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Jian Zhang, PhD

460 W 12th Ave
Columbus, OH 43210

Phone: (614) 292-9447

Email: zhang.3570@osu.edu


Current OSU Appointments

Associate Professor, SBS-Microbial Infectn/Immunity

Associate Professor, Immunology & Rheumatology


Journal Articles

Zhang,J. "Ubiquitin ligases in T cell activation and autoimmunity." CLINICAL IMMUNOLOGY. Vol. 111, no. 3. (June 2004.): 234-240.

Qiao,Guilin; Lei,Minxiang; Li,Zhenping; Sun,Yonglian; Minto,Andrew; Fu,Yang-Xin; Ying,Haiyan; Quigg,Richard,J; Zhang,Jian. "Negative regulation of CD40-mediated B cell responses by E3 ubiquitin ligase casitas-B-lineage lymphoma protein-B." JOURNAL OF IMMUNOLOGY. Vol. 179, no. 7. (October 2007.): 4473-4479.

Guo,Hui; Qiao,Guilin; Ying,Haiyan; Li,Zhenping; Zhao,Yixia; Liang,Yanran; Yang,Lifen; Lipkowitz,Stanley; Penninger,Josef,M; Langdon,Wallace,Y; Zhang,Jian. "E3 Ubiquitin Ligase Cbl-b Regulates Pten via Nedd4 in T Cells Independently of Its Ubiquitin Ligase Activity." CELL REPORTS. Vol. 1, no. 5. (May 2012.): 472-482.

Qiao,Guilin; Zhao,Yixia; Li,Zhenping; Tang,Peter,Q; Langdon,Wallace,Y; Yang,Tianlan; Zhang,Jian. "T Cell Activation Threshold Regulated by E3 Ubiquitin Ligase Cbl-b Determines Fate of Inducible Regulatory T Cells." JOURNAL OF IMMUNOLOGY. Vol. 191, no. 2. (July 2013.): 632-639.

Qiao,Guilin; Ying,Haiyan; Zhao,Yixia; Liang,Yanran; Guo,Hui; Shen,Huifeng; Li,Zhenping; Solway,Julian; Tao,Enxiang; Chiang,Y,Jeffrey; Lipkowitz,Stanley; Penninger,Josef,M; Langdon,Wallace,Y; Zhang,Jian. "E3 Ubiquitin Ligase Cbl-b Suppresses Proallergic T Cell Development and Allergic Airway Inflammation." CELL REPORTS. Vol. 6, no. 4. (February 2014.): 709-723.

Liu,Qingjun; Zhou,Hong; Langdon,Wallace,Y; Zhang,Jian. "E3 ubiquitin ligase Cbl-b in innate and adaptive immunity." CELL CYCLE. Vol. 13, no. 12. (June 2014.): 1875-1884.

Veselits,Margaret; Tanaka,Azusa; Lipkowitz,Stanley; O'Neill,Shannon; Sciammas,Roger; Finnegan,Alison; Zhang,Jian; Clark,Marcus,R. "Recruitment of Cbl-b to B Cell Antigen Receptor Couples Antigen Recognition to Toll-Like Receptor 9 Activation in Late Endosomes." PLOS ONE. Vol. 9, no. 3. (March 2014.): e89792-.

Zhao,Yixia; Guo,Hui; Qiao,Guilin; Zucker,Mark; Langdon,Wallace,Y; Zhang,Jian. "E3 Ubiquitin Ligase Cbl-b Regulates Thymic-Derived CD4(+)CD25(+) Regulatory T Cell Development by Targeting Foxp3 for Ubiquitination." JOURNAL OF IMMUNOLOGY. Vol. 194, no. 4. (February 2015.): 1639-1645.

Xiao,Yun; Qiao,Guilin; Tang,Juan; Tang,Rong; Guo,Hui; Warwar,Samantha; Langdon,Wallace,Y; Tao,Lijian; Zhang,Jian. "Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation." JOURNAL OF IMMUNOLOGY. Vol. 195, no. 9. (November 2015.): 4218-4227.