; Gavrilin MA; Wewers MD; Marsh CB; Schlesinger LS; Tridandapani S. "Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion.." Plos ONE. Vol. 3, no. 8. (January 2008.): e2924-.

Azad AK, Torrelles JB, Schlesinger LS.. "Mutation in the DC-SIGN cytoplasmic triacidic cluster motif markedly attenuates receptor activity for both phagocytosis and endocytosis of mannose-containing ligands by human myeloid cells.." J. Leuko. Bio.. Vol. 84, (January 2008.): 1594-1603.

Ernst JD; Lewinsohn DM; Behar S; Blythe M; Schlesinger LS; Kornfeld H; Sette A. "Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database.." Tuberculosis (Edinburgh, Scotland). Vol. 88, no. 4. (July 2008.): 366-.

Torrelles JB, DesJardin LE, MacNeil J, Kaufman TM, Kutzbach B, Knaup R, McCarthy TR, Gurcha SS, Besra GS, Clegg S, Schlesinger LS. "Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces cell wall lipoarabinomannan and lipomannan content and increases the rate of bacterial-induced human macrophage cell death.." Glycobiology. Vol. 19, (January 2009.): 743-755.

Carlson TK, Torrelles JB, Smith K, Horlacher T, Castelli R, Seeberger PH, Crouch E, Schlesinger LS.. "Critical role of amino acid position 343 of surfactant protein-D in the selective binding of glycolipids from Mycobacterium tuberculosis." Glycobiology. no. 19. (January 2009.): 1473-1484.

Cremer TJ, Ravneberg DH, Clay CD, Piper-Hunter MG, Marsh CB, Elton TS, Gunn JS, Amer A, Kanneganti T-D, Schlesinger LS, Butchar JP, Tridandapani S.. "Mir-155 induction by F. novicida but not the more virulent F. tularensis, results in enhanced proinflammatory cytokine response." *. no. 4. (January 2009.): e8508-.

Premanandan C, Storozuk C, Clay C, Lairmore MD, Schlesinger LS, Phipps AJ. "Complement protein C3 binding to Bacillus anthracis spores enhances phagocytosis by human macrophages.." Micro. Pathog.. Vol. 46, (January 2009.): 306-314.

Chiu H-C, Yang J, Soni S, Kulp SK, Gunn JS, Schlesinger LS, Chen C-S.. "Pharmacological exploitation of an off-target antibacterial effect of the cyclooxygenase-2 inhibitor Celecoxib against Francisella tularensis.." Antimicrob Agents and Chemotherapy. no. 53. (January 2009.): 2998-3002.

Chiu H-C, Soni S, Kulp SK, Curry H, Wang D, Gunn JS, Schlesinger LS, Chen C-S. "Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent.." J Biomed Sci.. no. 16. (January 2009.): 110-.

Day J. Friedman A, Schlesinger LS. "Modeling the immune rheostat of macrophages in the lung in response to infection.." PNAS. no. 106. (January 2009.): 11246-11251.

Chiu HC; Kulp SK; Soni S; Wang D; Gunn JS; Schlesinger LS; Chen CS. "Eradication of intracellular Salmonella enterica serovar Typhimurium with a small-molecule, host cell-directed agent.." Antimicrobial Agents And Chemotherapy. Vol. 53, no. 12. (December 2009.): 5236-5244.

Carlson TK; Torrelles JB; Smith K; Horlacher T; Castelli R; Seeberger PH; Crouch EC; Schlesinger LS. "Critical role of amino acid position 343 of surfactant protein-D in the selective binding of glycolipids from Mycobacterium tuberculosis.." Glycobiology. Vol. 19, no. 12. (December 2009.): 1473-.

Wang S-H, Pancholi P. Stevenson K, Yakrus MA, Butler WR, Schlesinger LS, Mangino JE. "Pseudo-outbreakk of "Mycobacterium paraffinicum" in a tertiary care medical center." Infections Control and Hospital Epidemiology. no. 30. (January 2009.): 848-853.

Sow FB, Alvarez GR, Gross RP, Satoskar AS, Schlesinger LS, Zwilling BS, Lafuse WP. "Role of STAT1 and C/EBPβ in the macrophage transcriptional regulation of hepcidin by mycobacterial infection and IFN-γ." Journal of Leukocyte Biology. no. 86. (January 2009.): 1247-1258.

Lustberg M. Schlesinger LS, Mangino J. "Concerns regarding "Complicated Skin and Skin-Structure Infections and Catheter-Related Bloodstream Infections: Noninferiority of Linezolid in a Phase 3 Study." Clinical Infectious Diseases - Letter to the editor. Vol. 49, (January 2009.): 313-314.

Wang S-H, Powell DA, Nagaraja HN, Morris JD, Schlesinger LS, Turner J.. "Evaluation of a modified interferon gamma release assay for the diagnosis of latent tuberculosis infection in adult and pediatric populations that enables delayed processing.." Scandinavian Journal of Infectious Diseases. Epub. (January 2010.): -.

Torrelles JB, Schlesinger LS. "Diversity in M. tuberculosis mannosylated cell wall determinants impacts adaptation to the host.." Tuberculosis. no. 90. (January 2010.): 84-93.

Rajaram MVS, Morris JD, Brooks MN, Torrelles JB, Azad AK, Schlesinger LS.. "Mycobacterium tuberculosis activates human macrophage PPARγ linking mannose receptor recognition to regulation of immune responses.." J Immunol. no. 185. (January 2010.): 929-942.

Day J; Schlesinger LS; Friedman A. "Tuberculosis research: going forward with a powerful "translational systems biology" approach.." Tuberculosis (Edinburgh, Scotland). Vol. 90, no. 1. (January 2010.): 7-.

Clay CD, Gunn JS, Schlesinger LS. "Antibody-independent classical complement pathway activation by wildtype and LPS O-antigen mutant Francisella tularensis strains.." Mol Immun. no. 47. (January 2010.): 2245-.

Mohapatra NP, Soni S, Rajaram M, Dang PMC, Reilly TJ, El-Benna J, Schlesinger LS, Gunn JS.. "Francisella acid phosphatases inactivate the NADPH oxidase in human phagocytes by dephosphorylation of p47phox and p40phox." J Immunology Epub. (January 2010.): -.

Dwivedi V, Manickam C, Patterson R, Dodson K, Murtaugh M, Torrelles JB, Schlesinger LS, Renukaradhya GJ.. "Cross-protective immunity to porcine reproductive and respiratory syndrome virus by intranasal delivery of a live virus vaccine with a potent adjuvant.." Vaccine - Epub. (January 2011.): -.

Day J, Friedman A, Schlesinger LS. "Modeling the host response to inhalation anthrax." J. Theoretical Bio. no. 276. (January 2011.): 199-208.

Dai S, Mohapatra NP, Schlesinger LS, Gunn JS. "Regulation of Francisella virulence." Frontiers in Cellular and Infection Microbiology. no. 1. (January 2011.): 1-10.

Sow FB, Nandakumar S, Velu V, Kellar KL, Schlesinger LS, Amara RR, Lafuse WP, Shinnick TM, Sable SB. "Mycobacterium tuberculosis components stimulate production of the antimicrobial peptide hepcidin.." Tuberculosis. (January 2011.): -.

Brooks MN, Rajaram MVS, Azad AK, Amer A, Valdivia-Arenas MA, Park J-H, Nunez G, Schlesinger LS.. "NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages.." Cell Microbiol.. no. 13. (January 2011.): 402-418.

 

Reference Works

July 2008 Lafuse WP, Sow F, Alvarez GR, Schlesinger LS."Regulation of hepcidin expression and phagosome trafficking in mouse macrophages" Baltimore.
September 2008 Clay CD, Soni S, Gunn JS, Schlesinger LS."LPS O-antigen dictates whether complement activation by Francisella tularensis results in microbial lysis by regulating C3 deposition." Madison.
October 2009 Keiser TL, Azad AK, Guirado E, Torrelles JB, Zimmerer J, Schlesinger LS."Altering the expression of Mycobacterium tuberculosis polprenol monophosphomannose synthase that generates key mannose donors for cell envelope mannose-containing lipoglycans important in bacterial virulence." , W. Lafayette.
October 2009 Mishra M, Azad AK, Schlesinger LS, Wozniak DJ."Role of microbial exopolysaccharides in the battle against the host immune response: Stubborn P. aeruginosa biofilms in cystic fibrosis." W. Lafayette.
January 2010 Torrelles JB, Sieling PA, Arcos, J, Knaup R, Bartling C, Rajaram MVS, Modlin RL, Schlesinger, LS.."Structural differences in lipomannans from pathogenic and non-pathogenic mycobacteria and their impact on CD1b-restricted T cell proliferation." Cambridge.
January 2010 Wang S-H, Perkins L, Beane K, Pan J, Ervin M, Betz Bret B, Morris J, Schlesinger LS, and Powell DA.."Comparison of Tuberculin Skin Test to QuantiFERON-TB® and T-SPOT®.TB assay in Children Diagnosed with Latent Tuberculosis Infection." Vancouver.
January 2010 Guirado E, Azad AK, Keiser TL, Schlesinger LS."Cloning and characterization of genes involved in the biosynthetic pathway for cell envelope mannose-containing lipoglycans in Mycobacterium tuberculosis." St. Louis.
January 2010 Clay CD, Gunn JS, Schlesinger LS.."Antibody-independent classical complement pathway activation by wildtype and LPS O-antigen mutant Francisella tularensis strains" New York.
January 2010 Keiser TL, Guirado E, Azad AK, Bonacci R, Schlesinger LS.."Transcriptional profiling of putative genes in the mannose donor biosynthetic pathway in Mycobacterium tuberculosis and Mycobacterium bovis BCG." St. Louis.
January 2011 Rajaram MVS, Morris JD, Brooks MN, Carlson TK, Torrelles JB, Schlesinger LS."M. tuberculosis lipomannan blocks TNF- biosynthesis in human macrophages by regulation of MAP kinase-activated protein kinase 2 (MK2) and miR125b." .
January 2011 Julian MW, Shao G, Huang Q, Bhatt N, Cosmar D, Phillips G, Schlesinger L, Culver D,Baughman R, Wood K and Crouser ED."Nicotine Treatment for Sarcoidosis: Pilot Study Results." Denver.
January 2011 Azad AK, Papp A, Ni B, Zaret A, Hesse E, Knoell D, Sadee W, Schlesinger LS."Identification of candidate functional polymorphisms in the human pulmonary surfactant protein A2 gene based on allelic expression imbalance." .
January 2011 Arcos J, Sasindran S, Fujiwara N, Turner J, Schlesinger LS, and Jordi B. Torrelles JB."Lung surfactant hydrolases alter the infection outcome of Mycobacterium tuberculosis in human macrophages." .
January 2011 Tracy L. Keiser TL, Azad AK, Guirado E, Bonacci R, Schlesinger LS.."Transcriptional profiling of putative genes in the mannose donor biosynthetic pathway in Mycobacterium tuberculosis and Mycobacterium bovis BCG strains." .
January 2011 Torrelles JB, Sieling PA, Arcos J, Knaup R, Bartling C, Rajaram MVS, Modlin RL, Schlesinger LS."Structural differences in lipomannans from pathogenic and non-pathogenic mycobacteria and their impact on CD1b-restricted T cell proliferation." .
January 2011 Brooks MN, Rajaram MVS, Azad AK, Amer AO, Valdivia-Arenas MA, Park J-H, Núñez G, Schlesinger LS.."NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages." .
January 2011 Guirado E, Azad AK, Arcos J, Keiser TL, Yang L, Torrelles JB, Schlesinger LS.."Characterization of a Mycobacterium tuberculosis operon that regulates mannosylation of the mycobacterial cell wall." .

Presentations

"Annual Program Meeting of the Tuberculosis Research Unit, Case Western Reserve University." Cleveland, OH. (October 2005)

"Insight into M. tuberculosis adaptation to macrophages in the human respiratory system." Presented at Institute for Environmental Medicine, University of Pennsylvania, Philadelphia, PA. (May 2009)

"“Innate immunity: regulation of lung innate defense to airborne pathogens.� CBRNIAC-sponsored technology forum on emerging CBRN defense R&D requirements." Presented at Battelle Eastern Science and Technology Center, Aberdeen, MD. (September 2009)

"Innate immunity: regulation of lung innate defense to airborne pathogens." Presented at CBRNIAC-sponsored technology forum on emerging CBRN defense R&D requirements, Battelle Eastern Science and Technology Center, Aberdeen, MD. (September 2009)

""Interplay of M. tuberculosis and macrophages in the human respiratory system."." Presented at UT School of Public Health, Brownsville campus,, Brownsville,, TX. (November 2009)

"Interplay of M. tuberculosis and macrophages in the human respiratory system UT School of Public Health, Brownsville campus." Brownsville, TX. (November 2009)

"“Altered macrophage interactions within the lung alveolus: Impact on tuberculosis infection.�." Presented at the Optimization of Inhaled Tuberculosis Therapies and Implications for Host-Pathogen Interactions, New Delhi, India. (November 2009)

"Insight into M. tuberculosis adaptation to the human respiratory system." Presented at Immunology Seminar Series. Case Western Reserve University, Cleveland, OH. (March 2009)

"“Interplay of M. tuberculosis and macrophages in the human respiratory system.�." Presented at Public Health Research Institute Center at UMDNJ New Jersey Medical School, Newark, NJ. (October 2009)

""Annual Program Meeting of the Tuberculosis Research Unit"." Presented at Case Western Reserve University, Cleveland, OH. (October 2009)

"Interplay of M. tuberculosis and macrophages in the human respiratory system." Presented at Public Health Research Institute Center at UMDNJ New Jersey Medical School, Newark, NJ. (October 2009)

""Host and bacterial targets mediating immune suppression in pneumonic tularemia"." Presented at GLRCE Annual Meeting, Chicago, IL. (December 2009)

"Mycobacterium tuberculosis activates PPAR?, a key regulator of human macrophage immune responses, through ligation of the mannose receptor.." Presented at the 45th US-Japan Cooperative Medical Sciences Program, Tuberculosis and Leprosy Panel Conference, workshop and New England TB symposium, Broad Institute, Cambridge, MA. (July 2010)

"The nature of infectious disease: little bugs, big problems. The supreme court of Ohio judicial college: introduction to public health & science." Presented at Cherry Valley Lodge, . (August 2010)

"Adaptive interplay of M. tuberculosis and macrophages in the human respiratory system.." Presented at Instituto De Investigaciones Biomedicas. Universidad Nacional Autonoma de Mexico., Nexico City, Mexico. (August 2010)

"Adaptive interplay of M. tuberculosis and macrophages in the human respiratory system.." Presented at the IV Simposio fronteras del conocimiento en Tuberculosis y otras Micobacteriosis. V Reunion SLAMTB., Zacatecas, Mexcio. (August 2010)

"Interplay of M. tuberculosis and macrophages in the human respiratory system.." Presented at the 91st Annual Meeting of the Conference of Research Workers in Animal Diseases (CRWAD)., Chicago, IL. (December 2010)

"“Interplay of Mycobacterium tuberculosis and macrophages in the human respiratory system.�." Presented at the 1st Annual Infection and Immunity Symposium, at Northwestern University, Chicago, IL. (March 2011)

"“A link between complement receptor 3-mediated uptake of Francisella tularensis and immune suppression in human macrophages,." Presented at the Seventh National RCE Meeting, Denver, CO. (April 2011)