Center for Microbial Interface Biology  


CMIB Membership

Burkhard, Mary Jo

Mary Jo BurkhardMary Jo Burkhard, DVM, PhD, Diplomate American College of Veterinary Pathologists (Clinical Pathology), is an Assistant Professor in the Department of Veterinary Biosciences. She joined the Ohio State University in 2004. Dr. Burkhard's research focuses on the mucosal transmission and immunopathogenesis of lentiviruses such as human immunodeficiency virus (HIV).  Her current studies are directed towards understanding the mucosal immunopathogenesis of feline immunodeficiency virus (FIV) infection.  FIV is closely related to HIV and can be used to understand the mechanisms of lentiviral transmission as well as evaluate intervention strategies.  Specific areas of focus are (1) the role of cell-associated versus cell-free virus, (2) loss of mucosal immune effector cells during infection, and (3) what immune responses are important to induce by vaccination. 

Selected publications

Burkhard MJ, Dean GA.  Transmission and immunopathogenesis of FIV in cats as a model for HIV.  Current HIV Research 2003; 1:15-29. 

Leavell S, Wright B, Scappino L, Sirriyah J, Chen C, Clements JD, Burkhard MJ.  Use of the mucosal adjuvant LT(R192G) to enhance FIV-specific immune responses.  Vaccine, 2005; 23:1471-8. 

Howard KE, Fisher IL, Dean GA, Burkhard MJ.  Methodology for isolation and phenotypic characterization of feline small intestinal leukocytes. Journal Immunological Methods 302:36-53, 2005. 

Howard KE, Burkhard MJ.  FIV infection induces unique changes in phenotype and cellularity in the medial iliac lymph node and intestinal IEL.  In press, AIDS Research and Human Retroviruses.   

Assogba BD, Leavell SE, Porter K, Burkhard MJ.  Mucosal administration of low dose cell-associated feline immunodeficiency virus promotes viral latency.  In press, Journal of Infectious Diseases.

Burkhard Laboratory Personnel

Sarah Leavell Research Laboratory and Flow Cytometric Supervisor
Barnabe Assogba, PhD Post-Doctoral Researcher
Surender Kumar, BVSc & AH MS Candidate, Veterinary Biosciences Program

Contact
e-mail: burkhard.19@osu.edu
phone: 247-8024

344 VAMB
Veterinary Biosciences
Columbus, Ohio 43210

Links

VBS link
Burkhard link
Department of Veterinary Biosciences




 


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