Ohio State Navbar


Joanne Trgovcich, PhD

Staff photo

473 W 12th Ave
Columbus, OH 43210

Phone: (614) 688-3353

Email: trgovcich.1@osu.edu


Current OSU Appointment

Adjunct Assistant Professor, Critical Care, Trauma & Burn


Advising Narrative

(1) K.M. received a 2nd Place Prize in the Biological Sciences Competition at the 2004 Ohio State University Denman Undergraduate Research Forum; (2) K.M. also received an honors in research degree; and (3) an Award of Merit from the School of Allied Health Sciences. K.M is now at The OSU Medical School. (1) In 2004, J.C. received the College of Biological Sciences Research Award ($500 towards tuition); (2) In 2005, J.C. placed among the top 3 students in her division in the College of Biological Sciences Undergraduate Research Colloquim; (3) In 2005, J.C. was awarded the 2005 Glenn-Stokes Summer Research Internship at Ohio State University (sponsored by the Ohio Science and Engineering Alliance). (1) the Dean’s Undergraduate Research Fund Award in both May and Autumn of 2007, and (2) the Colleges of the Arts and Sciences Undergraduate Research Scholarship in spring, 2006. Awarded the 2006 Glenn-Stokes Summer Research Internship at Ohio State University (sponsored by the Ohio Science and Engineering Alliance). Niti Shah received the Dean’s Undergraduate Research Fund Award in the College of Biological Sciences award in Winter Quarter, 2009.


1989 B.S., Purdue University

1996 Ph.D., University of North Carolina


Editorial Activities

2008 - present Microbes and Infection


1991 Honorable Mention NSF predoctoral award. NSF.
1993 - 1995 United States Army Research Office Predoctoral Training Grant. "Graduate training in the Design of Genetically Engineered Viral Vaccines.". United States Army Research Office.
1997 - 1999 Recipient. Cancer Biology Training Grant Postdoctoral Fellowship.
2003 Recipient of GlaxoSmithKline Elion Research Award. GlaxoSmithKline and the International Herpes Management Forum.

Journal Articles

Davies, C, J; Trgovcich, J; Hutchison, C A 3rd. "Homologue of TFIIS in yeast.." Nature. Vol. 345, no. 6273. (January 1990.): 298-.

Trgovcich, J; Aronson, J, F; Johnston, R E. "Fatal Sindbis virus infection of neonatal mice in the absence of encephalitis.." Virology. Vol. 224, no. 1. (January 1996.): 73-83.

Trgovcich, J; Ryman, K; Extrom, P; Eldridge, J, C; Aronson, J, F; Johnston, R E. "Sindbis virus infection of neonatal mice results in a severe stress response.." Virology. Vol. 227, no. 1. (January 1997.): 234-8.

Polic, B; Hengel, H; Krmpotic, A; Trgovcich, J; Pavic, I; Luccaronin, P; Jonjic, S; Koszinowski, U H. "Hierarchical and redundant lymphocyte subset control precludes cytomegalovirus replication during latent infection.." The Journal of experimental medicine. Vol. 188, no. 6. (January 1998.): 1047-54.

Trgovcich, J; Aronson, J, F; Eldridge, J, C; Johnston, R E. "TNFalpha, interferon, and stress response induction as a function of age-related susceptibility to fatal Sindbis virus infection of mice.." Virology. Vol. 263, no. 2. (January 1999.): 339-48.

Trgovcich, J; Stimac, D; Polic, B; Krmpotic, A; Pernjak-Pugel, E; Tomac, J; Hasan, M; Wraber, B; Jonjic, S. "Immune responses and cytokine induction in the development of severe hepatitis during acute infections with murine cytomegalovirus.." Archives of virology. Vol. 145, no. 12. (January 2000.): 2601-18.

Charles, P, C; Trgovcich, J; Davis, N, L; Johnston, R E. "Immunopathogenesis and immune modulation of Venezuelan equine encephalitis virus-induced disease in the mouse.." Virology. Vol. 284, no. 2. (January 2001.): 190-202.

Trgovcich, Joanne; Johnson, David; Roizman, Bernard. "Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1.." Journal of virology. Vol. 76, no. 14. (January 2002.): 6974-86.

Nieuwenhuis, Edward E, S; Neurath, Markus, F; Corazza, Nadia; Iijima, Hideki; Trgovcich, Joanne; Wirtz, Stefan; Glickman, Jonathan; Bailey, Dan; Yoshida, Masaru; Galle, Peter, R; Kronenberg, Mitchell; Birkenbach, Mark; Blumberg, Richard S. "Disruption of T helper 2-immune responses in Epstein-Barr virus-induced gene 3-deficient mice.." Proceedings of the National Academy of Sciences of the United States of America. Vol. 99, no. 26. (January 2002.): 16951-6.

Cook, Charles, H; Trgovcich, Joanne; Zimmerman, Peter, D; Zhang, Yingxue; Sedmak, Daniel D. "Lipopolysaccharide, tumor necrosis factor alpha, or interleukin-1beta triggers reactivation of latent cytomegalovirus in immunocompetent mice.." Journal of virology. Vol. 80, no. 18. (January 2006.): 9151-8.

Trgovcich, Joanne; Cebulla, Colleen; Zimmerman, Pete; Sedmak, Daniel D. "Human cytomegalovirus protein pp71 disrupts major histocompatibility complex class I cell surface expression.." Journal of virology. Vol. 80, no. 2. (January 2006.): 951-63.

Zhang, Guojuan; Raghavan, Bindu; Kotur, Mark; Cheatham, Jacquelyn; Sedmak, Daniel; Cook, Charles; Waldman, James; Trgovcich, Joanne. "Antisense transcription in the human cytomegalovirus transcriptome.." Journal of virology. Vol. 81, no. 20. (January 2007.): 11267-.

Bickerstaff, Alice, A; Zimmerman, Peter, D; Wing, Bret, A; Taylor, Frederick; Trgovcich, Joanne; Cook, Charles H. "A flow cytometry-based method for detecting antibody responses to murine cytomegalovirus infection.." Journal of virological methods. Vol. 142, no. 1-2. (January 2007.): 50-.

McNally BA; Trgovcich J; Maul GG; Liu Y; Zheng P. "A role for cytoplasmic PML in cellular resistance to viral infection.." Plos ONE. Vol. 3, no. 5. (January 2008.): e2277-.

Machesky NJ; Zhang G; Raghavan B; Zimmerman P; Kelly SL; Merrill AH Jr; Waldman WJ; Van Brocklyn JR; Trgovcich J. "Human cytomegalovirus regulates bioactive sphingolipids.." The Journal Of Biological Chemistry. Vol. 283, no. 38. (September 2008.): 26148-.


Professional Activities

2003 High School Student - Drew Carter. Columbus City Schools. Columbus, OH.
2004 High School Student - Rachel Mozenta. The Columbus Academy. Columbus, OH.
2005 High School Student - Erin Wolf. The Columbus Academy. Columbus, OH.
2006 High School Student - Erin Wolf. The Columbus Academy. Columbus, OH.
2007 High School Student - Elizabeth Nick. The Ohio State University College of Medicine. Columbus, OH.