Gebreyes, Wondwossen

Research Summary
The major areas that my research is particularly focused are antimicrobial resistance, genotypic diversity and detection methods development of foodborne zoonotic pathogens. Specific activities in my laboratory include molecular characterization of genetic elements such as antimicrobial resistance genes, class-I integrons, and plasmids in strains of leading food safety problems such as multi-drug resistant ones.

The work in our laboratory mainly focuses on swine. Therefore, results generated from our studies have direct relevance to the Pork industry. In addition, as we are dealing with foodborne pathogens that are capable of infecting multiple host specieis, thefindings have significant impact on human health as well as food safety in other animal hosts.

In addition I collaborate with other experts in viral foodborne pathogens (mainly norovirus) and parasitic foodborne hazards (Ascaris, Trichinella and Toxoplamsa).

Other expertise in our laboratory include evaluation of DNA fingerprinting method for foodborne pathogens and comparative anlysis of antimicrobial resistance among Salmonella isolates from humans and swine.

Future Research
Development of molecular diagnostic/ detection methods using real-time PCR and microarray systems that enable accurate and rapid detection of multiple bacterial and viral foodborne pathogens simultaneously.

Professional Training and Experience
Diplomate, American College of Veterinary Preventive Medicine, ACVPM, 2002
Ph.D., North Carolina State University, Comparative Biomedical Sciences, 2001
DVM, Addis Ababa University, Veterinary Medicine, 1990

Publications (partial lisiting)
Thakur S, Morrow WE, Funk JA, Bahnson PB, Gebreyes WA. (2006) Molecular epidemiologic investigation of Campylobacter coli in swine production systems, using multilocus sequence typing., Applied Environ Microbiol., 72 (8), 5666-9

Gebreyes WA, Thakur S, Morrow WE. (2006) Comparison of prevalence, antimicrobial resistance, and occurrence of multidrug-resistant Salmonella in antimicrobial-free and conventional pig production, J Food Prot, 69 (4), 743-8

Gebreyes WA, Altier C, Thakur S. (2006) Molecular epidemiology and diversity of Salmonella serovar Typhimurium in pigs using phenotypic and genotypic approaches., Epidemiol Infect, 134 (1), 187-98

Thakur S, Gebreyes WA. (2005) Campylobacter coli in Swine Production: Antimicrobial Resistance Mechanisms and Molecular Epidemiology., J Clin Microbiol., 43 (11), 5705-14

Thakur S, Gebreyes WA. (2005) Prevalence and antimicrobial resistance of Campylobacter in antimicrobial-free and conventional pig production systems., J Food Prot, 68 (11), 2402-10

Contact
Wondwossen Gebreyes, DVM, PhD
Diplomate ACVPM
Associate Professor
Department of Veterinary Preventive Medicine
The Ohio State University
A100R Sisson Hall
1920 Coffey Rd.
Columbus, Ohio 43210
Ph: (614) 292-9559
Fx: (614) 292-4142