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Jonathan Honegger, PhD


700 Childrens Dr
Columbus, OH 43205

Phone: (614) 722-4450

Email: honegger.6@osu.edu

 

Current OSU Appointment

Assistant Professor-Clinical, Pediatrics

 

Academic Advising

2012 - present Ryan Cox, Nationwide Children’s Hospital.
2013 - present , Nationwide Children’s Hospital.
2014 Samantha Ohmer, The Ohio State University. Graduated 0.
 

Licenses

2004 - 2014 Certified: American Board of Pediatrics
2004 - 2014 Certified: American Board of Internal Medicine
2009 - 2016 Certified: American Board of Pediatrics
 

Chapters in Books

Honegger JR, Brady MT. "Viral Respiratory Infections." In Rudolph's Pediatrics. 22nd ed. Edited by Colin Rudolph, Abraham Rudolph, George Lister, Lewis First, Anne Gershon. -. New York, NY, US|USA: McGraw-Hill Publishers, January 2011.

 

Conferences

Honegger J, Potter C, Cawthon D, Walker C,. "Intrahepatc cellular immunity in vertically acquired hepatitis C virus infection." St. Jude’s/Pediatric Infectious Diseases Society Meeting. (January 0). .

Bowen DG, Cawthon AG, Honegger JR, Rutkiewicz J, Murthy KK, Walker CM. "High-level HCV replication during acute infection occurring in the absence of reversion of previously acquired cytotoxic T lymphocyte escape mutations." In Hepatology. (October 2006). 296A-296A.

Honegger JR, Prasad MR, Colombo D, Bowen DG, Walker CM. "HCV-specific T-cell responses during acute Hepatitis C Virus infection in pregnancy." In Retrovirology. (April 2008). O8-.

Honegger JR, Prasad MR, Kohout JA, Walker CM. "Influence of Pregnancy on Hepatitis C Virus Evolution." 17th International Meeting on Hepatitis C and Related Viruses Program and Abstract Book. (September 2010). P-205.

Honegger JR, Kohout JA, Kim S, et al.. "Reversion of cytotoxic T-cell escape mutation during pregnancy permits vertical transmission of most fit hepatitis C variant." 18th International Symposium on Hepatitis C Virus and Related Viruses Abstract Book. (September 2011). P2.20-.

Omikunle A, Walker CM, Honegger JR. "Hepatitis C virus specific T-cell responses in vertically exposed infants." Pediatric Academic Societies Abstract2View. (May 2011). 2941.449-.

Prasad MR, Honegger JR, Markham KB; Walker CM. "Clinical risk factors associated with mother-to-child transmission (MTCT) of hepatitis C virus (HCV)." In American Journal of Obstetrics and Gynecology. (January 2012). S270-S270.

 

Degrees

1995 B.S., Purdue University

2000 M.D., Indiana University

 

Editorial Activities

2012 - present PLOS Pathogens
2013 - present PLOS One
2013 - present Pediatric Infectious Diseases Journal
2014 - present American Journal of Perinatology
2015 - present Frontiers in Pediatrics
 

Honors

2009 - present IDSA Program Committee Career Award. Infectious Diseases Society of America.
 

Journal Articles

Dotson JL, Crandall W, Mousa H, Honegger JR, Denson L, Samson C, Cunningham D, Balint J, Deinhart M, Jaggi P, Carvalho R. "Presentation and Outcome of Histoplasmosis in Pediatric Inflammatory Bowel Disease Patients Treated with Antitumor Necrosis Factor alpha Therapy: A Case Series." Inflammatory Bowel Diseases. Vol. 17, no. 1. (January 2011.): 56-61.

Dotson,Jennifer,L; Crandall,Wallace; Mousa,Hayat; Honegger,Jonathan,R; Denson,Lee; Samson,Charles; Cunningham,Dennis; Balint,Jane; Dienhart,Molly; Jaggi,Preeti; Carvalho,Ryan. "Presentation and Outcome of Histoplasmosis in Pediatric Inflammatory Bowel Disease Patients Treated with Antitumor Necrosis Factor alpha Therapy: A Case Series." INFLAMMATORY BOWEL DISEASES. Vol. 17, no. 1. (January 2011.): 56-61.

Prasad,Mona; Honegger,Jonathan; Markham,Kara,B; Walker,Christopher. "Clinical risk factors associated with mother-to-child transmission (MTCT) of hepatitis C virus (HCV)." AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. Vol. 206, no. 1. (January 2012.): S270-S270.

Prasad,Mona; Honegger,Jonathan; Markham,Kara,B; Walker,Christopher. "Clinical risk factors associated with mother-to-child transmission (MTCT) of hepatitis C virus (HCV)." AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. Vol. 206, no. 1. (January 2012.): S270-S270.

Prasad MR, Honegger JR. "Hepatitis C Virus in Pregnancy." American Journal of Perinatology. Vol. 30, no. 2. (February 2013.): 149-159.

Honegger JR, Kim S, Price AA, Kohout JA, McKnight KL, Prasad MR, Lemon SM, Grakoui A, Walker CM. "Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses." Nature Medicine. Vol. 19, no. 11. (November 2013.): 1529-1533.

Honegger JR, Zhou Y, Walker CM. "Will there be a vaccine to prevent HCV infection?." Seminars in Liver Diseases. Vol. 34, no. 1. (February 2014.): 79-88.

Price AA, Grakoui A, Honegger JR. "Hepatitis C virus adaptions to altered CD8+ T-cell immunity during pregnancy." Future Virology. Vol. 9, no. 4. (April 2014.): 333-336.

Barson WJ, Honegger JR, Texter K. "Acute myopericarditis associated with cat scratch disease in an adolescent." Pediatric Infectious Disease Journal. Vol. 33, no. 9. (September 2014.): 982-984.

Honegger JR, Zhou Y, Walker CM. "Will there be a vaccine to prevent HCV infection?." Seminars in Liver Disease. -.

 

Presentations

"Intrahepatic Cellular Immunity in Vertically Acquired Hepatitis C Virus Infection." Presented at St. Jude's/PIDS Pediatric Infectious Diseases Conference, Memphis, TN, US|USA. (February 2007)

"T-cell Immunity to Hepatitis C Virus Infection During Pregnancy." Presented at Research Institute Annual Retreat, Columbus, OH, US|USA. (March 2008)

"Maternal and Infant T-cell Immunity to the Hepatitis C Virus." Presented at Clinical Research Seminar, Columbus, OH, US|USA. (June 2008)

"Maternal Immunity to the Hepatitis C Virus." Presented at Immunology Journal Club/Work in Progress, Columbus, OH, US|USA. (September 2008)

"Postpartum Surge in T-cell Immunity to the Hepatitis C Virus." Presented at NIH (NICHD) Child Health Research Centers Annual Retreat, Seattle. (September 2009)

"Postpartum Surge in T-cell Immunity to the Hepatitis C Virus." Presented at Infectious Diseases Society of America Annual Meeting, Philadelphia, PA, US|USA. (October 2009)

"Preventing Mother to Child Transmission of the Hepatitis C Virus." Presented at BOSS Seminar, Columbus. (May 2009)

"Hepatitis C in Pregnancy and Vertical Transmission." Presented at Nationwide Children's Hospital Gastroenterology Morning Conference, Columbus, OH, US|USA. (July 2011)

"Hepatitis C Update." Presented at Association of Ohio Health Commissioners Fall Conference, Dublin. (September 2012)

"T-cell immunity to Hepatitis C in mothers and infants - learning from the virus." Presented at ID Consortium Work in Progress, Nationwide Children's Hospital, Columbus, OH, US|USA. (November 2012)

"Broadened Virus-Specific T-cell Responses are Associated with Postpartum Declines in Hepatitis C Viremia." Presented at Infectious Diseases Society of America Annual Meeting, San Diego, CA, US|USA. (October 2012)

"Hepatitis C Update." Presented at Nationwide Children's Hospital Gastroenterology Morning Conference, Columbus, OH, US|USA. (January 2013)

"Hepatitis C in Pregnancy: a Unique Setting to Understand Restoration of Immunity." Presented at Hepatitis C Cooperative Research Centers Immunology Workshop, Bethesda, MD, US|USA. (July 2013)

"Hepatitis C in Pregnancy--How Altered Maternal Immunity can Influence Replicative Capacity of Vertically Transmitted Viruses." Presented at Emory Vaccine Center Special Seminar, Atlanta, GA, US|USA. (February 2013)

"Hepatitis C in Pregnancy—How Altered Maternal Immunity can Influence Replicative Capacity of Vertically Transmitted Viruses." Presented at Hepatitis C Seminar Series, New York, NY, US|USA. (November 2013)

"Cellular immunity to the hepatitis C virus during and after pregnancy." Presented at Center for Aids Research Seminar Series, Cleveland, OH, US|USA. (February 2014)

"The Immunology Behind Perinatal Hepatitis C Transmission." Presented at Pediatric Academic Societies Annual Meeting, Vancouver, BC, CA|CAN. (May 2014)

"Immunity Before and After Perinatal Hepatitis C Infection." Presented at ID Consortium Work in Progress, Nationwide Children's Hospital, Columbus, OH, US|USA. (August 2014)

 

Professional Activities

2015 - present Antimicrobial Drugs Advisory Committee. Food and Drug Administration. Silver Springs, MD.
2009 Pediatric infectious diseases teaching and consultation services. Rumah Sakit Umum Bethesda.
2011 Pediatric infectious diseases teaching and consultation services. Rumah Sakit Umum Bethesda.
2013 - 2015 Antiviral Drugs Advisory Committe. Food and Drug Administration. Silver Spring, MD.