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Abhay Satoskar, PhD


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320 W 10th Ave
Columbus, OH 43210

Phone: (614) 292-3243

Email: satoskar.2@osu.edu

 

Current OSU Appointments

Professor, Pathology

Professor, Microbiology Admin

 

Advising Narrative

Biological Sciences
2005 Denman Undergrad Research Forum: 1st Place Biological Sciences2006 College of Biological Sciences Undergrad Research Colloquium participant2006 Denman Undergrad Research Forum: 3rd Place Biological Sciences2006 College of Biological Sciences Undergrad Research Colloquium participant
Biological Sciences
Biological Sciences
2006 Denman Undergraduate Research Forum4th Place - Biological Sciences2006 College of Biological Sciences Undergrad Research Colloquium participant
2007 McGraw-Hill for outstanding research, Central Ohio (High school)2007 First Place, Biology Teachers Award, State of Ohio (High school)2007 First Place, Future Physician-Scientist Award, State of Ohio (High school)2007 Fourth Place for Science and Medicine, International INTEL ISEF Competition
2008 Denman Undergrad Research Forum: 1st Place Biological Sciences2008 College of Biological Sciences Undergrad Research Colloquium participant

Books

Medical Parasitology

 

Licenses

1989 - present General Physician: Maharashtra Medical Council
 

Chapters in Books

Cutaneous leishmaniasis.

Hydatid disease

Immunological Control of Toxoplasma gondii and Appropriate Vaccine Design

Leishmaniasis: Does Interleukin-13 (IL-13) Play a Significant Role in the Disease Process?

Macrophage migration inhibitory factor (MIF) & weight loss

MIF in Parasitic and Helmithic Infections

Immunoregulation of Chiclero’s Ulcer

The Role of Chemokines in Leishmaniasis

Taeniasis and Cysticercosis

Sex Differences in Response to Parasites

 

Conferences

Essential role of natural killer cells in regulating IgG2a production in vivo revealed in a novel murine model of specific NK cell deficiency

Inducible costimulator protein (ICOS) regulates both Th1 and Th2 responses to cutaneous leishmaniasis

Macrophage migration inhibitory factor plays a role in acute trypanosoma cruzi infection

STAT1-mediated IFN-signaling pathway is indispensable for the development of protective immunity against cutaneous leishmaniasis

Stat-4 mediated IL-12 signaling pathway is critical for development of protective immunity in experimental cysticercosis

Macrophage migration inhibitory factor (MIF) plays a role in the relapses of experimental autoimmune encephalomyelitis (EAE)

Macrophage migration inhibitory factor involves in atherosclerosis by regulating matrix-degrading cysteine protease and metalloprotease expression

Integrated studies on the M32 family of carboxypeptidases: structural, mechanistic and functional insights

Critical role for macrophage migration inhibitory factor (MIF) in the relapses of experimental autoimmune encephalomyelitis (EAE)

Integrated studies on the M32 family of carboxypeptidases: structural, mechanistic and functional insights

Genetic differences in host susceptibility of mice to Leishmania mexicana revealed in a low dose ear infection model

Stat-1 deficiency increases host resistance and reduces hepatic immunopathology during visceral Leishmaniasis

IL-27R (WSX-1/TCCR) gene deficient mice display enhanced resistance to Leishmania donovani infection but develop severe liver immunopathology

STAT1 plays distinct role in determining outcome of L-donovani infection in C57BL/6 and BALB/c mice

The chemokine receptor CXCR3 is not required for host resistance to murine visceral leishmaniasis

Role PI-3 Gamma in pathogenesis of cutaneous leishmaniasis caused by L-mexicana

PI3K-gamma: Developing immune targets for the treatment of multiple sclerosis

Targeting phosphoinositide 3-kinase gamma (PI3K gamma) in the treatment of cutaneous leishmaniasis caused by L. mexicana

CNS-immune interactions: External influences as therapeutic interventions

The Role of Macrophage Migration Inhibitory Factor (MIF) as a Novel Therapeutic Target for Diabetes Treatment

Macrophage migration inhibitory factor promotes central nervous system pathology in a model of neuroinflammation

Compounds with antileishmanial activity isolated from the stems of Pentalinon andrieuxii

Generation and characterization of a CXCR3-EGFP bicistronic reporter (CIBER) mouse reveals phenotypically and functionally distinct populations of innate CD8+T cells

Synthesis and modification of natural sterols possessing antileishmanial activity

Synthesis of sterols with antileishmanial activity from Pentalinon andrieuxii

Differential roles for Th1 transcription factors STAT1 and STAT4 during visceral leishmaniasis

Cordifolide A, a sulfur-containing clerodane diterpene glycoside from Tinospora cordifolia

Antileishmanial activity of bisbenzylisoquinoline alkaloids from the genus Thalictrum

Regulation of inflammatory diseases by cestode antigens: multiple receptors and a possible common pathway

 

Degrees

1989 M.D., University of Bombay

1992 Ph.D., University of Strathclyde

 

Editorial Activities

1999 - present Memorias Do Instituto Oswaldo Cruz
1999 - 2008 The Journal of Immunology
2000 - present Transactions of the Royal Society of Tropical Medicine and Hygiene
2003 - present Immunology
2003 - present Cellular Immunology
2004 - present International Immunology
2004 - present Parasite Immunology
2004 - present Nitric oxide: Biology and Chemistry
2004 - present Trends in Parasitology
2004 - present Clinical and Experimental Immunology
2005 - present Clinical Infectious Diseases
2005 - present Brain, Behavior and Immunity
2005 - present American Journal of Respiratory & Critical Care Medicine
2005 - present Immunology Letters
2005 - present Experimental Parasitology
2005 - present Infection and Immunity
2005 - present Laboratory Investigation
2005 - 2009 The Journal of Infectious Diseases
2006 - present Microbes and Infection
2006 - present Vaccine
2007 - present The Open Parasitology Journal
2007 - present The Journal of Leukocyte Biology
2007 - present The Journal of Experimental Medicine
2007 - present The FASEB Journal
2007 - present Liver International
2007 - present Cytokine
2007 - present Phytochemistry
2007 - present BMC Infectious Diseases
2007 - present BMC Immunology
2007 - present Journal of Gerontology
2007 - present Case Reports in Medicine
2008 - present Proceedings of the National Academy of Sciences USA
2008 - present Asian Pacific Journal of Tropical Medicine
2008 - present The Journal Immunology
2008 - present Molecular and Biochemical Parasitology
2008 - present Journal of Biomedicine and Biotechnology
2009 - present Nephrology Dialysis Transplantation
2009 - present British Journal of Dermatology
2009 - present PLoS Pathogens
2009 - present American Journal of Physiology Cell Physiology
2009 - present Journal of Investigative Dermatology
2009 - present FEBS Letters
2009 - present Faculty of 1000 Biology
2009 - present Antimicrobial Agents and Chemotherapy
2010 - present Experimental Parasitology
 

Honors

1990 - 1992 University Merit Scholarship. University of Bombay.
1992 - present Rameshwardas Birla Trust Scholarship. Rameshwardas Birla Trust.
1992 - present Dr. C. K. Deshpande Gold Medal. University of Bombay.
1992 - 1996 David Livingston Bursary. University of Strathclyde.
1992 - 1996 Overseas Research Student Award. Committee of Vice Chancellors and Principals of UK, London.
1993 - present Travel Award. British Section of Society for Protozoology.
1995 - present Travel Award. Scuola Superiore D'Immunologia Ruggero Ceppellini, Positano, Italy.
1996 - present Travel Award. Britis Section of Society for Protozoology.
2000 - present Visiting Guest Lecturer. University of Cape Town.
2002 - present Visiting Scientist Award. University of Cape Town.
2003 - present American Association of Immunologists Junior Faculty Travel Award. American Association of Immunologists.
2005 - present Dean's Award for Undergraduate Research Mentoring. Ohio State University, College of Biological Sciences.
 

Journal Articles

 

Presentations

Mechanisms of sex-determined susceptibility to L. mexicana

Mechansims of sex-determined resistance to L. mexicana

Distinct role of IL-4 in regulating immune response during visceral and cutaneous leishmaniasis

Distinct role of IL-4 in regulating immune response during visceral and cutaneous leishmaniasis

Distinct role of IL-4 in regulating immune response during visceral and cutaneous leishmaniasis

IL-4 is involved in pathogenesis of cutaneous leishmanaisis caused by L. mexicana

Role of IL-4 in cutaneous and visceral leishmaniasis

Distinct roles of IL-4 in determining outcome of visceral and cutaneous leishmanaisis

Leishmania spp: Models of intracellular parasitsm

STAT6 signaling plays a critical role in pathogenesis of CL caused by L. mexicana

NK cells are not required for resolution of cutaneous leishmaniasis caused by L. major

Immune mechanisms mediating gender-associated resistance to leishmaniasis

Mice deficient for migration inhibitory factor (MIF-/-) become susceptible to L. major

Roles of Th2-type cytokines in regulation of host responses during leishmanaisis

Mice lacking NK cells mount an efficient Th1 response and control CL caused by L. major; STAT6 signaling pathway is involved in mediating susceptibility to CL caused by L. mexicana

Control of cutaneous L. mexicana infection in L-selectin gene deficient mice.

Mechansims of immunity in leishmaniasis: A complex puzzle

Mechansims of immunity in leishmaniasis: A complex puzzle

Role of IL-4 and STAT6 signaling pathway in pathogenesis of CL caused by L. mexicana

Mechansims of immunity in leishmaniasis: A complex puzzle

Mechansims of IL-4 and STAT6-mediated susceptibility to L. mexicana

MIF: A critical mediator of inflammation and immunity

Mechanisms of immunoregulation in leishmanaisis

Mechanisms of immunity in leishmaniasis

Cytokines and regulation of immunity against leishmanaisis

Distinct roles of IL-4 and IL-13 in cutaneoues and viscerla leishmanaisis

Mechanisms of immunity in visceral and cutaneous leishmaniasis

Distinct roles of STAT1 and T-bet in determining outcome of visceral leishmaniasis

STAT-1 mediated signaling induces hepatic immunopathology and also mediates susceptibility to L. donovani

Role of sex hormones in regulation of immunity to L. mexicana

Role of chemokine in mediating immunity against cutaneous leishmaniasis

Mechanisms of immunity to Leishmania: A complex puzzle

Distinct roles of STAT1 and T-bet in determining outcome of visceral leishmaniasis

Distinct roles of STAT1 and T-bet in determining outcome of visceral leishmaniasis

Mechanisms of immunity and immune evasion in protozoan infections

Distinct roles of TH1-specific transcription factors stat1 and T-bet in regulating immunity to leishmania

Distinct roles of STAT1 and T-bet in visceral leishmaniasis

Distinct roles of STAT1 and T-bet in visceral leishmaniasis

Distinct roles of STAT1 and T-bet in determining outcome of viscerla leishmaniasis

Distinct roles of STAT1 and T-bet in visceral leishmaniasis

Distinct roles of STAT1 and T-bet in visceral leishmaniasis

Role of MIF in pathogenesis of EAE

Distinct roles of STAT1 and T-bet in visceral leishmaniasis

Differential role of STAT1 in regulating immunity against visceral and cutaneous leishmanaisis

Mechanisms of immunoregulation in visceral and cutaneous leishmanaisis

Targeting PI3Kg to block entry of Leishmania into phagocytes: A new strategy to treat cutaneous leishmaniasis

Denying access to safe havens to prevent insurgency: A new strategy for treating infections caused by intracellular pathogens

Denying access to safe havens to prevent insurgency: A new strategy for treating infections caused by intracellular pathogens

Role of sex hormones in regulation of immunity to leishmaniasis

Role of sex hormones in immunity to leishmaniasis

Role of MIF in immunity and inflammation

Denying access to safe havens to prevent insurgency: A new strategy for treating infections caused by intracellular pathogens

Immunological defects in BALB/c mice: How many more to find?

Denying access to safe haves to prevent insurgency: A novel strategy to treat infections caused by Leishmania

Mechanisms of immunoregulation in leishmaniasis

Denying access to safe haves to prevent insurgency: A novel approach to treat leishmaniasis

Denying access to safe havens: A novel strategy to treat leishmaniasis

Careers in biomedical research

Diagnosis and clincial management of leishmanaisis

Denying access to safe haves by targeting PI3Kg: A new strategy to treat leishmanaisis

Role of PI3Ks in pathogenesis of cutaneous leishmaniasis caused by L. mexicana

Denying access to safe havens to prevent insurgency: A novel strategy to treat infections caused by intracellular pathogens

Distinct roles of STAT1 in visceral and cutaneous leishmaniasis

Denying access to safe haves to prevent insurgency: A novel approach to treat leishmaniasis

Denying access to safe haves by targeting PI3Kg: A new strategy to treat leishmanaisis

Denying access to safe havens to prevent insurgency: A new strategy for treating infections caused by intracellular pathogens

Denying access to safe havens by targeting PI3Kg: A new strategy to treat leishmanaisis

Targeting PI3Kg: A novel strategy to treat infections caused by obligate intracellular pathogens

STAT1 in T cells palys a critical role in immunity against L. major by mediating recrutiment of Th1 cells to the site of infection

Distinct roles of STAT1 in determining outcomes of CL and VL

Role of STAT1 signaling in immunity to leishmanaisis

Leishmania species: models of intracellular parasitism.

 

Professional Activities

2001 - present Adhoc Reviewer for Research Grants. National Research Foundation, South Africa.
2002 - present Reviewer for Research Grants. Cape Biotech Initiative, South Africa.
2003 - present Reviewer for Research Grants. Sheikh Hamdan Medical Research Grant Foundation, Dubai, UAE.
2003 - present Adhoc Reviewer for Leishmania Special Study Section. NIH.
2004 - present Ad hoc Reviewer for Research Grants. Uniformed Services University for Health Sciences.
2004 - present Adhoc Reviewer for IDM Study Section. NIH.
2004 - present Adhoc Reviewer for PTHE Study Section. NIH.
2005 - present Ad hoc Reviewer, Program Projects. Wellcome Trust, UK.
2005 - present Adhoc Reviewer for IDM Study Section. NIH.
2006 - present External Examiner for Ph.D.. McGill University, Montreal, Canada.
2006 - present External Examiner for Masters and Ph.D.. University of Cape Town, South Africa.
2006 - present Adhoc Reviewer, Leishmaniasis Panel. US Army Medical Research and Materiel Command’s (USAMRMC) Military Infectious Disease Research Program (MIDRP).
2006 - present Adhoc Reviewer for Tropical Medicine Research Centers RFA Study Section. NIH.
2007 - present Adhoc Reviewer, Viral vaccine panel. Joint Science and Technology Office for Chemical and Biological Defense (JSTO-CBD), Department of Defense.
2007 - present Adhoc Reviewer, Leishmaniasis Panel. US Army Medical Research and Materiel Command’s (USAMRMC) Military Infectious Disease Research Program (MIDRP).
2007 - present External Examiner for Ph.D.. Sanjay Gandhi Postgraduate Institute for Medical Sciences, Lucknow, India.
2007 - present Examiner for Ph.D.. University of Pune, India.
2007 - present Promotion and Tenure Review. Indian Institute of Technology, Kharagpur, India.
2007 - present Ad hoc Reviewer, Program Projects. Wellcome Trust, UK.
2008 - present Adhoc Reviewer for Research Grants. US Army Medical Research and Materiel Command’s (USAMRMC) Military Infectious Disease Research Program (MIDRP).
2008 - present Promotion and Tenure Review. School of Medicine, Trinity College, Dublin, Ireland.
2008 - present Adhoc Reviewer for Research Grants. US Airforce Medical Research Program.
2008 - present Grant Reviewer, Leishmaniasis Panel. American Institute of Biological Sciences and Department of Defense.
2009 - present Adhoc Reviewer for NIAID Integrative and Collaborative Approaches to Research SEP. NIH.
2009 - present Teaching. WWAMI Program in Medicine, University of Alaska, Anchorage.
2009 - present Adhoc Reviewer for International Collaborations for Infectious Disease Research (ICIDR), Parasitology SEP. NIH.
2010 - present Swiss National Science Foundation.
2010 - present Visiting Professor. University of Anchorage, Alaska, School of Medicine WAMMI Program. Anchorage, AK.
2003 Adhoc Reviewer for TMP Study Section. NIH.