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Jeffrey Lakritz, DVM, PhD


Staff photo

601 Vernon Tharp St
Columbus, OH 43210

Phone: (614) 292-6661

Email: lakritz.1@osu.edu

 

Current OSU Appointment

Professor, Veterinary Clinical Sciences

 

Clinical Interest

Internal medicine of Large Animals

Advising Narrative

Mary Kopechek, Undergraduate honors research project. Expression of differentiation markers on bovine alveolar macrophages in relation to bovine respiratory disease. Richard H. Kellogg Scholarship, William C Hauk Scholarship. 2006-2007.



Kathleen O’Conner, Undergraduate research project. Cloning and expression of equine MMP 9. Funded by American Live Stock Insurance company grant to Steven M. Reed. Currently VM IV The Ohio State University.



Melissa Long, Undergraduate student, laboratory externship. May 2008 – June 2009. Bovine alveolar macropahge CD163 mRNA; GenBank accession # GQ184570.



Jackie Delaccio, Undergraduate work-study student externship. Serum and synovial fluid concentrations of erythromycin in horses receiving 1 or 2 grams IV by intravenous regional infusion. Funded by UTenn grant to Gal Kelmer DVM (faculty, Koret School of Veterinary Medicine, Israel). M. haemolamae transplacental transmission in alpacas; performed most of the laboratory work (PCR based detection, IFA analysis of M haemolamae specific serum and colostral antibodies). Funded by Morris Animal Foundation grant to J Lakritz. Supervised by Dr. Antoinette E Marsh.



Nicholas Werle, Veterinary student; work study internship. Bovine neutrophil granule haptoglobin is only found in complex with MMP 9. Spring 2011-2012. HPLC of serum florfenicol and alpacas and Llamas. Publication of results in Research in Veterinary Science 2013; Partially funded by gift from the Pennsylvania Llama and Alpaca Association;



Amelia Nyhart, Pre-Veterinary Animal Sciences major. Laboratory assistant in training, summer 2011-2012. Analyzed concentration versus time data of serum florfenicol concentrations by non-compartmental statistical analysis (WinNonlin version 5.2 (Admitted to The Ohio State University College of Veterinary Medicine Class of 2016

Clinical Interest

Pharmacology of Large Animals

Biographical

I am a graduate Veterinarian (1987) with post-doctoral training in large animal medicine and surgery (Academic internship and residency) that pursued advanced research training in an NIH funded basic research laboratory. I received my doctoral degree in 1997, and obtained my first academic appointment in 1998. I have been in academic clinical medicine for my entire career (1998-2014).



My clinical appointment is currently 25%, with a 75% research appointment. The research I am pursuing involves lung inflammation, bovine respiratory disease and pharmacologic modulation of inflammation. My laboratory has studied biomarkers of neutrophil activation and developed assays to monitor neutrophil biomarkers in cattle with respiratory and other inflammation.

Academic Advising

2011 - present Dr. Amanda The Ohio State University. Effects of Morphine-Lidocaine-Ketamine CRI on post-operative pain in calves undergoing umbilical hernia repair
2012 - present Sarah Depenbrock The Ohio State University. Synovial concentrations of ampicillin-sulbactam after intravenous regional perfusion of dairy cattle
2013 - present Caroline Lodge-Stark The Ohio State University.
1998 - 2000 Antonio Alvarez University of Missouri. Graduated 2000. Role of gamma/delta-T cells in Mycobacterial Infection and inflammation
1999 - 2002 Hosam Al-Tamimi University of Missouri. Effect of nitric oxide donors on thermoregulation and performance of rats and cattle experiencing fescue toxicosis during heat stress
2000 - 2002 Jefrey Chakwenya University of Missouri. Potentiated sulfonamides in Veterinary medicine
2002 - 2004 Gagan Gupta University of Missouri. Expression of recombinant S. neurona SAG1 gene in baculovirus expression system: characterization and functional evaluation
2002 - 2004 Aliya Wilson University of Missouri. Stage specific detection and characterization of enolase by Sarcocystis neurona.
2004 Zhihong Zhang The Ohio State University. Pharmacokinetics, in vitro absorption and metabolism of perillyl alcohol, a chemopreventative and chemotherapeutic agent
2003 - 2005 Claire Whitehead The Ohio State University. Effect of supplemental Vitamin D on serum 25-OH Vitamin D in alpaca dams and their crias
2000 - 2006 Masie Dawes University of Missouri. Effect of colostral lactoferrin on neonatal immune function.
2003 - 2006 Sylvan Nichols The Ohio State University. Graduated 2006. Theloscopic methods of surgical teat injury in cows: experimental wound model to assess healing of wounds
2004 - 2006 Daniel Linden The Ohio State University. Use of organic Zinc in diets of South American camelids, llamas (Lama glama), alpacas (Lama pacos)
2006 Hyunjoong Cho The Ohio State University. Simultaneous determination of flow stress and friction using finite element analysis
2005 - 2007 Christina Robinson The Ohio State University. Graduated 2007. Matrix metalloproteinases in the equine central nervous system : use of computed tomography of the equine skull and brain
2005 - 2007 Christopher Premanandan The Ohio State University. Graduated 2007. Interaction of Bacillus Anthracis with macrophages
2006 - 2007 MaryBeth Kopechek The Ohio State University. Graduated 2008.
2005 - 2008 Anita Varga The Ohio State University. Cardiac Troponin and its use in clinical medicine of cattle
2005 - 2008 Christian Gerspach The Ohio State University. Graduated 2008. Characterization of the expression of the haptoglobin receptor CD163 in bovine alveolar macrophages and the receptor phenotype in CD163+ cells.
2006 - 2008 Kari Newman The Ohio State University. Graduated 2008. Factors affecting lactoferrin concentration at drying off and infection status at calving in dairy cows on an intermittant milking schedule prior to drying off
2008 Jongjoo Kim The Ohio State University. Graduated 2008.
2009 Shuo (Dennis) The Ohio State University. Graduated 2009. Peroxisome proliferator activated receptor gamma (PPARg)-independent anti tumor effect of thiazolidinediones.
2010 Veerasamy Sejian The Ohio State University.
2010 Jesse Martin The Ohio State University. Graduated 2010. Magnetic field dependent charge transport studies in organic semiconducting materials
2008 - 2011 Charles (Austin) The Ohio State University. Graduated 2011. LPS induced inflammation in calves. Serum Hp-MMP 9 complex as an acute phase response protein complex of neutrophils
2011 Christopher J The Ohio State University. Graduated 2011. The role of micro-RNA-181a in acute leukemia: biological, clinical and therapeutic interventions
2010 - 2012 Rebecca Pentecost The Ohio State University. Graduated 2012. Vertical transmission of Mycoplasma Haemolamae in alpaca cria
2011 - 2012 Kazuyuki Suzuki The Ohio State University.
2011 - 2012 Carrie Belles The Ohio State University. Graduated 2012.
2011 - 2013 Brandon Forshey The Ohio State University. Graduated 2013. Embryo production by superovulation and dual siring in alpacas.
2012 - 2013 David Pontius The Ohio State University. Graduated 2013.
 

Certifications

1987 - present Doctor of Veterinary Medicine: California Veterinary Medical Board
1992 - present Doctor of Veterinary Medicine: Florida Board of Veterinary Medicine
1997 - present Diplomate American College of Veterinary Internal Medicine: American College of Veterinary Internal Medicine
1999 - present Doctor of Veterinary Medicine: Missouri Veterinary Medical Board
2004 - present Doctor of Veterinary Medicine: Ohio Veterinary Medical Licensing Board
 

Chapters in Books

Dr Jeffrey Lakritz. "Equine Body Systems and Various Disorders:Anatomy." In UC Davis School of Veterinary Medicine Book ofHorses: A complete medical reference guide for horses and foals. -. New York City: Harper Collins, January 1996.

Dr Jeffrey Lakritz. "Acute respiratory distress syndrome (ARDS) infoals." In 5 Minute Veterinary Consult - Equine. -. Baltimore: Lippincott,Williams and Wilkins Co, January 2002.

Dr Jeffrey Lakritz. "Atypical Interstitial Pneumonia." In 5 Minute Veterinary Consult –Bovine. -. Baltimore: Lippincott, Williams and Wilkins Co, January 2008.

Dr Jeffrey Lakritz, W. David Wilson. "Acute respiratory distress syndrome (ARDS) infoals." In 5 Minute Veterinary Consult - Equine. -. Baltimore, MD: Lippincott,Williams and Wilkins Co, January 2008.

Dr Jeffrey Lakritz. "Winter Dysentery." In 5 Minute Veterinary Consult – Bovine. -. Baltimore: Lippincott, Williams and Wilkins Co, January 2008.

Dr Jeffrey Lakritz. "Lightning Strike." In 5 Minute Veterinary Consult – Bovine. -. Baltimore: Lippincott, Williams and Wilkins Co, January 2008.

Dr Jeffrey Lakritz. "Tongue Trauma." In 5 Minute Veterinary Consult – Bovine. -. Baltimore, MD: Lippincott,Williams and Wilkins Co, January 2008.

Dr Jeffrey Lakritz. "Aspiration Pneumonia." In 5 Minute Veterinary Consult – Bovine. -. Baltimore: Lippincott, Williams and Wilkins Co, January 2008.

Dr Jeffrey Lakritz. "Bovine Papular Stomatitis." In 5 Minute Veterinary Consult – Bovine. -. Baltimore, MD: Lippincott,Williams and Wilkins Co, January 2008.

Dr Jeffrey Lakritz, D. Michael Rings, Bruce L. Hull. "Disorders of the Upper Respiratory Tract in Food Animals." In Current Veterinary Therapy Food Animal Practice Volume #5. Vol. 5th. Edited by David E. Anderson, D. Michael Rings. 199-206. St. Louis, MO, US|USA: Saunders, Elsevier, January 2009.

Sejian V, Shekhawat I, Ujor V, Ezeji T, Lakritz J, Lal R. "Global Climate Change: Enteric Methane Reduction Strategies in Livestock." In Enivronmental Stress and Amelioration in Livestock Production. First ed. Edited by Sejian V, Naqvi SMK, Ezeji T, Lakritz J, Lal R. 1-569. Berlin, Heidelberg, DE|DEU: Springer-Verlag, February 2012.

Wilson WD, Lofstedt J, Valberg SJ, Lakritz J. "Alterations in Respiratory Function." In Large Animal Internal Medicine. Edited by Wilson WD, Lofstedt J, Valberg SJ, Lakritz J. -.

 

Conferences

Jeffrey Lakritz, Alan R. Buckpitt and Charles G. Plopper. "Anatomy of the lung:Structure and Function correlations." Proceedings of the 13th Annu. Veterinary MedicalForum. (January 1994). .

Jeffrey Lakritz, W.D. Wilson. "Acute respiratory distress (ARDS) in foals." Proceedings of the 16th Annu. Veterinary Medical Forum. (January 1997). .

Jeffrey Lakritz, W. David Wilson. "Erythromycin: Pharmacokinetics, bioavailability,non-antimicrobial activity, and possible mechanisms associated with adverse reactions." Proceedings of the American Association of Equine Practitioners. (January 1997). .

Jeffrey Lakritz, Erik R. Wisner, Charles G Plopper. "The respiratory system of thehorse: selected aspects of the functional anatomy and cell biology of normal equinerespiratory system.." Second Dubai International Equine Symposium, Diagnosis andmanagement of equine respiratory disease. (January 1997). .

Dr Jeffrey Lakritz. "Erythromycin: Clinical uses, kinetics and mechanism of action." Proceedings of the 16th Annu. Veterinary Medical Forum. (January 1997). .

Dr Jeffrey Lakritz. "Macrolide antibiotics as anti-inflammatory agents: effects onbronchoalveolar lavage cell populations." 1999 Gordon Research Conference: Nonantimicrobialproperties of tetracylines and other antibiotics.. (January 1999). .

Dr Jeffrey Lakritz. "Non-antimicrobial actions of macrolide antibiotics." Korean Society of Veterinary Science. (January 2000). .

Jeffrey Lakritz, Maisie E. Dawes, Nicolle M. Holloway, Antoinette E. Marsh, Jeff W.Tyler. "Neonatal Passive Transfer of Non-immunoglobulin protein: Lactoferrin’s rolein neonatal immunity." Dorothy Havemeyer Foundation Neonatal Septicemia Workshop #3. (January 2001). .

Jeffrey Lakritz. "Metalloproteinases in bovine respiratory disease." Proceedings of the 24th Veterinary Medical Forum. (June 2005). .

Jeffrey Lakritz. "Gastrointestinal diseases of South American Camelids." Proceedings of the 28th Veterinary Medical Forum. (January 2009). .

 

Edited Books

"Environmental stress and amelioration in livestock production.." 1st ed. Vol. 1. Edited by V. Sejian, MK Syed, T. Naqvi, T. Ezeji, J Lakritz, R. Lal. St. Louis, Missour, US|USA: Elsevier, January 2012.

 

Editorial Activities

2011 - present Enivornmental Stress and amelioration in livestock production.
 

Honors

2001 Faculty Performance Award.
2002 Pfizer Award for Research Excellence.
2013 - present Inventor recognition. OSU Tech Commercialization and Knowledge Transfer.
 

Journal Articles

KENDALL,J,Z; Lakritz,J; WEIR,A,J; PLOPPER,C,G; Randall,G,C; Richards,G,E; Nagamani,M. "MORPHOMETRY OF LUNGS FROM FETAL LAMBS TREATED WITH CORTISOL." PEDIATRIC RESEARCH. Vol. 19, no. 4. (January 1985.): A407-A407.

Lloyd, K, C; Koblik, P; Ragle, C; Wheat, J, D; Lakritz, J. "Incomplete palmar fracture of the proximal extremity of the third metacarpal bone in horses: ten cases (1981-1986).." Journal of the American Veterinary Medical Association. Vol. 192, no. 6. (January 1988.): 798-803.

Kendall, J, Z; Lakritz, J; Plopper, C, G; Richards, G, E; Randall, G, C; Nagamani, M; Weir, A J. "The effects of hydrocortisone on lung structure in fetal lambs.." Journal of developmental physiology. Vol. 13, no. 3. (January 1990.): 165-72.

BAXTER, GM; BROOME, TA; LAKRITZ, J; PARKS, AH; WALLACE, CE. "ALTERNATIVES TO DIGIT AMPUTATION IN CATTLE." COMPENDIUM ON CONTINUING EDUCATION FOR THE PRACTICING VETERINARIAN. Vol. 13, no. 6. (June 1991.): 1022-&.

Lakritz, J; Weir, A, J; Mariassy, A, T; Kendall, J, Z; Plopper, C G. "Ultrastructural morphometric characterization of alveolar type II cells of perinatal sheep: a comparison with adults.." Anatomy and embryology. Vol. 186, no. 4. (January 1992.): 355-62.

Lakritz, J; Madigan, J; Carlson, G P. "Hypovolemic hyponatremia and signs of neurologic disease associated with diarrhea in a foal.." Journal of the American Veterinary Medical Association. Vol. 200, no. 8. (January 1992.): 1114-6.

Kortz, G, D; Madigan, J, E; Lakritz, J; Goetzman, B W. "Cerebral oedema and cerebellar herniation in four equine neonates.." Equine veterinary journal. Vol. 24, no. 1. (January 1992.): 63-6.

Henry, M, M; Morris, D, D; Lakritz, J; Aucoin, D. "Pharmacokinetics of cephradine in neonatal foals after single oral dosing.." Equine veterinary journal. Vol. 24, no. 3. (January 1992.): 242-3.

Wisner, E, R; O'Brien, T, R; Lakritz, J; Pascoe, J, R; Wilson, D, W; Tyler, W S. "Radiographic and microscopic correlation of diffuse interstitial and bronchointerstitial pulmonary patterns in the caudodorsal lung of adult thoroughbred horses in race training.." Equine veterinary journal. Vol. 25, no. 4. (January 1993.): 293-8.

Ward, D, A; Lakritz, J; Bauer, R W. "Scleral mastocytosis in a horse.." Equine veterinary journal. Vol. 25, no. 1. (January 1993.): 79-80.

Lakritz, J; Wilson, W, D; Berry, C, R; Schrenzel, M, D; Carlson, G, P; Madigan, J E. "Bronchointerstitial pneumonia and respiratory distress in young horses: clinical, clinicopathologic, radiographic, and pathological findings in 23 cases (1984-1989).." Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. Vol. 7, no. 5. (January 1993.): 277-88.

Lakritz, J; George, L, W; Moore, J. "Seizures and acute death attributable to hypovitaminosis A and suspected hypovitaminosis D in feeder pigs.." Journal of the American Veterinary Medical Association. Vol. 202, no. 8. (January 1993.): 1276-8.

Lakritz, J; Wisner, E, R; Finucane, T; O'Brien, T, R; Tyler, W, S; Pascoe, J, R; Plopper, C G. "Morphologic and morphometric characterization of lung collagen content in clinically normal adult thoroughbreds in race training.." American journal of veterinary research. Vol. 56, no. 1. (January 1995.): 11-8.

Lakritz, J; Barr, B, C; George, L, W; Wisner, E, R; Glenn, J, S; East, N, E; Pool, R R. "Cervical and thoracic vertebral malformation ("weak neck") in Colombia lambs.." Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. Vol. 9, no. 6. (January 1995.): 393-8.

Lakritz, J; Chang, AM; Weir, A; Nishio, S; Philpot, R; Hyde, D; Buckpitt, A; Plopper, C. "Cellular and metabolic basis of clara cell tolerance to multiple doses of cytochrome P450-activated cytotoxicants .1. Bronchiolar epithelial reorganization and expression of cytochrome P450 monooxygenases in mice exposed to multiple doses of naphthalene." JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS. Vol. 278, no. 3. (September 1996.): 1408-1418.

Marsh, A, E; Barr, B, C; Madigan, J; Lakritz, J; Nordhausen, R; Conrad, P A. "Neosporosis as a cause of equine protozoal myeloencephalitis.." Journal of the American Veterinary Medical Association. Vol. 209, no. 11. (January 1996.): 1907-13.

Marsh, A, E; Barr, B, C; Madigan, J; Lakritz, J; Conrad, P A. "Sequence analysis and polymerase chain reaction amplification of small subunit ribosomal DNA from Sarcocystis neurona.." American journal of veterinary research. Vol. 57, no. 7. (January 1996.): 975-81.

Lakritz, J; Wilson, W, D; Watson, J, L; Hyde, D, M; Mihalyi, J; Plopper, C G. "Effect of treatment with erythromycin on bronchoalveolar lavage fluid cell populations in foals.." American journal of veterinary research. Vol. 58, no. 1. (January 1997.): 56-61.

Marsh, AE; Barr, BC; Lakritz, J; Nordhausen, R; Madigan, JE; Conrad, PA. "Experimental infection of nude mice as a model for Sarcocystis neurona-associated encephalitis." PARASITOLOGY RESEARCH. Vol. 83, no. 7. (July 1997.): 706-711.

Lakritz, J; Plopper, C, G; Buckpitt, A R. "Validated high-performance liquid chromatography-electrochemical method for determination of glutathione and glutathione disulfide in small tissue samples.." Analytical biochemistry. Vol. 247, no. 1. (January 1997.): 63-8.

Mitchell, A, E; Morin, D; Lakritz, J; Jones, A D. "Quantitative profiling of tissue- and gender-related expression of glutathione S-transferase isoenzymes in the mouse.." The Biochemical journal. Vol. 325 ( Pt 1), (January 1997.): 207-16.

Lakritz,J. "Effect of treatment with erythromycin on bronchoalveolar lavage fluid cell populations in foals (vol 58, pg 56, 1997)." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 58, no. 4. (April 1997.): 337-337.

Lakritz, J; Wilson, WD; Mihalyi, JE. "Comparison of microbiologic and high-performance liquid chromatography assays to determine plasma concentrations, pharmacokinetics, and bioavailability of erythromycin base in plasma of foals after intravenous or intragastric administration." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 60, no. 4. (April 1999.): 414-419.

Lakritz, J; Winder, B, S; Noorouz-Zadeh, J; Huang, T, L; Buckpitt, A, R; Hammock, B, D; Plopper, C G. "Hepatic and pulmonary enzyme activities in horses.." American journal of veterinary research. Vol. 61, no. 2. (January 2000.): 152-7.

Lakritz, J; Wilson, W, D; Marsh, A, E; Mihalyi, J E. "Pharmacokinetics of erythromycin estolate and erythromycin phosphate after intragastric administration to healthy foals.." American journal of veterinary research. Vol. 61, no. 8. (January 2000.): 914-9.

Lakritz, J; Wilson, W, D; Marsh, A, E; Mihalyi, J E. "Effects of prior feeding on pharmacokinetics and estimated bioavailability after oral administration of a single dose of microencapsulated erythromycin base in healthy foals.." American journal of veterinary research. Vol. 61, no. 9. (January 2000.): 1011-5.

Tyler, J, W; Lakritz, J; Hostetler, D, E; Douglas, V; Weaver, D, M; Steevens, B, J; Holle, J; Denbigh, J. "Effect of pasteurization at 76 and 63 degrees C on the absorption of colostral IgG in calves.." The Journal of dairy research. Vol. 67, no. 4. (January 2000.): 619-23.

Mitchell, A, E; Lakritz, J; Jones, A D. "Quantification of individual glutathione S-transferase isozymes in hepatic and pulmonary tissues of naphthalene-tolerant mice.." Archives of toxicology. Vol. 74, no. 4-5. (January 2000.): 215-21.

Lakritz, J; Tyler, JW; Hostetler, DE; Marsh, AE; Weaver, DM; Holle, JM; Steevens, BJ; Denbigh, JL. "Effects of pasteurization of colostrum on subsequent serum lactoferrin concentration and neutrophil superoxide production in calves." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 61, no. 9. (September 2000.): 1021-1025.

Tessman, R, K; Lakritz, J; Tyler, J, W; Casteel, S, W; Williams, J, E; Dew, R K. "Sensitivity and specificity of serum copper determination for detection of copper deficiency in feeder calves.." Journal of the American Veterinary Medical Association. Vol. 218, no. 5. (January 2001.): 756-60.

Holloway, NM; Tyler, JW; Lakritz, J; Carlson, SL; Holle, J. "Serum immunoglobulin G concentrations in calves fed fresh and frozen colostrum." JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION. Vol. 219, no. 3. (August 2001.): 357-359.

Marsh, A, E; Mullins, A, L; Lakritz, J. "In vitro quantitative analysis of (3)H-uracil incorporation by Sarcocytis neurona to determine efficacy of anti-protozoal agents.." Veterinary parasitology. Vol. 95, no. 2-4. (January 2001.): 241-9.

Plopper, CG; Buckpitt, A; Evans, M; Van Winkle, L; Fanucchi, M; Smiley-Jewell, S; Lakritz, J; West, J; Lawson, G; Paige, R; Miller, L; Hyde, D. "Factors modulating the epithelial response to toxicants in tracheobronchial airways." TOXICOLOGY. Vol. 160, no. 1-3. (March 2001.): 173-180.

Zheng, J; Plopper, C, G; Lakritz, J; Storms, D, H; Hammock, B D. "Leukotoxin-diol: a putative toxic mediator involved in acute respiratory distress syndrome.." American journal of respiratory cell and molecular biology. Vol. 25, no. 4. (January 2001.): 434-8.

Tyler, JW; Lakritz, J; Weaver, D; Johnson, G; VanMetre, D; Smith, K; Taylor, W; Jenny, A. "The 14-3-3 cerebrospinal fluid immunoassay lacks utility in the diagnosis of clinical scrapie." JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION. Vol. 13, no. 6. (November 2001.): 537-539.

Nagy, DW; Lakritz, J; Tyler, JW; Jarboe, J; Loiacono, CM; Haddad, MF. "The treatment of suspected cerebrospinal nematodiasis with moxidectin in 3 llamas (Llama glama)." JOURNAL OF CAMEL PRACTICE AND RESEARCH. Vol. 9, no. 2. (December 2002.): 145-149.

Tyler, JW; Miller, RB; Constable, PD; Hostetler, DE; Lakritz, J; Hardin, DK; Angel, KL; Wolfe, DF. "Factors related to in-house agricultural animal caseloads in US veterinary teaching hospitals." JOURNAL OF VETERINARY INTERNAL MEDICINE. Vol. 16, no. 1. (January 2002.): 7-11.

Butcher, M; Lakritz, J; Halaney, A; Branson, K; Gupta, G, D; Kreeger, J; Marsh, A E. "Experimental inoculation of domestic cats (Felis domesticus) with Sarcocystis neurona or S. neurona-like merozoites.." Veterinary parasitology. Vol. 107, no. 1-2. (January 2002.): 1-14.

Lakritz, J; Wilson, WD. "Erythromycin and other macrolide antibiotics for treating Rhodococcus equi pneumonia in foals." COMPENDIUM ON CONTINUING EDUCATION FOR THE PRACTICING VETERINARIAN. Vol. 24, no. 3. (March 2002.): 256-261.

Holloway, NM; Tyler, JW; Lakritz, J; Carlson, SL; Tessman, RK; Holle, J. "Serum immunoglobulin G concentrations in calves fed fresh colostrum or a colostrum supplement." JOURNAL OF VETERINARY INTERNAL MEDICINE. Vol. 16, no. 2. (March 2002.): 187-191.

Dawes, ME; Tyler, JW; Hostetler, D; Lakritz, J; Tessman, R. "Evaluation of a commercially available immunoassay for assessing adequacy of passive transfer in calves." JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION. Vol. 220, no. 6. (March 2002.): 791-793.

Holloway, NM; Lakritz, J; Tyler, JW; Carlson, SL. "Serum lactoferrin concentrations in colostrum-fed calves." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 63, no. 4. (April 2002.): 476-478.

Lakritz, Jeffrey; Tyler, Jeff, W; Marsh, Antoinette, E; Romesburg-Cockrell, Mary; Smith, Kathy; Holle, Julie M. "Tilmicosin reduces lipopolysaccharide-stimulated bovine alveolar macrophage prostaglandin E(2) production via a mechanism involving phospholipases.." Veterinary therapeutics : research in applied veterinary medicine. Vol. 3, no. 1. (January 2002.): 7-21.

Marsh, AE; Hyun, C; Barr, BC; Tindall, R; Lakritz, J. "Characterization of monoclonal antibodies developed against Sarcocystic neurona." PARASITOLOGY RESEARCH. Vol. 88, no. 6. (June 2002.): 501-506.

Lakritz,Jeffrey; Wilson,W,David; Marsh,Antoinette,E; Mihalyi,Judy,E. "Pharmacokinetics of erythromycin ethylsuccinate after intragastric administration to healthy foals.." Veterinary therapeutics. Vol. 3, no. 2. (June 2002.): 189-195.

Lakritz, J; Leonard, MJ; Eichen, PA; Rottinghaus, GE; Johnson, GC; Spiers, DE. "Whole-blood concentrations of glutathione in cattle exposed to heat stress or a combination of heat stress and endophyte-infected tall fescue toxins in controlled environmental conditions." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 63, no. 6. (June 2002.): 799-803.

Gupta, GD; Lakritz, J; Kim, JH; Kim, DY; Kim, JK; Marsh, AE. "Seroprevalence of Neospora, Toxoplasma gondii and Sarcocystis neurona antibodies in horses from Jeju island, South Korea." VETERINARY PARASITOLOGY. Vol. 106, no. 3. (June 2002.): 193-201.

Chakwenya, J; Lakritz, J; Tyler, J; Fales, WH; James-Kracke, M; Smith, K; Holle, J. "Pharmacokinetics and bioavailability of trimethoprim-sulfamethoxazole in alpacas." JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS. Vol. 25, no. 5. (October 2002.): 321-327.

Middleton, JR; Hebert, VR; Fox, LK; Tomaszewska, E; Lakritz, J. "Elimination kinetics of chlorhexidine in milk following intramammary infusion to stop lactation in mastitic mammary gland quarters of cows." JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION. Vol. 222, no. 12. (June 2003.): 1746-1749.

Youn, H, J; Lakritz, J; Kim, D, Y; Rottinghaus, G, E; Marsh, A E. "Anti-protozoal efficacy of medicinal herb extracts against Toxoplasma gondii and Neospora caninum.." Veterinary parasitology. Vol. 116, no. 1. (January 2003.): 7-14.

Morandi, F; Mattoon, JS; Lakritz, J; Turk, JR; Wisner, ER. "Correlation of helical and incremental high-resolution thin-section computed tomographic imaging with histomorphometric quantitative evaluation of lungs in dogs." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 64, no. 7. (July 2003.): 935-944.

Ramos-Vara, J, A; Loiacono, C, M; Williams, F 3rd; Pardo, I; Lakritz, J. "Pulmonary neoplasia in two llamas (Lama glama).." Veterinary pathology. Vol. 41, no. 5. (January 2004.): 520-3.

Gupta, G, D; Lakritz, J; Saville, W, J; Livingston, R, S; Dubey, J, P; Middleton, J, R; Marsh, A E. "Antigenic evaluation of a recombinant baculovirus-expressed Sarcocystis neurona SAG1 antigen.." The Journal of parasitology. Vol. 90, no. 5. (January 2004.): 1027-33.

Dawes, Maisie, E; Lakritz, Jeffrey; Tyler, Jeff, W; Cockrell, Mary; Marsh, Antoinette, E; Estes, D Mark; Larson, Robert, L; Steevens, Barry. "Effects of supplemental lactoferrin on serum lactoferrin and IgG concentrations and neutrophil oxidative metabolism in Holstein calves.." Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. Vol. 18, no. 1. (January 2004.): 104-8.

Youn, HJ; Lakritz, J; Rottinghaus, GE; Seo, HS; Kim, DY; Cho, MH; Marsh, AE. "Anti-protozoal efficacy of high performance liquid chromatography fractions of Torilis japonica and Sophora flavescens extracts on Neospora caninum and Toxoplasma gondii." VETERINARY PARASITOLOGY. Vol. 125, no. 3-4. (November 2004.): 409-414.

Wilson, A, P; Thelen, J, J; Lakritz, J; Brown, C, R; Marsh, A E. "The identification of a sequence related to apicomplexan enolase from Sarcocystis neurona.." Parasitology research. Vol. 94, no. 5. (January 2004.): 354-60.

Marsh, AE; Lakritz, J; Johnson, PJ; Miller, MA; Chiang, YW; Chu, HJ. "Evaluation of immune responses in horses immunized using a killed Sarcoystis neurona vaccine." VETERINARY THERAPEUTICS. Vol. 5, no. 1. (January 2004.): 34-42.

Lakritz, Jeffrey; Marsh, Antoinette, E; Cockrell, Mary; Smith, Michael, F; Tyler, Jeff W. "Characterization of gelatinases in bronchoalveolar lavage fluid and gelatinases produced by alveolar macrophages isolated from healthy calves.." American journal of veterinary research. Vol. 65, no. 2. (January 2004.): 163-72.

Morandi, F; Mattoon, JS; Lakritz, J; Turk, JR; Jaeger, JQ; Wisner, ER. "Correlation of helical and incremental high-resolution thin-section computed tomographic and histomorphometric quantitative evaluation of an acute inflammatory response of lungs in dogs." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 65, no. 8. (August 2004.): 1114-1123.

Middleton, JR; Timms, LL; Bader, R; Lakritz, J; Luby, CD; Steevens, BJ. "Effect of prepartum intramarnmary treatment with pirlimycin hydrochloride on prevalence of early first-lactation mastitis in dairy heifers." JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION. Vol. 227, no. 12. (December 2005.): 1969-1974.

Shin, YS; Shin, GW; Kim, YR; Lee, EY; Yang, HH; Palaksha, KJ; Youn, HJ; Kim, JH; Kim, DY; Marsh, AE; Lakritz, L; Jung, TS. "Comparison of proteome and antigenic proteome between two Neospora caninum isolates." VETERINARY PARASITOLOGY. Vol. 134, no. 1-2. (November 2005.): 41-52.

Lakritz, J; Middleton, JR; Anderson, DE; Linden, DR; Sams, RA; Tessman, RK; Tyler, JW. "Pharmacokinetics of intravenously administered caffeine in healthy alpacas (Lama pacos) and Ilamas (Lama glama)." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 67, no. 6. (June 2006.): 1063-1069.

Linden,Daniel,R; Anderson,David,E; Lakritz,Jeff; Rings,D,Michael; Ramsey,Pauil,M; Evans,Norman. "Apparent digestibility of organic zinc forms in llama (Lama glama) and alpaca (Lama pacos)." JOURNAL OF CAMEL PRACTICE AND RESEARCH. Vol. 14, no. 2. (December 2007.): 181-185.

Bannikov, Gregory, A; Mattoon, John, S; Abrahamsen, Eric, J; Premanandan, Christopher; Green-Church, Kari, B; Marsh, Antoinette, E; Lakritz, Jeffrey. "Biochemical and enzymatic characterization of purified covalent complexes of matrix metalloproteinase-9 and haptoglobin released by bovine granulocytes in vitro.." American journal of veterinary research. Vol. 68, no. 9. (January 2007.): 995-1004.

Dawes, ME; Tyler, JW; Marsh, AE; Larson, RL; Steevens, BJ; Lakritz, J. "In vitro effects of lactoferrin on lipopolysaccharide-induced proliferation, gene expression, and prostanoid production by bovine peripheral blood mononuclear cells." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 69, no. 9. (September 2008.): 1164-1170.

Gerspach, C; Hull, BL; Rings, DM; Chew, DJ; Beamer, GL; Hubbell, JAE; Lakritz, J. "Hematuria and transitional cell papilloma of the renal pelvis treated via unilateral nephrectomy in an alpaca." JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION. Vol. 232, no. 8. (April 2008.): 1206-1209.

Newman, KA; Rajala-Schultz, PJ; Lakritz, J; DeGraves, F. "Lactoferrin concentrations in bovine milk prior to dry-off." JOURNAL OF DAIRY RESEARCH. Vol. 76, no. 4. (November 2009.): 426-432.

Bannikov, GA; Lakritz, J; Premanandan, C; Mattoon, JS; Abrahamsen, EJ. "Kinetics of inhibition of purified bovine neutrophil matrix metalloproteinase 9 by low-molecular-weight inhibitors." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 70, no. 5. (May 2009.): 633-639.

Varga, A; Schober, KE; Holloman, CH; Stromberg, PC; Lakritz, J; Rings, DM. "Correlation of Serum Cardiac Troponin I and Myocardial Damage in Cattle with Monensin Toxicosis." JOURNAL OF VETERINARY INTERNAL MEDICINE. Vol. 23, no. 5. (September 2009.): 1108-1116.

Varga, A; Schober, KE; Walker, WL; Lakritz, J; Michael Rings, D. "Validation of a Commercially Available Immunoassay for the Measurement of Bovine Cardiac Troponin I." JOURNAL OF VETERINARY INTERNAL MEDICINE. Vol. 23, no. 2. (March 2009.): 359-365.

Newman, KA; Rajala-Schultz, PJ; DeGraves, FJ; Lakritz, J. "Association of milk yield and infection status at dry-off with intramammary infections at subsequent calving." JOURNAL OF DAIRY RESEARCH. Vol. 77, no. 1. (February 2010.): 99-106.

Gerspach,C; Bateman,S; Sherding,R; Chew,D,J; Besier,A,S; Grieves,J,L; Lakritz,J. "Acute Renal Failure and Anuria Associated with Vitamin D Intoxication in Two Alpaca (Vicugna pacos) Cria." JOURNAL OF VETERINARY INTERNAL MEDICINE. Vol. 24, no. 2. (March 2010.): 443-449.

Sejian, V; Lal, R; Lakritz, J; Ezeji, T. "Measurement and prediction of enteric methane emission." INTERNATIONAL JOURNAL OF BIOMETEOROLOGY. Vol. 55, no. 1. (January 2011.): 1-16.

Sejian V, Rotz A, Lakritz J, Ezeji T, Lal R.. "Modeling of greenhouse gas emissions in a dairy farm.." Journal of Animal Science Advances. Vol. 1, (January 2011.): 12-20.

Sejian V, Lal R, Lakritz J, Ezeji T.. "Measurement and prediction of enteric methane emission.." International Journal of Biometeorology. Vol. 1, no. 55. (January 2011.): 1-16.

Bannikov, GA; Hinds, CA; Rajala-Schultz, PJ; Premanandan, C; Rings, DM; Lakritz, J. "Serum haptoglobin-matrix metalloproteinase 9 (Hp-MMP 9) complex as a biomarker of systemic inflammation in cattle." VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. Vol. 139, no. 1. (January 2011.): 41-49.

Sejian, V; Lakritz, J; Ezeji, T; Lal, R. "Assessment Methods and Indicators of Animal Welfare." ASIAN JOURNAL OF ANIMAL AND VETERINARY ADVANCES. Vol. 6, no. 4. (April 2011.): 301-315.

Suzuki,Kazuyuki; Higuchi,Hidetoshi; Iwano,Hidetomo; Lakritz,Jeffrey; Sera,Kouichiro; Koiwa,Masateru; Taguchi,Kiyoshi. "Analysis of Trace and Major Elements in Bronchoalveolar Lavage Fluid of Mycoplasma Bronchopneumonia in Calves." BIOLOGICAL TRACE ELEMENT RESEARCH. Vol. 145, no. 2. (February 2012.): 166-171.

Kelmer G, Martin-Jimenez T, Saxton AM, Catasus C, Elliott SB, Lakritz J. "Evaluation of regional limb perfusion with erythromycin using the saphenous, cephalic or palmar digital veins in standing horses.." Journal of Veterinary Pharmacology and Therapeutics. Vol. 36, (December 2012.): 236–240-.

Pentecost RL, Marsh AE, Niehaus AJ, Daleccio J, Daniels JB, Rajala-Schultz PJ, Lakritz J. "Vertical transmission of Mycoplasma haemolamae in Alpacas (Vicugna pacos).." Small Ruminant Research. Vol. 106, no. 2-3. (January 2012.): 181-188.

Walker WL, Epperson WB, Wittum TE, Lord LK, Rajala-Schultz PJ, Lakritz J. "Characteristics of dairy calf ranches in the United States: Morbidity, mortality, antibiotic use practices and biosecurity and biocontainment practices." Journal of Dairy Science. Vol. 95, no. 4. (April 2012.): 2204-2214.

Suzuki,K; Uchida,E; Schober,K,E; Niehaus,A; RINGS,M,D; Lakritz,J. "Cardiac Troponin I in Calves with Congenital Heart Disease." JOURNAL OF VETERINARY INTERNAL MEDICINE. Vol. 26, no. 4. (July 2012.): 1056-1060.

Aarnes,Turi,K; Fry,Pamela,R; Hubbell,John,AE; Bednarski,Richard,M; Lerche,Phillip; Chen,Wei; Bei,Di; Liu,Zhongfa; Lakritz,Jeffrey. "Pharmacokinetics and pharmacodynamics of midazolam after intravenous and intramuscular administration in alpacas." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 74, no. 2. (February 2013.): 294-299.

Fraser,Brandon,C; Anderson,David,E; White,Brad,J; Miesner,Matt,D; Wheeler,Carrie; Amrine,David; Lakritz,Jeff; Overbay,Tom. "Assessment of a commercially available point-of-care assay for the measurement of bovine cardiac troponin I concentration." AMERICAN JOURNAL OF VETERINARY RESEARCH. Vol. 74, no. 6. (June 2013.): 870-873.

Theurer,M,E; Anderson,D,E; White,B,J; Miesner,M,D; Mosier,D,A; Coetzee,J,F; Lakritz,J; Amrine,D,E. "Effect of Mannheimia haemolytica pneumonia on behavior and physiologic responses of calves during high ambient environmental temperatures." JOURNAL OF ANIMAL SCIENCE. Vol. 91, no. 8. (August 2013.): 3917-3929.

Pentecost,Rebecca,L; Niehaus,Andrew,J; Werle,Nick,A; Lakritz,Jeffrey. "Pharmacokinetics of florfenicol after intravenous and intramuscular dosing in llamas." RESEARCH IN VETERINARY SCIENCE. Vol. 95, no. 2. (October 2013.): 594-599.

Hubbell JAE, Kelly EM, Aarnes TK, Bednarski RM, Lerche P, Liu Z, Lakritz J.. "Pharmacokinetics of midazolam following intravenous administration to horses.." Equine Veterinary Journal. Vol. 45:721-725, (October 2013.): 721-725.

Daniels JB, Tracey G, Irom SJ, Lakritz J.. "Fluoroquinolone levels in healthy dog urine following a 20 mg/kg oral dose of enrofloxacin exceed mutant prevention concentration targets against Escherichia coli isolated from canine urinary tract infections.." Journal of Veterinary Pharmacology and Therapeutics. Vol. 37, no. 3. (July 2013.): 1-4.

Van Engen NK, Stock ML, Engelken T, Vann R, Wulf LW, Karriker LA, Busby WD, Lakritz J, Bradford B, Hsu W, Wang C, Coetzee JF.. "Impact of oral meloxicam on circulating physiological parameters in beef steers after long distance transportation.." Journal of Animal Science. -.

 

Inventions and Patents

Dr Jeffrey Lakritz. "ELISA FOR HAPTOGLOBIN-MATRIX METALLOPROTEINASE 9 COMPLEX AS A DIAGNOSTIC TEST FOR CONDITIONS INCLUDING ACUTE INFLAMMATION." United States Department of Agriculture. Filed August 2010.

Dr Jeffrey Lakritz. "Elisa for Haptoglobin-Matrix Metalloproteinase 9 Complex as a Diagnostic Test for Conditions Including Acute Inflammation." USDA. Filed August 2011.

 

Unpublished Works

CA Hinds, AJ Niehaus, C Premanandan, PJ Rajala-Schultz, DM Rings, J Lakritz.. Serum neutrophil haptoglobin-matrix metalloproteinase 9 (Hp-MMP 9) responses in calves following a single Intravenous dose of Lipopolysaccharide..