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Ian C. Davis, DVM, PhD


1925 Coffey Rd
Columbus, OH 43210

Phone: (614) 292-2954

Email: davis.2448@osu.edu

 

Current OSU Appointment

Associate Professor, Veterinary Biosciences

 

Licenses

present Eligible for board certification: American College of Laboratory Animal Medicine
 

Chapters in Books

Davis, I., and Matalon, S.. "Role of reactive oxygen and nitrogen species in the pathogenesis of pulmonary viral infections.." In Etiology and treatment of acute lung injury: From bench to bedside.. Vol. 336. Edited by Claude Lenfant; Section Editors: Matalon, S., and Sznajder, J.I.. 237-247. Amsterdam, NL|NLD: ISO Press, January 2001.

Hickman-Davis, J.M., Davis, I.C., O'Reilly, P., McArdle, P., Matalon, S.. "Do reactive oxygen-nitrogen intermediates contribute to the pathogenesis of ARDS?." In Disease Markers in Exhaled Breath. Vol. 346. Edited by Claude Lenfant; Section Editors: N. Marczin and M.H. Yacoub. 344-353. Amsterdam, NL|NLD: IOS Press, January 2002.

Davis, I.C., Prince, L.S., and Matalon, S.. "Epithelial sodium channel function in health and disease in the adult lung." In Ion channels in the pulmonary vasculature. Vol. 197. Edited by Yuan, H.. 185-198. Boca Raton, FL: Taylor & Francis Group, January 2005.

Davis, I.C., Lang, J.D., and Matalon, S.. "Roles of reactive oxygen and nitrogen species in lung injury.." In Lung injury: Mechanisms, pathophysiology, and therapy.. Vol. 196. Edited by R.H. Notter, J.N. Finkelstein, and B.A. Holm. 227-268. Boca Raton, FL: Taylor and Francis, January 2005.

Davis, I.C., and Matalon, S.. "Epithelial sodium channels in the adult lung – Important modulators of pulmonary health and disease." In Hypoxia and the circulation. Vol. Volume 618. Edited by Roach, R.C., Wagner, P.D., and Hackett, P.H.. 127-140. New York, NY: Springer, January 2007.

Lang, J.D., Davis, I.C., Patel, R.P., and Matalon, S.. "Oxidative and nitrosative lung injury." In Pulmonary Diseases and Disorders, 4th Edition. Edited by Fishman, Elias, Fishman, Grippi, Senior, and Pack. 359-. New York, NY: McGraw-Hill, January 2007.

 

Conferences

Davis, I.C., Fultz, P.N.. "Lymphocyte apoptosis associated with in vitro SIVsmmPBj14 infection." 15th Annual Symposium on Nonhuman Primate Models for AIDS. (January 1998). 175-175.

Davis, I.C., McGinn, T.M., Fultz, P.N.. "Rapid induction of CD4+ T-cell apoptosis in peripheral blood after rectal inoculation of pig-tailed macaques with SIVsmmPBj14." 16th Annual Symposium on Nonhuman Primate Models for AIDS. (January 1999). 292-292.

Chen, Z.W., Shen, Y., Davis, I.C., Letvin, N.L., Fultz, P.N.. "Dynamics of T-cell receptor repertoires in lymphoid compartments of macaques rectally inoculated with SIVsmmPBj14." 17th Annual Symposium on Nonhuman Primate Models for AIDS. (January 2000). 281-281.

Davis, I.C., Nolte, K., Hjelle, B., Matalon, S.. "Elevated production of reactive oxygen/nitrogen species associated with hantavirus cardiopulmonary syndrome." Am. J. Resp. Crit. Care Med.. (January 2001). A814-.

Davis, I.C., Matalon, S., Fultz, P.N.. "A possible role for reactive nitrogen species in the pathogenesis of acute lethal disease induced by SIV-PBj14." 18th Annual Symposium on Nonhuman Primate Models for AIDS. (January 2001). 225-225.

McGinn, T.M., Davis, I.C., Stallworth, J.W., May, P.A., Fultz, P.N.. "Natural history of STLV-1 and HTLV-1ach infection of pig-tailed macaques." 18th Annual Symposium on Nonhuman Primate Models for AIDS. (January 2001). 240-240.

Hickman-Davis, J.M., Davis, I.C., Peti-Peterdi, J., O’Reilly, P., Young, K.R., Matalon, S.. "SP-A stimulates phagocytosis of Klebsiella pneumoniae by human alveolar macrophages in vitro." 98th International Conference of the American Thoracic Society, Atlanta, GA. (January 2002). A80-.

Davis, I.C., Sullender, W.M., Matalon, S.. "Respiratory syncytial virus (RSV) inhibits Na+ ion transport by murine respiratory epithelial cells in vitro and in vivo." 98th International Conference of the American Thoracic Society, Atlanta, GA. (January 2002). A612-.

Davis, I.C., Lazrak, A., Sullender, W.M., Matalon, S.. "Respiratory syncytial virus (RSV) inhibits whole cell Na+ currents in A549 cells." Experimental Biology, New Orleans, LA. (January 2002). A411-.

Davis, I.C., Sullender, W.M., Matalon, S.. "Respiratory syncytial virus (RSV) inhibits alveolar fluid clearance in the mouse." 99th International Conference of the American Thoracic Society, Seattle, WA. (January 2003). A59-.

Webster-Marketon, J.I., Clagett, A.M., Davis, I.C.. "Dysregulation of glucocorticoid receptor (GR) signaling by respiratory syncytial virus." 105th International Conference of the American Thoracic Society, San Diego, CA. (January 2009). A1936-.

 

Editorial Activities

present Wellcome Trust
present Medical Research Council (U.K.)
present Journal of Virological Methods
present International Immunopharmacology
present Critical Care Medicine
present American Journal of Respiratory Cell and Molecular Biology
present American Journal of Respiratory and Critical Care Medicine
present American Journal of Physiology: Lung Cellular and Molecular Physiology
present American Heart Association
present Journal of General Virology
present Journal of Applied Physiology
present Free Radical Biology and Medicine
present Veterans Administration
present PLoS One
present Journal of Thrombosis and Hemostasis
present Virology
present American Journal of Physiology: Regulatory, Integrative and Comparative Physiology
present Journal of Critical Care
2010 - present American Journal of Respiratory Cell and Molecular Biology
2012 - present American Journal of Physiology (Lung Cellular and Molecular Physiology)
 

Honors

1988 - 1999 Intercalated Degree studies. Burroughs-Wellcome Foundation.
1989 First class honors.
1989 Prize for highest marks in final examinations.
1990 - 1991 Veterinary Student of the Year. Centaur Society.
1991 Cornell University Summer Veterinary Research Program. Geraldine R. Dodge Foundation.
1992 Bachelor of Veterinary Sciences degree with honors.
1997 - 2000 T32 Training Grant. NIAID.
2001 - 2003 Research Training Fellowship. American Lung Association.
2001 - 2004 Fellowship. Parker B. Francis Family Foundation.
2002 Julius Comroe EB Travel Award. American Physiological Society (Respiration Section).
2004 Young Scientist Travel Award. European Respiratory Society.
2010 - present Giles F. Filley Memorial Award for Excellence in Respiratory Physiology and Medicine. American Physiological Society.
 

Journal Articles

Davis IC; Owen RL. "The immunopathology of M cells.." Springer Seminars In Immunopathology. Vol. 18, no. 4. (January 1997.): 421-448.

Davis, I, C; Girard, M; Fultz, P N. "Loss of CD4+ T cells in human immunodeficiency virus type 1-infected chimpanzees is associated with increased lymphocyte apoptosis.." Journal of virology. Vol. 72, no. 6. (January 1998.): 4623-4632.

Wang, D; Yuan, W; Davis, I; Parrish, C R. "Nonstructural protein-2 and the replication of canine parvovirus.." Virology. Vol. 240, no. 2. (January 1998.): 273-281.

Conry, R, M; White, S, A; Fultz, P, N; Khazaeli, M, B; Strong, T, V; Allen, K, O; Barlow, D, L; Moore, S, E; Coan, P, N; Davis, I; Curiel, D, T; LoBuglio, A F. "Polynucleotide immunization of nonhuman primates against carcinoembryonic antigen.." Clinical cancer research : an official journal of the American Association for Cancer Research. Vol. 4, no. 11. (January 1998.): 2903-2912.

Fultz, P, N; McGinn, T; Davis, I, C; Romano, J, W; Li, Y. "Coinfection of macaques with simian immunodeficiency virus and simian T cell leukemia virus type I: effects on virus burdens and disease progression.." The Journal of infectious diseases. Vol. 179, no. 3. (January 1999.): 600-611.

Chen, Z, W; Shen, Y; Davis, I, C; Shen, L; Letvin, N, L; Fultz, P N. "Down-regulation of macaque gammadelta + T cells in lymphoid compartments after rectal infection with SIVsmmPBj14.." Journal of medical primatology. Vol. 29, no. 3-4. (January 2000.): 143-147.

Fultz, P, N; Vance, P, J; Endres, M, J; Tao, B; Dvorin, J, D; Davis, I, C; Lifson, J, D; Montefiori, D, C; Marsh, M; Malim, M, H; Hoxie, J A. "In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail.." Journal of virology. Vol. 75, no. 1. (January 2001.): 278-291.

Ian C. Davis and Sadis Matalon. "Reactive species in viral pneumonitis - lessons from animal models.." News Physiol Sci. Vol. 16, (January 2001.): 185-190.

Hickman-Davis, Judy, M; O'Reilly, Philip; Davis, Ian, C; Peti-Peterdi, Janos; Davis, Glenda; Young, K Randall; Devlin, Robert, B; Matalon, Sadis. "Killing of Klebsiella pneumoniae by human alveolar macrophages.." American journal of physiology. Lung cellular and molecular physiology. Vol. 282, no. 5. (January 2002.): L944-L956.

Davis, Ian, C; Zhu, Sha; Sampson, Jacinda, B; Crow, John, P; Matalon, Sadis. "Inhibition of human surfactant protein A function by oxidation intermediates of nitrite.." Free radical biology & medicine. Vol. 33, no. 12. (January 2002.): 1703-1713.

Davis, Ian, C; Zajac, Allan, J; Nolte, Kurt, B; Botten, Jason; Hjelle, Brian; Matalon, Sadis. "Elevated generation of reactive oxygen/nitrogen species in hantavirus cardiopulmonary syndrome.." Journal of virology. Vol. 76, no. 16. (January 2002.): 8347-8359.

McGinn, Therese, M; Tao, Binli; Cartner, Samuel; Schoeb, Trenton; Davis, Ian; Ratner, Lee; Fultz, Patricia N. "Association of primate T-cell lymphotropic virus infection of pig-tailed macaques with high mortality.." Virology. Vol. 304, no. 2. (January 2002.): 364-378.

Thome, Ulrich, H; Davis, Ian, C; Nguyen, Susie Vo; Shelton, Brent Jay; Matalon, Sadis. "Modulation of sodium transport in fetal alveolar epithelial cells by oxygen and corticosterone.." American journal of physiology. Lung cellular and molecular physiology. Vol. 284, no. 2. (January 2003.): L376-L385.

Matalon S; Davis IC. "Comment: Vectorial sodium transport across the mammalian alveolar epithelium: it occurs but through which cells?." Circulation Research. Vol. 92, no. 4. (January 2003.): 348-349.

O'Reilly, Philip, J; Hickman-Davis, Judy, M; Davis, Ian, C; Matalon, Sadis. "Hyperoxia impairs antibacterial function of macrophages through effects on actin.." American journal of respiratory cell and molecular biology. Vol. 28, no. 4. (January 2003.): 443-450.

Davis, Ian, C; Sullender, Wayne, M; Hickman-Davis, Judy, M; Lindsey, J Russell; Matalon, Sadis. "Nucleotide-mediated inhibition of alveolar fluid clearance in BALB/c mice after respiratory syncytial virus infection.." American journal of physiology. Lung cellular and molecular physiology. Vol. 286, no. 1. (January 2004.): L112-L120.

Hickman-Davis, Judy, M; McNicholas-Bevensee, Carmel; Davis, Ian, C; Ma, He-Ping; Davis, Glenda, C; Bosworth, Charles, A; Matalon, Sadis. "Reactive species mediate inhibition of alveolar type II cell sodium transport during mycoplasma infection.." American journal of respiratory and critical care medicine. Vol. 173, no. 3. (January 2005.): 334-344.

Hickman-Davis, Judy, M; Davis, Ian C. "Transgenic mice.." Paediatric respiratory reviews. Vol. 7, no. 1. (January 2006.): 49-53.

Davis, Ian, C; Lazarowski, Eduardo, R; Hickman-Davis, Judy, M; Fortenberry, James, A; Chen, Fu-Ping; Zhao, Xiaodong; Sorscher, Eric; Graves, Lee, M; Sullender, Wayne, M; Matalon, Sadis. "Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus." American Journal of Respiratory and Critical Care Medicine. Vol. 173, no. 6. (January 2006.): 673-682.

Davis, Ian, C; Matalon, Sadis. "Epithelial sodium channels in the adult lung--important modulators of pulmonary health and disease.." Advances in experimental medicine and biology. Vol. 618, (January 2007.): 127-140.

Davis, Ian, C; Xu, Anna; Gao, Zhiqian; Hickman-Davis, Judy, M; Factor, Phillip; Sullender, Wayne, M; Matalon, Sadis. "Respiratory syncytial virus induces insensitivity to beta-adrenergic agonists in mouse lung epithelium in vivo.." American journal of physiology. Lung cellular and molecular physiology. Vol. 293, no. 2. (January 2007.): L281-L289.

Davis, Ian, C; Lazarowski, Eduardo, R; Chen, Fu-Ping; Hickman-Davis, Judy, M; Sullender, Wayne, M; Matalon, Sadis. "Post-infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection.." American Journal of Respiratory Cell and Molecular Biology. Vol. 37, no. 4. (January 2007.): 379-386.

Wolk KE; Lazarowski ER; Traylor ZP; Yu EN; Jewell NA; Durbin RK; Durbin JE; Davis IC. "Influenza A virus inhibits alveolar fluid clearance in BALB/c mice.." American Journal Of Respiratory And Critical Care Medicine. Vol. 178, no. 9. (November 2008.): 969-976.

Lai JP; Bao S; Davis IC; Knoell DL. "Inhibition of the phosphatase PTEN protects mice against oleic acid-induced acute lung injury.." British Journal Of Pharmacology. Vol. 156, no. 1. (January 2009.): 189-200.

Chen L; Song W; Davis IC; Shrestha K; Schwiebert E; Sullender WM; Matalon S. "Inhibition of Na+ transport in lung epithelial cells by respiratory syncytial virus infection.." American Journal Of Respiratory Cell And Molecular Biology. Vol. 40, no. 5. (May 2009.): 588-600.

Yu, E.N.Z., Traylor, Z.P., Davis, I.C.. "Effect of ventilation pressure on alveolar fluid clearance and beta-agonist responses in mice.." The American Journal of Physiology - Lung Cellular and Molecular Physiology. Vol. 297, (January 2009.): L785-L793.

Hewitt M; Creel A; Estell K; Davis IC; Schwiebert LM. "Acute exercise decreases airway inflammation, but not responsiveness, in an allergic asthma model.." American Journal Of Respiratory Cell And Molecular Biology. Vol. 40, no. 1. (January 2009.): L83-L89.

Hewitt, M., Estell, K, Davis, I., Schwiebert, L.M.. "Repeated bouts of moderate intensity aerobic exercise reduce airway reactivity in a murine asthma model." American Journal of Respiratory Cell and Molecular Biology. Vol. 42, (January 2010.): 243-249.

Traylor ZP; Yu EN; Davis IC. "Respiratory syncytial virus induces airway insensitivity to beta-agonists in BALB/c mice.." American Journal Of Physiology. Lung Cellular And Molecular Physiology. Vol. 298, no. 3. (March 2010.): L437-L445.

Rennolds, J., Butler, S., Maloney, K., Boyaka, P.N., Davis, I.C., Knoell, D.L., Parinandi, N.L., Cormet-Boyaka, E.. "Cadmium regulates the expression of the CFTR chloride channel in human airway epithelial cells." Toxicological Sciences. Vol. 116, (January 2010.): 349-358.

Aeffner, F., Traylor, Z.P., Yu, E.N.Z., Davis, I.C.. "Double-stranded RNA induces similar pulmonary dysfunctionto respiratory syncytial virus in BALB/c mice." American Journal of Physiology - Lung Cellular and Molecular Physiology. Vol. 301, (July 2011.): L99-L109.

Hinzey, A., Alexander, J., Corry, J., Adams, K.M., Claggett, A.M., Traylor, Z.P., Davis, I.C., Webster-Marketon, J.I.. "Respiratory syncytial virus represses glucocorticoid receptor-mediated gene activation." Endocrinology. Vol. 152, (January 2011.): 483-494.

 

Inventions and Patents

Ian C. Davis. Inventor. "METHOD OF TREATING INFLUENZA BY DISRUPTING AN ADENOSINE RECEPTOR PATHWAY." filed 2010,

Ian C. Davis & Sadis Matalon. Inventor. "Methods of using pyrimidine synthesis inhibitors to increase airway epithelial cell fluid uptake. U.S. P.T.O. # 60/573,558 (status: converted). U.S. P.C.T. application US2005/017939 (status: converted). U.S. pending application #11/569,316.." Issued 2006, (patent pending),

 

Presentations

"Lymphocyte apoptosis associated with in vitro SIVsmmPBj14 infection.." Presented at Annual Symposium on Nonhuman Primate Models for AIDS, Seattle, WA, US|USA. (January 1997)

"Rapid induction of CD4+ T-cell apoptosis in peripheral blood after rectal inoculation of pig-tailed macaques with SIVsmmPBj14." Presented at 16th Annual Symposium on Nonhuman Primate Models for AIDS, Atlanta, GA, US|USA. (January 1998)

"Increased lymphocyte apoptosis associated with loss of CD4+ T cells in chimpanees infected with HIV-1." Presented at Keystone Symposium on HIV Pathogenesis and Treatment, Park City, UT, US|USA. (January 1998)

"Is STLV-I disease progression enhanced in the context of SIV infection?." Presented at 18th Annual Meeting of the American Society for Virology, Amherst, MA, US|USA. (January 1999)

"Dynamics of T cell receptor repertoires in lymphoid compartments of macaques rectally inoculated with SIVsmmPBj14." Presented at 17th Annual Symposium on Nonhuman Primate Models for AIDS, New Orleans, LA, US|USA. (January 1999)

"Rectal inoculation of macaques with SIV-PBj14 rapidly induces CD4 and CD8 T-cell apoptosis." Presented at 18th Annual Meeting of the American Society for Virology, Amherst, MA, US|USA. (January 1999)

"Differences in early pathogenesis after parenteral and mucosal inoculation of pig-tailed macaques with SIV-PBj14-BCL3." Presented at 17th Annual Symposium on Nonhuman Primate Models for AIDS, New Orleans, LA, US|USA. (January 1999)

"Association of nitric oxide with PTLV infections of pig-tailed macaques." Presented at 19th Annual Meeting of the American Society for Virology, Fort Collins, CO, US|USA. (January 2000)

"Elevated production of reactive oxygen/nitrogen species associated with hantavirus cardiopulmonary syndrome." Presented at 97th International Conference of the American Thoracic Society, San Francisco, CA, US|USA. (January 2001)

"Respiratory syncytial virus modulates epithelial sodium conductance.." Presented at 20th Annual Meeting of the American Society for Virology, Madison, WI, US|USA. (January 2001)

"Inhibition of sodium transport across airway epithelial cells by respiratory syncytial virus: Mechanisms and pathophysiological implications.." Presented at 99th International Conference of the American Thoracic Society, Seattle, WA, US|USA. (January 2003)

"Nucleotide inhibition of amiloride-sensitive alveolar fluid clearance by respiratory syncytial virus." Presented at RSV 2003 Symposium, Stone Mountain, GA, US|USA. (January 2003)

"Inhibition of epithelial sodium transport by respiratory syncytial virus.." Presented at European Respiratory Society Research Seminar: Current perspectives in epithelial cell injury and repair, Paris, FR|FRA. (January 2003)

"Mechanisms of up-regulation of epithelial sodium channel activity and fluid clearance in mouse lung by TNF-alpha." Presented at Experimental Biology, Washington, DC, US|USA. (January 2004)

"Respiratory syncytial virus inhibits alveolar fluid clearance by inducing release of de novo-synthesized UTP." Presented at Experimental Biology, Washington, DC, US|USA. (January 2004)

"Alterations in alveolar type II cell ion transport during Mycoplasma infection." Presented at 100th International Conference of the American Thoracic Society, Orlando, FL, US|USA. (January 2004)

"Effects of inhibitors of de novo pyrimidine synthesis on respiratory syncytial virus-induced inhibition of alveolar fluid clearance.." Presented at European Respiratory Society Annual Congress, Glasgow. (January 2004)

"Inhibition of epithelial sodium transport by respiratory syncytial virus.." Presented at NIAID, National Institutes of Health, Bethesda, MD. (January 2004)

"Inhibition of epithelial sodium transport by respiratory syncytial virus." Davis, CA. (January 2004)

"Inhibition of epithelial sodium transport by respiratory syncytial virus." Columbus, OH. (January 2005)

"Reactive oxygen and nitrogen species alter alveolar type II cell ion transport during Mycoplasma infection.." Presented at 101st International Conference of the American Thoracic Society, San Diego, CA, US|USA. (January 2005)

"Respiratory syncytial virus-induced inhibition of alveolar fluid clearance is insensitive to beta-agonists." Presented at RSV 2005, Oxford. (January 2005)

"Respiratory syncytial virus-induced inhibition of alveolar fluid clearance is insensitive to beta-agonists." Presented at Experimental Biology, San Diego, CA, US|USA. (January 2005)

"Aerobic exercise attenuates airway hyperreactivity and alters T cell responses in asthmatics." Presented at 102nd International Conference of the American Thoracic Society, San Diego, CA, US|USA. (January 2006)

"Beta agonist insensitivity of alveolar fluid clearance in RSV-infected mice is pyrimidine-mediated." Presented at 102nd International Conference of the American Thoracic Society, San Diego, CA, US|USA. (January 2006)

"Nucleotides as "metabokines" in respiratory syncytial virus infection." Columbus, OH. (January 2006)

"How insensitive! Cruel indifference to beta-agonists after RSV infection." Columbus, OH. (January 2006)

"How insensitive! Cruel indifference to beta-agonists after RSV infection." Columbus, OH. (January 2006)

"Respiratory syncytial virus strain A2 induces airway insensitivity to beta-adrenergic agonists in BALB/c mice." Presented at RSV 2007, Marco Island, FL, US|USA. (January 2007)

"Alveolar fluid clearance studies in BALB/c mice." Raleigh, NC, US|USA. (January 2007)

"PTEN inhibition protects the lung against oleic acid-induced acute lung injury in mice." Presented at 104th International Conference of the American Thoracic Society, Toronto, CA|CAN. (January 2008)

"Influenza A virus inhibits alveolar fluid clearance in BALB/c mice." Presented at 104th International Conference of the American Thoracic Society, Toronto, CA|CAN. (January 2008)

"Effects of positive end-expiratory pressure on alveolar fluid clearance rate and response to beta-agonists in mice." Presented at 104th International Conference of the American Thoracic Society, Toronto, CA|CAN. (January 2008)

"Aerosolized nucleotide synthesis inhibitors for treatment of influenza." Presented at 9th Annual Merck-Merial NIH Veterinary Scholars Symposium, . (January 2009)

"Building on the SERCA." Presented at National Advisory Research Resources Council, Bethesda, MD, US|USA. (January 2009)

"Dysregulation of glucocorticoid receptor (GR) signaling by respiratory syncytial virus." Presented at Jensen Symposium on Nuclear Receptors, Cincinnati, OH, US|USA. (January 2009)

"Effect of influenza A virus infection on murine alveolar type II cell nucleotide metabolism." Presented at 9th Annual Merck-Merial NIH Veterinary Scholars Symposium, . (January 2009)

"Nucleotide synthesis inhibitor therapy for hypoxemia in influenza infection." Presented at Great Lakes Regional Center of Excellence in Biodefense Annual Meeting, Chicago, IL, US|USA. (January 2009)

"Insensitivity to beta-agonists following RSV infection." Columbus, OH. (October 2009)

"Aerosolized nucleotide synthesis inhibitors for treatment of influenza." Presented at 10th Annual Merial-NIH National Veterinary Scholars Symposium, . (January 2010)

"Influenza A virus (H1N1) infection results in ARDS-like disease in mice." Presented at 106th International Conference of the American Thoracic Society, New Orleans, LA, US|USA. (January 2010)

"Respiratory syncytial virus induces airway insensitivity to beta-agonists in BALB/c mice." Presented at Experimental Biology, Anaheim, CA, US|USA. (January 2010)

"Nucleotide synthesis inhibitor therapy for hypoxemia in influenza infection." Presented at NIAID Regional Centers of Excellence in Biodefense Annual National Meeting, Las Vegas, NV, US|USA. (January 2010)

"Nucleotide synthesis inhibitor therapy for hypoxemia in influenza infection." Chicago, IL. (January 2010)

"Nucleotide signaling as a therapeutic target for ARDS secondary to influenza." . (January 2010)

"Aerosolized nucleotide synthesis inhibitors as therapeutics for influenza A virus infection in a murine model." Presented at Influenza: Translating basic insights, Washington, DC, US|USA. (January 2010)

"Aerosolized nucleotide synthesis inhibitor therapy for influenza." Presented at Great Lakes Regional Center of Excellence in Biodefense Annual Meeting, . (January 2010)

"Influenza A virus (H1N1) infection results in ARDS-like disease in mice." Presented at 61st Annual ACVP Meeting, . (January 2010)

"Characterization of ARDS-like disease in mice with influenza A virus (H1N1) infection in accordance with human criteria." Presented at Influenza: Translating Basic Insights, Washington, DC, US|USA. (January 2010)

"ARDS-like alterations of pulmonary function in Influenza A virus (H1N1)-infected mice." Presented at OPS Annual Meeting, Cincinnati, OH. (January 2010)

"Effect of H1N1 influenza virus (A/PR/8) on lung function in BALB/c mice." Presented at 10th Annual Merial-NIH National Veterinary Scholars Symposium, . (January 2010)

"The TNF-derived TIP peptide reduces lung dysfunction in experimental influenza A virus infection." Presented at European Respiratory Society Annual Congress, Amsterdam, NL|NLD. (January 2011)

"Effects of influenza on murine lung function – implications for pathogenesis and treatment." Columbus, OH. (January 2011)

"Effects of DF508 CFTR heterozygosity on influenza pathogenesis." Columbus, OH. (January 2011)

"Development of pulmonary function tests for mice with influenza." Presented at Pulmonary Conference, Columbus, OH. (January 2011)

"Defining Acute Respiratory Distress Syndrome (ARDS) in mice infected with influenza A (H1N1)." Columbus, OH. (January 2011)

"Aerosolized nucleotide synthesis inhibitors as therapeutics for influenza A virus infection in a murine model." Presented at 107th International Conference of the American Thoracic Society, Denver, CO, US|USA. (January 2011)

"Aerosolized nucleotide synthesis inhibitor therapy for influenza." Presented at Great Lakes Regional Center of Excellence in Biodefense Annual Meeting., Chicago, IL. (January 2011)

"A1-adenosine receptors as therapeutic targets in influenza." Columbus, OH. (January 2011)

"Treatment of influenza virus-mediated lung injury: Blocking the A1-adenosine receptor." Presented at TechConnect World 2011, Boston, MA, US|USA. (January 2011)

"Important role for protein kinase-Calpha in combined pneumolysin/influenza A virus-induced pulmonary endothelial hyperpermeability." Presented at 24th International Conference on Antiviral Research, Sofia. (January 2011)

"Role of CD73 in pathogenesis of influenza A (H1N1) infection in mice." Presented at 107th International Conference of the American Thoracic Society, Denver, CO, US|USA. (January 2011)

 

Professional Activities

2001 - present Veterans' Administration.
2003 - present Wellcome Trust.
2007 - present Inspire Pharmaceuticals.
2008 - present Study Section. American Heart Association. Pittsburgh, PA.
2008 - present Cystic Fibrosis Foundation (UAB Training Grant Program).
2009 - present Study Section. American Heart Association. Tampa, FL.
2009 - present UK Medical Research Council.
2009 - present Israel Science Foundation.
2011 - present Respiratory Cell and Molecular Biology Section Program Committee. American Thoracic Society.