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Amy Lovett-Racke, PhD


460 W 12th Ave
Columbus, OH 43210

Phone: (614) 688-5647

Email: lovett-racke.1@osu.edu

 

Current OSU Appointments

Professor, SBS-Microbial Infectn/Immunity

Professor, SBS-Neuroscience

 

Advising Narrative

AMANDA SELHORST

Amanda is currently a graduate student at Ohio Dominican University pursuing a Master’s degree in Physician Assistant Studies. She was in the OSU Biomedical Sciences undergraduate program and did an Honors Thesis in my laboratory. Amanda gave an oral presentation at the OSU Medical Center Research Day Program in 2015 and she received 2nd place in Biological Sciences for her presentation at the Denman Undergraduate Research Forum in 2014. She is co-first author on a manuscript in preparation that describes how vitamin D signaling in neurons may be critical for minimizing central nervous system inflammation and protecting individuals from multiple sclerosis.



NICHOLAS JARJOUR

Nicholas is currently a graduate student at Washington University in St. Louis, MO, seeking a PhD in Immunology. He was in the OSU Biomedical Sciences undergraduate program and did an Honors Thesis in my laboratory. Nicholas received Honorable Mention for his presentation at the Denman Undergraduate Research Forum in 2013. He also recognized with several awards during his time in my laboratory, including National Science Foundation Graduate Research Fellowship Honorable Mention (2013-2014), OSU Honors Collegium Distinguished Senior Award (2013), Sigma Xi Associate Member (2012), and Barry M. Goldwater Scholarship Honorable Mention (2011-2012).

Noteworthy Graduate Narrative

MARY SEVERIN

Mary will receive her PhD in Dec 2015. Some of her accomplishments are below.

-Awards and Honors

2015 American Association of Immunologists Trainee Abstract Award

2015 American Association for the Advancement of Science (AAAS)/ScienceProgram for Excellence in Science Sponsored Membership

2014 Center for Microbial Interface Biology Travel Grant

2014 Hayes Forum Honorable Mention

2013 Immunology Round Table Travel Award

2013 Procter and Gamble Best Student Speaker Award

2013 Biomedical Sciences Graduate Program Travel Award

2012 Edward J. Ray Travel Award for Scholarship and Service

-Leadership

2012-2015 Student Representative: Professional Development and Mentoring Committee, Department of Microbial Infection and Immunity, OSUMC

2012-2014 President: The Microbial Infection and Immunity Graduate Student Society

2012 Social Chair: SUCCESS Graduate Student Committee, The Summer Undergraduate Course Creating Excellence in Scientific Study, OSUMC

2012 Judge: Ohio State Science Day, “Future Physician Scientist Award”

2012 Oral Proctor: Edward F. Hayes Graduate Research Forum

-Publications

2015 Severin ME, Lee P, Liu Y, AJ Selhorst, MG Gormley, W. Pei, Y. Yang, Guerau-de-Arellano M, , Racke MK, and Lovett-Racke AE. MiRNAs Targeting TGFβ Signaling Underlie the Treg Defect in Multiple Sclerosis (Submitted to Annals of Neurology).

2014 Peine K, Guerau-de-Arellano M, Lee P, Kanthamneni N, Severin ME, Probst D, Peng H, Yang Y, Vangundy Z, Papenfuss T, Lovett-Racke AE, Bachelder E, and Ainslie K. Treatment of Experimental Autoimmune Encephalomyelitis by Co-Delivery of Disease Associated Peptide and Dexamethasone in Acetalated Dextran Microparticles. Mol Pharm11:828.

National and International Presentations

2015 American Association of Immunologists Annual Meeting. New Orleans, LA.

2014 12th International Congress of Neuroimmunology, Mainz, Germany.

2014 American Association of Immunologists Annual Meeting, Pittsburgh, PA.



PRISCILLA LEE

Priscilla will receive her PhD in Dec 2015. Some of her accomplishments are below.

-Awards and Honors

2015 Outstanding presentation award in The OSU Molecular Life Science Interdisciplinary Graduate Programs Symposium

2015 The American Association of Immunologists Trainee Abstract Award

2014 The American Association of Immunologists Trainee Poster Award

2014 Selected for an oral presentation in OSU Center of Microbial Interface Biology Symposium

2013 1st place in poster competition in The OSU Molecular Life Science Interdisciplinary Graduate Programs Symposium

2013 Selected to participate in the Edward Hayes Graduate Research Forum ‐ 1st Place in the poster competition for Biological Sciences

2012-2014 NIH CTSA TL1 Fellowship - Specialization in Biomedical Clinical and Translational Science, Center of Clinical Translational Science, OSU

2012 Selected to participate in the Edward Hayes Graduate Research Forum

-Publications

2015 Lee PW, Yang Y, Racke MK and Lovett-Racke A.E. Analysis of TGF-β1 and TGF-β3 as Regulators of Encephalitogenic Th17 Cells: Implications for Multiple Sclerosis. Brain Behav Immunity 46:44.

2015 Yang Y, Winger RC, Lee PW, Nuro-Gyina PK, Minc A, Larson M, Liu Y, Pei W, Rieser E, Racke MK, Lovett-Racke AE. Impact of suppressing retinoic acid-related receptor gamma t (ROR)γt in ameliorating central nervous system autoimmunity. Clin Exp Immunol. 179:108.

2014 Peine KJ. Guerau-de-Arellano M, Lee PW, Kanthamneni N, Severin M, Probst GD, Peng H, Yang Y, Vangundy Z, Papenfuss TL, Lovett-Racke AE, Bachelder EM, Ainslie KM. Treatment of experimental autoimmune encephalomyelitis by codelivery of disease associated peptide and dexamethasone in acetalated dextran microparticles. Mol Pharm. 11:828.

-National and International Presentations

2015 102th the American Association of Immunologists meeting (New Orleans, LA ).

2014 12th International Congress of Neuroimmunology (Mainz, Germany).

2014 101th the American Association of Immunologists (Pittsburg, PA).

2013 National Clinical and Translational Sciences Predoctoral Programs Meeting (Rochester, MN).

2012 11th International Congress of Neuroimmunology (Boston, MA).



DAVID HUSS, PHD

David is currently a Scientist II, running an independent laboratory at Biogen. Some of his accomplishments during graduate school are below.

-Awards and Honors

2010 Award winner for oral presentation at the OSU Molecular Life Sciences Interdisciplinary Graduate Program Symposium.

2009-2011 NIH TL1 Fellowship – Center for Clinical and Translational Science, OSU.

-Publications

2012 Peng H, M Guerau, VB Mehta, DJ Huss, TL Papenfuss, AE Lovett-Racke, and MK Racke. Dimethyl fumarate inhibits dendritic cell maturation via Nuclear Factor κB (NF-κB) and Extracellular Signal-related kinase 1 and 2 (ERK1/2) and Mitogen Stress activated kinase 1 (MSK1) signaling. J Biol Chem 10;287:28017.

2011 Huss DJ, RC Winger, Y Yang, M Guerau, MK Racke, AE Lovett Racke. TGF-β signaling via smad4 drives IL-10 production in effector Th1 cells and reduces host cell recruitment in EAE. Eur J Immunol 41:2987.

2010 Huss DJ, RC Winger, H Peng, Y Yang, MK Racke and AE. Lovett-Racke. TGF-β enhances effector Th1 cell activation but promotes self-regulation via IL-10. J Immunol 184:5628.

2010 Peng H. and DJ Huss. A novel role for Kv1.3 blockers: protecting neural progenitor cells from a hostile inflammatory environment. J Neurosci 30(32):10609.

2009 Yang Y, J Weiner, Y Liu, AJ Smith, DJ Huss, R Winger, H Peng, PD Cravens, MK Racke and AE Lovett-Racke. T-bet is essential for encephalitogenicity of both Th1 and Th17 cells. J Exp Med 206:1549.

-National and International Presentations

2010 10th International Congress of Neuroimmunology: Barcelona, Spain.



ALAN J. SMITH, MD/PHD

-Awards and Honors

2010 NIH TL1 Fellowship – Center for Clinical and Translational Science, The Ohio State University, Columbus, OH

2009 MD/PhD Scientific Achievement Travel Award, The Ohio State University, Columbus, OH

-Publications

2011 Smith AJ, Liu Y, Peng H, Beers R, Racke MK, Lovett-Racke AE. Comparison of a Classical Th1 Bacteria Versus a Th17 Bacteria as Adjuvant in the Induction of Experimental Autoimmune Encephalomyelitis. J Neuroimmunol 237:33-8.

2009 Yang Y, Weiner J, Liu Y, Smith AJ, Huss DJ, Winger R, Peng H, Cravens PD, Racke MK, Lovett-Racke AE. T-bet is Essential for Encephalitogenicity of Both Th1 and Th17 Cells. J Exp Med 206:1549.

-National and International Conference Presentations

2008 9th International Congress of Neuroimmunology, Fort Worth, TX.



ANNE ROCCHINI GOCKE, PHD

Anne is currently an Assistant Professor at John Hopkins University. Some of her accomplishments during graduate school are below.

-National and International Presentations

2006 8th International Congress of Neuroimmunology, Nagoya, Japan.

2006 Cold Spring Harbor Conference, Cold Springs, NY.

2004 7th International Congress of Neuroimmunology, Venice, Italy.

-Publications

2011 Ghoreschi K, Weigert C, Deng C, Bruck J, Hussain RZ, Gocke AR, Respa A, Valtcheva N, Feil S, Feil R, Rupec RA, Lovett-Racke AE, Dringen R, Racke MK and Rocken M. Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells. J Exp Med 208:2291.

2010 Hu W, Nessler S, Hemmer B, Eagar TN, Kane LP, Leliveld SR, Müller-Schiffmann A, Gocke AR, Lovett-Racke A, Ben L, Hussain R, Breil A, Elliott JL, Puthaparthi K, Cravens PD, Singh MP, Petsch B, Stitz L, Racke MK, Korth C and Stüve O. Pharmacological PrP-silencing accelerates CNS autoimmune disease via TCR signaling. Brain 133:375.

2010 Yang Y, Liu Y, Wei P, Peng H, Winger R, Hussain RZ, Ben L., Cravens PD, Gocke AR, Puttaparthi K, Racke MK, McTigue DM and Lovett-Racke AE. Silencing Nogo-A promotes functional recovery in demyelinating disease. Ann Neurol 67:498.

2009 Gocke AR, Hussain RZ. Ben L, Drew PD, Lovett-Racke AE and Racke MK. Transcription modulation of the immune response by PPARα agonists amerliorates autoimmune encephomyelitis. J Immunol 182:4479.

2008 Yang Y, Gocke AR, Lovett-Racke AE, Drew PD and Racke MK. PPAR regulation of the immune response and autoimmune encephalomyelitis. PPAR Research 2008:546753.

2007 Gocke AR, Northrop SC, Ben L, Hussain RZ, Cravens PD, Racke MK and Lovett-Racke AE. T-bet regulates the fate of TH1 and TH17 lymphocytes in autoimmunity. J Immunol 178:1341.

2006 Racke MK, Gocke AR, Muir M, Diab A, Drew PD and Lovett-Racke AE. Nuclear receptors and autoimmune disease: The potential of PPAR agonists to treat multiple sclerosis. J Nutrition 136:700.

2005 Lovett-Racke AE, Cravens PD, Gocke AR, Racke MK and Stuve O. Therapeutic potential of small interfering RNA for central nervous system diseases. Arch Neurol 62:1810.

2004 Lovett-Racke AE, Rocchini AE, Choy J, Northrop SC, Hussain RZ, Sikder D and Racke MK. Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes. Immunity 21:719.

Research Funding

I have been continuously funded since 1999, the year in which I became faculty at UT Southwestern. Since joining the OSU faculty in 2006, I have been the principal investigator on 7 grants, 3 funded by the NIH, 3 funded by the National Multiple Sclerosis Society and one funded by the Strategic Pharma-Academic Research Consortium. In addition, I have been co-investigator on 8 additional grants. Thus, I have been able to contribute significantly to MS research, and I have also be able to provide significant support to my own salary, including some years in which I was supported 100% by grants.

Academic Advising

I have had the opportunity to work with numerous young people in various stages of their education and career, and advise them on opportunities and assist them with pursuing their goals. As a faculty member in three graduate programs, graduate students from all of these programs have performed rotations in my laboratory and I have assisted them in identifying laboratories for their dissertation research. Since there are relatively few immunologists in the College of Medicine, I have also had the opportunity to advise several students in other laboratories on their research projects that has been very successful for broadening opportunities for students, as well as forging collaborations between laboratories. I also assist graduate students with preparation for their Oral Candidacy Exam. I have developed core concepts to assist students with fundamental skills necessary to be successful during oral exams. Several individuals have also joined my laboratory for the purpose of gaining insight into medical research and academic medicine, enabling them to make well-informed decisions on pursuing a career in medicine and/or research. As a working mother of 6 children, I have also been a source for graduate students with children or planning to have children to discuss issues about the feasibility of have a research career and managing a demanding family life. In addition to one-on-one conversations with students, I have participated in panel discussions on managing personal and professional lives.

Academic Advising

2011 Priscilla Lee, The Ohio State University. Graduated 0. Defining the Minimal Signals Required to Generate Encephalitogenic T Cells
2011 Mary Severin, The Ohio State University. Graduated 0. MicroRNAs Underlie the Treg Defect in Multiple Sclerosis
2015 Vikas Pulluru, The Ohio State University. Graduated 0.
2015 Giancarlo Valiente, The Ohio State University. Graduated 0.
2015 Matthew Xin, The Ohio State University. Graduated 0.
2015 Phyllis Donkor, The Ohio State University. Graduated 0.
2015 Varun Shah, The Ohio State University. Graduated 0.
2009 - 2010 Fatemeh Talebian, The Ohio State University. Graduated 2012. CD200-CD200R Interaction in Tumor Immunity
2009 - 2010 Ekaterina Karelina, The Ohio State University. Graduated 2010. Mechanisms of Social Neuroprotection after Cerebral Ischemia
2009 - 2010 Naveen Kanthamneni, The Ohio State University. Graduated 2012. Development of Immunosupressant and Peptide Loaded Microparticles as Tolerogenic Vaccines for Treatment of Autoimmune Diseases
2010 W. Hans, The Ohio State University. Graduated 2015. Improving Oncolytic Viral Therapy for Brain Tumors
2010 Amanda Roloson, The Ohio State University. Graduated 0.
2006 - 2011 Yuhong Yang, The Ohio State University. Graduated 0.
2010 - 2011 Ashley Fenn, The Ohio State University. Graduated 2014. Mechanisms and Consequences of Microglial Priming and Dysregulated M2a Responses with Age and Central Nervous System Injury
2011 Christie McCracken, The Ohio State University. Graduated 2015. Toxicity of Food-Relevant Nanoparticles in Intestinal Epithelial Models
2010 - 2012 Fatemeh Talebian, The Ohio State University. Graduated 2012. CD200-CD200R Interaction in Tumor Immunity
2011 - 2012 Sara McMaken, The Ohio State University. Graduated 0.
2011 - 2013 Kevin Peine, The Ohio State University. Graduated 2014. Formulation of Particulate-based Immunomodulatory Therapeutics for the Treatment of Diseases
2012 - 2013 Bryan Brautigam, The Ohio State University. Graduated 2013. Examining the Regulation of Inflammation through CD200 and CD200R Following Spinal Cord Injury
2012 - 2013 Nicholas Jarjour, The Ohio State University. Graduated 2013.
2012 - 2013 Matthew Koerbel, The Ohio State University. Graduated 2014.
2011 - 2014 Ashley Fenn, The Ohio State University. Graduated 2014. Mechanisms and Consequences of Microglial Priming and Dysregulated M2a Responses with Age and Central Nervous System Injury
2013 - 2014 Ying-Chin Wang, The Ohio State University. Graduated 2014. Using Red Blood Cells in Microbial Fuel Cell Catholyte Solution to Improve Electricity Generation
2013 - 2014 Kevin Peine, The Ohio State University. Graduated 2014. Formulation of Particulate-based Immunomodulatory Therapeutics for the Treatment of Diseases
2013 - 2014 Patrick Nuro-Gyina, The Ohio State University. Graduated 0.
2014 Christina Sabin, The Ohio State University. Graduated 0.
2014 Patrick Nuro-Gyina, The Ohio State University. Graduated 0.
2013 - 2015 Amanda Selhorst, The Ohio State University. Graduated 2015. Defining the Role of Vitamin D in Multiple Sclerosis
2014 - 2015 Varun Shah, The Ohio State University. Graduated 0.
 

Chapters in Books

Arredondo LR, Lovett-Racke AE and Racke MK. "Experimental Autoimmune Encephalomyelitis." In Multiple Sclerosis: Immunology, Pathology and Pathophysiology. Edited by RM Herndon. 79-103. New York: Demos Medical Publishing, Inc, January 2003.

Lovett-Racke AE and Racke MK. "The Role of Growth Factors in Experimental Autoimmune Encephalomyelitis." In Experimental Models of Multiple Sclerosis. Edited by E Lavi and CS Constantinescu. 343-361. New York: Springer Science Business Media, Inc, January 2005.

Racke MK, Ratts RB, Stuart RW, Deng C and Lovett-Racke AE. "The Role of Costimulation in Experimental Autoimmune Encephalomyelitis." In Experimental Models of Multiple Sclerosis. Edited by E Lavi and CS Constantinescu. 471-490. New York: Springer Science Business Media, Inc, January 2005.

Lovett-Racke AE, Gocke AR and Cravens PD. "The Basics of Cellular and Molecular Immunology." In Neuroimmunology in Clinical Practice. Edited by B Kalman and TH Brannagan. -. Hoboken: Wiley Blackwell Publishing, January 2007.

Lovett-Racke AE. "Therapeutic Potential of Small Interfering RNA for Brain Diseases." In Therapeutic Ribonucleic Acids in Brain Tumors. Edited by VA Erdmann, G Reifenberger and J Barciszewski. 275-296. New York: Springer, January 2009.

Yang Y, Lovett-Racke AE and Racke MK. "Role of IL-12/IL-23 in the Pathogenesis of Multiple Sclerosis." In Neuroinflammation. -. Amsterdam: Elsevier Science BV, June 2011.

Lovett-Racke AE and Racke MK. "T-bet as a Key Transcription Factor in Autoimmune Inflammatory Demyelination." In Multiple Sclerosis Immunology - A Foundation for Current and Future Treatments. -. New York: Springer, October 2013.

 

Degrees

1987 A.A.S., Texas A&M University

1993 B.F.A., The University of Texas Health Science Center at Houston

 

Editorial Activities

2004 - present Journal of Leukocyte Biology
2005 - present Acta Pharmacologica Sinica
2005 - present Journal of Neuroimmunology
2007 - present Proceedings of the National Academy of Science
2007 Arthritis and Rheumatism
2008 - present PPAR Research
2008 - present Journal of Immunology
2008 - present Immunobiology
2009 - present Brain, Behavior and Immunity
2009 - present European Journal of Immunology
2010 - present Frontiers in Neurology: Multiple Sclerosis and Neuroimmunology
2010 - present Journal of Neuroimmunology
2010 - present Annals of Neurology
2011 - present Brain
2011 Nature
2011 - 2015 Journal of Immunology
2012 - present PLoS One
2014 - present Brain, Behavior and Immunity
2014 - present Clinical Immunology
2014 Frontiers in Immunology
 

Honors

1993 - 1995 Intramural Research Training Award. National Institutes of Neurological Disorders and Stroke.
1995 - 1997 Lucille P. Markey Special Emphasis Pathway in Human Pathobiology. Lucille P. Markey Foundation.
2004 - 2009 Harry Weaver Neuroscience Scholar. National Multiple Sclerosis Society.
2010 - present Excellence in Teaching. College of Medicine Med I/II Integrated Pathway Program.
2013 College of Medicine Distinguished Educator Award. OSU College of Medicine.
2014 - present Multiple Sclerosis Research Hall of Fame. National Multiple Sclerosis Society.
 

Journal Articles

Fermin CD, Lovett AE, Igarashi M and Dunner K. "Immunohistochemistry and histochemistry of the inner ear gelatinous membranes and statoconia of the chick (Gallus domesticus).." Acta Anatomica. Vol. 138, no. 1. (January 1990.): 75-83.

Fermin,C,D; LOVETT,A,E; Igarashi,M; Dunner,K. "Immunochemistry and Histochemistry of the Inner-Ear Gelatinous Membranes and Statoconia of the Chick (Gallus-Domesticus)." ACTA ANATOMICA. Vol. 138, no. 1. (May 1990.): 75-83.

Wolinsky JS, McCarthy M, Allen-Canady O, Moore WT, Jin R, Cao SN, Lovett-AE and Simmons D. "Monoclonal antibody-defined map of expressed rubella virus protein domains." Journal of Virology. Vol. 65, (January 1991.): 3986-3994.

Wolinsky,J,S; McCarthy,M; ALLENCANNADY,O; Moore,W,T; Jin,R; Cao,S,N; Lovett,A; Simmons,D. "MONOCLONAL ANTIBODY-DEFINED EPITOPE MAP OF EXPRESSED RUBELLA-VIRUS PROTEIN DOMAINS." JOURNAL OF VIROLOGY. Vol. 65, no. 8. (August 1991.): 3986-3994.

Wolinsky JS, Sukholutsky E, Moore WT, Lovett AE, McCarthy M and Adame B. "An antibody and synthetic peptide defined rubella virus E1 glycoprotein neutralization domain." Journal of Virology. Vol. 67, (January 1993.): 961-968.

McCarthy M, Lovett AE, Kerman RH, Overstreet A and Wolinsky JS. "Immunodominant T cell epitopes of rubella virus structural proteins and synthetic peptides." Journal of Virology. Vol. 67, (January 1993.): 673-681.

Lovett AE, Hahn CS, Rice CM, Frey TK, Wolinsky JS. "Rubella virus-specific cytotoxic T-lymphocyte responses: identification of the capsid as a target of major histocompatibility complex class I-restricted lysis and definition of two epitopes." Journal of Virology. Vol. 67, no. 10. (January 1993.): 5849-5858.

Wolinsky,J,S; SUKHOLUTSKY,E; Moore,W,T; Lovett,A; McCarthy,M; ADAME,B. "AN ANTIBODY PEPTIDE-DEFINED AND SYNTHETIC PEPTIDE-DEFINED RUBELLA-VIRUS E1 GLYCOPROTEIN NEUTRALIZATION DOMAIN." JOURNAL OF VIROLOGY. Vol. 67, no. 2. (February 1993.): 961-968.

McCarthy,M; Lovett,A; Kerman,R,H; OVERSTREET,A; Wolinsky,J,S. "IMMUNODOMINANT T-CELL EPITOPES OF RUBELLA-VIRUS STRUCTURAL PROTEINS DEFINED BY SYNTHETIC PEPTIDES." JOURNAL OF VIROLOGY. Vol. 67, no. 2. (February 1993.): 673-681.

LOVETT,A,E; McCarthy,M; Wolinsky,J,S. "MAPPING CELL-MEDIATED IMMUNODOMINANT DOMAINS OF THE RUBELLA-VIRUS STRUCTURAL PROTEINS USING RECOMBINANT PROTEINS AND SYNTHETIC PEPTIDES." JOURNAL OF GENERAL VIROLOGY. Vol. 74, (March 1993.): 445-452.

LOVETT,A,E; Hahn,C,S; Rice,C,M; Frey,T,K; Wolinsky,J,S. "RUBELLA VIRUS-SPECIFIC CYTOTOXIC T-LYMPHOCYTE RESPONSES - IDENTIFICATION OF THE CAPSID AS A TARGET OF MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I-RESTRICTED LYSIS AND DEFINITION OF 2 EPITOPES." JOURNAL OF VIROLOGY. Vol. 67, no. 10. (October 1993.): 5849-5858.

Lovett AE, McCarthy M and Wolinsky JS. "Mapping cell-mediated immunodominant domains of the rubella virus structural proteins using recombinant proteins and synthetic peptides.." The Journal of General Virology. Vol. 74 ( Pt 3), (January 1993.): 445-452.

Lovett-Racke AE, Martin R, McFarland HF, Racke MK and Utz, U. "Longitudinal study of myelin basic protein-specific T-cell receptors during the course of multiple sclerosis.." Journal of Neuroimmunology. Vol. 78, no. 1-2. (January 1997.): 162-71.

Lovett-Racke AE, Bittner P, Cross AH, Carlino JA and Racke MK. "Regulation of experimental autoimmune encephalomyelitis with insulin-like growth factor (IGF-1) and IGF-1/IGF-binding protein-3 complex (IGF-1/IGFBP3).." Journal of Clinical Investigation. Vol. 101, no. 8. (January 1998.): 1797-1804.

Begolka,W,S; Miller,S,D; Segal,B,M; Racke,M,K; Lovett-Racke,A,E. "Antigen-driven regulation of experimental autoimmune encephalomyelitis - Discussion." RESEARCH IN IMMUNOLOGY. Vol. 149, no. 9. (November 1998.): 842-843.

Racke MK and Lovett-Racke AE. "Bystander suppression in experimental autoimmune encephalomyelitis: where and how does it occur?." Research in Immunology. Vol. 149, (January 1998.): 820-827.

Lovett-Racke AE, Trotter JL, Lauber J, Perrin PJ, June CH and Racke MK. "Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells.." Journal of Clinical Investigation. Vol. 101, no. 4. (January 1998.): 725-730.

Begolka,W,S; Miller,S,D; Segal,B,M; Racke,M,K; Lovett-Racke,A,E. "Antigen-driven regulation of experimental autoimmune encephalomyelitis - Discussion." RESEARCH IN IMMUNOLOGY. Vol. 149, no. 9. (November 1998.): 842-843.

Perrin PJ, Lovett-Racke AE, Phillips SM and Racke MK. Histology and Histopathology. Vol. 14, (January 1999.): 1269-1276.

Ratts RB, Arredondo LR, Bittner P, Perrin PJ, Lovett-Racke AE and Racke MK. "The role of CTLA-4 in tolerance induction and T cell differentiation in experimental autoimmune encephalomyelitis: i.p. antigen administration.." International Immunology. Vol. 11, no. 12. (January 1999.): 1881-8.

Perrin,P,J; Lovett-Racke,A; Phillips,S,M; Racke,M,K. "Differential requirements of naive and memory T cells for CD28 costimulation in autoimmune pathogenesis." HISTOLOGY AND HISTOPATHOLOGY. Vol. 14, no. 4. (October 1999.): 1269-1276.

Ratts RB, Arredondo LR, Bittner P, Perrin PJ, Lovett-Racke AE and Racke MK. "The role of CTLA-4 in tolerance induction and antigen administration cell differentiation in experimental autoimmune encephalomyelitis: i. v. antigen administration.." International Immunology. Vol. 11, no. 12. (January 1999.): 1889-1896.

Racke MK, Ratts RB, Arredondo L, Perrin PJ and Lovett-Racke AE. Journal of Neuroimmunology. Vol. 107, (January 2000.): 205-215.

Lovett-Racke AE, Smith ME, Arredondo LR, Bittner PS, Ratts RB, Shive CL, Forsthuber TG and Racke MK. "Developmentally regulated gene expression of Th2 cytokines in the brain.." Brain Research. Vol. 870, no. 1-2. (January 2000.): 27-35.

Racke,M,K; Ratts,R,B; Arredondo,L; Perrin,P,J; Lovett-Racke,A. "The role of costimulation in autoimmune demyelination." JOURNAL OF NEUROIMMUNOLOGY. Vol. 107, no. 2. (July 2000.): 205-215.

Peters TR, Bodine DM, McDonagh KT, Lovett-Racke AE, McFarland HF, McFarlin DE, Nienhuis AW and Racke MK. "Retrovirus mediated gene transfer of the self antigen MBP into the bone marrow of B10.PL mice does not confer resistance to experimental autoimmune encephalomyelitis." Journal of Neuroimmunology. Vol. 103, (January 2000.): 51-62.

Arredondo LR, Deng C, Ratts RB, Lovett-Racke AE, Holtzman DM and Racke MK. "Role of nerve growth factor in experimental autoimmune encephalomyelitis." European Journal of Immunology. Vol. 31, no. 2. (January 2001.): 625-633.

Frohman EM, Monson NL, Lovett-Racke AE and Racke MK. Journal of Clinical Immunology. Vol. 21, (January 2001.): 61-73.

Frohman,E,M; Monson,N,L; Lovett-Racke,A,E; Racke,M,K. "Autonomic regulation of neuroimmunological responses: Implications for multiple sclerosis." JOURNAL OF CLINICAL IMMUNOLOGY. Vol. 21, no. 2. (March 2001.): 61-73.

Racke MK, Lovett-Racke AE, Karandikar NJ, Wilson B and Monson NL. "Myelin-reactive T cells and their regulation in multiple sclerosis." NeuroScience News. Vol. 4, (January 2001.): 29-38.

Deng C, Minguela A, Hussain RZ, Lovett-Racke AE, Radu C, Ward ES and Racke MK. "Expression of the tyrosine phosphatase SRC homology 2 domain-containing protein tyrosine phosphatase 1 determines T cell activation threshold and severity of experimental autoimmune encephalomyelitis.." Journal of Immunology. Vol. 168, no. 9. (January 2002.): 4511-8.

Lovett-Racke AE and Racke MK. "Retinoic acid promotes the development of Th2-like human myelin basic protein-reactive T cells." Cellular Immunology. Vol. 215, no. 1. (January 2002.): 54-60.

Karandikar NJ, Crawford MP; Yan X, Ratts,RB, Brenchley JM, Ambrozak DR, Lovett-Racke AE, Frohman EM, Stastny P, Douek DC, Koup RA and Racke MK. "Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis." Journal of Clinical Investigation. Vol. 109, no. 5. (January 2002.): 641-9.

Diab A, Deng C, Smith JD, Hussain RZ, Phanavanh B, Lovett-Racke AE, Drew PD and Racke MK. "Peroxisome proliferator-activated receptor-gamma agonist 12-deoxy-delta (12,14)-prostaglandin J2 ameliorates experimental autoimmune encephalomyelitis." Journal of Immunology. Vol. 168, no. 5. (January 2002.): 2508-2515.

Deng C, Wu Bo, Yang H, Hussain RZ, Lovett-Racke AE, Christadoss P and Racke MK. "Decreased expression of Src homology 2 domain-containing protein tyrosine phosphatase 1 reduces T cell activation threshold but not the severity of experimental autoimmune myasthenia gravis.." Journal of neuroimmunology. Vol. 138, no. 1-2. (January 2003.): 76-82.

Diab A, Hussain RZ, Lovett-Racke AE, Chavis JA, Drew PD and Racke MK. "Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis.." Journal of Neuroimmunology. Vol. 148, no. 1-2. (January 2004.): 116-126.

Ratts,R; Lovett-Racke,A; Karandikar,N; Racke,M. "Characterization of chronically stimulated T cells in humans." JOURNAL OF NEUROIMMUNOLOGY. Vol. 154, no. 1-2. (September 2004.): 216-216.

Ratts,R; Lovett-Racke,A; Karandikar,N; Racke,M. "Characterization of chronically stimulated T cells in humans." JOURNAL OF NEUROIMMUNOLOGY. Vol. 154, no. 1-2. (September 2004.): 216-216.

Lovett-Racke AE, Rocchini AE, Choy J, Northrop SC, Hussain RZ, Ratts RB, Sikder D and Racke MK. "Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes.." Immunity. Vol. 21, no. 5. (January 2004.): 719-731.

Lovett-Racke AE, Hussain RZ, Northrop S, Choy J, Rocchini A, Matthes L, Chavis JA, Diab A, Drew PD and Racke MK. "Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease.." Journal of Immunology. Vol. 172, no. 9. (January 2004.): 5790-5798.

Racke MK, Hu W and Lovett-Racke AE. Trends in Immunology. Vol. 26, (January 2005.): 289-291.

Muir MT, Lovett-Racke AE and Racke MK. Expert Review in Clinical Immunology. Vol. 1, (January 2005.): 345-355.

Frohman EM, Brannon K, Frohman TC, Giesser B, Langer-Gould A, Levalds C, Lovett-Racke AE, Treadaway K, Waubant E, Winslow H and Wuermser LA. "Part 1: Characterizing the disease process." Female Patient. Vol. 30, (January 2005.): 41-46.

Lovett-Racke,A,E; Cravens,P,D; Gocke,A,R; Racke,M,K; Stuve,O. "Therapeutic potential of small interfering RNA for central nervous system diseases." ARCHIVES OF NEUROLOGY. Vol. 62, no. 12. (December 2005.): 1810-1813.

Lovett-Racke,A,E; Cravens,P,D; Gocke,A,R; Racke,M,K; Stuve,O. "Therapeutic potential of small interfering RNA for central nervous system diseases." ARCHIVES OF NEUROLOGY. Vol. 62, no. 12. (December 2005.): 1810-1813.

Muir,Mark,T; Lovett-Racke,Amy,E; Racke,Michael,K. "Novel therapeutic strategies targeting the pathogenic T-cells in multiple sclerosis.." Expert review of clinical immunology. Vol. 1, no. 3. (September 2005.): 345-355.

Racke,M,K; Hu,W; Lovett-Racke,A,E. "PTX cruiser: driving autoimmunity via TLR4." TRENDS IN IMMUNOLOGY. Vol. 26, no. 6. (June 2005.): 289-291.

Lovett-Racke AE, Cravens PD, Gocke AR, Racke MK and Stuve O. Archives of Neurology. Vol. 62, (January 2005.): 1810-1813.

Frohman EM, Brannon K, Frohman TC, Giesser B, Langer-Gould A, Levalds C, Lovett-Racke AE, Treadaway K, Waubant E, Winslow H and Wuermser LA. "Part 2: Clinical manifestations and symptomatic treatment strategies." Female Patient. Vol. 30, (January 2005.): 46-50.

Lovett-Racke AE and Racke MK. Archives of Neurology. Vol. 63, (January 2006.): 810-811.

Hansen BS, Hussain RZ, Lovett-Racke AE, Thomas JA and Racke MK. "Multiple toll-like receptor agonists act as potent adjuvants in the induction of autoimmunity.." Journal of Neuroimmunology. Vol. 172, no. 1-2. (January 2006.): 94-103.

Ratts RB, Lovett-Racke AE, Choy J, Northrop SC, Hussain RZ, Karandikar NJ and Racke MK. "CD28-CD57+ T cells predominate in CD8 responses to glatiramer acetate.." Journal of Neuroimmunology. Vol. 178, no. 1-2. (January 2006.): 117-129.

Ratts RB, Karandikar NJ, Hussain RZ, Choy J, Northrop SC, Lovett-Racke AE and Racke MK. "Phenotypic characterization of autoreactive T cells in multiple sclerosis.." Journal of Neuroimmunology. Vol. 178, no. 1-2. (January 2006.): 100-110.

Lovett-Racke,Amy,E; Racke,Michael,K. "Epstein-Barr virus and multiple sclerosis." ARCHIVES OF NEUROLOGY. Vol. 63, no. 6. (June 2006.): 810-811.

Lovett-Racke,Amy,E; Racke,Michael,K. "Epstein-Barr virus and multiple sclerosis." ARCHIVES OF NEUROLOGY. Vol. 63, no. 6. (June 2006.): 810-811.

Racke,M,K; Gocke,A,R; Muir,M; Diab,A; Drew,P,D; Lovett-Racke,A,E. "Nuclear receptors and autoimmune disease: The potential of PPAR agonists to treat multiple sclerosis." JOURNAL OF NUTRITION. Vol. 136, no. 3. (March 2006.): 700-703.

Racke MK, Gocke AR, Muir M, Diab A, Drew PD and Lovett-Racke AE. "The potential of PPAR agonists to treat multiple sclerosis." Journal of Nutrition. Vol. 136, (January 2006.): 700-703.

Gocke AR, Cravens PD, Ben LH, Hussain RZ, Northrop SC, Racke MK and Lovett-Racke AE. "T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity.." Journal of Immunology. Vol. 178, no. 3. (January 2007.): 1341-1348.

Stuart R, Lovett-Racke AE, Frohman EM, Hawker K and Racke MK. "Genetic analysis of the exon 1 position 49 CD152 dimorphism in multiple sclerosis.." Journal of Neuroimmunology. Vol. 191, no. 1-2. (January 2007.): 45-50.

Yang Y, Ratts RB, Hussain RZ, Northrop SC, Ben LH, Lovett-Racke A and Racke MK. "CD28:B7 interaction is necessary for the protective effect of T cell vaccination in EAE.." European Journal of Immunology. Vol. 37, no. 7. (January 2007.): 2032-2042.

Stuve,Olaf; Marra,Christina,M; Cravens,Petra,D; Singh,Mahendra,P; Hu,Wei; Lovett-Racke,Amy; Monson,Nancy,L; Phillips,J,Theodore; Tervaert,Jan,WCohen; Nash,Richard,A; Hartung,Hans-Peter; Kieseier,Bernd,C; Racke,Michael,M; Frohman,Elliot,M; Hemmer,Bernhard. "Potential risk of progressive multifocal leukoencephalopathy with natalizumab therapy - Possible interventions." ARCHIVES OF NEUROLOGY. Vol. 64, no. 2. (February 2007.): 169-176.

Stuve O, Marra CM, Cravens PD, Singh MP, Hu W, Lovett-Racke AE, Monson NL, Phillips JT, Tervaert JW, Nash RA, Hartung HP, Kiesseier BC, Racke MK, Frohman EM and Hemmer B. Archives of Neurology. Vol. 64, (January 2007.): 169-176.

Novak JC, Lovett-Racke AE and Racke MK. Archives of Neurology. Vol. 65, (January 2008.): 1162-1165.

Yang,Yuhong; Gocke,Anne,R; Lovett-Racke,Amy; Drew,Paul,D; Racke,Michael,K. "PPAR Alpha Regulation of the Immune Response and Autoimmune Encephalomyelitis." PPAR RESEARCH. Vol. 2008, (January 2008.): 546753-.

Novak,John,C; Lovett-Racke,Amy,E; Racke,Michael,K. "Monoclonal antibody therapies and neurologic disorders." ARCHIVES OF NEUROLOGY. Vol. 65, no. 9. (September 2008.): 1162-1165.

Yang Y, Gocke AR, Lovett-Racke AE, Drew PD and Racke MK. PPAR Research. Vol. 2008, (January 2008.): 546753-.

Harp CT, Lovett-Racke AE, Racke MK, Frohman EM and Monson NL. "Impact of myelin-specific antigen presenting B cells on T cell activation in multiple sclerosis." Clinical Immunology. Vol. 128, (January 2008.): 382-391.

Yang Y, Weiner J, Liu Y, Smith AJ, Huss DJ, Winger R, Peng H, Cravens PD, Racke MK and Lovett-Racke AE. "T-bet is essential for encephalitogenicity of both TH1 and TH17 cells." Journal of Experimental Medicine. Vol. 206, no. 7. (January 2009.): 1549-1564.

Gocke AR, Hussain RZ, Yang Y, Peng H, Weiner J, Ben LH, Drew PD, Stuve O, Lovett-Racke AE and Racke MK. "Transcriptional modulation of the immune response by peroxisome proliferator-activated receptor-alpha agonists in autoimmune disease." Journal of Immunology. Vol. 182, (January 2009.): 4479-4487.

Racke MK, Lovett-Racke AE and Karandikar N.J. Neurology. (January 2009.): -.

Racke,M; Yang,Y; Liu,Y; Smith,A; Winger,R; Peng,H; Cravens,P; Lovett-Racke,A. "T-bet, not cytokine expression, determines T-cell encephalitogenicity." MULTIPLE SCLEROSIS JOURNAL. Vol. 15, no. 9. (September 2009.): S59-S60.

Racke,M; Yang,Y; Liu,Y; Smith,A; Winger,R; Peng,H; Cravens,P; Lovett-Racke,A. "T-bet, not cytokine expression, determines T-cell encephalitogenicity." MULTIPLE SCLEROSIS JOURNAL. Vol. 15, no. 9. (September 2009.): S59-S60.

Nessler,S; Hu,W; Hemmer,B; Eagar,T; Kane,L; Leliveld,R; Mueller-Schiffmann,A; Gocke,A; Lovett-Racke,A; Li-Hong,B; Hussain,R; BREIL,A; Elliott,J; Carlson,P; Cravens,P; Singh,M,P; Petsch,B; Stitz,L; Racke,M; Korth,C; Stueve,O. "Prion protein is a key regulator of T-cell activation, differentiation and survival." MULTIPLE SCLEROSIS JOURNAL. Vol. 15, no. 9. (September 2009.): S192-S192.

Nessler,S; Hu,W; Hemmer,B; Eagar,T; Kane,L; Leliveld,R; Mueller-Schiffmann,A; Gocke,A; Lovett-Racke,A; Li-Hong,B; Hussain,R; BREIL,A; Elliott,J; Carlson,P; Cravens,P; Singh,M,P; Petsch,B; Stitz,L; Racke,M; Korth,C; Stueve,O. "Prion protein is a key regulator of T-cell activation, differentiation and survival." MULTIPLE SCLEROSIS JOURNAL. Vol. 15, no. 9. (September 2009.): S192-S192.

Yang Y, Liu Y, Wei P, Peng H, Winger R, Hussain RZ, Ben LH, Cravens PD, Gocke AR, Puttaparthi K, Racke MK, McTigue DM and Lovett-Racke AE. "Silencing Nogo-A promotes functional recovery in demyelinating disease." Annals of Neurology. Vol. 67, no. 4. (January 2010.): 498-507.

Ghoreschi,Kamran; Keller,Christina; Deng,Caishu; Brueck,Juergen; Feil,Susanne; Feil,Robert; Lovett-Racke,Amy,E; Racke,Michael,K; Dringen,Ralf; Roecken,Martin. "Fumarates improve Psoriasis and Multiple Sclerosis by inducing type II dendritic cells." JOURNAL OF INVESTIGATIVE DERMATOLOGY. Vol. 130, (September 2010.): S11-S11.

Mireia,Guerau-de-Arellano; Kristen,Smith; Jakub,Godlewski; Caroline,Whitacre; Sean,Lawler; Amy,Lovett-Racke; Michael,Racke,K. "Mining the T cell miRNome for multiple sclerosis biomarkers." JOURNAL OF NEUROIMMUNOLOGY. Vol. 228, no. 1-2. (November 2010.): 65-65.

Mireia,Guerau-de-Arellano; Kristen,Smith; Jakub,Godlewski; Caroline,Whitacre; Sean,Lawler; Amy,Lovett-Racke; Michael,Racke,K. "Mining the T cell miRNome for multiple sclerosis biomarkers." JOURNAL OF NEUROIMMUNOLOGY. Vol. 228, no. 1-2. (November 2010.): 65-65.

David,Huss; Ryan,Winger; Peng Haiyan,H,Y; Yang Yuhong,Y,H; Michael,Racke; Amy,Lovett-Racke. "TGF-beta enhances Th1 cell activation yet reduces EAE disease course by promoting T cell self-regulation." JOURNAL OF NEUROIMMUNOLOGY. Vol. 228, no. 1-2. (November 2010.): 140-140.

David,Huss; Ryan,Winger; Peng Haiyan,H,Y; Yang Yuhong,Y,H; Michael,Racke; Amy,Lovett-Racke. "TGF-beta enhances Th1 cell activation yet reduces EAE disease course by promoting T cell self-regulation." JOURNAL OF NEUROIMMUNOLOGY. Vol. 228, no. 1-2. (November 2010.): 140-140.

Guerau-de-Arellano,Mireia; Lovett-Racke,Amy,E; Racke,Michael,K. "miRNAs in multiple sclerosis: Regulating the Regulators." JOURNAL OF NEUROIMMUNOLOGY. Vol. 229, no. 1-2. (December 2010.): 3-4.

Zein,Sima,S; Hu,Wei; Nessler,Stefan; Hemmer,Bernhard; Eagar,Todd; Kane,Lawrence,P; Leliveld,S,Rutger; Gocke,Anne,R; Lovett-Racke,Amy; Ben,Li,Hong; Hussain,Rehana; Elliot,Jeffrey; Puttaparthi,Krishna; Cravens,Petra,D; Petsch,Benjamin; Deming,Katherine; Stitz,Lothar; Racke,Michael,K; Korth,Carsten; Stuve,Olaf. "Pharmacological PrP-Silencing Accelerates CNS Autoimmune Disease Via TCR Signaling." NEUROLOGY. Vol. 74, no. 9. (March 2010.): A496-A496.

Kithcart,Aaron,P; Lovett-Racke,Amy; Stueve,Olaf; Monsoon,Nancy; Whitacre,Caroline; Racke,Michael. "Inflammatory Cytokines and Chemokines in the Cerebrospinal Fluid of Multiple Sclerosis Patients Following Administration of Natalizumab." NEUROLOGY. Vol. 74, no. 9. (March 2010.): A555-A555.

Kithcart,Aaron,P; Lovett-Racke,Amy; Stueve,Olaf; Monsoon,Nancy; Whitacre,Caroline; Racke,Michael. "Inflammatory Cytokines and Chemokines in the Cerebrospinal Fluid of Multiple Sclerosis Patients Following Administration of Natalizumab." NEUROLOGY. Vol. 74, no. 9. (March 2010.): A555-A555.

Kristen,Smith; Mireia,Guerau-de-Arellano; Arianna,Bottoni; Michael,Racke; Amy,Lovett-Racke; Caroline,Whitacre. "MicroRNAs modulate immune function in Multiple Sclerosis." JOURNAL OF NEUROIMMUNOLOGY. Vol. 228, no. 1-2. (November 2010.): 121-122.

Haiyan,Peng; Elif,Akyol; Mireia,Guerau; David,Pitt; Amy,Lovett-Racke; Michael,Racke. "The dual function of Dimethyl Fumarate in Multiple Sclerosis." JOURNAL OF NEUROIMMUNOLOGY. Vol. 228, no. 1-2. (November 2010.): 98-98.

Kristen,Smith; Mireia,Guerau-de-Arellano; Arianna,Bottoni; Michael,Racke; Amy,Lovett-Racke; Caroline,Whitacre. "MicroRNAs modulate immune function in Multiple Sclerosis." JOURNAL OF NEUROIMMUNOLOGY. Vol. 228, no. 1-2. (November 2010.): 121-122.

Yang,Yuhong; Lovett-Racke,Amy,E; Racke,Michael,K. "Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs." PPAR RESEARCH. Vol. 2010, (January 2010.): 104705-.

Racke MK, Lovett-Racke AE, Karandikar NJ.. "The mechanism of action of glatiramer acetate treatment in multiple sclerosis." NEUROLOGY. Vol. 74, no. Suppl 1. (January 2010.): S25-S30.

Huss,David,J; Winger,Ryan,C; Peng,Haiyan; Yang,Yuhong; Racke,Michael,K; Lovett-Racke,Amy,E. "TGF-beta Enhances Effector Th1 Cell Activation but Promotes Self-Regulation via IL-10." JOURNAL OF IMMUNOLOGY. Vol. 184, no. 10. (May 2010.): 5628-5636.

Hu,Wei; Nessler,Stefan; Hemmer,Bernhard; Eagar,Todd,N; Kane,Lawrence,P; Leliveld,S,Rutger; Mueller-Schiffmann,Andreas; Gocke,Anne,R; Lovett-Racke,Amy; Ben,Li-Hong; Hussain,Rehana,Z; Breil,Andreas; Elliott,Jeffrey,L; Puttaparthi,Krishna; Cravens,Petra,D; Singh,Mahendra,P; Petsch,Benjamin; Stitz,Lothar; Racke,Michael,K; Korth,Carsten; Stuve,Olaf. "Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling." BRAIN. Vol. 133, (February 2010.): 375-388.

Hu W, Nessler S, Hemmer B, Eagar TN, Kane LP, Leliveld SR, Müller-Schiffmann A, Gocke AR, Lovett-Racke A, Ben LH, Hussain R, Breil A, Elliott JL, Puthaparthi K, Cravens PD, Singh MP, Petsch B, Stitz L, Racke MK, Korth C and Stüve O. "Pharmacological PrP-silencing accelerates CNS autoimmune disease via TCR signaling." Brain. Vol. 133 (part 2), (January 2010.): 375-388.

Haiyan,Peng; Elif,Akyol; Mireia,Guerau; David,Pitt; Amy,Lovett-Racke; Michael,Racke. "The dual function of Dimethyl Fumarate in Multiple Sclerosis." JOURNAL OF NEUROIMMUNOLOGY. Vol. 228, no. 1-2. (November 2010.): 98-98.

Guerau-de-Arellano,Mireia; Lovett-Racke,Amy,E; Racke,Michael,K. "miRNAs in multiple sclerosis: Regulating the regulators." JOURNAL OF NEUROIMMUNOLOGY. Vol. 229, no. 1-2. (December 2010.): 3-4.

Harp,Christopher,T; Ireland,Sara; Davis,Laurie,S; Remington,Gina; Cassidy,Bonnie; Cravens,Petra,D; Stuve,Olaf; Lovett-Racke,Amy,E; Eagar,Todd,N; Greenberg,Benjamin,M; Racke,Michael,K; Cowell,Lindsay,G; Karandikar,Nitin,J; Frohman,Elliot,M; Monson,Nancy,L. "Memory B Cells from a Subset of Treatment-Naive Relapsing-Remitting Multiple Sclerosis Patients Elicit CD4+ T-cell Proliferation and IFN-gamma Production in Response to Myelin Basic Protein and Myelin Oligodendrocyte Glycoprotein." EUROPEAN JOURNAL OF IMMUNOLOGY. Vol. 40, no. 10. (October 2010.): 2942-2956.

Zein,Sima,S; Hu,Wei; Nessler,Stefan; Hemmer,Bernhard; Eagar,Todd; Kane,Lawrence,P; Leliveld,S,Rutger; Gocke,Anne,R; Lovett-Racke,Amy; Ben,Li,Hong; Hussain,Rehana; Elliot,Jeffrey; Puttaparthi,Krishna; Cravens,Petra,D; Petsch,Benjamin; Deming,Katherine; Stitz,Lothar; Racke,Michael,K; Korth,Carsten; Stuve,Olaf. "Pharmacological PrP-Silencing Accelerates CNS Autoimmune Disease Via TCR Signaling." NEUROLOGY. Vol. 74, no. 9. (March 2010.): A496-A496.

Ghoreschi,Kamran; Keller,Christina; Deng,Caishu; Brueck,Juergen; Feil,Susanne; Feil,Robert; Lovett-Racke,Amy,E; Racke,Michael,K; Dringen,Ralf; Roecken,Martin. "Fumarates improve Psoriasis and Multiple Sclerosis by inducing type II dendritic cells." JOURNAL OF INVESTIGATIVE DERMATOLOGY. Vol. 130, (September 2010.): S11-S11.

Racke,Michael,K; Peng,Hai-Yan; Akyol,Elif; Lovett-Racke,Amy,E; Pitt,David. "Neuroprotective Potential of Fumaric Acid Esters in a Model of Multiple Sclerosis." NEUROLOGY. Vol. 76, no. 9. (March 2011.): A385-A386.

Racke,Michael,K; Lovett-Racke,Amy,E. "Glatiramer Acetate Treatment of Multiple Sclerosis: An Immunological Perspective." JOURNAL OF IMMUNOLOGY. Vol. 186, no. 4. (February 2011.): 1887-1890.

Lovett-Racke,Amy,E; Yang,Yuhong; Racke,Michael,K. "Th1 Versus Th17: Are T Cell Cytokines Relevant in Multiple Sclerosis?." BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. Vol. 1812, no. 2. (February 2011.): 246-251.

Huss,David,J; Winger,Ryan,C; Cox,Gina,Mavrikis; Guerau-de-Arellano,Mireia; Yang,Yuhong; Racke,Michael,K; Lovett-Racke,Amy,E. "TGF-beta Signaling via Smad4 Drives IL-10 Production in Effector Th1 Cells and Reduces T-cell Trafficking in EAE." EUROPEAN JOURNAL OF IMMUNOLOGY. Vol. 41, no. 10. (October 2011.): 2987-2996.

Guerau-de-Arellano,Mireia; Smith,Kristen,M; Godlewski,Jakub; Liu,Yue; Winger,Ryan; Lawler,Sean,E; Whitacre,Caroline,C; Racke,Michael,K; Lovett-Racke,Amy,E. "Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity.." Brain. Vol. 134, (December 2011.): 3578-3589.

Almad,Akshata; Lash,A,Todd; Wei,Ping; Lovett-Racke,Amy,E; McTigue,Dana,M. "The PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice." EXPERIMENTAL NEUROLOGY. Vol. 232, no. 2. (December 2011.): 309-317.

Guerau-de-Arellano,Mireia; Smith,Kristen,M; Godlewski,Jakub; Liu,Yue; Winger,Ryan; Lawler,Sean,E; Whitacre,Caroline,C; Racke,Michael,K; Lovett-Racke,Amy,E. "Micro-RNA dysregulation in multiple sclerosis favours pro-inflammatory T-cell-mediated autoimmunity." BRAIN. Vol. 134, (December 2011.): 3575-3586.

Racke,Michael,K; Peng,Hai-Yan; Akyol,Elif; Lovett-Racke,Amy,E; Pitt,David. "Neuroprotective Potential of Fumaric Acid Esters in a Model of Multiple Sclerosis." NEUROLOGY. Vol. 76, no. 9. (March 2011.): A385-A386.

Smith,Alan,J; Liu,Yue; Peng,Haiyan; Beers,Rachel; Racke,Michael,K; Lovett-Racke,Amy,E. "Comparison of a Classical Th1 Bacteria Versus a Th17 Bacteria as Adjuvant in the Induction of Experimental Autoimmune Encephalomyelitis." JOURNAL OF NEUROIMMUNOLOGY. Vol. 237, no. 1-2. (August 2011.): 33-38.

Ghoreschi,Kamran; Brueck,Juergen; Kellerer,Christina; Deng,Caishu; Peng,Haiyan; Rothfuss,Oliver; Hussain,Rehana,Z; Gocke,Anne,R; Respa,Annedore; Glocova,Ivana; Valtcheva,Nadejda; Alexander,Eva; Feil,Susanne; Feil,Robert; Schulze-Osthoff,Klaus; Rupec,Rudolf,A; Lovett-Racke,Amy,E; Dringen,Ralf; Racke,Michael,K; Roecken,Martin. "Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells." JOURNAL OF EXPERIMENTAL MEDICINE. Vol. 208, no. 11. (October 2011.): 2291-2303.

Huss,David,J; Winger,Ryan,C; Cox,Gina,Mavrikis; Guerau-de-Arellano,Mireia; Yang,Yuhong; Racke,Michael,K; Lovett-Racke,Amy,E. "TGF-beta signaling via Smad4 drives IL-10 production in effector Th1 cells and reduces T-cell trafficking in EAE (vol 41, pg 2987, 2011)." EUROPEAN JOURNAL OF IMMUNOLOGY. Vol. 42, no. 11. (November 2012.): 3084-3084.

Lovett-Racke,Amy,E. "Research highlights: highlights from the latest articles in optimizing vaccine development.." Immunotherapy. Vol. 4, no. 5. (May 2012.): 469-471.

Lovett-Racke,Amy,E. "Research highlights: highlights from the latest articles in optimizing vaccine development.." Immunotherapy. Vol. 4, no. 5. (May 2012.): 469-471.

Lovett-Racke,Amy,E. "Glycan-specific T cells: an unexpected benefit of conjugated vaccines." IMMUNOTHERAPY. Vol. 4, no. 5. (May 2012.): 469-470.

Lovett-Racke,Amy,E. "Glycan-specific T cells: an unexpected benefit of conjugated vaccines." IMMUNOTHERAPY. Vol. 4, no. 5. (May 2012.): 469-470.

Peng,Haiyan; Akyol,Elif; Pitt,David; Lovett-Racke,Amy; Racke,Michael. "DIMETHYL FUMARATE PROTECTS THE CNS AGAINST EXCITOTOXICITY." MULTIPLE SCLEROSIS JOURNAL. Vol. 18, no. 9. (September 2012.): S7-S7.

Lovett-Racke,Amy,E. "Inhibiting the inhibitors promotes protective immunity." IMMUNOTHERAPY. Vol. 4, no. 5. (May 2012.): 471-471.

Lovett-Racke,Amy,E. "Inhibiting the inhibitors promotes protective immunity." IMMUNOTHERAPY. Vol. 4, no. 5. (May 2012.): 471-471.

Lovett-Racke,Amy,E. "'Helper' neutrophils promote antibody production." IMMUNOTHERAPY. Vol. 4, no. 5. (May 2012.): 470-470.

Lovett-Racke,Amy,E. "'Helper' neutrophils promote antibody production." IMMUNOTHERAPY. Vol. 4, no. 5. (May 2012.): 470-470.

Peng,Haiyan; Guerau-de-Arellano,Mireia; Mehta,Veela; Yang,Yuhong; Huss,David; Papenfuss,Tracey; Lovett-Racke,Amy; Racke,Michael. "Dimethyl fumarate inhibits dendritic cell maturation via NF-kB and ERK1/2-MSK1 signaling." JOURNAL OF NEUROIMMUNOLOGY. Vol. 253, no. 1-2. (December 2012.): 174-175.

Guerau-de-Arellano,Mireia; Alder,Hansjuerg; Ozer,Hatice,Gulcin; Lovett-Racke,Amy; Racke,Michael,K. "miRNA profiling for biomarker discovery in multiple sclerosis: From microarray to deep sequencing." JOURNAL OF NEUROIMMUNOLOGY. Vol. 248, no. 1-2. (July 2012.): 32-39.

Smith,Kristen,M; Guerau-de-Arellano,Mireia; Costinean,Stefan; Williams,Jessica,L; Bottoni,Arianna; Mavrikis Cox,Gina; Satoskar,Abhay,R; Croce,Carlo,M; Racke,Michael,K; Lovett-Racke,Amy,E; Whitacre,Caroline,C. "miR-29ab1 deficiency identifies a negative feedback loop controlling Th1 bias that is dysregulated in multiple sclerosis.." Journal of immunology. Vol. 189, no. 4. (August 2012.): 1567-1576.

Peng,Haiyan; Guerau-de-Arellano,Mireia; Mehta,Veela,B; Yang,Yuhong; Huss,David,J; Papenfuss,Tracey,L; Lovett-Racke,Amy,E; Racke,Michael,K. "Dimethyl Fumarate Inhibits Dendritic Cell Maturation via Nuclear Factor kappa B (NF-kappa B) and Extracellular Signal-regulated Kinase 1 and 2 (ERK1/2) and Mitogen Stress-activated Kinase 1 (MSK1) Signaling." JOURNAL OF BIOLOGICAL CHEMISTRY. Vol. 287, no. 33. (August 2012.): 28017-28026.

Peng,Haiyan; Guerau-de-Arellano,Mireia; Mehta,Veela,B; Yang,Yuhong; Huss,David,J; Papenfuss,Tracey,L; Lovett-Racke,Amy,E; Racke,Michael,K. "Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor ?B (NF-?B) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling.." Journal of Biological Chemistry. Vol. 287, no. 33. (August 2012.): 28017-28026.

Jukkola,Peter,I; Lovett-Racke,Amy,E; Zamvil,Scott,S; Gu,Chen. "K+ channel alterations in the progression of experimental autoimmune encephalomyelitis." NEUROBIOLOGY OF DISEASE. Vol. 47, no. 2. (August 2012.): 280-293.

Peng,Haiyan; Akyol,Elif; Pitt,David; Lovett-Racke,Amy; Racke,Michael. "DIMETHYL FUMARATE PROTECTS THE CNS AGAINST EXCITOTOXICITY." MULTIPLE SCLEROSIS JOURNAL. Vol. 18, no. 9. (September 2012.): S7-S7.

Smith,Kristen,M; Guerau-de-Arellano,Mireia; Costinean,Stefan; Williams,Jessica,L; Bottoni,Arianna; Cox,Gina,Mavrikis; Satoskar,Abhay,R; Croce,Carlo,M; Racke,Michael,K; Lovett-Racke,Amy,E; Whitacre,Caroline,C. "miR-29ab1 Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis." JOURNAL OF IMMUNOLOGY. Vol. 189, no. 4. (August 2012.): 1567-1576.

Huss,David,J; Winger,Ryan,C; Cox,Gina,Mavrikis; Guerau-de-Arellano,Mireia; Yang,Yuhong; Racke,Michael,K; Lovett-Racke,Amy,E. "TGF-beta Signaling via Smad4 Drives IL-10 Production in Effector Th1 Cells and Reduces T-cell Trafficking in EAE." EUROPEAN JOURNAL OF IMMUNOLOGY. Vol. 42, no. 11. (November 2012.): 3084-3084.

Peng,Haiyan; Guerau-de-Arellano,Mireia; Mehta,Veela; Yang,Yuhong; Huss,David; Papenfuss,Tracey; Lovett-Racke,Amy; Racke,Michael. "Dimethyl fumarate inhibits dendritic cell maturation via NF-kB and ERK1/2-MSK1 signaling." JOURNAL OF NEUROIMMUNOLOGY. Vol. 253, no. 1-2. (December 2012.): 174-175.

Guerau-de-Arellano,Mireia; Lovett-Racke,Amy; Racke,Michael. "T cell miRNA in multiple sclerosis pathogenesis." JOURNAL OF IMMUNOLOGY. Vol. 190, (May 2013.): -.

Guerau-de-Arellano,Mireia; Lovett-Racke,Amy; Racke,Michael. "T cell miRNA in multiple sclerosis pathogenesis." JOURNAL OF IMMUNOLOGY. Vol. 190, (May 2013.): -.

Fenn,Ashley,M; Smith,Kristen,M; Lovett-Racke,Amy,E; Guerau-de-Arellano,Mireia; Whitacre,Caroline,C; Godbout,Jonathan,P. "Increased micro-RNA 29b in the aged brain correlates with the reduction of insulin-like growth factor-1 and fractalkine ligand." NEUROBIOLOGY OF AGING. Vol. 34, no. 12. (December 2013.): 2748-2758.

Severin,Mary; Guerau-de-Arellano,Mireia; Lee,Priscilla; Racke,Michael; Lovett-Racke,Amy. "Differentially expressed microRNAs in multiple sclerosis patients alter regulatory T cells." JOURNAL OF NEUROIMMUNOLOGY. Vol. 275, no. 1-2. (October 2014.): 112-113.

Lee,Priscilla; Smith,Alan; Yang,Yuhong; Selhorst,Amanda; Racke,Michael; Lovett-Racke,Amy. "Critical contribution from antigen presenting cells for encephalitogenic T cells." JOURNAL OF NEUROIMMUNOLOGY. Vol. 275, no. 1-2. (October 2014.): 65-66.

Lee,Priscilla; Smith,Alan; Yang,Yuhong; Selhorst,Amanda; Racke,Michael; Lovett-Racke,Amy. "Critical contribution from antigen presenting cells for encephalitogenic T cells." JOURNAL OF NEUROIMMUNOLOGY. Vol. 275, no. 1-2. (October 2014.): 65-66.

Severin,Mary; Guerau-de-Arellano,Mireia; Lee,Priscilla; Racke,Michael; Lovett-Racke,Amy. "Differentially expressed microRNAs in multiple sclerosis patients alter regulatory T cells." JOURNAL OF NEUROIMMUNOLOGY. Vol. 275, no. 1-2. (October 2014.): 112-113.

Racke,Michael,K; Yang,Yuhong; Lovett-Racke,Amy,E. "Is T-bet a Potential Therapeutic Target in Multiple Sclerosis?." JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. Vol. 34, no. 8. (August 2014.): 623-632.

Peine,Kevin,J; Guerau-de-Arellano,Mireia; Lee,Priscilla; Kanthamneni,Naveen; Severin,Mary; Probst,G,Duane; Peng,Haiyan; Yang,Yuhong; VanGundy,Zachary; Papenfuss,Tracey,L; Lovett-Racke,Amy,E; Bachelder,Eric,M; Ainslie,Kristy,M. "Treatment of Experimental Autoimmune Encephalomyelitis by Codelivery of Disease Associated Peptide and Dexamethasone in Acetalated Dextran Microparticles." MOLECULAR PHARMACEUTICS. Vol. 11, no. 3. (March 2014.): 828-835.

Yang,Y; Winger,R,C; Lee,P,W; Nuro-Gyina,P,K; MINC,A; Larson,M; Liu,Y; Pei,W; Rieser,E; Racke,M,K; Lovett-Racke,A,E. "Impact of suppressing retinoic acid-related orphan receptor gamma t (ROR)gamma t in ameliorating central nervous system autoimmunity." CLINICAL AND EXPERIMENTAL IMMUNOLOGY. Vol. 179, no. 1. (January 2015.): 108-118.

Ding,Xiaoli; Yan,Yaping; Li,Xing; Li,Ke; Ciric,Bogoljub; Yang,Jingxian; Zhang,Yuan; Wu,Shuai; Xu,Hui; Chen,Wanjun; Lovett-Racke,Amy,E; Zhang,Guang-Xian; Rostami,Abdolmohamad. "Silencing IFN-gamma Binding/Signaling in Astrocytes versus Microglia Leads to Opposite Effects on Central Nervous System Autoimmunity." JOURNAL OF IMMUNOLOGY. Vol. 194, no. 9. (May 2015.): 4251-4264.

Lee,Priscilla,W; Yang,Yuhong; Racke,Michael,K; Lovett-Racke,Amy,E. "Analysis of TGF-beta 1 and TGF-beta 3 as regulators of encephalitogenic Th17 cells: Implications for multiple sclerosis." BRAIN BEHAVIOR AND IMMUNITY. Vol. 46, (May 2015.): 44-49.

Guerau-de-Arellano M, Liu Y, Meisen WH, Pitt D, Racke MK and Lovett-Racke AE. "Analysis of miRNA in Normal Appearing White Matter to Identify Altered CNS Pathways in Multiple Sclerosis." Brain Research. -.

Severin ME, Lee PW, Liu Y, Selhorst AJ, Gormley MG, Pei W, Guerau-de-Arellano, Racke MK and Lovett-Racke AE. "MicroRNAs Targeting TGFbeta Signaling Underlie the Regulatory T Cell Defect in Multiple Sclerosis." Science Translational Medicine. -.

Jones KJ, Lovett-Racke AE, Walker CL and Sanders VM. "CD4+ T Cells and Neuroprotection: Relevance to Motoneuron Injury and Disease." JOURNAL OF NEUROIMMUNE PHARMACOLOGY. -.

 

Reference Works

January 1992 Lovett A, McCarthy M, Frey T, Rice C, Wolinsky JS."Rubella-specific cytotoxic T-cell responses" . : A1334
January 1998 Racke MK, Trotter JL, Perrin PJ, June CH, Lovett-Racke AE."Decreased dependence of myelin basic protein-specific T cells on CD28-mediated costimulation in multiple sclerosis patients" . : A358
January 1998 Owens T, Segal BM, Racke MK, Lovett-Racke AE, Begolka WS, Miller SD."Tumour necrosis factor-alpha and lymphotoxin-alpha in the pathology of experimental autoimmune encephalomyelitis: is either one responsible or is there another ligand-mediated disease? Discussion" . : 849
January 1998 Lovett-Racke A, Trotter J, Lauber J, Perrin P, June C and Racke M."Decreased dependence of myelin basic protein-reative T cells on CD28-mediated costimulation in multiple sclerosis patients" . : 75
January 1998 Lovett-Racke A, Bittner P, Cross A, Carlino J and Racke M."Regulation of experimental autoimmune encephalomyelitis with insulin-like growth factor (IGF-1) and IGF-1/IGF binding protein-3 complex" . : 60
January 1998 Willenborg DO, Racke MK, Lovett-Racke AE, Hoffman LM, Karpus WJ, Owens T."Cytokines as intrinsic and exogenous regulators of pathogenesis in experimental encephalomyelitis - Discussion" . : 843
January 1998 Segal BM, Willenborg DO, Racke MK, Lovett-Racke AE, Hoffman LM, Karpus WJ, Begolka WS, Miller SD."Immune cell entry to the CNS - a focus for immunoregulation of EAE - Discussion" . : 844
January 1998 Begolka WS, Miller SD, Segal BM, Racke MK, Lovett-Racke AE."Antigen-driven regulation of experimental autoimmune encephalomyelitis - Discussion" . : 842
January 2001 Deng C, Hussain R, Lovett-Racke AE, Rocken M and Racke MK."Monomethylfumarate induces a Th2 immune response and suppresses experimental autoimmune encephalomyelitis" . : 96
January 2001 Lovett-Racke AE, Diab A, Deng C, Hussain R, Smith J and Racke MK."Th2 cytokine expression in the developing central nervous system" . : 101
January 2001 Ratts RB, Karandikar NJ, Lovett-Racke AE, Monson NL, Smith JD and Racke MK."An increased immune response to glatiramer acetate is short lived and may not explain its long-term therapeutic benefit in treated multiple sclerosis patients" . : 137
January 2001 Deng CS, Hussain R, Lovett-Racke A, Radu C, Minguela A, Ward S, Racke M."The tyrosine phosphatase SHP-1 deficiency enhances the T cell response and exacerbates experimental autoimmune encephalomyelitis" . : A1060
January 2002 Ghoreschi K, Deng C, Hussain RZ, Viale O, Reitmeier C, Lovett-Racke AE, Racke MK and Rocken M."Abrogating the pathogenicity of autoreactive T cells with anti-psoriatic agents" . : 8
January 2002 Ghoreschi K, Deng C, Hussain RZ, Reitmeier C, Lovett-Racke A, Racke MK, Rocken M."Therapeutic immune deviation abrogates pathogenicity of autoreactive T cells" . : 319
January 2002 Karandikar NJ, Crawford MP, Yan X, Ratts RB, Brenchley JM, Lovett-Racke AE, Douek DC, Koup RA, Racke MK."Induction and restoration of CD8+ T cell responses following glatiramer acetate (Copaxone) therapy in multiple sclerosis" . : S90
January 2002 Karandikar NJ, Crawford MP, Ratts RB, Brenchley JM, Ambrozak DR, Lovett-Racke AE, Douek DC, Koup RA, Racke MK."Treatment with glatiramer acetate (GA) induced and restores CD8+ T-cell responses in patients with multiple sclerosis" . : A246
January 2002 Karandikar NJ, Crawford MP, Ratts RB, Brenchley JM, Ambrozak DR, Lovett-Racke AE, Douek DC, Koup RA, Racke MK."Treatment with glatiramer acetate (GA; Copaxone) induces and restores CD8+ T-cell responses in patients with multiple sclerosis" . : A1046
January 2004 Lovett-Racke AE, Rocchini AE, Choy J, Northrop SC, Hussain RZ and Racke MK."Silencing T-bet prevents autoimmune demyelinating disease" . : 52
January 2004 Ratts R, Lovett-Racke A, Karandikar N and Racke MK."Characterization of chronically stimulated T cells in humans" . : 216
January 2004 Hansen B, Lovett-Racke AE, Hussain RZ, Northrop SC and Racke MK."The role of toll-like receptors in the pathogenesis of EAE" . : 57
January 2004 Rocchini AE, Choy J, Northrop SC, Hussain RZ, Sikder D, Racke MK and Lovett-Racke AE."The role of T-bet in the differentiation of encephalitogenic T cells" . : 62
January 2006 Cravens PD, Gocke AR, Northrop SC, Ben L, Hussain RZ, Racke MK and Lovett-Racke AE."The role of T-bet in the regulation of inflammation in the CNS" . : 64
January 2006 Gocke AR, Hussain RZ, Ben L, Lovett-Racke AE and Racke MK."Transcription modulation of the immune response by PPARalpha agonists ameliorates EAE" . : 164
January 2008 Smith AJ, Yang Y, Weiner J, Racke MK and Lovett-Racke AE."Defining the role of IL-23 in the differentiation of encephalitogenic T cells" . : 239
January 2008 Lovett-Racke AE, Gocke AR, Yang Y, Hussain R, Liu Y, Ben L, Cravens P and Racke MK."Role of T-bet in regulating autoimmune Th1 and Th17 cells" . : 158
January 2008 Harp C, Lovett-Racke A, Racke M, Frohman E and Monson N."B-T cell interactions in multiple sclerosis" . : 139
January 2008 Yang Y, Weiner J, Liu Y, Racke M and Lovett-Racke A."Defining autoreactive encephalitogenic T cells" . : 234
January 2009 Racke M, Yang Y, Liu Y, Smith A, Winger R, Peng H, Cravens P, Lovett-Racke A."T-bet, not cytokine expression, determines T-cell encephalitogenicity" . : S59
January 2009 Nessler S, Hu W, Hemmer B, Eagar T, Kane L, Leliveld R, Muller-Schiffmann A, Gocke A, Lovett-Racke A, Li-Hong B, Hussain R, Breil A, Elliott J, Carlson P, Cravens P, Singh MP, Petsch B, Stitz L, Racke M, Korth C, Stuve O."Prion protein is a key regulator of T-cell activation, differentiation and survival" . : S192
January 2009 Hu W, Nessler S, Hemmer B, Eagar T, Kane L, Leliveld R, Muller-Schiffmann A, Gocke A, Lovett-Racke A, Ben LH, Hussain R, Breil A, Elliott J, Carson P, Cravens P, Singh M, Petsch B, Stitz L, Racke M, Korth C, Stuve O."Prior Protein is a key regulator of T cell activation, differentiation and survival" . : A280
October 2010 Huss D, Winger R, Peng H,."TGF-beta enhances Th1 cell activation yet reduces EAE disease course by promoting T cell self-regulation" Amsterdam. : 140
November 2010 Smith K, Guerau-de-Arellano M, Bottoni A, et al."MicroRNAs Modulate Immune Function in Multiple Sclerosis" Amsterdam. : 121
November 2010 Peng H, Akyol E, Guerau M, et al."The dual function of Dimethyl Fumarate in Multiple Sclerosis" Amsterdam. : 98
March 2011 Racke MK, Peng HY, Akyol E, Lovett-Racke AE, and Pitt D."Neuroprotective Potential of Fumaric Acid Esters in a Model of Multiple Sclerosis" Philadelphia. : A385
December 2012 Peng HY, Guerau-de-Arellano M, Mehta V, Yang YH, Huss D, Papenfuss T, Lovett-Racke A, and Racke M."Dimethyl Fumarate Inhibits Dendritic Cell Maturation via NF-kB and ERK1/2-MSK1 Signaling" Amsterdam. : 174
December 2012 Lee P, Yang Y, and Lovett-Racke A."Defining the Minimal Signals Necessary to Generate an Encephalitogenic T Cell" Amsterdam. : 72
September 2012 Peng HY, Akyol E, Pitt D, Lovett-Racke A, and Racke M."Dimethyl Fumarate Protects the CNS Against Excitotoxicity" London. : S7
May 2013 Zhang GX, Yan YP, Ding XL, Li K, Ciric B, Yang JX, Wu S, Xu H, Chen WJ, Lovett-Racke A, and Rostami A."IFN-gamma Signaling in Astrocytes and Microglia has Opposite Roles in CNS Autoimmunity" Bethesda.
May 2013 Guerau-de-Arellano M, Lovett-Racke A and Racke M."T Cell miRNA in Multiple Sclerosis Pathogenesis" Bethesda.
October 2014 Severin M, Guerau-de-Arellano M, Lee P, Racke M, and Lovett-Racke A."Differentially Expressed MicroRNAs in Multiple Sclerosis Patients Alter Regulatory T Cells" Amsterdam. : 112
October 2014 Lee P, Smith A, Yang Y, Selhorst A, Racke M and Lovett-Racke A."Critical Contribution from Antigen Presenting Cells for Encephalitogenic T Cells" Amsterdam. : 65

Presentations

"Immune Deviation as a Potential Therapy for Multiple Sclerosis." Presented at Rheumatology Seminar, Dallas. (January 2003)

"Immune Mechanisms and Autoimmune Injury." Presented at Neurology Residence Conference, Dallas. (January 2003)

"Immune Mechanisms and Autoimmune Injury." Presented at Neurology Residence Conference, Dallas. (September 2004)

"Therapeutic Potential of Gene Silencing in Immune-mediated Demyelinating Disease." Presented at Neurology Grand Rounds, Dallas. (January 2004)

"Silencing T-bet prevents autoimmune demyelinating disease." Presented at 7th Congress of the International Society for Neuroimmunology, Venice, IT|ITA. (September 2004)

"Development of New Therapeutic Agents for Multiple Sclerosis." Presented at UT Southwestern Medical Center, Dallas. (January 2005)

"Therapeutic Potential of siRNA for the Treatment of Multiple Sclerosis." Presented at Consortium of Multiple Sclerosis Center Annual Meeting, Orlando. (June 2005)

"Therapeutic Potential of siRNA for Multiple Sclerosis." Presented at Molecular Virology, Immunology and Medical Genetics Seminar, Columbus. (April 2005)

"Therapeutic Benefit of Silencing T-bet in Autoimmune Demyelinating Disease." Presented at Neuroimmunology Branch Seminar, Bethesda. (May 2005)

"T-bet Regulates the Fate of Th1 and Th17 Lymphocytes in Autoimmunity." Presented at Americas Committee for the Treatment and Research in Multiple Sclerosis Meeting, Chicago. (October 2006)

"Therapeutic Potential of siRNA for Multiple Sclerosis." Presented at 8th Annual Frontiers in Neuroscience Research Day, Charleston. (March 2007)

"Multiple Sclerosis." Presented at Integrated Biomedical Science Graduate Program Seminar, Columbus. (June 2007)

"Role of T-bet in Autoreactive Th1 and Th17 Cells." Presented at Immunology Seminar, Columbus. (May 2008)

"Identifying Therapeutic Targets for Multiple Sclerosis." Presented at Molecular Virology, Immunology and Medical Genetics Seminar, Columbus. (February 2008)

"Identifying Therapeutic Targets for Multiple Sclerosis." Presented at OSU Molecular Virology, Immunology and Medical Genetics Seminar, Columbus. (February 2008)

"Defining the Role of T-bet in Encephalitogenic Th1 and Th17 Cells." Presented at Tykeson Fellows Conference on Multiple Sclerosis, Chicago. (November 2008)

"Silencing T-bet Suppresses Th1 and Th17 Cell Differentiation." Presented at Experimental Biology 2008, San Diego. (April 2008)

"Role of T-bet in Regulating Autoimmune Th1 and Th1 Cells." Presented at Congress of the International Society for Neuroimmunology, Fort Worth. (October 2008)

"T-bet or not T-bet, that is the question (in autoimmunity)." Presented at OSU Molecular Virology, Immunology & Medical Genetics Seminar, Columbus. (November 2009)

"Experimental Autoimmune Encephalomyelitis: A Model of Multiple Sclerosis." Presented at University Laboratory Animal Resources Seminar, Columbus. (September 2009)

"Identifying microRNA Differentially Expressed in T Cells of MS Patients." Presented at American Association of Immunologists Annual Meeting, Baltimore. (May 2010)

"T-bet or not T-bet: That is the Question in Autoimmunity." Presented at Immunology Seminar, San Antonio. (April 2010)

"Therapeutic Potential of Small RNAs in Multiple Sclerosis." Presented at Kyoto Neuroimmunology Conference, Kyoto, JP|JPN. (August 2010)

"Multiple Sclerosis." Presented at Integrated Biomedical Science Graduate Program Seminar, Columbus. (August 2010)

"Small RNAs...Big Results: Potential Roles of siRNA and miRNA in Multiple Sclerosis." Presented at Neuroimmunology Seminar, Dallas. (January 2011)

"Defining the Role of miRNA in Susceptibility to Multiple Sclerosis." Presented at Neurology Seminar, Baltimore. (October 2011)

"Small RNAs: Susceptibility Factors and Potential Therapies for Multiple Sclerosis." Presented at Seminar, Ann Arbor. (January 2012)

"Small RNAs...Big Results: Potential Roles of siRNA and miRNA in Multiple Sclerosis." Presented at Molecular Cellular and Developmental Biology Program Student Seminar, Columbus. (February 2012)

"Potential of Small Interfering RNAs as Therapies for Multiple Sclerosis." Presented at Immunology Seminar, Toledo. (October 2012)

"Role of miRNA in T Cells in Susceptibility to Multiple Sclerosis." Presented at Americas Committee for the Treatment and Research in Multiple Sclerosis Meeting, San Diego. (June 2012)

"Molecular Characterization of Pathogenic T Cells in Multiple Sclerosis." Presented at Center for Microbial Interface Biology Work in Progress Seminar, Columbus. (February 2013)

"Road to PI." Presented at Center for Microbial Interface Biology Seminar, Columbus. (June 2013)

"Development of Small RNA-Based Therapies for Multiple Sclerosis." Presented at Integrated Biomedical Science Graduate Program Seminar, Columbus. (March 2013)

"Are miRNAs Susceptibility Factors for Multiple Sclerosis." Presented at Center for Microbial Interface Biology Work in Progress Seminar, Columbus. (June 2014)

"Are miRNAs Susceptibility Factors for Multiple Sclerosis?." Presented at Immunology Seminar, Farmington. (March 2014)

"Small RNAs...Big Results: Potential Roles of siRNA and miRNA in Multiple Sclerosis." Presented at Molecular Cellular and Developmental Biology Program Student Seminar, Columbus. (February 2014)

"Contribution of EAE to Understanding and Treating Multiple Sclerosis." Presented at National Institutes oh Health 40 Years of Neuroimmunology, Warrenton. (April 2015)

 

Professional Activities

present Challenge Grants. National Institutes of Neurological Disorders and Stroke.
present Neuroscience Training Study Section - Ad hoc member. National Institutes of Health.
present Autoimmunity Center of Excellence Study Section - Ad hoc member. National Institutes of Health.
present Immunology Fellowship and Academic Research Enhancement Award Study Section - Ad hoc member. National Institutes of Health.
2015 - present Hypersensitivity Autoimmune and Immune-mediated Diseases Study Section - Permanent Member. National Institutes of Health.
2015 - present Chair - Immunology Pilot Project Committee. National Multiple Sclerosis Society.
- 2005 Ad-hoc. Medical Research Council.
- 2006 Clinical Neuroimmunology and Brain Tumor Study Section Ad-hoc. National Institutes of Neurological Disorders and Stroke.
2004 - 2008 Pilot Project. National Multiple Sclerosis Society.
2009 - 2014 Advisory Committee Member. National Multiple Sclerosis Society.
 

Unpublished Works

Severin ME, Lee PW, Liu Y, Selhorst AJ, Gormley MG, Pei W, Guerau-de-Arellano, Racke MK and Lovett-Racke AE. MiRNAs Targeting TGFbeta signaling Underlie the Treg Defect in Multiple Sclerosis. September 2015.

Lee PW, Smith AJ, Yang Y, Selhorst AJ, Racke MK and Lovett-Racke AE. IL-23R-activated STAT3/STAT4 Signaling is Essential for Th1 and Th17 Cell-mediated Neuroinflammation. January 0.

Lee PW, Yang Y, Huss D, Liu Y, Pei W, Racke MK and Lovett-Racke AE. Molecular Profiles Unique to Encephalitogenic T Cells in Multiple Sclerosis. January 0.

Lee PW, Selhorst AJ, Pei W, Liu Y, Racke MK and Lovett-Racke AE. Vitamin D Signaling on Neurons During Early Life Promotes CNS Homeostasis and Decreases Susceptibility of Developing Autoimmune Encephalomyelitis. January 0.

Guerau-de-Arellano M, Liu Y, Meisen WH, Pitt D, Racke MK and Lovett-Racke AE. Analysis of miRNA in Normal Appearing White Matter to Identify Altered CNS Pathways in Multiple Sclerosis. September 2015.